Guardant HealthGH
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 498 institutions reported holding Guardant Health Inc. (GH) in their 13F filings, up 103 from Q3 2025. 121 opened new positions and 31 sold out. The largest holders were Vanguard Group Inc. ($1.2B), BlackRock, Inc. ($1.2B) and T. Rowe Price Associates Inc. ($575.7M). 9 famous investors held it, including Cathie Wood (0.5% of ARK Investment Management's portfolio), Steve Cohen (0.3% of Point72 Asset Management's portfolio) and Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio).
- Company
- Guardant Health Inc.
- CUSIP
- 40131M109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 121 | $401.6M |
| Exits | 31 | $65.4M |
All 13F filers, Q3 2025 → Q4 2025: 22,042,721 shares bought and 15,157,635 shares sold, net +6,885,086 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 498 holders
| Vanguard Group Inc. | 0.02% | Add +2.1% | 12,160,768 | $1.2B |
| BlackRock, Inc. | 0.02% | Reduce -1.0% | 11,317,714 | $1.2B |
| T. Rowe Price Associates Inc. | 0.06% | Add +33.5% | 5,636,078 | $575.7M |
| Invesco Ltd. | 0.05% | Add +7.8% | 5,315,934 | $543.0M |
| Baillie Gifford & Co. | 0.42% | Reduce -4.6% | 4,890,026 | $499.5M |
| Capital International Investors | 0.06% | Reduce -24.8% | 3,528,656 | $360.4M |
| Franklin Resources Inc. | 0.09% | Add +14.9% | 3,361,547 | $343.3M |
| Geode Capital Management, LLC | 0.02% | Add +9.4% | 3,213,657 | $328.3M |
| Deep Track Capital, LP | 6.52% | Reduce -32.6% | 2,800,000 | $286.0M |
| State Street Corp. | 0.01% | Add +0.3% | 2,795,727 | $285.6M |
| Goldman Sachs Group Inc. | 0.04% | Add +74.5% | 2,627,709 | $268.4M |
| Eventide Asset Management, LLC | 4.01% | Reduce -24.4% | 2,511,091 | $256.5M |
| Fuller & Thaler Asset Management, Inc. | 0.84% | Add +3.0% | 2,441,730 | $249.4M |
| FMR LLC | 0.01% | Add +190.7% | 2,396,433 | $244.8M |
| Two Sigma Advisers, LP | 0.47% | Add +12.8% | 2,382,300 | $243.3M |
| Two Sigma Investments, LP | 0.35% | Add +20.4% | 2,171,903 | $221.8M |
| Driehaus Capital Management LLC | 1.49% | Reduce -0.4% | 2,143,193 | $218.9M |
| Federated Hermes, Inc. | 0.35% | Add +14.4% | 2,031,562 | $207.5M |
| Lord, Abbett & Co. LLC | 0.65% | Add +30.5% | 1,988,983 | $203.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.04% | Reduce -15.3% | 1,915,581 | $195.7M |
| Alliancebernstein L.P. | 0.06% | Add +1262.7% | 1,901,308 | $194.2M |
| UBS Group AG | 0.03% | Add +17.4% | 1,710,169 | $174.7M |
| Point72 Asset Management | 0.25% | Add +1363.8% | 1,499,169 | $153.1M |
| RTW Investments, LP | 1.52% | No change | 1,481,033 | $151.3M |
| Charles Schwab Investment Management Inc. | 0.02% | Add +3.0% | 1,457,676 | $148.9M |
| Bank of New York Mellon Corp | 0.02% | Add +43.4% | 1,366,157 | $139.5M |
| Alyeska Investment Group, L.P. | 0.39% | Reduce -26.6% | 1,343,654 | $137.2M |
| Norges Bank | 0.01% | — | 1,258,072 | $128.5M |
| Jennison Associates LLC | 0.07% | Reduce -20.5% | 1,170,337 | $119.5M |
| Morgan Stanley | 0.01% | Add +17.5% | 1,154,299 | $117.9M |
| Northern Trust Corp. | 0.01% | Reduce -4.5% | 1,102,791 | $112.6M |
| Erste Asset Management GmbH | 0.90% | Add +48.3% | 1,045,917 | $106.8M |
| Temasek Holdings (Private) Ltd | 0.34% | No change | 1,044,097 | $106.6M |
| Bank of America Corp. | 0.01% | Add +16.4% | 1,017,646 | $103.9M |
| Hood River Capital Management LLC | 1.10% | Add +280.9% | 978,515 | $99.9M |
| Cadian Capital Management, LP | 6.81% | Reduce -56.9% | 922,628 | $94.2M |
| Emerald Advisers, LLC | 2.71% | Reduce -1.3% | 861,824 | $88.0M |
| Summit Partners Public Asset Management, LLC | 2.45% | Add +674.5% | 851,958 | $87.0M |
| Ameriprise Financial Inc. | 0.02% | Add +148.0% | 762,595 | $77.9M |
| ARK Investment Management | 0.47% | Reduce -13.0% | 691,647 | $70.6M |
| Sumitomo Mitsui Trust Group, Inc. | 0.04% | Reduce -15.1% | 640,505 | $65.4M |
| Amova Asset Management Americas, Inc. | 0.76% | Reduce -15.1% | 640,295 | $65.4M |
| Manufacturers Life Insurance Company, The | 0.05% | Add +0.2% | 635,935 | $64.8M |
| BNP Paribas Financial Markets | 0.04% | Add +981.5% | 624,776 | $63.8M |
| D. E. Shaw & Co. | 0.05% | Add +1768.4% | 623,057 | $63.6M |
| Allspring Global Investments Holdings, LLC | 0.10% | Reduce -1.9% | 618,599 | $62.9M |
| Renaissance Technologies | 0.10% | Add +13.3% | 602,300 | $61.5M |
| Fred Alger Management, LLC | 0.24% | Reduce -7.7% | 589,656 | $60.2M |
| Millennium Management | 0.04% | Reduce -33.5% | 583,807 | $59.6M |
| Citadel Advisors | 0.04% | Add +85.3% | 564,342 | $57.6M |
| Westfield Capital Management Co. LP | 0.23% | New | 539,190 | $55.1M |
| Emerald Mutual Fund Advisers Trust | 2.61% | Reduce -5.8% | 523,932 | $53.5M |
| Jane Street Group, LLC | 0.06% | Add +567.2% | 513,620 | $52.5M |
| Balyasny Asset Management L.P. | 0.10% | Reduce -5.2% | 505,608 | $51.6M |
| Aristotle Atlantic Partners, LLC | 2.31% | Reduce -46.5% | 494,386 | $50.5M |
| Nuveen, LLC | 0.01% | Add +4.1% | 473,451 | $48.4M |
| Adage Capital Partners Gp, L.L.C. | 0.07% | Add +205.6% | 464,905 | $47.5M |
| Jupiter Asset Management Ltd. | 0.34% | Add +102.7% | 421,328 | $43.0M |
| Wellington Management Group LLP | 0.01% | Reduce -87.5% | 406,519 | $41.5M |
| Casdin Capital, LLC | 2.41% | Add +280.0% | 380,000 | $38.8M |
| Victory Capital Management Inc. | 0.02% | Reduce -20.5% | 377,045 | $38.5M |
| Blue Water Life Science Advisors, LP | 22.76% | Reduce -12.5% | 355,047 | $36.3M |
| Deutsche Bank AG | 0.01% | Add +0.2% | 336,428 | $34.4M |
| Barclays PLC | 0.01% | Add +21.2% | 336,274 | $34.3M |
| PBU - The Pension Fund of Early Childhood & Youth Educators | 0.50% | — | 335,854 | $34.3M |
| Voya Investment Management LLC | 0.04% | Reduce -7.3% | 330,429 | $33.8M |
| Raymond James Financial Inc. | 0.01% | Reduce -0.4% | 328,632 | $33.2M |
| Dimensional Fund Advisors LP | 0.01% | Add +371.5% | 306,553 | $31.3M |
| Man Group plc | 0.06% | Reduce -60.6% | 295,804 | $30.2M |
| First Light Asset Management, LLC | 2.30% | Add +5.3% | 294,751 | $30.1M |
| Artisan Partners Limited Partnership | 0.05% | New | 290,352 | $29.7M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.05% | Reduce -4.6% | 287,454 | $29.2M |
| Eagle Health Investments LP | 6.38% | No change | 284,100 | $29.0M |
| Styrax Capital, LP | 2.20% | New | 281,589 | $28.8M |
| Trexquant Investment LP | 0.25% | Reduce -28.8% | 274,039 | $28.0M |
| First Turn Management, LLC | 3.17% | New | 271,685 | $27.7M |
| JPMorgan Chase & Co. | 0.00% | Reduce -45.1% | 271,039 | $27.7M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.07% | Add +83.3% | 266,492 | $27.2M |
| Sei Investments Co. | 0.03% | Add +30.1% | 261,942 | $26.8M |
| Walleye Capital LLC | 0.16% | Add +269.7% | 254,302 | $26.0M |
| Segall Bryant & Hamill, LLC | 0.34% | Reduce -19.9% | 244,266 | $24.9M |
| Massachusetts Financial Services Co. | 0.01% | Reduce -21.7% | 237,481 | $24.3M |
| Sicart Associates LLC | 6.18% | Reduce -0.8% | 228,203 | $23.3M |
| Swiss National Bank | 0.01% | Add +2.4% | 221,300 | $22.6M |
| California Public Employees Retirement System | 0.01% | Add +4.0% | 215,092 | $22.0M |
| Wells Fargo & Company | 0.00% | Add +87.9% | 214,177 | $21.9M |
| Nomura Asset Management International Inc. | 0.03% | — | 212,947 | $21.8M |
| Russell Investments Group, Ltd. | 0.02% | Add +8.3% | 211,392 | $21.6M |
| Rathbones Group PLC | 0.08% | Add +2.5% | 205,113 | $21.0M |
| Axiom Investors LLC | 0.18% | New | 203,642 | $20.8M |
| Citigroup Inc. | 0.01% | Add +883.1% | 188,888 | $19.3M |
| TD Asset Management Inc | 0.01% | Reduce -4.1% | 181,048 | $18.5M |
| First Trust Advisors LP | 0.01% | Reduce -3.5% | 179,731 | $18.4M |
| Marshall Wace, LLP | 0.02% | Reduce -29.1% | 171,206 | $17.5M |
| Pictet Asset Management Holding SA | 0.02% | Reduce -35.0% | 166,384 | $16.9M |
| Castleark Management LLC | 0.49% | Add +3.1% | 165,043 | $16.9M |
| Perceptive Advisors LLC | 0.30% | New | 160,000 | $16.3M |
| Picton Mahoney Asset Management | 0.18% | New | 159,029 | $16.2M |
| Granite Investment Partners, LLC | 0.96% | Reduce -14.6% | 158,199 | $16.2M |
| Polar Capital Holdings Plc | 0.07% | New | 157,485 | $16.1M |
"% of holder's portfolio" is GH's weight in each manager's 13F, not the share of Guardant Health Inc. the manager owns.