Esperion TherapeuticsESPR
13F holders, Q4 2025 (December 31)201holders +12
39new positions
27sold out
5famous investors
$3.70avg. 13F price*
At the end of Q4 2025, 201 institutions reported holding Esperion Therapeutics Inc. (ESPR) in their 13F filings, up 12 from Q3 2025. 39 opened new positions and 27 sold out. The largest holders were BlackRock, Inc. ($65.4M), Vanguard Group Inc. ($55.3M) and Two Seas Capital LP ($44.0M). 5 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Esperion Therapeutics Inc.
- CUSIP
- 29664W105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 39 | $47.7M |
| Exits | 27 | $11.0M |
All 13F filers, Q3 2025 → Q4 2025: 54,864,521 shares bought and 11,431,766 shares sold, net +43,432,755 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 201 holders
| BlackRock, Inc. | 0.00% | Add +19.2% | 17,682,201 | $65.4M |
| Vanguard Group Inc. | 0.00% | Add +23.6% | 14,945,454 | $55.3M |
| Two Seas Capital LP | 2.58% | Add +22.1% | 11,902,521 | $44.0M |
| Wasatch Advisors LP | 0.21% | Add +33.8% | 9,445,759 | $34.9M |
| D. E. Shaw & Co. | 0.02% | Add +3208.9% | 6,903,483 | $25.5M |
| Orbimed Advisors LLC | 0.45% | New | 5,965,498 | $22.1M |
| State Street Corp. | 0.00% | Add +32.4% | 5,930,296 | $21.9M |
| Geode Capital Management, LLC | 0.00% | Add +20.8% | 5,737,651 | $21.2M |
| Marshall Wace, LLP | 0.02% | Add +117.0% | 5,471,611 | $20.2M |
| Two Sigma Investments, LP | 0.03% | Add +111.8% | 4,742,082 | $17.5M |
| PenderFund Capital Management Ltd. | 6.24% | Reduce -34.2% | 4,391,926 | $16.3M |
| AIGH Capital Management LLC | 4.38% | Add +33.3% | 4,000,000 | $14.8M |
| Millennium Management | 0.01% | Add +303.4% | 3,932,274 | $14.5M |
| Eversept Partners, LP | 0.80% | New | 3,851,133 | $14.2M |
| Nuveen, LLC | 0.00% | Reduce -2.7% | 3,612,113 | $13.4M |
| Royce & Associates LP | 0.14% | Add +57.0% | 3,601,523 | $13.3M |
| Morgan Stanley | 0.00% | Reduce -13.3% | 3,514,227 | $13.0M |
| Two Sigma Advisers, LP | 0.03% | Add +83.7% | 3,505,200 | $13.0M |
| Goldman Sachs Group Inc. | 0.00% | Add +66.7% | 2,848,216 | $10.5M |
| Renaissance Technologies | 0.01% | Add +183.6% | 2,194,600 | $8.1M |
| Jones Financial Companies LLLP | 0.00% | Add +167721.5% | 2,094,412 | $7.7M |
| Northern Trust Corp. | 0.00% | Add +8.0% | 1,995,706 | $7.4M |
| Walleye Capital LLC | 0.04% | Add +391.6% | 1,569,216 | $5.8M |
| Velan Capital Investment Management LP | 2.60% | New | 1,210,000 | $4.5M |
| Voleon Capital Management LP | 0.09% | Add +455.3% | 1,154,390 | $4.3M |
| Jane Street Group, LLC | 0.00% | Reduce -44.7% | 1,080,736 | $4.0M |
| Deutsche Bank AG | 0.00% | Add +805.4% | 1,072,203 | $4.0M |
| JPMorgan Chase & Co. | 0.00% | Add +2.1% | 965,059 | $3.6M |
| Susquehanna International Group, LLP | 0.00% | Reduce -1.9% | 935,919 | $3.5M |
| Invesco Ltd. | 0.00% | Add +23.4% | 765,118 | $2.8M |
| Citadel Advisors | 0.00% | Reduce -51.0% | 750,103 | $2.8M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +22.0% | 715,326 | $2.6M |
| Bank of America Corp. | 0.00% | Add +128.8% | 696,790 | $2.6M |
| Wellington Management Group LLP | 0.00% | Reduce -5.9% | 641,178 | $2.4M |
| Victory Capital Management Inc. | 0.00% | Add +39.6% | 595,982 | $2.2M |
| Bank of New York Mellon Corp | 0.00% | Add +18.6% | 549,094 | $2.0M |
| Barclays PLC | 0.00% | Add +32.1% | 443,339 | $1.6M |
| Burkehill Global Management, LP | 0.10% | New | 400,000 | $1.5M |
| Summit Wealth Group, LLC | 0.29% | Add +5.5% | 340,606 | $1.3M |
| Mackenzie Financial Corp. | 0.00% | Add +23.5% | 336,992 | $1.2M |
| UBS Group AG | 0.00% | Reduce -74.9% | 313,353 | $1.2M |
| AQR Capital Management | 0.00% | Add +2.0% | 290,514 | $1.1M |
| Mariner, LLC | 0.00% | Reduce -7.9% | 278,661 | $1.0M |
| Principal Financial Group Inc. | 0.00% | Add +45.4% | 276,292 | $1.0M |
| Rhumbline Advisers | 0.00% | Reduce -2.8% | 269,738 | $998K |
| Wells Fargo & Company | 0.00% | Add +80.5% | 263,188 | $974K |
| Alliancebernstein L.P. | 0.00% | Add +23.6% | 261,760 | $969K |
| Quadrature Capital Ltd | 0.01% | New | 259,563 | $960K |
| Quantbot Technologies LP | 0.03% | Add +36.0% | 244,292 | $904K |
| HRT Financial LP | 0.00% | Add +51.6% | 239,360 | $885K |
| Headlands Technologies LLC | 0.07% | Add +129.7% | 221,088 | $818K |
| BNP Paribas Financial Markets | 0.00% | Reduce -40.2% | 213,665 | $791K |
| T. Rowe Price Associates Inc. | 0.00% | Add +23.4% | 188,639 | $698K |
| Virtus Investment Advisers, LLC | 0.18% | New | 177,508 | $657K |
| UMB Bank, n.a. | 0.01% | No change | 170,000 | $629K |
| Brevan Howard Capital Management LP | 0.01% | Reduce -35.8% | 169,030 | $625K |
| Diametric Capital, LP | 0.17% | Reduce -28.4% | 169,006 | $625K |
| XTX Topco Ltd | 0.02% | New | 161,974 | $599K |
| Graham Capital Management, L.P. | 0.03% | Add +968.9% | 161,557 | $598K |
| MetLife Investment Management, LLC | 0.00% | Add +21.8% | 129,735 | $480K |
| Woodline Partners LP | 0.00% | Reduce -66.8% | 127,030 | $470K |
| Citigroup Inc. | 0.00% | Add +112.0% | 121,094 | $448K |
| Creative Planning | 0.00% | Add +135.1% | 117,367 | $434K |
| Polen Capital Management LLC | 0.00% | New | 116,292 | $430K |
| HighTower Advisors, LLC | 0.00% | Reduce -5.1% | 113,899 | $421K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +15.8% | 108,627 | $402K |
| Summit Financial, LLC | 0.01% | Add +8.7% | 107,263 | $397K |
| Tocqueville Asset Management L.P. | 0.01% | Add +17.6% | 107,000 | $396K |
| Parallel Advisors, LLC | 0.01% | Reduce -9.2% | 106,684 | $395K |
| Intech Investment Management LLC | 0.00% | Add +5.5% | 104,938 | $388K |
| Round Rock Advisors LLC | 0.06% | New | 101,553 | $376K |
| Advent Capital Management | 0.55% | Add +12.5% | 90,000 | $333K |
| Osaic Holdings, Inc. | 0.00% | Add +6.2% | 86,443 | $320K |
| FMR LLC | 0.00% | Add +27.0% | 80,398 | $297K |
| Raymond James Financial Inc. | 0.00% | Add +26.9% | 76,227 | $282K |
| Sei Investments Co. | 0.00% | Reduce -2.3% | 75,992 | $281K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 75,238 | $278K |
| Integrated Quantitative Investments LLC | 0.06% | New | 72,249 | $267K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +0.3% | 70,040 | $259K |
| Profund Advisors LLC | 0.01% | Add +65.2% | 69,712 | $258K |
| Capital Advisors Wealth Management, LLC | 0.03% | Add +58.8% | 67,555 | $250K |
| nVerses Capital, LLC | 0.56% | — | 67,450 | $250K |
| Lighthouse Investment Partners, LLC | 0.01% | New | 66,890 | $247K |
| New York State Common Retirement Fund | 0.00% | Add +103.5% | 63,900 | $236K |
| State of Wyoming | 0.03% | New | 63,352 | $234K |
| Rafferty Asset Management, LLC | 0.00% | Add +116.1% | 61,045 | $226K |
| Pinnacle Associates Ltd. | 0.00% | Reduce -0.9% | 60,581 | $224K |
| Savvy Advisors, Inc. | 0.01% | New | 60,000 | $222K |
| WINTON GROUP Ltd | 0.01% | Reduce -17.7% | 58,345 | $216K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 57,618 | $213K |
| ProShare Advisors LLC | 0.00% | Add +29.0% | 53,315 | $197K |
| Los Angeles Capital Management LLC | 0.00% | Add +40.6% | 67,751 | $192K |
| Bank of Montreal | 0.00% | Add +24.0% | 51,923 | $192K |
| Versor Investments LP | 0.03% | New | 51,800 | $192K |
| SG Americas Securities, LLC | 0.00% | Reduce -50.8% | 50,997 | $189K |
| Act Capital Management, LLC | 0.14% | — | 47,500 | $176K |
| Eaton Financial Holdings Company, LLC | 0.05% | Add +9.4% | 46,595 | $172K |
| Boomfish Wealth Group, LLC | 0.09% | No change | 45,306 | $168K |
| North Star Investment Management Corp. | 0.01% | Add +28.6% | 45,000 | $167K |
| Voya Investment Management LLC | 0.00% | Add +6.7% | 40,523 | $150K |
"% of holder's portfolio" is ESPR's weight in each manager's 13F, not the share of Esperion Therapeutics Inc. the manager owns.