| Sands Capital Alternatives, LLC | 18.68% | New | 4,230,926 | $114.6M |
| Samsara Biocapital, LLC | 5.52% | New | 2,480,310 | $67.2M |
| T. Rowe Price Investment Management, Inc. | 0.04% | New | 2,202,597 | $59.7M |
| ARK Investment Management | 0.24% | New | 1,373,959 | $37.2M |
| Braidwell LP | 1.13% | New | 1,083,983 | $29.4M |
| Alliancebernstein L.P. | 0.01% | New | 1,003,077 | $27.2M |
| HHLR Advisors, LTD. | 3.11% | New | 956,462 | $25.9M |
| BlackRock, Inc. | 0.00% | New | 911,445 | $24.7M |
| Millennium Management | 0.02% | New | 865,764 | $23.5M |
| FMR LLC | 0.00% | New | 829,424 | $22.5M |
| Pura Vida Investments, LLC | 55.35% | New | 755,909 | $20.5M |
| Emerald Advisers, LLC | 0.41% | New | 647,183 | $17.5M |
| Artisan Partners Limited Partnership | 0.03% | New | 613,744 | $16.6M |
| Deerfield Management Company, L.P. | 0.20% | New | 600,000 | $16.3M |
| Vanguard Capital Management LLC | 0.00% | New | 463,385 | $12.6M |
| Farallon Capital Management, L.L.C. | 0.07% | New | 462,900 | $12.5M |
| Wellington Management Group LLP | 0.00% | New | 457,974 | $12.4M |
| Emerald Mutual Fund Advisers Trust | 0.40% | New | 422,127 | $11.4M |
| Ameriprise Financial Inc. | 0.00% | New | 418,965 | $11.3M |
| Geode Capital Management, LLC | 0.00% | New | 330,134 | $8.9M |
| Woodline Partners LP | 0.02% | New | 243,320 | $6.6M |
| New York State Common Retirement Fund | 0.01% | New | 200,758 | $5.4M |
| Citadel Advisors | 0.00% | New | 180,000 | $4.9M |
| Lord, Abbett & Co. LLC | 0.01% | New | 177,552 | $4.8M |
| LMR Partners LLP | 0.04% | New | 175,000 | $4.7M |
| Goldman Sachs Group Inc. | 0.00% | New | 160,029 | $4.3M |
| Seven Grand Managers, LLC | 0.16% | New | 150,000 | $4.1M |
| Ghisallo Capital Management LLC | 0.10% | New | 150,000 | $4.1M |
| State Street Corp. | 0.00% | New | 145,059 | $3.9M |
| Charles Schwab Investment Management Inc. | 0.00% | New | 114,956 | $3.1M |
| Alyeska Investment Group, L.P. | 0.01% | New | 113,396 | $3.1M |
| Avidity Partners Management LP | 0.48% | New | 110,000 | $3.0M |
| ExodusPoint Capital Management, LP | 0.03% | New | 100,691 | $2.7M |
| Northern Trust Corp. | 0.00% | New | 100,120 | $2.7M |
| Burkehill Global Management, LP | 0.10% | New | 100,000 | $2.7M |
| JPMorgan Chase & Co. | 0.00% | New | 92,665 | $2.6M |
| Vanguard Portfolio Management LLC | 0.00% | New | 91,085 | $2.5M |
| UBS Group AG | 0.00% | New | 86,751 | $2.4M |
| Vanguard Fiduciary Trust Co. | 0.00% | New | 82,282 | $2.2M |
| Soros Fund Management | 0.03% | New | 60,000 | $1.6M |
| Freestone Grove Partners LP | 0.01% | New | 60,000 | $1.6M |
| Ieq Capital, LLC | 0.01% | New | 58,795 | $1.6M |
| Sumitomo Mitsui Trust Group, Inc. | 0.00% | New | 56,452 | $1.5M |
| Amova Asset Management Americas, Inc. | 0.02% | New | 55,800 | $1.5M |
| Bellevue Group AG | 0.03% | New | 55,738 | $1.5M |
| Point72 Asset Management | 0.00% | New | 51,800 | $1.4M |
| Shay Capital LLC | 0.12% | New | 40,000 | $1.1M |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 0.06% | New | 34,742 | $941K |
| Bank of New York Mellon Corp | 0.00% | New | 32,514 | $881K |
| TD Asset Management Inc | 0.00% | New | 26,742 | $724K |
| Weiss Asset Management LP | 0.01% | New | 25,000 | $677K |
| Nuveen, LLC | 0.00% | New | 24,528 | $664K |
| XTX Topco Ltd | 0.01% | New | 21,048 | $570K |
| D. E. Shaw & Co. | 0.00% | New | 20,064 | $544K |
| Dymon Asia Capital (singapore) Pte. LTD. | 0.07% | New | 16,600 | $450K |
| Morgan Stanley | 0.00% | New | 15,166 | $411K |
| Palumbo Wealth Management LLC | 0.08% | New | 14,532 | $394K |
| Rhumbline Advisers | 0.00% | New | 14,151 | $383K |
| Deutsche Bank AG | 0.00% | New | 13,153 | $356K |
| Fred Alger Management, LLC | 0.00% | New | 13,089 | $355K |
| Oxford Asset Management LLP | 0.17% | New | 12,420 | $336K |
| Wells Fargo & Company | 0.00% | New | 11,818 | $320K |
| T. Rowe Price Associates Inc. | 0.00% | New | 11,065 | $300K |
| Squarepoint Ops LLC | 0.00% | New | 10,460 | $283K |
| Sei Investments Co. | 0.00% | New | 9,269 | $251K |
| Militia Capital Management LLC | 0.04% | New | 9,100 | $247K |
| MetLife Investment Management, LLC | 0.00% | New | 8,170 | $221K |
| Bank of America Corp. | 0.00% | New | 7,662 | $208K |
| Susquehanna International Group, LLP | 0.00% | New | 7,499 | $203K |
| Citigroup Inc. | 0.00% | New | 6,211 | $168K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | New | 6,097 | $165K |
| Vanguard Global Advisers, LLC | 0.00% | New | 5,541 | $150K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | New | 3,922 | $106K |
| US Bancorp \de | 0.00% | New | 3,853 | $104K |
| Barclays PLC | 0.00% | New | 3,187 | $86K |
| STRS Ohio | 0.00% | New | 2,600 | $70K |
| BNP Paribas Financial Markets | 0.00% | New | 2,031 | $55K |
| Legal & General Group Plc | 0.00% | New | 1,292 | $35K |
| Ameritas Investment Partners, Inc. | 0.00% | New | 1,207 | $33K |
| Russell Investments Group, Ltd. | 0.00% | New | 1,063 | $29K |
| Royal Bank of Canada | 0.00% | New | 591 | $16K |
| NewEdge Advisors, LLC | 0.00% | New | 440 | $12K |
| Tower Research Capital LLC (TRC) | 0.00% | New | 248 | $7K |
| California State Teachers Retirement System | 0.00% | New | 183 | $5K |
| Sterling Capital Management LLC | 0.00% | New | 115 | $3K |
| North Star Investment Management Corp. | 0.00% | New | 100 | $3K |
| SBI Securities Co., Ltd. | 0.00% | New | 2 | $54 |