Alx Oncology HoldingsALXO
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 57 institutions reported holding Alx Oncology Holdings Inc. (ALXO) in their 13F filings, down 4 from Q3 2025. 6 opened new positions and 10 sold out. The largest holders were venBio Partners LLC ($11.0M), Redmile Group, LLC ($3.7M) and Millennium Management ($3.6M). 4 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Alx Oncology Holdings Inc.
- CUSIP
- 00166B105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 6 | $124K |
| Exits | 10 | $2.3M |
All 13F filers, Q3 2025 → Q4 2025: 2,730,387 shares bought and 1,406,751 shares sold, net +1,323,636 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 57 holders
| venBio Partners LLC | 5.07% | No change | 9,699,925 | $11.0M |
| Redmile Group, LLC | 0.27% | Reduce -2.0% | 3,264,718 | $3.7M |
| Millennium Management | 0.00% | Add +22.2% | 3,204,619 | $3.6M |
| Almitas Capital LLC | 0.63% | No change | 2,536,891 | $2.9M |
| Vanguard Group Inc. | 0.00% | Add +6.7% | 1,630,940 | $1.8M |
| Driehaus Capital Management LLC | 0.01% | Add +78.8% | 1,422,882 | $1.6M |
| Acadian Asset Management LLC | 0.00% | Add +12.6% | 1,374,273 | $1.6M |
| UBS Group AG | 0.00% | Add +401.8% | 865,991 | $979K |
| Two Sigma Advisers, LP | 0.00% | Reduce -1.3% | 710,400 | $803K |
| Two Sigma Investments, LP | 0.00% | Add +5.5% | 640,205 | $723K |
| Bank of America Corp. | 0.00% | Add +0.2% | 531,845 | $601K |
| Bank of Montreal | 0.00% | No change | 474,781 | $537K |
| BlackRock, Inc. | 0.00% | Add +0.6% | 450,430 | $509K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 41,000 | $508K |
| Renaissance Technologies | 0.00% | Add +157.2% | 423,099 | $478K |
| Geode Capital Management, LLC | 0.00% | Add +0.4% | 353,696 | $400K |
| Jane Street Group, LLC | 0.00% | Add +3.1% | 185,961 | $210K |
| Susquehanna International Group, LLP | 0.00% | Add +33.6% | 151,027 | $171K |
| Northern Trust Corp. | 0.00% | Add +56.7% | 149,097 | $168K |
| State Street Corp. | 0.00% | Add +11.0% | 124,228 | $140K |
| Seven Fleet Capital Management LP | 0.09% | — | 117,817 | $133K |
| Bank of Nova Scotia | 0.00% | No change | 105,858 | $120K |
| Gsa Capital Partners LLP | 0.01% | Add +5.1% | 92,654 | $105K |
| Ieq Capital, LLC | 0.00% | No change | 92,233 | $104K |
| Morgan Stanley | 0.00% | Reduce -1.8% | 83,757 | $95K |
| Bridgeway Capital Management, LLC | 0.00% | Add +111.3% | 76,072 | $86K |
| Citadel Advisors | 0.00% | New | 56,732 | $64K |
| Nan Fung Trinity (hk) Ltd. | 0.00% | No change | 41,950 | $47K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Reduce -0.2% | 37,992 | $41K |
| Callan Family Office, LLC | 0.00% | Add +43.1% | 28,308 | $32K |
| Marshall Wace, LLP | 0.00% | Reduce -33.4% | 26,376 | $30K |
| HC Advisors, LLC | 0.02% | Add +9.4% | 23,900 | $27K |
| Lido Advisors, LLC | 0.00% | No change | 13,220 | $24K |
| Point72 Asset Management | 0.00% | New | 20,217 | $23K |
| JSF Financial, LLC | 0.00% | No change | 17,500 | $20K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -7.2% | 17,262 | $20K |
| NINE MASTS CAPITAL Ltd | 0.00% | New | 15,475 | $17K |
| Moneta Group Investment Advisors LLC | 0.00% | No change | 15,196 | $17K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -26.6% | 15,102 | $17K |
| Virtu Financial LLC | 0.00% | New | 13,702 | $15K |
| FMR LLC | 0.00% | No change | 12,986 | $15K |
| Abel Hall, LLC | 0.00% | No change | 12,598 | $14K |
| Barclays PLC | 0.00% | Reduce -0.5% | 10,515 | $12K |
| HSBC Holdings PLC | 0.00% | Reduce -6.6% | 10,105 | $12K |
| Simplex Trading, LLC | 0.00% | New | 3,553 | $4K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -18.1% | 3,142 | $4K |
| Torren Management, LLC | 0.00% | — | 1,632 | $2K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 1,106 | $1K |
| Bradley & Co. Private Wealth Management, LLC | 0.00% | No change | 1,000 | $1K |
| Royal Bank of Canada | 0.00% | Reduce -12.7% | 963 | $1K |
| Group One Trading LLC | 0.00% | New | 518 | $585 |
| BNP Paribas Financial Markets | 0.00% | No change | 480 | $542 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -2.4% | 412 | $466 |
| PNC Financial Services Group, Inc. | 0.00% | No change | 100 | $113 |
| JPMorgan Chase & Co. | 0.00% | Reduce -99.8% | 99 | $112 |
| Optiver Holding B.V. | 0.00% | Reduce -3.6% | 27 | $31 |
| Cwm, LLC | 0.00% | Reduce -33.3% | 96 | $0 |
"% of holder's portfolio" is ALXO's weight in each manager's 13F, not the share of Alx Oncology Holdings Inc. the manager owns.