Oracle Investment Management Inc.

In its 13F for Q1 2024 (holdings as of March 31, 2024, filed May 15, 2024), Oracle Investment Management Inc. reported 18 stock positions worth $124.2 million. Its top holding was Biohaven (BHVN) at 35.4% of the portfolio, followed by Springworks Therapeutics (SWTX, 16.7%) and Ardelyx (ARDX, 12.0%). Compared with Q4 2023, it opened 3 new positions, sold out of 3, added to 6 and reduced 6. The biggest buy was Springworks Therapeutics (SWTX, shares +168%) and the biggest sale Pacific Biosciences of Calif (PACB, shares −2%).

Most Recent 13F
Q4 2025
Location
GREENWICH, CT
CIK
0001012622
Portfolio Value
$124.2M (Q1 2024)
SEC Filing
0001085146-24-002646 ↗ filed May 15, 2024

Holdings Value

0$50.0M$100.0M$150.0M$200.0M Q1 2024: $124.2M $124.2M Q1 2024 Q2 2024: $93.2M Q2 2024 Q3 2024: $125.1M Q3 2024 Q4 2024: $148.9M Q4 2024 Q1 2025: $153.6M Q1 2025 Q2 2025: $115.6M Q2 2025 Q3 2025: $143.3M Q3 2025 Q4 2025: $152.6M Q4 2025

Holdings 18 stocks · $124.2M

BHVN Biohaven Ltd. 35.44% 804,850 $44.0M Add +12.3%
SWTX Springworks Therapeutics Inc. 16.71% 421,583 $20.8M Add +168.4%
ARDX Ardelyx Inc. 11.99% 2,039,700 $14.9M Add +135.9%
WGS Genedx Holdings Corp. 8.28% 1,126,607 $10.3M Add +531.7%
EYPT Eyepoint Inc. 7.69% 461,857 $9.5M Add +15.0%
QDEL Quidelortho Corp. 6.07% 157,201 $7.5M Reduce -11.0%
PACB Pacific Biosciences of Calif 4.09% 1,356,026 $5.1M Reduce -1.5%
FORA Forian Inc. 3.62% 1,355,807 $4.5M Reduce -0.9%
BCRX Biocryst Pharmaceuticals Inc. 2.19% 535,558 $2.7M No change
IMMP Immutep Ltd.-SP ADR 1.06% 564,879 $1.3M Add +9.4%
CAVA Cava Group Inc. 0.99% 17,600 $1.2M New
AGEN Agenus Inc. 0.50% 1,066,963 $619K Reduce -24.7%
WBA Walgreens Boots Alliance Inc. 0.48% 27,500 $596K New
BIIB Biogen Inc. 0.42% 2,412 $520K No change
OPTINOSE INC 0.38% 325,000 $475K New
BDSX Biodesix Inc. 0.03% 30,351 $43K Reduce -50.2%
AXDXQ Accelerate Diagnostics Inc. 0.03% 42,101 $42K Reduce -62.3%
DMTKQ Dermtech Inc. 0.03% 47,687 $33K No change

Options reported separately and not counted above: WALGREENS BOOTS ALLIANCE INC calls ($8.9M), BIOHAVEN LTD calls ($6.5M), XBI calls ($3.3M), SPRINGWORKS THERAPEUTICS INC calls ($2.1M), ARDELYX INC calls ($2.0M), STAAR SURGICAL CO calls ($1.3M), PACIFIC BIOSCIENCES CALIF IN calls ($938K), EYEPOINT PHARMACEUTICALS INC calls ($591K), PALANTIR TECHNOLOGIES INC calls ($575K).

Portfolio Sells Q4 2023 → Q1 2024

PACB Pacific Biosciences of Calif Reduce -1.5% 4.09% −10.66
QDEL Quidelortho Corp. Reduce -11.0% 6.07% −8.14
TDOC Teladoc Health Inc. Sold out 0.00% −2.66
AGEN Agenus Inc. Reduce -24.7% 0.50% −0.78
FORA Forian Inc. Reduce -0.9% 3.62% −0.75
AXDXQ Accelerate Diagnostics Inc. Reduce -62.3% 0.03% −0.44
VTNRQ Vertex Energy Inc. Sold out 0.00% −0.19
BDSX Biodesix Inc. Reduce -50.2% 0.03% −0.09
INKT Mink Therapeutics Inc. Sold out 0.00% −0.04

Portfolio Buys Q4 2023 → Q1 2024

SWTX Springworks Therapeutics Inc. Add +168.4% 16.71% +10.44
WGS Genedx Holdings Corp. Add +531.7% 8.28% +7.75
ARDX Ardelyx Inc. Add +135.9% 11.99% +6.13
BHVN Biohaven Ltd. Add +12.3% 35.44% +1.95
CAVA Cava Group Inc. New 0.99% +0.99
WBA Walgreens Boots Alliance Inc. New 0.48% +0.48
OPTINOSE INC New 0.38% +0.38
IMMP Immutep Ltd.-SP ADR Add +9.4% 1.06% −0.29
EYPT Eyepoint Inc. Add +15.0% 7.69% −2.45

Options Activity Q4 2023 → Q1 2024

TELADOC HEALTH INC call Sold out 639,600 $13.8Mbefore exit
QUIDELORTHO CORP call Sold out 172,100 $12.7Mbefore exit
WALGREENS BOOTS ALLIANCE INC call Add +310.0% 410,000 $8.9M
BIOHAVEN LTD call Add +59.3% 119,500 $6.5M
XBI SS SPDR S&P Biotech ETF call New 35,000 $3.3M
SPRINGWORKS THERAPEUTICS INC call Reduce -82.8% 42,900 $2.1M
ARDELYX INC call Reduce -81.0% 270,900 $2.0M
STAAR SURGICAL CO call New 35,000 $1.3M
PACIFIC BIOSCIENCES CALIF IN call Reduce -86.0% 250,000 $938K
EYEPOINT PHARMACEUTICALS INC call Reduce -87.0% 28,600 $591K
PALANTIR TECHNOLOGIES INC call New 25,000 $575K

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q4 2025 17$152.6MWGS, ARDX, BHVN, QDEL, FORA
Q3 2025 16$143.3MWGS, BHVN, ARDX, TDOC, PLTR
Q2 2025 9$115.6MWGS, BHVN, ARDX, PLTR, QDEL
Q1 2025 11$153.6MWGS, SWTX, BHVN, ARDX, TDOC
Q4 2024 13$148.9MWGS, BHVN, ARDX, SWTX, QDEL
Q3 2024 15$125.1MWGS, BHVN, PHAT, ARDX, QDEL
Q2 2024 16$93.2MWGS, BHVN, ARDX, SWTX, QDEL
Q1 2024 18$124.2MBHVN, SWTX, ARDX, WGS, EYPT