Takeda Pharmaceutical Co. Ltd.

In its 13F for Q4 2024 (holdings as of December 31, 2024, filed February 12, 2025), Takeda Pharmaceutical Co. Ltd. reported 11 stock positions worth $26.6 million. Its top holding was Hillevax (HLVX) at 52.4% of the portfolio, followed by Ovid Therapeutics (OVID, 26.4%) and Xilio Therapeutics (XLO, 5.3%). Compared with Q3 2024, it opened 2 new positions and sold out of 1. The biggest buy was a new position in Lyell Immunopharma (LYEL) and the biggest sale an exit from Wave Life Sciences (WVE).

Most Recent 13F
Q3 2025
Location
Tokyo, M0
CIK
0001395064
Portfolio Value
$26.6M (Q4 2024)
SEC Filing
0001395064-25-000019 ↗ filed Feb 12, 2025

Holdings Value

0$100.0M$200.0M$300.0M Q1 2024: $289.0M Q1 2024 Q2 2024: $232.3M Q2 2024 Q3 2024: $38.0M Q3 2024 Q4 2024: $26.6M $26.6M Q4 2024 Q1 2025: $16.2M Q1 2025 Q2 2025: $19.6M Q2 2025 Q3 2025: $16.4M Q3 2025

Holdings 11 stocks · $26.6M

HLVX Hillevax Inc. 52.40% 6,724,000 $13.9M No change
OVID Ovid Therapeutics Inc. 26.40% 7,531,996 $7.0M No change
XLO Xilio Therapeutics Inc. 5.33% 1,475,121 $1.4M No change
EQ Equillium Inc. 5.15% 1,824,977 $1.4M No change
STTK Shattuck Labs Inc. 2.35% 515,619 $624K No change
AMWL American Well Corp. Class A 2.12% 77,733 $564K No change
LYEL Lyell Immunopharma Inc. 1.98% 823,317 $527K New
TSBX Turnstone Biologics Corp. 1.69% 895,824 $448K No change
THRD Third Harmonic Bio Inc. 1.43% 36,835 $379K New
RANI Rani Therapeutics Holdings Class A 1.05% 203,190 $278K No change
LAB Standard Biotools Inc. 0.11% 16,515 $29K No change

Portfolio Sells Q3 2024 → Q4 2024

WVE Wave Life Sciences Ltd. Sold out 0.00% −29.10

Portfolio Buys Q3 2024 → Q4 2024

LYEL Lyell Immunopharma Inc. New 1.98% +1.98
THRD Third Harmonic Bio Inc. New 1.43% +1.43

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q3 2025 8$16.4MOVID, EQ, XLO, STTK, LYEL
Q2 2025 11$19.6MHLVX, OVID, XLO, AMWL, EQ
Q1 2025 11$16.2MHLVX, OVID, XLO, EQ, AMWL
Q4 2024 11$26.6MHLVX, OVID, XLO, EQ, STTK
Q3 2024 10$38.0MHLVX, WVE, OVID, STTK, EQ
Q2 2024 13$232.3MDNLI, HLVX, PHAT, WVE, OVID
Q1 2024 15$289.0MHLVX, DNLI, PHAT, OVID, STTK