Madrone Advisors, LLC

In its 13F for Q2 2024 (holdings as of June 30, 2024, filed August 14, 2024), Madrone Advisors, LLC reported 6 stock positions worth $569.5 million. Its top holding was Stoneco Class A (STNE) at 53.3% of the portfolio, followed by Vanguard Tot World STK ETF (VT, 39.2%) and Pacific Biosciences of Calif (PACB, 5.6%). Compared with Q1 2024, it sold out of 1, added to 1 and reduced 2. The biggest buy was Pacific Biosciences of Calif (PACB, shares +33%) and the biggest sale an exit from Cue Health (HLTHQ).

Most Recent 13F
Q2 2026
Location
Denver, CO
CIK
0001964563
Portfolio Value
$569.5M (Q2 2024)
SEC Filing
0001104659-24-089645 ↗ filed Aug 14, 2024

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q1 2024: $729.9M Q1 2024 Q2 2024: $569.5M $569.5M Q2 2024 Q3 2024: $626.2M Q3 2024 Q4 2024: $524.8M Q4 2024 Q1 2025: $597.0M Q1 2025 Q2 2025: $719.6M Q2 2025 Q3 2025: $2.0B Q3 2025 Q4 2025: $1.6B Q4 2025 Q1 2026: $1.0B Q1 2026 Q2 2026: $1.4B Q2 2026

Holdings 6 stocks · $569.5M

STNE Stoneco Ltd. Class A 53.34% 25,339,276 $303.8M No change
VT Vanguard Tot World STK ETF 39.21% 1,982,655 $223.3M Reduce -4.4%
PACB Pacific Biosciences of Calif 5.63% 23,391,915 $32.0M Add +33.0%
ILMN Illumina Inc. 1.47% 80,000 $8.4M No change
OPRT Oportun Financial Corp. 0.32% 623,295 $1.8M No change
GRAL Grail Inc. 0.04% 13,333 $205K Reduce -0.2%

Portfolio Sells Q1 2024 → Q2 2024

HLTHQ Cue Health Inc. Sold out 0.00% −0.18
GRAL Grail Inc. Reduce -0.2% 0.04% +0.01
VT Vanguard Tot World STK ETF Reduce -4.4% 39.21% +7.80

Portfolio Buys Q1 2024 → Q2 2024

PACB Pacific Biosciences of Calif Add +33.0% 5.63% −3.41

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 6$1.4BSTUB, STNE, QXO, VT, COF
Q1 2026 5$1.0BSTUB, STNE, VT, QXO, FIG
Q4 2025 5$1.6BSTUB, STNE, QXO, VT, FIG
Q3 2025 6$2.0BSTUB, STNE, QXO, VT, FIG
Q2 2025 5$719.6MSTNE, QXO, VT, PACB, OPRT
Q1 2025 6$597.0MSTNE, QXO, VT, PACB, ILMN
Q4 2024 6$524.8MSTNE, QXO, VT, PACB, ILMN
Q3 2024 6$626.2MSTNE, QXO, VT, PACB, ILMN
Q2 2024 6$569.5MSTNE, VT, PACB, ILMN, OPRT
Q1 2024 6$729.9MSTNE, VT, PACB, ILMN, OPRT