Pura Vida Investments, LLC

In its 13F for Q1 2024 (holdings as of March 31, 2024, filed May 15, 2024), Pura Vida Investments, LLC reported 30 stock positions worth $146.8 million. Its top holding was Exact Sciences (EXAS) at 22.7% of the portfolio, followed by Establishment Labs (ESTA, 9.1%) and Intuitive Surgical (ISRG, 6.5%). Compared with Q4 2023, it opened 13 new positions, sold out of 8, added to 6 and reduced 9. The biggest buy was a new position in Exact Sciences (EXAS) and the biggest sale an exit from Medavail (MDVLQ).

Most Recent 13F
Q2 2026
Location
NEW YORK, NY
CIK
0001590144
Portfolio Value
$146.8M (Q1 2024)
SEC Filing
0001590144-24-000019 ↗ filed May 15, 2024

Holdings Value

0$50.0M$100.0M$150.0M Q1 2024: $146.8M $146.8M Q1 2024 Q2 2024: $82.7M Q2 2024 Q3 2024: $60.8M Q3 2024 Q4 2024: $18.1M Q4 2024 Q1 2025: $13.7M Q1 2025 Q2 2025: $16.6M Q2 2025 Q3 2025: $16.4M Q3 2025 Q4 2025: $26.8M Q4 2025 Q1 2026: $14.9M Q1 2026 Q2 2026: $37.0M Q2 2026

Holdings 30 stocks · $146.8M

EXAS Exact Sciences Corp. 22.66% 481,910 $33.3M New
ESTA Establishment Labs Holdings 9.07% 261,673 $13.3M Reduce -37.4%
ISRG Intuitive Surgical Inc. 6.54% 24,050 $9.6M New
QTRX Quanterix Corp. 6.03% 375,985 $8.9M Reduce -42.3%
LYRA Lyra Therapeutics Inc. 5.99% 1,413,242 $8.8M No change
GKOS Glaukos Corp. 5.07% 79,000 $7.4M New
NTRA Natera Inc. 4.46% 71,606 $6.5M Reduce -23.0%
MSOS Advisorshares Pure US Cann 3.95% 580,000 $5.8M Add +225.3%
LIVN Livanova PLC 3.43% 90,151 $5.0M Reduce -30.6%
MGX Metagenomi Therapeutics Inc. 3.31% 461,283 $4.9M New
ATEC Alphatec Holdings Inc. 3.01% 320,054 $4.4M Add +4.9%
LUNG Pulmonx Corp. 2.95% 466,787 $4.3M Reduce -2.2%
DXCM Dexcom Inc. 2.83% 30,000 $4.2M Add +14.7%
VKTX Viking Therapeutics Inc. 2.23% 39,868 $3.3M New
INSP Inspire Medical Systems Inc. 2.19% 15,000 $3.2M Add +50.0%
ELAN Elanco Animal Health Inc. 2.14% 193,250 $3.1M Reduce -16.0%
SWAV Shockwave Medical Inc. 1.94% 8,771 $2.9M New
RGEN Repligen Corp. 1.41% 11,225 $2.1M New
GH Guardant Health Inc. 1.40% 100,000 $2.1M Add +566.7%
CUTRQ Cutera Inc. 1.08% 1,078,727 $1.6M Add +0.8%
IMDX Insight Molecular Diagnostic filed as ONCOCYTE CORP 1.05% 523,928 $1.5M Reduce -10.7%
TNDM Tandem Diabetes Care Inc. 1.02% 42,500 $1.5M New
EW Edwards Lifesciences Corp. 1.00% 15,408 $1.5M New
TXG 10X Genomics Inc. Class A 0.97% 38,005 $1.4M New
BAX Baxter International Inc. 0.87% 30,000 $1.3M New
ZIMV Zimvie Inc. 0.82% 73,095 $1.2M New
TMCI Treace Medical Concepts Inc. 0.80% 89,897 $1.2M New
NSPR Inspiremd Inc. 0.73% 450,517 $1.1M No change
MYGN Myriad Genetics Inc. 0.65% 44,725 $954K Reduce -10.6%
RCEL Avita Medical Inc. 0.38% 35,000 $561K Reduce -90.3%

Options reported separately and not counted above: ISHARES TR puts ($148.3M), HUMANA INC calls ($60.7M), STATE STR SPDR S&P 500 ETF T puts ($41.8M), ISHARES TR puts ($38.6M), EXACT SCIENCES CORP calls ($34.2M), SPDR SERIES TRUST puts ($32.3M), INVESCO QQQ TR puts ($26.6M), ARK ETF TR puts ($11.5M), ADVISORSHARES TR calls ($9.5M), LIVANOVA PLC calls ($8.1M), ARK ETF TR puts ($7.5M), GUARDANT HEALTH INC calls ($6.7M), and 6 more.

Other holdings (3): bonds, preferreds, convertibles and warrants · $101K (not counted above)
SecurityClassShares / PrincipalValueChange
TALKW Hudson Executive Inv -CW25 *W EXP 06/21/202 378,000$85KNo change
RCKTW Rocket Pharmaceuticals in-27 *W EXP 09/02/202 42,960$13KNo change
MAPSW WM Technology Inc.-CW24 *W EXP 06/16/202 50,000$3KNo change

Total filed on the 13F, all lines: $147.0M.

Portfolio Sells Q4 2023 → Q1 2024

MDVLQ Medavail Holdings Inc. Sold out 0.00% −78.22
RCEL Avita Medical Inc. Reduce -90.3% 0.38% −0.80
PODD Insulet Corp. Sold out 0.00% −0.65
EVH Evolent Health Inc. Class A Sold out 0.00% −0.51
SOPH Sophia Genetics SA Sold out 0.00% −0.32
DVA Davita Inc. Sold out 0.00% −0.31
CHWY Chewy Inc. Class A Sold out 0.00% −0.23
NYXH Nyxoah SA Sold out 0.00% −0.12
APYX Apyx Medical Corp. Sold out 0.00% −0.05
MYGN Myriad Genetics Inc. Reduce -10.6% 0.65% +0.42
IMDX Insight Molecular Diagnostic Reduce -10.7% 1.05% +0.70
ELAN Elanco Animal Health Inc. Reduce -16.0% 2.14% +1.32
LUNG Pulmonx Corp. Reduce -2.2% 2.95% +1.49
QTRX Quanterix Corp. Reduce -42.3% 6.03% +1.78
LIVN Livanova PLC Reduce -30.6% 3.43% +1.83
NTRA Natera Inc. Reduce -23.0% 4.46% +3.07
ESTA Establishment Labs Holdings Reduce -37.4% 9.07% +6.49

Portfolio Buys Q4 2023 → Q1 2024

EXAS Exact Sciences Corp. New 22.66% +22.66
ISRG Intuitive Surgical Inc. New 6.54% +6.54
GKOS Glaukos Corp. New 5.07% +5.07
MSOS Advisorshares Pure US Cann Add +225.3% 3.95% +3.66
MGX Metagenomi Therapeutics Inc. New 3.31% +3.31
VKTX Viking Therapeutics Inc. New 2.23% +2.23
DXCM Dexcom Inc. Add +14.7% 2.83% +2.06
SWAV Shockwave Medical Inc. New 1.94% +1.94
ATEC Alphatec Holdings Inc. Add +4.9% 3.01% +1.91
INSP Inspire Medical Systems Inc. Add +50.0% 2.19% +1.71
RGEN Repligen Corp. New 1.41% +1.41
GH Guardant Health Inc. Add +566.7% 1.40% +1.31
TNDM Tandem Diabetes Care Inc. New 1.02% +1.02
EW Edwards Lifesciences Corp. New 1.00% +1.00
TXG 10X Genomics Inc. Class A New 0.97% +0.97
BAX Baxter International Inc. New 0.87% +0.87
ZIMV Zimvie Inc. New 0.82% +0.82
TMCI Treace Medical Concepts Inc. New 0.80% +0.80
CUTRQ Cutera Inc. Add +0.8% 1.08% +0.18

Options Activity Q4 2023 → Q1 2024

ISHARES TR put New 705,000 $148.3M
HUMANA INC call New 175,000 $60.7M
STATE STR SPDR S&P 500 ETF T put New 80,000 $41.8M
ISHARES TR put New 659,000 $38.6M
ACWX iShares MSCI Acwi Ex US ETF put Sold out 650,000 $35.1Mbefore exit
EXACT SCIENCES CORP call New 495,100 $34.2M
SPDR SERIES TRUST put New 340,000 $32.3M
SPY SS SPDR S&P 500 ETF Trust-US put Sold out 57,500 $27.3Mbefore exit
INVESCO QQQ TR put New 60,000 $26.6M
ADVISORSHARES TR call Sold out 3,200,000 $22.4Mbefore exit
IXP iShares Global Comm Services put Sold out 102,500 $20.6Mbefore exit
QQQ Invesco QQQ Trust Series 1 put Sold out 50,000 $20.5Mbefore exit
UNH Unitedhealth Group Inc. put Sold out 34,000 $17.9Mbefore exit
GKOS Glaukos Corp. call Sold out 178,500 $14.2Mbefore exit
ISRG Intuitive Surgical Inc. call Sold out 35,000 $11.8Mbefore exit
ARK ETF TR put New 400,000 $11.5M
XITK SS SPDR F Inno Tech ETF put Sold out 120,000 $10.7Mbefore exit
ADVISORSHARES TR call New 950,000 $9.5M
LIVANOVA PLC call New 145,400 $8.1M
ARKK ARK Innovation ETF put Sold out 150,000 $7.9Mbefore exit
ARK ETF TR put New 150,000 $7.5M
GUARDANT HEALTH INC call New 323,300 $6.7M
ARKG ARK Genomic Revolution ETF put Sold out 200,000 $6.6Mbefore exit
SYK Stryker Corp. put Sold out 20,000 $6.0Mbefore exit
RESMED INC put New 28,000 $5.5M
BAUSCH HEALTH COS INC call New 400,000 $4.2M
INSP Inspire Medical Systems Inc. call Sold out 20,000 $4.1Mbefore exit
INMD Inmode Ltd. put Sold out 175,000 $3.9Mbefore exit
ILMN Illumina Inc. call Sold out 27,900 $3.9Mbefore exit
BAX Baxter International Inc. call Sold out 100,000 $3.9Mbefore exit
INSPIRE MED SYS INC put New 17,500 $3.8M
LNTH Lantheus Holdings Inc. call Sold out 60,200 $3.7Mbefore exit
INSPIRE MED SYS INC call New 15,000 $3.2M
NTRA Natera Inc. call Sold out 48,200 $3.0Mbefore exit
GH Guardant Health Inc. call Sold out 100,000 $2.7Mbefore exit
STAA Staar Surgical Co. put Sold out 77,500 $2.4Mbefore exit
INTUITIVE SURGICAL INC call New 6,000 $2.4M
TNDM Tandem Diabetes Care Inc. call Sold out 75,000 $2.2Mbefore exit
QTRX Quanterix Corp. call Sold out 80,000 $2.2Mbefore exit
LIVN Livanova PLC call Sold out 29,700 $1.5Mbefore exit
INMODE LTD put New 61,600 $1.3M
ESTA Establishment Labs Holdings call Sold out 50,000 $1.3Mbefore exit
CUTRQ Cutera Inc. call Sold out 200,000 $705Kbefore exit

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

Notes & Other Activity Q4 2023 → Q1 2024

SOMALOGIC INC *W EXP 08/31/202 Sold out 173,876 $21Kbefore exit

Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 19$37.0MALMR, BBNX, ESTA, IMDX, NVDA
Q1 2026 17$14.9MIMDX, BBNX, ESTA, CAI, NSPR
Q4 2025 18$26.8MBBNX, IMDX, ESTA, CAI, NSPR
Q3 2025 8$16.4MBBNX, IMDX, CAI, ESTA, NSPR
Q2 2025 8$16.6MBBNX, IMDX, CAI, ESTA, OM
Q1 2025 8$13.7MBBNX, IMDX, ESTA, NSPR, KMTS
Q4 2024 9$18.1MESTA, MSOS, LUNG, QTRX, IMDX
Q3 2024 16$60.8MMSOS, ESTA, GKOS, NTRA, ISRG
Q2 2024 25$82.7MESTA, GKOS, ISRG, NTRA, MSOS
Q1 2024 30$146.8MEXAS, ESTA, ISRG, QTRX, LYRA