Caligan Partners LP

In its 13F for Q3 2024 (holdings as of September 30, 2024, filed November 14, 2024), Caligan Partners LP reported 12 stock positions worth $315.5 million. Its top holding was Liquidia (LQDA) at 25.7% of the portfolio, followed by Verona Pharma (VRNA, 13.1%) and Exelixis (EXEL, 12.6%). Compared with Q2 2024, it sold out of 1, added to 5 and reduced 6. The biggest buy was Evolus (EOLS, shares +1%) and the biggest sale an exit from Alimera Sciences (ALIM).

Most Recent 13F
Q2 2026
Location
NEW YORK, NY
CIK
0001727492
Portfolio Value
$315.5M (Q3 2024)
SEC Filing
0001420506-24-002574 ↗ filed Nov 14, 2024

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q1 2024: $378.3M Q1 2024 Q2 2024: $428.0M Q2 2024 Q3 2024: $315.5M $315.5M Q3 2024 Q4 2024: $394.9M Q4 2024 Q1 2025: $479.2M Q1 2025 Q2 2025: $515.1M Q2 2025 Q3 2025: $720.7M Q3 2025 Q4 2025: $1.1B Q4 2025 Q1 2026: $1.4B Q1 2026 Q2 2026: $2.1B Q2 2026

Holdings 12 stocks · $315.5M

LQDA Liquidia Corp. 25.73% 8,118,592 $81.2M Reduce -21.6%
VRNA Verona Pharma Ltd. 13.10% 1,436,878 $41.3M Reduce -22.1%
EXEL Exelixis Inc. 12.55% 1,525,730 $39.6M No change
EOLS Evolus Inc. 11.26% 2,193,488 $35.5M Add +1.2%
ANIK Anika Therapeutics Inc. 11.24% 1,435,130 $35.4M Reduce -0.1%
AGIO Agios Pharmaceuticals Inc. 8.16% 579,717 $25.8M Add +12.6%
BCRX Biocryst Pharmaceuticals Inc. 6.22% 2,583,585 $19.6M Reduce -43.8%
YMAB Y-Mabs Therapeutics Inc. 4.98% 1,195,253 $15.7M Add +105.3%
MLYS Mineralys Therapeutics Inc. 3.77% 981,155 $11.9M Add +31.6%
NBP Novabridge Biosciences filed as I MAB 1.38% 3,499,330 $4.3M Add +3.7%
ENTA Enanta Pharmaceuticals Inc. 1.06% 322,453 $3.3M Reduce -69.1%
OTLK Outlook Therapeutics Inc. 0.54% 318,699 $1.7M Reduce -36.3%

Portfolio Sells Q2 2024 → Q3 2024

ALIM Alimera Sciences Inc. Sold out 0.00% −21.87
LQDA Liquidia Corp. Reduce -21.6% 25.73% −3.31
ENTA Enanta Pharmaceuticals Inc. Reduce -69.1% 1.06% −2.10
BCRX Biocryst Pharmaceuticals Inc. Reduce -43.8% 6.22% −0.42
OTLK Outlook Therapeutics Inc. Reduce -36.3% 0.54% −0.32
ANIK Anika Therapeutics Inc. Reduce -0.1% 11.24% +2.74
VRNA Verona Pharma Ltd. Reduce -22.1% 13.10% +6.87

Portfolio Buys Q2 2024 → Q3 2024

EOLS Evolus Inc. Add +1.2% 11.26% +5.77
YMAB Y-Mabs Therapeutics Inc. Add +105.3% 4.98% +3.34
AGIO Agios Pharmaceuticals Inc. Add +12.6% 8.16% +2.98
MLYS Mineralys Therapeutics Inc. Add +31.6% 3.77% +1.73
NBP Novabridge Biosciences Add +3.7% 1.38% +0.06

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 25$2.1BLQDA, RVMD, ABVX, PCVX, EXEL
Q1 2026 24$1.4BLQDA, ABVX, RVMD, PCVX, XENE
Q4 2025 20$1.1BLQDA, ABVX, RVMD, MLYS, PCVX
Q3 2025 16$720.7MLQDA, ABVX, MLYS, EXEL, RVMD
Q2 2025 16$515.1MVRNA, LQDA, EXEL, AGIO, MRUS
Q1 2025 16$479.2MLQDA, VRNA, EXEL, MLYS, EOLS
Q4 2024 14$394.9MLQDA, VRNA, EXEL, EOLS, ANIK
Q3 2024 12$315.5MLQDA, VRNA, EXEL, EOLS, ANIK
Q2 2024 13$428.0MLQDA, ALIM, ANIK, EXEL, BCRX
Q1 2024 12$378.3MLQDA, ALIM, ANIK, EOLS, EXEL