New Leaf Venture Partners, L.L.C.
In its 13F for Q1 2025 (holdings as of March 31, 2025, filed May 13, 2025), New Leaf Venture Partners, L.L.C. reported 9 stock positions worth $44.9 million. Its top holding was Edgewise Therapeutics (EWTX) at 50.5% of the portfolio, followed by Arvinas (ARVN, 24.8%) and Crinetics Pharmaceuticals (CRNX, 10.5%). Its holdings were unchanged from Q4 2024.
- Most Recent 13F
- Q3 2025
- Location
- New York, NY
- CIK
- 0001631614
- Portfolio Value
- $44.9M (Q1 2025)
- SEC Filing
- 0000950123-25-004966 ↗ filed May 13, 2025
Holdings Value
Holdings 9 stocks · $44.9M
| EWTX Edgewise Therapeutics Inc. | 50.47% | 1,030,161 | $22.7M | No change |
| ARVN Arvinas Inc. | 24.79% | 1,585,721 | $11.1M | No change |
| CRNX Crinetics Pharmaceuticals Inc. | 10.53% | 141,000 | $4.7M | No change |
| RLYB Rallybio Corp. | 4.78% | 3,301,603 | $2.1M | No change |
| COGT Cogent Biosciences Inc. | 3.35% | 250,765 | $1.5M | No change |
| RCKT Rocket Pharmaceuticals Inc. | 2.24% | 150,706 | $1.0M | No change |
| PASG Passage Bio Inc. | 1.96% | 2,497,922 | $882K | No change |
| ITRMF Iterum Therapeutics PLC | 0.95% | 345,020 | $424K | No change |
| ALEC Alector Inc. | 0.93% | 339,569 | $418K | No change |
Portfolio Sells Q4 2024 → Q1 2025
| None this quarter. | |||
Portfolio Buys Q4 2024 → Q1 2025
| None this quarter. | |||
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q3 2025 | 7 | $43.0M | EWTX, ARVN, CRNX, COGT, RLYB |
| Q2 2025 | 8 | $52.9M | PASG, EWTX, ARVN, CRNX, COGT |
| Q1 2025 | 9 | $44.9M | EWTX, ARVN, CRNX, RLYB, COGT |
| Q4 2024 | 9 | $74.8M | ARVN, EWTX, CRNX, RLYB, COGT |
| Q3 2024 | 10 | $97.3M | EWTX, ARVN, CRNX, RLYB, RCKT |
| Q2 2024 | 10 | $82.2M | ARVN, EWTX, CRNX, RLYB, RCKT |
| Q1 2024 | 11 | $114.3M | ARVN, EWTX, DCPH, CRNX, RLYB |