In its 13F for Q1 2025 (holdings as of March 31, 2025, filed May 13, 2025), Nuance Investments, LLC reported 48 stock positions worth $1.5 billion . Its top holding was Estee Lauder Companies Class A (EL) at 10.6% of the portfolio, followed by Dentsply Sirona (XRAY, 8.8% ) and Qiagen (QGEN, 7.3% ). Compared with Q4 2024, it opened 5 new positions, sold out of 9, added to 9 and reduced 34. The biggest buy was Hologic (HOLX, shares +624% ) and the biggest sale 3M (MMM, shares −100% ).
Location Kansas City, MO
CIK 0001473182
Portfolio Value $1.5B (Q1 2025) Holdings 48 stocks · $1.5B Holdings quarter Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024 Q1 2024
Stock % Of Portfolio ▼ Shares Held Total Value Change vs Q4 2024 EL Estee Lauder Companies Class A filed as LAUDER ESTEE COS INC 10.63% 2,447,994 $161.6M Reduce -20.8% XRAY Dentsply Sirona Inc. 8.83% 8,987,359 $134.3M Reduce -33.6% QGEN Qiagen N.V. 7.34% 2,778,349 $111.6M Reduce -31.0% CWT California Water Service Grp 6.43% 2,017,511 $97.8M Add +35.4% WERN Werner Enterprises Inc. 5.46% 2,833,654 $83.0M Reduce -21.6% GL Globe Life Inc. 4.81% 554,521 $73.0M Reduce -55.1% MRTN Marten Transport Ltd. 4.73% 5,237,442 $71.9M Add +63.8% HOLX Hologic Inc. 4.39% 1,081,333 $66.8M Add +623.7% HTO H2O America filed as SJW GROUP 4.20% 1,167,968 $63.9M Reduce -7.0% HSIC Henry Schein Inc. 4.10% 910,463 $62.4M Reduce -53.8% SOLV Solventum Corp. 3.50% 700,370 $53.3M Reduce -48.4% NTRS Northern Trust Corp. 3.05% 469,410 $46.3M Reduce -49.3% CLX Clorox Company 2.91% 300,267 $44.2M Reduce -16.4% CVGW Calavo Growers Inc. 2.79% 1,770,251 $42.5M Add +6.4% ROG Rogers Corp. 2.74% 617,347 $41.7M Reduce -23.8% PYCR Paycor HCM Inc. 2.07% 1,401,983 $31.5M New NVST Envista Holdings Corp. 1.66% 1,464,372 $25.3M Reduce -69.5% ATR Aptargroup Inc. 1.41% 144,710 $21.5M Add +69.0% AWK American Water Works Co. Inc. 1.39% 143,054 $21.1M Reduce -14.6% AVO Mission Produce Inc. 1.34% 1,939,257 $20.3M Reduce -0.8% TTC Toro Co. 1.22% 255,292 $18.6M Reduce -33.9% IEX Idex Corp. 1.13% 95,280 $17.2M Reduce -12.8% RGA Reinsurance Group of America 1.08% 83,430 $16.4M Reduce -49.9% KMB Kimberly-Clark Corp. 1.03% 110,595 $15.7M Reduce -78.3% AMAT Applied Materials Inc. 0.97% 101,811 $14.8M Add +135.9% BDX Becton Dickinson and Co. 0.96% 63,551 $14.6M Add +98.3% KNX Knight-Swift Transportation 0.95% 330,596 $14.4M Reduce -70.4% NOC Northrop Grumman Corp. 0.94% 27,996 $14.3M Reduce -69.1% IWS iShares Russell Mid-Cap Valu 0.80% 97,008 $12.2M Reduce -24.8% GGG Graco Inc. 0.56% 102,794 $8.6M Reduce -69.3% POR Portland General Electric Co. 0.56% 192,295 $8.6M Reduce -71.1% LNN Lindsay Corp. 0.56% 66,727 $8.4M Reduce -60.9% NKE Nike Inc. Class B 0.55% 132,438 $8.4M Add +45.9% A Agilent Technologies Inc. 0.55% 71,070 $8.3M New LMT Lockheed Martin Corp. 0.53% 18,187 $8.1M New MTB M & T Bank Corp. filed as M & T BK CORP 0.40% 34,048 $6.1M New TGT Target Corp. 0.40% 57,886 $6.0M Reduce -47.8% CNH CNH Industrial NV 0.40% 491,384 $6.0M Reduce -64.9% NDSN Nordson Corp. 0.40% 29,866 $6.0M New EG Everest Group Ltd. 0.39% 16,404 $6.0M Reduce -17.9% THRM Gentherm Inc. 0.37% 207,667 $5.6M Reduce -41.7% IDA Idacorp Inc. 0.32% 42,101 $4.9M Reduce -89.0% ARE Alexandria Real Estate Equit 0.29% 47,030 $4.4M Reduce -33.4% DOC Healthpeak Properties Inc. 0.29% 215,124 $4.3M Reduce -68.3% INDB Independent Bank Corp. 0.27% 64,800 $4.1M Reduce -36.8% TMO Thermo Fisher Scientific Inc. 0.22% 6,582 $3.3M Reduce -17.8% IJJ iShares S&P Mid-Cap 400 Valu 0.04% 5,247 $628K Add +91.8% MMM 3M Co. 0.02% 1,886 $277K Reduce -99.7%
Other holdings (1): bonds, preferreds, convertibles and warrants · $2.6M (not counted above) Total filed on the 13F, all lines: $1.5B.
Portfolio Sells Q4 2024 → Q1 2025 Portfolio Sells quarter Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024 Q1 2024
Stock Change vs Q4 2024 % Of Portfolio Change To Portfolio ▲ MMM 3M Co. Reduce -99.7% 0.02% −3.04 NVST Envista Holdings Corp. Reduce -69.5% 1.66% −2.09 KMB Kimberly-Clark Corp. Reduce -78.3% 1.03% −1.67 XRAY Dentsply Sirona Inc. Reduce -33.6% 8.83% −1.57 KNX Knight-Swift Transportation Reduce -70.4% 0.95% −1.45 HSIC Henry Schein Inc. Reduce -53.8% 4.10% −1.41 IDA Idacorp Inc. Reduce -89.0% 0.32% −1.38 AVA Avista Corp. Sold out 0.00% −1.16 MKC McCormick & Co.-Non VTG SHRS Sold out 0.00% −1.12 NTRS Northern Trust Corp. Reduce -49.3% 3.05% −0.80 NOC Northrop Grumman Corp. Reduce -69.1% 0.94% −0.78 GL Globe Life Inc. Reduce -55.1% 4.81% −0.77 POR Portland General Electric Co. Reduce -71.1% 0.56% −0.61 ROG Rogers Corp. Reduce -23.8% 2.74% −0.59 GGG Graco Inc. Reduce -69.3% 0.56% −0.58 RGA Reinsurance Group of America Reduce -49.9% 1.08% −0.36 LRCX Lam Research Corp. Sold out 0.00% −0.30 MWA Mueller Water Products Inc. Class A Sold out 0.00% −0.30 LUV Southwest Airlines Co. Sold out 0.00% −0.30 JBHT Hunt (jb) Transprt SVCS Inc. Sold out 0.00% −0.29 TEL Te Connectivity PLC Sold out 0.00% −0.28 DOC Healthpeak Properties Inc. Reduce -68.3% 0.29% −0.27 ST Sensata Technologies Holdplc Sold out 0.00% −0.27 LNN Lindsay Corp. Reduce -60.9% 0.56% −0.26 PII Polaris Inc. Sold out 0.00% −0.26 CNH CNH Industrial NV Reduce -64.9% 0.40% −0.25 THRM Gentherm Inc. Reduce -41.7% 0.37% −0.21 TGT Target Corp. Reduce -47.8% 0.40% −0.21 QGEN Qiagen N.V. Reduce -31.0% 7.34% −0.13 SOLV Solventum Corp. Reduce -48.4% 3.50% −0.12 TTC Toro Co. Reduce -33.9% 1.22% −0.03 INDB Independent Bank Corp. Reduce -36.8% 0.27% +0.00 ARE Alexandria Real Estate Equit Reduce -33.4% 0.29% +0.01 TMO Thermo Fisher Scientific Inc. Reduce -17.8% 0.22% +0.05 EG Everest Group Ltd. Reduce -17.9% 0.39% +0.10 IWS iShares Russell Mid-Cap Valu Reduce -24.8% 0.80% +0.13 AVO Mission Produce Inc. Reduce -0.8% 1.34% +0.20 IEX Idex Corp. Reduce -12.8% 1.13% +0.21 WERN Werner Enterprises Inc. Reduce -21.6% 5.46% +0.21 AWK American Water Works Co. Inc. Reduce -14.6% 1.39% +0.54 CLX Clorox Company Reduce -16.4% 2.91% +0.55 EL Estee Lauder Companies Class A Reduce -20.8% 10.63% +1.24 HTO H2O America Reduce -7.0% 4.20% +1.70
Portfolio Buys Q4 2024 → Q1 2025 Portfolio Buys quarter Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024 Q1 2024
Stock Change vs Q4 2024 % Of Portfolio Change To Portfolio ▼ HOLX Hologic Inc. Add +623.7% 4.39% +3.96 CWT California Water Service Grp Add +35.4% 6.43% +3.70 MRTN Marten Transport Ltd. Add +63.8% 4.73% +2.71 PYCR Paycor HCM Inc. New 2.07% +2.07 CVGW Calavo Growers Inc. Add +6.4% 2.79% +1.08 ATR Aptargroup Inc. Add +69.0% 1.41% +0.87 AMAT Applied Materials Inc. Add +135.9% 0.97% +0.69 BDX Becton Dickinson and Co. Add +98.3% 0.96% +0.66 A Agilent Technologies Inc. New 0.55% +0.55 LMT Lockheed Martin Corp. New 0.53% +0.53 MTB M & T Bank Corp. New 0.40% +0.40 NDSN Nordson Corp. New 0.40% +0.40 NKE Nike Inc. Class B Add +45.9% 0.55% +0.28 IJJ iShares S&P Mid-Cap 400 Valu Add +91.8% 0.04% +0.03
Notes & Other Activity Q4 2024 → Q1 2025 Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.
All Filings Quarter Positions 13F Reported Value Top Holdings Q2 2026 52 $587.7M QGEN, CWT, CLX, TMHC, SOLV Q1 2026 43 $717.1M CWT, MRTN, QGEN, CLX, WERN Q4 2025 45 $907.6M CLX, CWT, MRTN, WERN, AHL Q3 2025 46 $982.1M CLX, CWT, MRTN, INFA, WERN Q2 2025 46 $1.3B CLX, HOLX, EL, CWT, MRTN Q1 2025 48 $1.5B EL, XRAY, QGEN, CWT, WERN Q4 2024 52 $2.5B XRAY, EL, QGEN, GL, HSIC Q3 2024 47 $3.0B XRAY, QGEN, HSIC, NTRS, WERN Q2 2024 48 $3.3B XRAY, MMM, CLX, QGEN, NTRS Q1 2024 49 $3.8B MMM, XRAY, KMB, NTRS, QGEN