In its 13F for Q2 2024 (holdings as of June 30, 2024, filed July 12, 2024), Rosalind Advisors, Inc. reported 35 stock positions worth $126.5 million . Its top holding was Delcath Systems (DCTH) at 12.3% of the portfolio, followed by Myomo (MYO, 6.8% ) and Mediwound (MDWD, 6.3% ). Compared with Q1 2024, it opened 5 new positions, sold out of 1, added to 13 and reduced 5. The biggest buy was Delcath Systems (DCTH, shares +155% ) and the biggest sale Lyra Therapeutics (LYRA, shares −10% ).
Location TORONTO, A6
CIK 0001622627
Portfolio Value $126.5M (Q2 2024) Holdings 35 stocks · $126.5M Holdings quarter Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024 Q1 2024
Stock % Of Portfolio ▼ Shares Held Total Value Change vs Q1 2024 DCTH Delcath Systems Inc. 12.28% 2,650,389 $15.5M Add +155.1% MYO Myomo Inc. 6.76% 2,664,999 $8.6M Add +8.9% MDWD Mediwound Ltd. 6.30% 513,490 $8.0M Add +5.7% OPTINOSE INC 6.21% 7,547,148 $7.8M Add +66.2% ABEO Abeona Therapeutics Inc. 5.87% 1,750,000 $7.4M New XERS Xeris Biopharma Holdings Inc. 5.55% 3,120,170 $7.0M Add +10.6% CLRB Cellectar Biosciences Inc. 5.35% 2,705,616 $6.8M Add +335.4% NSPR Inspiremd Inc. 4.96% 2,513,641 $6.3M Add +266.4% CYBIN INC 4.14% 19,300,000 $5.2M Add +38.3% OCUL Ocular Therapeutix Inc. 4.06% 750,000 $5.1M New ABVX Abivax SA-ADR 3.96% 378,416 $5.0M No change PROF Profound Medical Corp. 3.54% 533,333 $4.5M No change CMPS Compass Pathways PLC 3.51% 734,000 $4.4M No change TRVI Trevi Therapeutics Inc. 3.28% 1,391,577 $4.1M Add +50.3% KALV Kalvista Pharmaceuticals Inc. 3.15% 337,985 $4.0M Add +17.4% VRDN Viridian Therapeutics Inc. 3.09% 300,000 $3.9M No change VRNA Verona Pharma Ltd. 2.86% 250,000 $3.6M No change CLEARSIDE BIOMEDICAL INC 2.67% 2,592,593 $3.4M No change OTLK Outlook Therapeutics Inc. 2.63% 450,000 $3.3M Add +44.3% VERU Veru Inc. 1.79% 2,696,003 $2.3M Reduce -40.1% PYPD Polypid Ltd. 1.42% 416,800 $1.8M Add +0.2% RZLT Rezolute Inc. 0.85% 250,000 $1.1M Add +25.0% KPRX Kiora Pharmaceuticals Inc. 0.85% 255,555 $1.1M Reduce -88.9% FBIO Fortress Biotech Inc. 0.82% 607,797 $1.0M No change GERN Geron Corp. 0.67% 200,000 $848K No change UNICYCIVE THERAPEUTICS INC 0.62% 1,571,200 $787K Reduce -16.4% SPRB Spruce Biosciences Inc. 0.62% 1,508,419 $781K No change TLPH Talphera Inc. 0.53% 758,966 $675K No change DERM Journey Medical Corp. 0.51% 114,132 $644K New XAIR Beyond Air Inc. 0.38% 903,614 $486K No change BFRI Biofrontera Inc. 0.36% 504,261 $453K No change LYRA Lyra Therapeutics Inc. 0.23% 1,034,773 $286K Reduce -9.6% NAMS Newamsterdam Pharma Co. NV 0.15% 10,123 $194K New BTAIQ Bioxcel Therapeutics Inc. 0.04% 39,672 $51K New TNXP Tonix Pharmaceuticals Holdin 0.02% 28,154 $20K Reduce -96.9%
Options reported separately and not counted above: CASSAVA SCIENCES INC puts ($1.3M), XBI puts ($1.0M), ANNOVIS BIO INC puts ($839K), G1 THERAPEUTICS INC puts ($305K), ALNYLAM PHARMACEUTICALS INC puts ($0).
Portfolio Sells Q1 2024 → Q2 2024 Portfolio Sells quarter Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024 Q1 2024
Stock Change vs Q1 2024 % Of Portfolio Change To Portfolio ▲ LYRA Lyra Therapeutics Inc. Reduce -9.6% 0.23% −6.43 UNICYCIVE THERAPEUTICS INC Reduce -16.4% 0.62% −1.80 TVRD Cara Therapeutics Inc. Sold out 0.00% −1.32 VERU Veru Inc. Reduce -40.1% 1.79% −1.15 KPRX Kiora Pharmaceuticals Inc. Reduce -88.9% 0.85% −0.67 TNXP Tonix Pharmaceuticals Holdin Reduce -96.9% 0.02% −0.14
Portfolio Buys Q1 2024 → Q2 2024 Portfolio Buys quarter Q2 2026 Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024 Q1 2024
Stock Change vs Q1 2024 % Of Portfolio Change To Portfolio ▼ DCTH Delcath Systems Inc. Add +155.1% 12.28% +7.65 ABEO Abeona Therapeutics Inc. New 5.87% +5.87 OCUL Ocular Therapeutix Inc. New 4.06% +4.06 NSPR Inspiremd Inc. Add +266.4% 4.96% +3.44 CLRB Cellectar Biosciences Inc. Add +335.4% 5.35% +3.04 DERM Journey Medical Corp. New 0.51% +0.51 RZLT Rezolute Inc. Add +25.0% 0.85% +0.37 TRVI Trevi Therapeutics Inc. Add +50.3% 3.28% +0.29 NAMS Newamsterdam Pharma Co. NV New 0.15% +0.15 BTAIQ Bioxcel Therapeutics Inc. New 0.04% +0.04 OPTINOSE INC Add +66.2% 6.21% +0.01 KALV Kalvista Pharmaceuticals Inc. Add +17.4% 3.15% −0.05 MDWD Mediwound Ltd. Add +5.7% 6.30% −0.17 XERS Xeris Biopharma Holdings Inc. Add +10.6% 5.55% −0.28 PYPD Polypid Ltd. Add +0.2% 1.42% −0.37 MYO Myomo Inc. Add +8.9% 6.76% −0.72 OTLK Outlook Therapeutics Inc. Add +44.3% 2.63% −0.85 CYBIN INC Add +38.3% 4.14% −1.26
Options Activity Q1 2024 → Q2 2024 Security Type Change vs Q1 2024 Underlying Shares Value ▼ CASSAVA SCIENCES INC put New 3,673 $1.3M XBI SS SPDR S&P Biotech ETF put Reduce -55.2% 22,403 $1.0M ANNOVIS BIO INC put New 24,154 $839K G1 THERAPEUTICS INC put New 19,018 $305K INVESCO QQQ TR put Sold out 100,000 $7Kbefore exit ALNYLAM PHARMACEUTICALS INC put New 700 $0 AMYLYX PHARMACEUTICALS INC call Sold out 50,000 $0before exit
Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.
All Filings Quarter Positions 13F Reported Value Top Holdings Q2 2026 29 $266.2M DCTH, FENC, XERS, SVRA, VSTM Q1 2026 32 $244.1M DCTH, XERS, FENC, SVRA, PCVX Q4 2025 29 $274.5M DCTH, SVRA, FENC, XERS, VRDN Q3 2025 29 $283.0M DCTH, CYTK, FENC, VSTM, RZLT Q2 2025 29 $206.6M DCTH, FENC, CYTK, OCUL, IDYA Q1 2025 31 $205.2M DCTH, VSTM, XERS, MYO, IDYA Q4 2024 Amended 28 $185.7M DCTH, MYO, MDWD, CMRX, XERS Q3 2024 29 $150.7M DCTH, MYO, CRMD, ABEO, MDWD Q2 2024 35 $126.5M DCTH, MYO, MDWD, OPTINOSE INC, ABEO Q1 2024 31 $106.9M MYO, LYRA, MDWD, OPTINOSE INC, XERS