Mass General Brigham, Inc

In its 13F for Q1 2024 (holdings as of March 31, 2024, filed April 4, 2024), Mass General Brigham, Inc reported 5 stock positions worth $57.1 million. Its top holding was Coinbase Global Class A (COIN) at 65.1% of the portfolio, followed by Revolution Medicines (RVMD, 19.1%) and Pliant Therapeutics (PLRX, 7.5%). Compared with Q4 2023, it opened 4 new positions, sold out of 1 and added to 1. The biggest buy was a new position in Revolution Medicines (RVMD) and the biggest sale an exit from Snowflake (SNOW).

Most Recent 13F
Q2 2026
Location
SOMERVILLE, MA
CIK
0001678378
Portfolio Value
$57.1M (Q1 2024)
SEC Filing
0001678378-24-000003 ↗ filed Apr 4, 2024

Holdings Value

0$200.0M$400.0M$600.0M$800.0M$1.0B Q1 2024: $57.1M $57.1M Q1 2024 Q2 2024: $20.5M Q2 2024 Q3 2024: $43.6M Q3 2024 Q4 2025: $809.8M Q4 2025 Q1 2026: $468.9M Q1 2026 Q2 2026: $361.1M Q2 2026

Holdings 5 stocks · $57.1M

COIN Coinbase Global Inc. Class A 65.08% 140,229 $37.2M Add +8.8%
RVMD Revolution Medicines Inc. 19.08% 338,191 $10.9M New
PLRX Pliant Therapeutics Inc. 7.53% 288,690 $4.3M New
TNGX Tango Therapeutics Inc. 4.92% 354,192 $2.8M New
FULC Fulcrum Therapeutics Inc. 3.39% 205,356 $1.9M New

Portfolio Sells Q4 2023 → Q1 2024

SNOW Snowflake Inc. Sold out 0.00% −19.95

Portfolio Buys Q4 2023 → Q1 2024

RVMD Revolution Medicines Inc. New 19.08% +19.08
PLRX Pliant Therapeutics Inc. New 7.53% +7.53
TNGX Tango Therapeutics Inc. New 4.92% +4.92
FULC Fulcrum Therapeutics Inc. New 3.39% +3.39
COIN Coinbase Global Inc. Class A Add +8.8% 65.08% −14.98

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 6$361.1MACWI, KRMN, RVMD, TNGX, MAZE
Q1 2026 6$468.9MACWI, KRMN, RVMD, TNGX, MAZE
Q4 2025 7$809.8MACWI, KRMN, RVMD, MAZE, TNGX
Q3 2024 5$43.6MIOT, RVMD, PLRX, TNGX, FULC
Q2 2024 4$20.5MRVMD, PLRX, TNGX, FULC
Q1 2024 5$57.1MCOIN, RVMD, PLRX, TNGX, FULC