Caris Life SciencesCAI
13F holders, Q3 2025 (September 30)138holders +22
52new positions
30sold out
9famous investors
$30.07avg. 13F price*
At the end of Q3 2025, 138 institutions reported holding Caris Life Sciences Inc. (CAI) in their 13F filings, up 22 from Q2 2025. 52 opened new positions and 30 sold out. The largest holders were Sixth Street Partners Management Company, L.P. ($737.7M), Coatue Management ($306.8M) and FMR LLC ($291.4M). 9 famous investors held it, including Philippe Laffont (0.8% of Coatue Management's portfolio), Israel Englander (0.1% of Millennium Management's portfolio) and Paul Tudor Jones (0.1% of Tudor Investment Corporation's portfolio).
- Company
- Caris Life Sciences Inc.
- CUSIP
- 142152107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 52 | $64.5M |
| Exits | 30 | $78.7M |
All 13F filers, Q2 2025 → Q3 2025: 11,349,971 shares bought and 6,911,471 shares sold, net +4,438,500 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 138 holders
| Sixth Street Partners Management Company, L.P. | 63.36% | No change | 24,385,399 | $737.7M |
| Coatue Management | 0.75% | No change | 10,142,198 | $306.8M |
| FMR LLC | 0.02% | Add +11.6% | 9,633,435 | $291.4M |
| T. Rowe Price Investment Management, Inc. | 0.15% | Add +9.9% | 8,025,759 | $242.8M |
| Braidwell LP | 8.95% | No change | 7,316,142 | $221.3M |
| T. Rowe Price Associates Inc. | 0.02% | Add +2.4% | 6,924,745 | $209.5M |
| Silver Lake Group, L.L.C. | 3.12% | No change | 5,291,006 | $160.1M |
| Millennium Management | 0.10% | Add +12.1% | 3,938,072 | $119.1M |
| PointState Capital LP | 2.11% | Add +55.5% | 3,883,721 | $117.5M |
| Neuberger Berman Group LLC | 0.08% | Reduce -30.4% | 4,345,042 | $109.1M |
| Orbimed Advisors LLC | 2.20% | No change | 3,034,858 | $91.8M |
| Ameriprise Financial Inc. | 0.01% | Add +3.3% | 1,679,468 | $50.8M |
| Morgan Stanley | 0.00% | Add +90.5% | 1,534,423 | $46.4M |
| Clearbridge Investments, LLC | 0.03% | Add +9.9% | 1,381,230 | $41.8M |
| Canada Pension Plan Investment Board | 0.03% | No change | 1,322,752 | $40.0M |
| Longaeva Partners L.P. | 8.41% | Reduce -11.9% | 1,285,968 | $38.9M |
| Alliancebernstein L.P. | 0.01% | Add +28.2% | 1,201,985 | $36.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Add +39.5% | 1,116,191 | $33.8M |
| Alyeska Investment Group, L.P. | 0.10% | Add +192.8% | 1,101,071 | $33.3M |
| Perceptive Advisors LLC | 0.97% | No change | 1,098,163 | $33.2M |
| Ghisallo Capital Management LLC | 1.04% | No change | 1,048,163 | $31.7M |
| Massachusetts Financial Services Co. | 0.01% | Reduce -7.5% | 971,330 | $29.4M |
| JPMorgan Chase & Co. | 0.00% | Reduce -8.2% | 858,105 | $26.0M |
| Lord, Abbett & Co. LLC | 0.08% | New | 850,000 | $25.7M |
| Invesco Ltd. | 0.00% | Add +58.6% | 803,802 | $24.3M |
| Rock Springs Capital Management LP | 1.41% | No change | 793,651 | $24.0M |
| Woodline Partners LP | 0.10% | Reduce -42.0% | 723,163 | $21.9M |
| Janus Henderson Group PLC | 0.01% | Reduce -25.3% | 664,438 | $20.1M |
| Point72 (DIFC) Ltd | 1.38% | Add +1109.4% | 654,792 | $19.8M |
| BlackRock, Inc. | 0.00% | Add +109.3% | 647,081 | $19.6M |
| Bank of America Corp. | 0.00% | Add +1120.5% | 429,478 | $13.0M |
| Geode Capital Management, LLC | 0.00% | Add +69.3% | 398,328 | $12.0M |
| First Light Asset Management, LLC | 1.12% | Reduce -8.8% | 403,924 | $11.9M |
| Walleye Capital LLC | 0.09% | Add +745.5% | 320,669 | $9.7M |
| Goldman Sachs Group Inc. | 0.00% | Add +54.8% | 282,209 | $8.5M |
| Lazard Asset Management LLC | 0.01% | Add +63.3% | 277,537 | $8.4M |
| Tudor Investment Corporation | 0.05% | No change | 264,551 | $8.0M |
| Freestone Grove Partners LP | 0.06% | Add +402.8% | 251,389 | $7.6M |
| Point72 Asset Management | 0.02% | Reduce -46.2% | 246,624 | $7.5M |
| ARK Investment Management | 0.04% | Add +421.5% | 245,350 | $7.4M |
| UBS Group AG | 0.00% | New | 235,873 | $7.1M |
| FIL Ltd | 0.01% | Reduce -23.7% | 225,920 | $6.8M |
| Renaissance Technologies | 0.01% | New | 225,100 | $6.8M |
| TD Asset Management Inc | 0.01% | Add +11.3% | 222,336 | $6.7M |
| Franklin Resources Inc. | 0.00% | Reduce -58.8% | 216,964 | $6.6M |
| Vanguard Group Inc. | 0.00% | Add +17.0% | 175,544 | $5.3M |
| Holocene Advisors, LP | 0.01% | Reduce -1.1% | 171,127 | $5.2M |
| State Street Corp. | 0.00% | New | 155,340 | $4.7M |
| State of Wisconsin Investment Board | 0.01% | No change | 150,000 | $4.5M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +388.0% | 110,084 | $3.3M |
| Seven Grand Managers, LLC | 0.25% | Add +100.0% | 100,000 | $3.0M |
| Raymond James Financial Inc. | 0.00% | Add +3235.3% | 94,888 | $2.9M |
| Rakuten Investment Management, Inc. | 0.01% | — | 14,518 | $2.8M |
| Pura Vida Investments, LLC | 16.58% | Add +99.9% | 89,940 | $2.7M |
| Jennison Associates LLC | 0.00% | Reduce -70.5% | 84,459 | $2.6M |
| Marshall Wace, LLP | 0.00% | Add +119.1% | 82,975 | $2.5M |
| Burkehill Global Management, LP | 0.13% | No change | 75,000 | $2.3M |
| Quantinno Capital Management LP | 0.01% | New | 72,223 | $2.2M |
| Cubist Systematic Strategies, LLC | 0.03% | Add +3436.6% | 70,731 | $2.1M |
| Sumitomo Mitsui Trust Group, Inc. | 0.00% | Add +388.9% | 59,552 | $1.8M |
| Soros Fund Management | 0.04% | Add +11.3% | 55,650 | $1.7M |
| SRS Investment Management, LLC | 0.02% | No change | 50,000 | $1.5M |
| D. E. Shaw & Co. | 0.00% | Add +563.8% | 49,785 | $1.5M |
| Citigroup Inc. | 0.00% | Add +403608.3% | 48,445 | $1.5M |
| Amova Asset Management Americas, Inc. | 0.01% | New | 47,371 | $1.4M |
| Northern Trust Corp. | 0.00% | New | 45,595 | $1.4M |
| Gotham Asset Management | 0.00% | New | 33,203 | $1.0M |
| Qube Research & Technologies Ltd | 0.00% | Add +322.4% | 32,752 | $991K |
| Dark Forest Capital Management LP | 0.04% | New | 31,657 | $958K |
| Verition Fund Management LLC | 0.01% | New | 30,910 | $935K |
| Susquehanna International Group, LLP | 0.00% | New | 28,988 | $877K |
| Renaissance Capital LLC | 0.48% | New | 28,460 | $861K |
| XTX Topco Ltd | 0.04% | New | 28,081 | $849K |
| Deutsche Bank AG | 0.00% | No change | 25,290 | $765K |
| Atika Capital Management LLC | 0.06% | No change | 25,000 | $756K |
| Bank of New York Mellon Corp | 0.00% | New | 24,869 | $752K |
| WPWealth LLP | 0.11% | New | 23,036 | $697K |
| Nuveen, LLC | 0.00% | New | 22,413 | $678K |
| Engineers Gate Manager LP | 0.01% | New | 22,028 | $666K |
| Rhumbline Advisers | 0.00% | New | 21,497 | $650K |
| Park Avenue Securities LLC | 0.00% | New | 20,730 | $627K |
| MSA Advisors, LLC | 0.15% | No change | 19,200 | $581K |
| Ieq Capital, LLC | 0.00% | New | 17,141 | $519K |
| Man Group plc | 0.00% | New | 16,078 | $486K |
| LPL Financial LLC | 0.00% | Add +74.0% | 15,991 | $484K |
| Harbor Investment Advisory, LLC | 0.04% | New | 15,650 | $473K |
| Jane Street Group, LLC | 0.00% | New | 14,595 | $441K |
| US Bancorp \de | 0.00% | Add +7.2% | 12,722 | $385K |
| Americana Partners, LLC | 0.01% | New | 12,433 | $376K |
| Triton Wealth Management, PLLC | 0.12% | No change | 10,505 | $327K |
| Perbak Capital Partners LLP | 0.06% | New | 10,703 | $324K |
| CastleKnight Management LP | 0.02% | Reduce -90.8% | 10,436 | $316K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | New | 10,372 | $314K |
| Worldquant Millennium Advisors LLC | 0.00% | New | 10,092 | $305K |
| Treasurer of the State of North Carolina | 0.00% | New | 10,073 | $305K |
| Bellevue Group AG | 0.01% | Reduce -4.0% | 9,605 | $291K |
| Sandia Investment Management LP | 0.79% | Reduce -14.0% | 8,600 | $260K |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 0.02% | New | 8,326 | $252K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 8,200 | $248K |
| Edmond DE Rothschild Holding S.A. | 0.00% | New | 7,500 | $227K |
| Public Employees Retirement System of Ohio | 0.00% | New | 6,997 | $212K |
| Balyasny Asset Management L.P. | 0.00% | Reduce -86.3% | 6,917 | $209K |
| American Century Companies Inc. | 0.00% | New | 6,865 | $208K |
| SummitTX Capital, L.P. | 0.01% | New | 6,736 | $204K |
| Wealthcare Advisory Partners LLC | 0.00% | New | 6,666 | $202K |
| Picton Mahoney Asset Management | 0.00% | New | 6,210 | $188K |
| Royal Bank of Canada | 0.00% | Add +422.7% | 4,291 | $130K |
| Simplex Trading, LLC | 0.00% | Add +378.7% | 3,983 | $120K |
| Barclays PLC | 0.00% | Reduce -68.2% | 3,177 | $96K |
| Legal & General Group Plc | 0.00% | Add +129.7% | 2,297 | $69K |
| Russell Investments Group, Ltd. | 0.00% | New | 1,995 | $60K |
| Wells Fargo & Company | 0.00% | Add +36.1% | 1,770 | $54K |
| Amalgamated Bank | 0.00% | New | 1,463 | $44K |
| California State Teachers Retirement System | 0.00% | New | 1,306 | $40K |
| SBI Securities Co., Ltd. | 0.00% | Add +676.0% | 1,226 | $37K |
| BNP Paribas Financial Markets | 0.00% | New | 1,200 | $36K |
| Bokf, NA | 0.00% | New | 1,131 | $34K |
| MetLife Investment Management, LLC | 0.00% | New | 899 | $27K |
| PNC Financial Services Group, Inc. | 0.00% | Add +327.5% | 855 | $26K |
| Cwm, LLC | 0.00% | Add +418.7% | 778 | $24K |
| Sterling Capital Management LLC | 0.00% | New | 714 | $22K |
| Comerica Bank | 0.00% | New | 662 | $20K |
| Nomura Asset Management Co. Ltd. | 0.00% | No change | 562 | $17K |
| Osaic Holdings, Inc. | 0.00% | Reduce -55.0% | 450 | $17K |
| STRS Ohio | 0.00% | New | 536 | $16K |
| Brown Brothers Harriman & Co. | 0.00% | New | 344 | $10K |
| Arax Advisory Partners | 0.00% | Add +1042.1% | 217 | $7K |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 208 | $6K |
| Ascentis Wealth Management, LLC | 0.00% | No change | 200 | $6K |
| NewEdge Advisors, LLC | 0.00% | No change | 200 | $6K |
| Jones Financial Companies LLLP | 0.00% | New | 140 | $4K |
| Financial Management Professionals, Inc. | 0.00% | Add +255.0% | 71 | $2K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -98.9% | 23 | $696 |
| J.Safra Asset Management Corp | 0.00% | New | 21 | $635 |
| MassMutual Private Wealth & Trust, FSB | 0.00% | New | 5 | $151 |
| Cedar Mountain Advisors, LLC | 0.00% | No change | 5 | $151 |
| Tortoise Investment Management, LLC | 0.00% | New | 1 | $30 |
| Global Retirement Partners, LLC | 0.00% | New | 1 | $30 |
"% of holder's portfolio" is CAI's weight in each manager's 13F, not the share of Caris Life Sciences Inc. the manager owns.