AnnexonANNX
13F holders, Q3 2025 (September 30)At the end of Q3 2025, 144 institutions reported holding Annexon Inc. (ANNX) in their 13F filings, up 15 from Q2 2025. 32 opened new positions and 17 sold out. The largest holders were FMR LLC ($33.8M), BlackRock, Inc. ($24.1M) and BVF Inc. ($21.4M). 5 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Annexon Inc.
- CUSIP
- 03589W102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 32 | $22.6M |
| Exits | 17 | $19.5M |
All 13F filers, Q2 2025 → Q3 2025: 16,581,035 shares bought and 14,906,047 shares sold, net +1,674,988 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 144 holders
| FMR LLC | 0.00% | Reduce -29.4% | 11,081,163 | $33.8M |
| BlackRock, Inc. | 0.00% | Reduce -0.8% | 7,899,008 | $24.1M |
| BVF Inc. | 0.87% | No change | 7,000,000 | $21.4M |
| Redmile Group, LLC | 1.87% | No change | 6,300,644 | $19.2M |
| Vanguard Group Inc. | 0.00% | Add +8.7% | 5,835,112 | $17.8M |
| Bain Capital Life Sciences Investors, LLC | 1.06% | No change | 5,249,069 | $16.0M |
| Bellevue Group AG | 0.33% | No change | 5,157,290 | $15.7M |
| Morgan Stanley | 0.00% | Add +263.9% | 3,029,848 | $9.2M |
| Millennium Management | 0.01% | Add +12.3% | 2,822,823 | $8.6M |
| Woodline Partners LP | 0.04% | Add +150.4% | 2,638,275 | $8.0M |
| Opaleye Management Inc. | 1.13% | New | 2,600,000 | $7.9M |
| Candriam S.C.A. | 0.04% | No change | 2,534,230 | $7.7M |
| Geode Capital Management, LLC | 0.00% | Add +6.7% | 2,436,944 | $7.4M |
| Goldman Sachs Group Inc. | 0.00% | Add +47.6% | 2,406,432 | $7.3M |
| Ameriprise Financial Inc. | 0.00% | Add +1.2% | 2,192,354 | $6.7M |
| Tetragon Partners GP Ltd | 1.56% | Reduce -24.8% | 2,112,455 | $6.4M |
| State Street Corp. | 0.00% | Add +3.5% | 2,050,308 | $6.3M |
| Sphera Funds Management LTD. | 1.30% | Add +1.7% | 1,794,387 | $5.5M |
| Deutsche Bank AG | 0.00% | Add +194.1% | 1,504,349 | $4.6M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | New | 1,500,000 | $4.6M |
| Balyasny Asset Management L.P. | 0.01% | New | 1,297,260 | $4.0M |
| Bank of America Corp. | 0.00% | Reduce -10.9% | 1,294,302 | $3.9M |
| J. Goldman & Co LP | 0.13% | New | 1,107,001 | $3.4M |
| Mutual of America Capital Management LLC | 0.03% | Reduce -1.1% | 1,066,932 | $3.3M |
| Massachusetts Financial Services Co. | 0.00% | Reduce -0.7% | 980,285 | $3.0M |
| Sirios Capital Management L P | 0.39% | Reduce -2.0% | 970,200 | $3.0M |
| Rhenman & Partners Asset Management AB | 0.28% | Add +78.9% | 823,000 | $2.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +8.5% | 790,250 | $2.4M |
| Northern Trust Corp. | 0.00% | Add +6.0% | 787,708 | $2.4M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -13.8% | 766,955 | $2.3M |
| Renaissance Technologies | 0.00% | Reduce -3.1% | 753,579 | $2.3M |
| Nuveen, LLC | 0.00% | Add +166.7% | 682,558 | $2.1M |
| Kennedy Capital Management LLC | 0.04% | Reduce -25.1% | 640,460 | $2.0M |
| Deerfield Management Company, L.P. | 0.03% | No change | 583,913 | $1.8M |
| AQR Capital Management | 0.00% | Add +72.9% | 574,123 | $1.8M |
| Qube Research & Technologies Ltd | 0.00% | Add +34.8% | 572,644 | $1.7M |
| Acadian Asset Management LLC | 0.00% | Add +13.5% | 532,363 | $1.6M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -4.6% | 484,775 | $1.5M |
| Board of Trustees of The Leland Stanford Junior University | 0.17% | No change | 482,550 | $1.5M |
| Hennion & Walsh Asset Management, Inc. | 0.05% | Reduce -1.8% | 475,929 | $1.5M |
| Wells Fargo & Company | 0.00% | Add +8.6% | 409,477 | $1.2M |
| Parkman Healthcare Partners LLC | 0.14% | Add +0.4% | 405,953 | $1.2M |
| Susquehanna Portfolio Strategies, LLC | 0.02% | Add +70.3% | 353,744 | $1.1M |
| UBS Group AG | 0.00% | Add +6.5% | 346,139 | $1.1M |
| Bank of New York Mellon Corp | 0.00% | Add +2.4% | 308,188 | $940K |
| Point72 Europe (London) LLP | 0.05% | Add +46.5% | 302,861 | $924K |
| Royal Bank of Canada | 0.00% | Add +16.6% | 285,848 | $871K |
| Two Sigma Investments, LP | 0.00% | Add +38.8% | 279,134 | $851K |
| ExodusPoint Capital Management, LP | 0.01% | Add +295.1% | 243,755 | $743K |
| SummitTX Capital, L.P. | 0.03% | New | 241,991 | $738K |
| American Century Companies Inc. | 0.00% | Add +12.1% | 236,736 | $722K |
| J. Safra Sarasin Holding AG | 0.01% | Reduce -41.5% | 223,221 | $681K |
| Jane Street Group, LLC | 0.00% | Add +50.5% | 219,494 | $669K |
| Schonfeld Strategic Advisors LLC | 0.00% | Reduce -20.2% | 212,219 | $647K |
| Invesco Ltd. | 0.00% | Add +34.3% | 201,945 | $616K |
| Citadel Advisors | 0.00% | Add +1162.5% | 167,500 | $511K |
| Susquehanna International Group, LLP | 0.00% | Reduce -43.3% | 151,250 | $461K |
| Osaic Holdings, Inc. | 0.00% | Add +83.4% | 147,375 | $459K |
| Ieq Capital, LLC | 0.00% | Add +10.7% | 150,322 | $458K |
| Barclays PLC | 0.00% | Reduce -16.7% | 147,930 | $451K |
| XTX Topco Ltd | 0.02% | New | 147,840 | $451K |
| Alliancebernstein L.P. | 0.00% | No change | 140,740 | $429K |
| Bridgeway Capital Management, LLC | 0.01% | Add +40.9% | 137,800 | $420K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -1.0% | 132,673 | $405K |
| Rhumbline Advisers | 0.00% | Reduce -3.6% | 132,603 | $404K |
| Park Avenue Securities LLC | 0.00% | No change | 113,068 | $345K |
| Quarry LP | 0.09% | Add +155.0% | 110,000 | $336K |
| Brevan Howard Capital Management LP | 0.00% | Add +77.5% | 94,554 | $288K |
| Point72 Asset Management | 0.00% | New | 90,049 | $275K |
| DNB Asset Management AS | 0.00% | Reduce -15.1% | 84,523 | $258K |
| HRT Financial LP | 0.00% | New | 84,582 | $257K |
| Cinctive Capital Management LP | 0.01% | Reduce -51.7% | 65,466 | $200K |
| Alps Advisors Inc. | 0.00% | Reduce -19.1% | 47,879 | $146K |
| JPMorgan Chase & Co. | 0.00% | Reduce -11.2% | 46,886 | $143K |
| TD Asset Management Inc | 0.00% | No change | 46,848 | $143K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -14.2% | 44,979 | $137K |
| MetLife Investment Management, LLC | 0.00% | Reduce -24.4% | 44,632 | $136K |
| Allegheny Financial Group | 0.02% | No change | 42,900 | $131K |
| Virtus Investment Advisers, LLC | 0.04% | Add +21.0% | 41,987 | $128K |
| Citizens Financial Group Inc. | 0.00% | Add +14.3% | 40,000 | $122K |
| Group One Trading LLC | 0.00% | New | 35,565 | $108K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +60.0% | 35,261 | $108K |
| Lido Advisors, LLC | 0.00% | Reduce -0.1% | 34,952 | $107K |
| New York State Common Retirement Fund | 0.00% | No change | 34,479 | $105K |
| Comerica Bank | 0.00% | Add +26.4% | 32,357 | $99K |
| Atom Investors LP | 0.01% | New | 30,453 | $93K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +36.5% | 28,105 | $86K |
| Axq Capital, LP | 0.03% | New | 27,867 | $85K |
| Forefront Analytics, LLC | 0.08% | Reduce -2.0% | 27,027 | $82K |
| Forefront Wealth Partners, LLC | 0.02% | New | 27,027 | $82K |
| Intech Investment Management LLC | 0.00% | Reduce -49.4% | 26,676 | $81K |
| HSBC Holdings PLC | 0.00% | Reduce -13.8% | 25,721 | $78K |
| Two Sigma Advisers, LP | 0.00% | New | 23,800 | $73K |
| Cwm, LLC | 0.00% | Add +32.5% | 23,488 | $72K |
| Cubist Systematic Strategies, LLC | 0.00% | New | 22,771 | $69K |
| Jacobs Levy Equity Management, Inc. | 0.00% | New | 22,589 | $69K |
| Matauro, LLC | 0.01% | Add +85.6% | 20,572 | $63K |
| ProShare Advisors LLC | 0.00% | Reduce -14.5% | 20,288 | $62K |
| Raymond James Financial Inc. | 0.00% | New | 20,000 | $61K |
| EntryPoint Capital, LLC | 0.02% | New | 19,971 | $61K |
| BNP Paribas Financial Markets | 0.00% | Add +97.8% | 19,739 | $60K |
| Corient Private Wealth LP | 0.00% | New | 19,665 | $60K |
| Voya Investment Management LLC | 0.00% | Reduce -29.6% | 19,318 | $59K |
| Russell Investments Group, Ltd. | 0.00% | New | 18,220 | $56K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | New | 17,205 | $53K |
| Coastal Bridge Advisors, LLC | 0.00% | No change | 17,000 | $52K |
| Creative Planning | 0.00% | New | 15,451 | $47K |
| Balefire, LLC | 0.01% | New | 15,000 | $46K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +7.8% | 13,244 | $40K |
| 49 Wealth Management, LLC | 0.00% | No change | 12,083 | $37K |
| Prudential Financial Inc. | 0.00% | No change | 11,670 | $36K |
| SG Americas Securities, LLC | 0.00% | New | 10,997 | $34K |
| Victory Capital Management Inc. | 0.00% | Reduce -3.3% | 11,021 | $34K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | No change | 10,700 | $33K |
| CIBC Bancorp USA Inc. | 0.00% | — | 10,208 | $31K |
| Harbor Advisors LLC | 0.00% | No change | 10,000 | $31K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 9,689 | $30K |
| Legal & General Group Plc | 0.00% | No change | 8,476 | $26K |
| Citigroup Inc. | 0.00% | Reduce -81.9% | 6,828 | $21K |
| Sterling Capital Management LLC | 0.00% | Add +139.6% | 6,607 | $20K |
| Arax Advisory Partners | 0.00% | New | 6,530 | $20K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -60.8% | 6,096 | $19K |
| Geneos Wealth Management Inc. | 0.00% | New | 6,000 | $18K |
| California State Teachers Retirement System | 0.00% | New | 5,995 | $18K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.2% | 4,248 | $13K |
| Amalgamated Bank | 0.00% | No change | 3,370 | $10K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -3.5% | 2,613 | $8K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -13.4% | 2,364 | $7K |
| Optiver Holding B.V. | 0.00% | New | 1,304 | $4K |
| PNC Financial Services Group, Inc. | 0.00% | Add +8.6% | 1,123 | $3K |
| Clearstead Advisors, LLC | 0.00% | New | 355 | $1K |
| IFP Advisors, Inc | 0.00% | Add +224.1% | 350 | $1K |
| Daiwa Securities Group Inc. | 0.00% | No change | 352 | $1K |
| HighMark Wealth Management LLC | 0.00% | No change | 300 | $915 |
| EverSource Wealth Advisors, LLC | 0.00% | Add +17.5% | 296 | $903 |
| Essential Partners LLC | 0.00% | Add +45.0% | 293 | $894 |
| Physician Wealth Advisors, Inc. | 0.00% | New | 269 | $821 |
| Rothschild Investment LLC | 0.00% | No change | 165 | $503 |
| Allworth Financial LP | 0.00% | Add +237.8% | 152 | $464 |
| Sunbelt Securities, Inc. | 0.00% | New | 87 | $265 |
| True Wealth Design, LLC | 0.00% | New | 55 | $168 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -13.3% | 26 | $79 |
| Advisory Services Network, LLC | 0.00% | New | 23 | $70 |
| Farther Finance Advisors, LLC | 0.00% | No change | 1 | $3 |
"% of holder's portfolio" is ANNX's weight in each manager's 13F, not the share of Annexon Inc. the manager owns.