Acorn Capital Advisors, LLC

In its 13F for Q1 2025 (holdings as of March 31, 2025, filed May 19, 2025), Acorn Capital Advisors, LLC reported 22 stock positions worth $149.9 million. Its top holding was CG Oncology (CGON) at 18.5% of the portfolio, followed by Urogen Pharma (URGN, 11.2%) and Y-Mabs Therapeutics (YMAB, 9.6%). Compared with Q4 2024, it opened 1 new position, added to 7 and reduced 2. The biggest buy was Trevi Therapeutics (TRVI, shares +7%) and the biggest sale Mural Oncology (MURA, shares −1%).

Most Recent 13F
Q2 2026
Location
NEW YORK, NY
CIK
0002054410
Portfolio Value
$149.9M (Q1 2025)
SEC Filing
0001636587-25-000021 ↗ filed May 19, 2025

Holdings Value

0$100.0M$200.0M$300.0M$400.0M Q4 2024: $185.8M Q4 2024 Q1 2025: $149.9M $149.9M Q1 2025 Q2 2025: $152.9M Q2 2025 Q3 2025: $197.0M Q3 2025 Q4 2025: $295.1M Q4 2025 Q1 2026: $351.8M Q1 2026 Q2 2026: $366.5M Q2 2026

Holdings 22 stocks · $149.9M

CGON CG Oncology Inc. 18.49% 1,131,501 $27.7M No change
URGN Urogen Pharma Ltd. 11.18% 1,516,303 $16.8M No change
YMAB Y-Mabs Therapeutics Inc. 9.56% 3,235,387 $14.3M Add +13.1%
TRVI Trevi Therapeutics Inc. 9.00% 2,144,844 $13.5M Add +7.2%
CADL Candel Therapeutics Inc. 8.11% 2,152,252 $12.2M Add +11.0%
PBYI Puma Biotechnology Inc. 7.78% 3,940,052 $11.7M No change
BCAX Bicara Therapeutics Inc. 5.59% 643,382 $8.4M Add +0.0%
TARA Protara Therapeutic Inc. 3.64% 1,279,800 $5.5M No change
TERN Terns Pharmaceuticals Inc. 3.63% 1,971,264 $5.4M No change
OKUR Onkure Therapeutics Inc. Class A 3.42% 1,439,674 $5.1M No change
VSTM Verastem Inc. 3.13% 779,498 $4.7M No change
HELP Cybin Inc. 3.11% 734,394 $4.7M Add +0.0%
CRDF Cardiff Oncology Inc. 3.02% 1,442,308 $4.5M No change
OPTINOSE INC 2.59% 422,814 $3.9M Add +0.0%
WHWK Whitehawk Therapeutics Inc. 1.35% 1,139,363 $2.0M Reduce -0.7%
XFOR X4 Pharmaceuticals Inc. 1.17% 7,310,650 $1.8M No change
MURA Mural Oncology PLC 1.07% 1,269,715 $1.6M Reduce -1.3%
AURA Aura Biosciences Inc. 0.97% 590,508 $1.5M New
BCAB Bioatla Inc. 0.94% 4,032,046 $1.4M No change
QTTB Q32 Bio Inc. 0.88% 803,425 $1.3M No change
VYNE THERAPEUTICS INC 0.83% 785,938 $1.2M Add +72.0%
ACRV Acrivon Therapeutics Inc. 0.55% 405,237 $823K No change

Portfolio Sells Q4 2024 → Q1 2025

MURA Mural Oncology PLC Reduce -1.3% 1.07% −1.16
WHWK Whitehawk Therapeutics Inc. Reduce -0.7% 1.35% −0.59

Portfolio Buys Q4 2024 → Q1 2025

TRVI Trevi Therapeutics Inc. Add +7.2% 9.00% +4.56
OPTINOSE INC Add +0.0% 2.59% +1.07
AURA Aura Biosciences Inc. New 0.97% +0.97
VYNE THERAPEUTICS INC Add +72.0% 0.83% +0.00
HELP Cybin Inc. Add +0.0% 3.11% −0.38
BCAX Bicara Therapeutics Inc. Add +0.0% 5.59% −0.44
CADL Candel Therapeutics Inc. Add +11.0% 8.11% −0.95
YMAB Y-Mabs Therapeutics Inc. Add +13.1% 9.56% −2.50

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 20$366.5MCGON, URGN, TRVI, CADL, PBYI
Q1 2026 22$351.8MTERN, CGON, URGN, PBYI, TRVI
Q4 2025 21$295.1MTERN, CGON, URGN, TRVI, PBYI
Q3 2025 20$197.0MCGON, URGN, PBYI, TRVI, TERN
Q2 2025 21$152.9MCGON, URGN, YMAB, PBYI, CADL
Q1 2025Amended 22$149.9MCGON, URGN, YMAB, TRVI, CADL
Q4 2024Amended 21$185.8MCGON, YMAB, CADL, URGN, PBYI