Adage Capital Partners Gp, L.L.C.

In its 13F for Q1 2025 (holdings as of March 31, 2025, filed May 15, 2025), Adage Capital Partners Gp, L.L.C. reported 820 stock positions worth $54.0 billion. Its top holding was Apple (AAPL) at 5.6% of the portfolio, followed by Microsoft (MSFT, 4.7%) and Nvidia (NVDA, 4.5%). Compared with Q4 2024, it opened 113 new positions, sold out of 145, added to 314 and reduced 358. The biggest buy was Soleno Therapeutics (SLNO, shares +58%) and the biggest sale Nvidia (NVDA, shares −2%).

Most Recent 13F
Q2 2026
Location
Boston, MA
CIK
0001165408
Portfolio Value
$54.0B (Q1 2025)
SEC Filing
0001172661-25-002042 ↗ filed May 15, 2025

Holdings Value

0$20.0B$40.0B$60.0B$80.0B Q1 2024: $52.9B Q1 2024 Q2 2024: $54.0B Q2 2024 Q3 2024: $56.6B Q3 2024 Q4 2024: $57.2B Q4 2024 Q1 2025: $54.0B $54.0B Q1 2025 Q2 2025: $59.3B Q2 2025 Q3 2025: $63.1B Q3 2025 Q4 2025: $66.0B Q4 2025 Q1 2026: $64.7B Q1 2026 Q2 2026: $71.3B Q2 2026

Holdings 820 stocks · $54.0B

AAPL Apple Inc. 5.60% 13,609,179 $3.0B Reduce -2.2%
MSFT Microsoft Corp. 4.71% 6,772,243 $2.5B Reduce -4.4%
NVDA Nvidia Corp. 4.52% 22,488,110 $2.4B Reduce -2.5%
HES Hess Corp. 3.05% 10,297,068 $1.6B Reduce -10.0%
AMZN Amazon.com Inc. 3.00% 8,511,360 $1.6B Reduce -4.5%
META Meta Platforms Inc. Class A 2.28% 2,132,035 $1.2B Add +2.1%
BRK.B Berkshire Hathaway Inc. Class B 1.57% 1,587,569 $845.5M Reduce -13.4%
GOOGL Alphabet Inc. Class A 1.52% 5,289,300 $817.9M Reduce -2.8%
AVGO Broadcom Inc. 1.26% 4,071,060 $681.6M Reduce -4.2%
GOOG Alphabet Inc. Class C 1.23% 4,236,120 $661.8M Reduce -3.2%
TSLA Tesla Inc. 1.22% 2,532,600 $656.3M Reduce -2.0%
JPM JPMorgan Chase & Co. 1.15% 2,519,866 $618.1M Reduce -3.6%
LLY Eli Lilly & Co. 1.14% 741,722 $612.6M Add +1.3%
V Visa Inc. Class A 1.09% 1,683,340 $589.9M Reduce -2.5%
XOM Exxon Mobil Corp. 0.89% 4,055,165 $482.3M Reduce -9.8%
UNH Unitedhealth Group Inc. 0.89% 914,051 $478.7M Add +0.3%
HD Home Depot Inc. 0.83% 1,217,756 $446.3M Add +19.5%
PG The Procter & Gamble Co. 0.77% 2,427,206 $413.6M Add +7.0%
COP Conocophillips 0.75% 3,867,454 $406.2M Reduce -10.4%
MA Mastercard Inc. Class A 0.73% 721,710 $395.6M Reduce -3.3%
DOV Dover Corp. 0.70% 2,148,626 $377.5M Reduce -1.6%
ABBV Abbvie Inc. 0.70% 1,798,733 $376.9M Add +4.0%
COST Costco Wholesale Corp. 0.67% 382,277 $361.5M Reduce -1.3%
NFLX Netflix Inc. 0.66% 382,633 $356.8M Reduce -1.8%
WMT Walmart Inc. 0.65% 3,993,226 $350.6M Add +0.4%
HUBB Hubbell Inc. 0.60% 975,196 $322.7M Add +181.6%
SLNO Soleno Therapeutics Inc. 0.58% 4,392,696 $313.9M Add +58.2%
BAC Bank of America Corp. filed as BANK AMERICA CORP 0.52% 6,738,273 $281.2M Add +9.7%
CSCO Cisco Systems Inc. 0.51% 4,429,021 $273.3M Add +8.8%
INSM Insmed Inc. 0.49% 3,446,944 $263.0M Add +109.2%
BSX Boston Scientific Corp. 0.48% 2,592,113 $261.5M Reduce -1.1%
MMM 3M Co. 0.46% 1,707,198 $250.7M Add +16.6%
ORCL Oracle Corp. 0.46% 1,779,416 $248.8M Add +22.9%
VRTX Vertex Pharmaceuticals Inc. 0.44% 489,667 $237.4M Add +134.0%
WM Waste Management Inc. 0.43% 999,667 $231.4M Add +4.9%
PM Philip Morris International 0.42% 1,417,954 $225.1M Reduce -2.5%
CRM Salesforce Inc. 0.41% 832,739 $223.5M Reduce -3.6%
IBM Intl Business Machines Corp. filed as INTERNATIONAL BUSINESS MACHS 0.41% 893,190 $222.1M Reduce -4.4%
KO The Coca-Cola Co. 0.41% 3,085,282 $221.0M Reduce -21.9%
JNJ Johnson & Johnson 0.39% 1,278,427 $212.0M Add +36.8%
DIS The Walt Disney Co. filed as DISNEY WALT CO 0.39% 2,123,625 $209.6M Add +15.2%
INTU Intuit Inc. 0.38% 337,800 $207.4M Add +38.4%
MCD McDonald's Corp. 0.38% 653,502 $204.1M Reduce -49.2%
T AT&T Inc. 0.38% 7,216,039 $204.1M Reduce -11.6%
WFC Wells Fargo & Co. 0.38% 2,832,096 $203.3M Reduce -7.1%
LIN Linde PLC 0.37% 434,235 $202.2M Reduce -2.5%
RTX RTX Corp. 0.37% 1,522,749 $201.7M Add +36.0%
DHR Danaher Corp. 0.37% 981,426 $201.2M Add +124.4%
RPRX Royalty Pharma PLC Class A 0.36% 6,250,000 $194.6M Reduce -63.2%
ISRG Intuitive Surgical Inc. 0.35% 386,487 $191.4M Reduce -6.1%
ABT Abbott Laboratories 0.35% 1,417,664 $188.1M Add +23.2%
NSC Norfolk Southern Corp. 0.35% 789,950 $187.1M Add +341.9%
PEP Pepsico Inc. 0.34% 1,235,679 $185.3M Reduce -1.0%
VZ Verizon Communications Inc. 0.34% 4,025,697 $182.6M Reduce -6.1%
MRK Merck & Co. Inc. 0.34% 2,026,500 $181.9M Add +35.5%
SCHW Schwab (charles) Corp. 0.32% 2,184,039 $171.0M Add +56.3%
ACN Accenture PLC Class A 0.31% 540,422 $168.6M Reduce -4.0%
DFS Discover Financial Services 0.30% 955,670 $163.1M Add +93.3%
ADBE Adobe Inc. 0.30% 421,978 $161.8M Reduce -15.0%
LOW Lowe's Cos Inc. 0.30% 688,305 $160.5M Add +6.9%
GE General Electric filed as GE AEROSPACE 0.30% 797,483 $159.6M Reduce -15.9%
PLTR Palantir Technologies Inc. Class A 0.29% 1,869,300 $157.8M Reduce -2.5%
FYBR Frontier Communications Pare 0.29% 4,378,238 $157.0M Add +39.0%
BKNG Booking Holdings Inc. 0.29% 33,700 $155.3M Add +9.1%
MDT Medtronic PLC 0.29% 1,726,158 $155.1M Add +4.3%
QCOM Qualcomm Inc. 0.28% 988,621 $151.9M Reduce -4.8%
CB Chubb Ltd. 0.27% 489,883 $147.9M Add +88.2%
GILD Gilead Sciences Inc. 0.27% 1,320,152 $147.9M Reduce -23.0%
GS Goldman Sachs Group Inc. 0.27% 269,509 $147.2M Reduce -5.6%
MCK McKesson Corp. 0.27% 218,130 $146.8M Add +14.2%
BA The Boeing Co. 0.27% 838,222 $143.0M Add +36.2%
PGR Progressive Corp. 0.26% 501,180 $141.8M Reduce -8.5%
SPGI S&P Global Inc. 0.26% 276,220 $140.3M Reduce -0.7%
AMD Advanced Micro Devices 0.26% 1,347,794 $138.5M Reduce -4.4%
DUK Duke Energy Corp. 0.26% 1,132,613 $138.1M Add +359.1%
ROST Ross Stores Inc. 0.26% 1,080,532 $138.1M Add +184.4%
EQIX Equinix Inc. 0.26% 168,768 $137.6M Add +1.0%
NOW ServiceNow Inc. 0.25% 168,900 $134.5M Reduce -10.0%
ANSS Ansys Inc. 0.25% 424,276 $134.3M Add +44.5%
WCC Wesco International Inc. 0.25% 855,035 $132.8M Reduce -37.4%
RCL Royal Caribbean Cruises Ltd. 0.25% 645,200 $132.5M Add +179.2%
ADP Automatic Data Processing 0.24% 421,076 $128.7M Reduce -13.3%
LBRDK Liberty Broadband-C 0.24% 1,491,606 $126.9M Add +21.2%
MS Morgan Stanley 0.23% 1,078,434 $125.8M Reduce -6.1%
TXN Texas Instruments Inc. 0.23% 694,544 $124.8M Reduce -6.0%
VMC Vulcan Materials Co. 0.23% 533,498 $124.5M Add +62.5%
AXP American Express Co. 0.23% 462,588 $124.5M Reduce -5.3%
STR Sitio Royalties Corp. Class A 0.23% 6,259,058 $124.4M Reduce -0.1%
SO The Southern Co. 0.23% 1,349,200 $124.1M Add +125.3%
C Citigroup Inc. 0.23% 1,716,786 $121.9M Reduce -15.2%
ICE Intercontinental Exchange Inc. 0.22% 693,959 $119.7M Add +31.8%
CMCSA Comcast Corp. Class A 0.22% 3,239,459 $119.5M Reduce -6.6%
BMY Bristol-Myers Squibb Co. 0.22% 1,952,268 $119.1M Reduce -74.9%
TMO Thermo Fisher Scientific Inc. 0.22% 233,452 $116.2M Reduce -40.2%
AMAT Applied Materials Inc. 0.21% 798,126 $115.8M Reduce -3.3%
SWX Southwest Gas Holdings Inc. 0.21% 1,550,000 $111.3M Add +72.2%
AZO AutoZone Inc. 0.20% 28,648 $109.2M Reduce -24.7%
FISV Fiserv Inc. 0.20% 483,831 $106.8M Reduce -4.9%
TMUS T-Mobile US Inc. 0.20% 397,334 $106.0M Reduce -12.8%
HIG Hartford Insurance Group Inc. 0.20% 852,432 $105.5M Add +81.0%

Show all 820 holdings

Options reported separately and not counted above: HUM calls ($19.6M).

Other holdings (16): bonds, preferreds, convertibles and warrants · $14.6M (not counted above)
SecurityClassShares / PrincipalValueChange
KOSMOS ENERGY LTD (KOS 3.125 03/15/30) NOTE 3.125% 3/1 · principal 17,500,000$13.3MNew
LZM.WS Lifezone Metals Ltd. -28 *W EXP 07/05/202 1,231,797$567KNo change
DYNCW Dynamix Corp. - 29 *W EXP 10/25/202 675,000$193KNew
PDYNW Sarcos Technology -CW27 *W EXP 09/24/202 427,763$120KNo change
NUVB.WS Nuvation Bio Inc. -CW27 *W EXP 02/10/202 266,666$85KNo change
ASBPW Aspire Biopharma Holdin-CW27 *W EXP 02/14/203 1,050,000$71KNew
CLSKW Cleanspark Inc.-29 *W EXP 12/29/202 261,080$46KNo change
ZEOWW Esgen Acquisition A -CW23 *W EXP 03/13/202 760,000$43KNo change
BDMDW Baird Medical Investment -28 *W EXP 10/01/202 375,000$28KNo change
BRLSW Oxus Acquisition Corp. -CW23 *W EXP 02/07/202 235,753$26KNo change
RVMDW Revolution Medicines Inc.-28 *W EXP 12/17/202 500,000$19KNo change
BAERW Wildfire New Pubco Inc.-27 *W EXP 01/24/202 183,333$10KNo change
ZAPWF Zapp Electric Vehicles -28 *W EXP 99/99/999 897,838$8KNo change
LANWF Lanvin Group Holdings Ltd.-27 *W EXP 01/14/202 64,733$1KNo change
IVAWF Investcorp India Acquisi -27 *W EXP 06/01/202 1,012,500$1KNo change
SKGRW SK Growth Opportunities -29 *W EXP 06/28/202 300,000$300No change

Total filed on the 13F, all lines: $54.0B.

Portfolio Sells Q4 2024 → Q1 2025

NVDA Nvidia Corp. Reduce -2.5% 4.52% −0.90
TSLA Tesla Inc. Reduce -2.0% 1.22% −0.61
BMY Bristol-Myers Squibb Co. Reduce -74.9% 0.22% −0.55
MSFT Microsoft Corp. Reduce -4.4% 4.71% −0.51
AAPL Apple Inc. Reduce -2.2% 5.60% −0.49
AVGO Broadcom Inc. Reduce -4.2% 1.26% −0.46
AMZN Amazon.com Inc. Reduce -4.5% 3.00% −0.42
RPRX Royalty Pharma PLC Class A Reduce -63.2% 0.36% −0.40
UNP Union Pacific Corp. Reduce -96.7% 0.01% −0.32
GOOGL Alphabet Inc. Class A Reduce -2.8% 1.52% −0.29
MCD McDonald's Corp. Reduce -49.2% 0.38% −0.27
DAL Delta Air Lines Inc. Reduce -78.9% 0.05% −0.27
GOOG Alphabet Inc. Class C Reduce -3.2% 1.23% −0.23
SHW The Sherwin-Williams Co. Reduce -72.6% 0.09% −0.22
PCG P G & E Corp. Reduce -63.7% 0.10% −0.21
WCC Wesco International Inc. Reduce -37.4% 0.25% −0.19
SRE Sempra Reduce -80.7% 0.03% −0.17
TMO Thermo Fisher Scientific Inc. Reduce -40.2% 0.22% −0.14
GERN Geron Corp. Sold out 0.00% −0.14
PH Parker Hannifin Corp. Reduce -49.5% 0.13% −0.13
SUM Summit Materials Inc. Class A Sold out 0.00% −0.12
SOC Sable Offshore Corp. Reduce -89.7% 0.02% −0.11
NOC Northrop Grumman Corp. Reduce -84.1% 0.02% −0.11
LDOS Leidos Holdings Inc. Sold out 0.00% −0.11
ALK Alaska Air Group Inc. Sold out 0.00% −0.11
UAL United Airlines Holdings Inc. Reduce -64.8% 0.04% −0.11
ETN Eaton Corp. PLC Reduce -31.2% 0.16% −0.11
ROP Roper Technologies Inc. Sold out 0.00% −0.11
HCP Hashicorp Inc. Class A Sold out 0.00% −0.10
NOW ServiceNow Inc. Reduce -10.0% 0.25% −0.10
EW Edwards Lifesciences Corp. Reduce -63.0% 0.06% −0.10
AN Autonation Inc. Reduce -56.5% 0.07% −0.10
PEG Public Service Enterprise GP Sold out 0.00% −0.09
FTV Fortive Corp. Reduce -77.1% 0.03% −0.09
CRM Salesforce Inc. Reduce -3.6% 0.41% −0.09
ULTA Ulta Beauty Inc. Reduce -72.9% 0.03% −0.09
AIG American International Group Reduce -86.5% 0.02% −0.09
ADBE Adobe Inc. Reduce -15.0% 0.30% −0.09
JCI Johnson Controls Internation Reduce -52.5% 0.09% −0.09
IR Ingersoll-Rand Inc. Reduce -53.8% 0.06% −0.08
DYN Dyne Therapeutics Inc. Sold out 0.00% −0.08
FBIN Fortune Brands Innovations I Reduce -67.5% 0.04% −0.08
AWI Armstrong World Industries Reduce -50.0% 0.09% −0.08
ALTM Arcadium Lithium PLC Sold out 0.00% −0.07
DXCM Dexcom Inc. Reduce -97.3% 0.00% −0.07
ARES Ares Management Corp. Class A Sold out 0.00% −0.07
CMI Cummins Inc. Reduce -86.5% 0.01% −0.07
GM General Motors Co. Reduce -67.6% 0.03% −0.07
SPR Spirit Aerosystems Hold Class A Reduce -48.6% 0.08% −0.07
XYL Xylem Inc. Sold out 0.00% −0.06

Portfolio Buys Q4 2024 → Q1 2025

SLNO Soleno Therapeutics Inc. Add +58.2% 0.58% +0.36
HUBB Hubbell Inc. Add +181.6% 0.60% +0.34
VRTX Vertex Pharmaceuticals Inc. Add +134.0% 0.44% +0.29
INSM Insmed Inc. Add +109.2% 0.49% +0.29
NSC Norfolk Southern Corp. Add +341.9% 0.35% +0.27
DUK Duke Energy Corp. Add +359.1% 0.26% +0.21
DHR Danaher Corp. Add +124.4% 0.37% +0.20
VRNA Verona Pharma Ltd. Add +381.9% 0.19% +0.16
ABBV Abbvie Inc. Add +4.0% 0.70% +0.16
JNJ Johnson & Johnson Add +36.8% 0.39% +0.16
ROST Ross Stores Inc. Add +184.4% 0.26% +0.16
DFS Discover Financial Services Add +93.3% 0.30% +0.15
RCL Royal Caribbean Cruises Ltd. Add +179.2% 0.25% +0.15
CB Chubb Ltd. Add +88.2% 0.27% +0.15
RTX RTX Corp. Add +36.0% 0.37% +0.15
LLY Eli Lilly & Co. Add +1.3% 1.14% +0.15
FANG Diamondback Energy Inc. New 0.14% +0.14
SO The Southern Co. Add +125.3% 0.23% +0.14
LMT Lockheed Martin Corp. Add +424.7% 0.18% +0.14
META Meta Platforms Inc. Class A Add +2.1% 2.28% +0.14
SCHW Schwab (charles) Corp. Add +56.3% 0.32% +0.14
MMM 3M Co. Add +16.6% 0.46% +0.13
HD Home Depot Inc. Add +19.5% 0.83% +0.13
ABT Abbott Laboratories Add +23.2% 0.35% +0.12
INTU Intuit Inc. Add +38.4% 0.38% +0.12
TDG Transdigm Group Inc. New 0.11% +0.11
ETR Entergy Corp. Add +123.0% 0.18% +0.11
MDGL Madrigal Pharmaceuticals Inc. Add +860.0% 0.12% +0.11
HIG Hartford Insurance Group Inc. Add +81.0% 0.20% +0.11
DASH DoorDash Inc. Class A New 0.10% +0.10
ALNY Alnylam Pharmaceuticals Inc. Add +203.2% 0.14% +0.10
PG The Procter & Gamble Co. Add +7.0% 0.77% +0.10
FYBR Frontier Communications Pare Add +39.0% 0.29% +0.10
WY Weyerhaeuser Co. New 0.10% +0.10
SWX Southwest Gas Holdings Inc. Add +72.2% 0.21% +0.10
ASND Ascendis Pharma A/S New 0.09% +0.09
MTDR Matador Resources Co. Add +2002.9% 0.10% +0.09
TAK Takeda Pharmaceutic-SP ADR New 0.09% +0.09
WM Waste Management Inc. Add +4.9% 0.43% +0.09
CSCO Cisco Systems Inc. Add +8.8% 0.51% +0.09
ICE Intercontinental Exchange Inc. Add +31.8% 0.22% +0.08
VMC Vulcan Materials Co. Add +62.5% 0.23% +0.08
MCK McKesson Corp. Add +14.2% 0.27% +0.08
MDLZ Mondelez International Inc. Class A Add +48.0% 0.19% +0.08
UNH Unitedhealth Group Inc. Add +0.3% 0.89% +0.08
EXR Extra Space Storage Inc. Add +215.0% 0.11% +0.08
MRK Merck & Co. Inc. Add +35.5% 0.34% +0.08
CACI Caci International Inc. Class A Add +7415.0% 0.08% +0.08
ANSS Ansys Inc. Add +44.5% 0.25% +0.08
BA The Boeing Co. Add +36.2% 0.27% +0.07

Options Activity Q4 2024 → Q1 2025

HUM Humana Inc. call New 74,100 $19.6M

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

Notes & Other Activity Q4 2024 → Q1 2025

KOSMOS ENERGY LTD (KOS 3.125 03/15/30) NOTE 3.125% 3/1 · principal New 17,500,000 $13.3M
DYNCW Dynamix Corp. - 29 *W EXP 10/25/202 New 675,000 $193K
NPWR.WS Rice Acquisition Corp. II-CW *W EXP 06/08/202 Sold out 20,000 $72Kbefore exit
ASBPW Aspire Biopharma Holdin-CW27 *W EXP 02/14/203 New 1,050,000 $71K
NKGNW Graf Acquisition Corp.-CW28 *W EXP 05/31/202 Sold out 159,266 $16Kbefore exit
ASBPW Aspire Biopharma Holdin-CW27 *W EXP 05/23/202 Sold out 1,050,000 $1Kbefore exit
CRTWF Cartica Acquisition A -28 *W EXP 04/30/202 Sold out 200,000 $200before exit

Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 915$71.3BNVDA, AAPL, MSFT, AMZN, GOOGL
Q1 2026 889$64.7BNVDA, AAPL, MSFT, AMZN, GOOGL
Q4 2025 872$66.0BNVDA, AAPL, MSFT, AMZN, GOOGL
Q3 2025 856$63.1BNVDA, MSFT, AAPL, AMZN, META
Q2 2025 828$59.3BNVDA, MSFT, AAPL, AMZN, META
Q1 2025 820$54.0BAAPL, MSFT, NVDA, HES, AMZN
Q4 2024 852$57.2BAAPL, NVDA, MSFT, AMZN, HES
Q3 2024 833$56.6BAAPL, MSFT, NVDA, AMZN, HES
Q2 2024 824$54.0BMSFT, NVDA, AAPL, AMZN, HES
Q1 2024 815$52.9BMSFT, AAPL, NVDA, AMZN, META