Gilead Sciences, Inc.

In its 13F for Q3 2025 (holdings as of September 30, 2025, filed November 13, 2025), Gilead Sciences, Inc. reported 9 stock positions worth $1.8 billion. Its top holding was Lakefront Biotherapeutic-ADR (LKFT) at 32.3% of the portfolio, followed by Arcellx (ACLX, 30.8%) and Arcus Biosciences (RCUS, 23.9%). Compared with Q2 2025, it sold out of 5 and added to 1. The biggest buy was Assembly Biosciences (ASMB, shares +104%) and the biggest sale an exit from Hookipa Pharma (HOOK).

Most Recent 13F
Q2 2026
Location
FOSTER CITY, CA
CIK
0000882095
Portfolio Value
$1.8B (Q3 2025)
SEC Filing
0001123292-25-000642 ↗ filed Nov 13, 2025

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q4 2024: $1.6B Q4 2024 Q1 2025: $1.2B Q1 2025 Q2 2025: $1.3B Q2 2025 Q3 2025: $1.8B $1.8B Q3 2025 Q4 2025: $1.9B Q4 2025 Q1 2026: $2.1B Q1 2026 Q2 2026: $1.6B Q2 2026

Holdings 9 stocks · $1.8B

LKFT Lakefront Biotherapeutic-ADR filed as GALAPAGOS NV 32.31% 16,707,477 $578.7M No change
ACLX Arcellx Inc. 30.80% 6,720,803 $551.8M No change
RCUS Arcus Biosciences Inc. 23.86% 31,424,760 $427.4M No change
ASMB Assembly Biosciences Inc. 6.44% 4,505,391 $115.3M Add +103.9%
MRUS Merus NV 2.38% 452,527 $42.6M No change
TNGX Tango Therapeutics Inc. 2.28% 4,854,443 $40.8M No change
KYTX Kyverna Therapeutics Inc. 1.38% 4,126,119 $24.8M No change
XLO Xilio Therapeutics Inc. 0.43% 9,105,451 $7.7M No change
CYPH Cypherpunk Technologies Inc. filed as LEAP THERAPEUTICS INC 0.13% 5,319,148 $2.4M No change

Portfolio Sells Q2 2025 → Q3 2025

HOOK Hookipa Pharma Inc. Sold out 0.00% −0.18
ALLO Allogene Therapeutics Inc. Sold out 0.00% −0.10
KLRS Kalaris Therapeutics Inc. Sold out 0.00% −0.07
IKENA ONCOLOGY INC Sold out 0.00% −0.04
BRNS Barinthus Biotherapeutics PL Sold out 0.00% −0.01

Portfolio Buys Q2 2025 → Q3 2025

ASMB Assembly Biosciences Inc. Add +103.9% 6.44% +3.31

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 5$1.6BRCUS, LKFT, ASMB, KYTX, XLO
Q1 2026 6$2.1BACLX, RCUS, LKFT, ASMB, KYTX
Q4 2025 6$1.9BRCUS, LKFT, ACLX, ASMB, KYTX
Q3 2025 9$1.8BLKFT, ACLX, RCUS, ASMB, MRUS
Q2 2025 14$1.3BLKFT, ACLX, RCUS, ASMB, TNGX
Q1 2025 14$1.2BACLX, LKFT, RCUS, ASMB, MRUS
Q4 2024 16$1.6BACLX, LKFT, RCUS, ASMB, MRUS