Inspire Medical SystemsINSP
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 343 institutions reported holding Inspire Medical Systems Inc. (INSP) in their 13F filings, up 18 from Q3 2025. 76 opened new positions and 69 sold out. The largest holders were BlackRock, Inc. ($327.5M), Vanguard Group Inc. ($272.4M) and Wellington Management Group LLP ($203.9M). 9 famous investors held it, including David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio), Ron Baron (0.1% of Baron Capital (BAMCO)'s portfolio) and Paul Tudor Jones (0.1% of Tudor Investment Corporation's portfolio).
- Company
- Inspire Medical Systems Inc.
- CUSIP
- 457730109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 76 | $425.1M |
| Exits | 69 | $195.0M |
All 13F filers, Q3 2025 → Q4 2025: 10,941,520 shares bought and 8,284,207 shares sold, net +2,657,313 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 343 holders
| BlackRock, Inc. | 0.01% | Add +0.1% | 3,550,848 | $327.5M |
| Vanguard Group Inc. | 0.00% | Reduce -1.6% | 2,953,170 | $272.4M |
| Wellington Management Group LLP | 0.04% | New | 2,211,091 | $203.9M |
| Deerfield Management Company, L.P. | 2.03% | Add +43.7% | 1,505,872 | $138.9M |
| Morgan Stanley | 0.01% | Add +179.6% | 1,259,762 | $116.2M |
| D. E. Shaw & Co. | 0.09% | Add +237.8% | 1,212,162 | $111.8M |
| William Blair Investment Management, LLC | 0.30% | Reduce -10.5% | 1,161,285 | $107.1M |
| State Street Corp. | 0.00% | Reduce -6.2% | 918,504 | $84.7M |
| Artisan Partners Limited Partnership | 0.11% | Add +49.3% | 785,742 | $72.5M |
| Fuller & Thaler Asset Management, Inc. | 0.21% | New | 668,099 | $61.6M |
| Janus Henderson Group PLC | 0.02% | Reduce -15.7% | 562,331 | $51.9M |
| Braidwell LP | 1.91% | Reduce -38.8% | 540,890 | $49.9M |
| Marshall Wace, LLP | 0.05% | Add +295.5% | 531,079 | $49.0M |
| Deutsche Bank AG | 0.02% | Add +7090.0% | 516,816 | $47.7M |
| Citadel Advisors | 0.03% | Reduce -70.8% | 511,318 | $47.2M |
| Geode Capital Management, LLC | 0.00% | Reduce -2.6% | 491,750 | $45.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Reduce -44.4% | 463,316 | $42.7M |
| Aberdeen Group plc | 0.07% | Add +16.3% | 460,901 | $42.5M |
| BNP Paribas Financial Markets | 0.03% | Reduce -12.9% | 454,810 | $41.9M |
| Eventide Asset Management, LLC | 0.63% | Add +71.5% | 440,205 | $40.6M |
| UBS Group AG | 0.01% | Reduce -12.1% | 411,329 | $37.9M |
| Renaissance Technologies | 0.06% | Add +165.0% | 410,768 | $37.9M |
| Amundi | 0.01% | Add +42.9% | 364,622 | $33.6M |
| Driehaus Capital Management LLC | 0.22% | New | 348,500 | $32.1M |
| Dimensional Fund Advisors LP | 0.01% | Reduce -0.7% | 341,397 | $31.5M |
| Baron Capital (BAMCO) | 0.08% | Add +77.6% | 337,486 | $31.1M |
| T. Rowe Price Associates Inc. | 0.00% | Add +1136.2% | 308,171 | $28.4M |
| Jefferies Financial Group Inc. | 0.24% | New | 307,588 | $28.4M |
| Soleus Capital Management, L.P. | 1.17% | Reduce -58.9% | 299,399 | $27.6M |
| Goldman Sachs Group Inc. | 0.00% | Add +8.2% | 284,885 | $26.3M |
| Jane Street Group, LLC | 0.03% | Add +288.0% | 277,199 | $25.6M |
| Jain Global LLC | 0.25% | Add +6785.3% | 268,250 | $24.7M |
| Assenagon Asset Management S.A. | 0.04% | New | 264,999 | $24.4M |
| Invesco Ltd. | 0.00% | Add +181.7% | 261,374 | $24.1M |
| Franklin Resources Inc. | 0.01% | Reduce -22.1% | 231,438 | $21.3M |
| Bank of New York Mellon Corp | 0.00% | Add +29.3% | 215,780 | $19.9M |
| Trexquant Investment LP | 0.18% | New | 213,249 | $19.7M |
| Regal Partners Ltd | 1.12% | Add +107.7% | 211,304 | $19.5M |
| Bank of America Corp. | 0.00% | Reduce -27.3% | 210,126 | $19.4M |
| Champlain Investment Partners, LLC | 0.19% | Reduce -50.1% | 203,098 | $18.7M |
| Millennium Management | 0.01% | Reduce -43.4% | 202,140 | $18.6M |
| Keybank National Association | 0.07% | Add +0.0% | 200,042 | $18.4M |
| Northern Trust Corp. | 0.00% | Add +4.0% | 197,456 | $18.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.5% | 194,155 | $17.9M |
| Voloridge Investment Management, LLC | 0.06% | Add +113.0% | 188,100 | $17.3M |
| Balyasny Asset Management L.P. | 0.03% | Reduce -69.5% | 187,226 | $17.3M |
| Nuveen, LLC | 0.00% | Add +233.2% | 159,421 | $14.7M |
| Frontier Capital Management Co. LLC | 0.14% | Reduce -12.5% | 142,007 | $13.1M |
| Ra Capital Management, L.P. | 0.13% | Add +23.6% | 141,964 | $13.1M |
| FMR LLC | 0.00% | Reduce -81.7% | 137,306 | $12.7M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.03% | Reduce -2.1% | 136,420 | $12.6M |
| Rock Springs Capital Management LP | 0.62% | Add +18.6% | 131,000 | $12.1M |
| Norges Bank | 0.00% | — | 129,570 | $12.0M |
| Principal Financial Group Inc. | 0.01% | Reduce -2.7% | 125,519 | $11.6M |
| Capital Fund Management S.A. | 0.11% | Add +68.1% | 122,706 | $11.3M |
| HRT Financial LP | 0.04% | Add +166.6% | 121,761 | $11.2M |
| Brown Capital Management LLC | 0.91% | Reduce -56.9% | 119,935 | $11.1M |
| Rheos Capital Works Inc. | 0.69% | Add +124.0% | 117,400 | $10.8M |
| Wasatch Advisors LP | 0.06% | Reduce -14.6% | 116,068 | $10.7M |
| Tudor Investment Corporation | 0.06% | New | 112,873 | $10.4M |
| Canada Pension Plan Investment Board | 0.01% | Add +166.4% | 105,500 | $9.7M |
| Bellevue Group AG | 0.18% | Add +71.8% | 100,761 | $9.3M |
| Riverbridge Partners LLC | 0.17% | Reduce -6.2% | 97,111 | $9.0M |
| Public Sector Pension Investment Board | 0.03% | Reduce -12.9% | 91,472 | $8.4M |
| Ameriprise Financial Inc. | 0.00% | Add +2.5% | 91,277 | $8.4M |
| ING Groep NV | 0.05% | Add +554.1% | 88,300 | $8.1M |
| Barclays PLC | 0.00% | Add +890.2% | 85,655 | $7.9M |
| Glenmede Trust Co. NA | 0.04% | — | 81,986 | $7.6M |
| Walleye Capital LLC | 0.04% | Reduce -39.2% | 78,217 | $7.2M |
| Arrowstreet Capital, Limited Partnership | 0.00% | New | 76,028 | $7.0M |
| Integral Health Asset Management, LLC | 0.35% | Reduce -37.5% | 75,000 | $6.9M |
| Bridgewater Associates | 0.02% | Reduce -19.4% | 71,727 | $6.6M |
| Y-Intercept (Hong Kong) Ltd | 0.15% | Reduce -28.7% | 70,635 | $6.5M |
| Legal & General Group Plc | 0.00% | Reduce -17.2% | 69,756 | $6.4M |
| New York State Common Retirement Fund | 0.01% | Add +36.9% | 68,774 | $6.3M |
| Credit Agricole S A | 0.02% | Reduce -46.0% | 67,695 | $6.2M |
| Rhumbline Advisers | 0.00% | Reduce -1.9% | 65,894 | $6.1M |
| Voleon Capital Management LP | 0.13% | Reduce -19.0% | 63,627 | $5.9M |
| Nomura Holdings Inc. | 0.02% | New | 60,950 | $5.6M |
| Two Sigma Investments, LP | 0.01% | Add +60.2% | 59,515 | $5.5M |
| Mairs & Power Inc. | 0.05% | Reduce -12.0% | 57,616 | $5.3M |
| Swiss National Bank | 0.00% | Add +2.0% | 55,500 | $5.1M |
| Nomura Asset Management International Inc. | 0.01% | — | 52,246 | $4.8M |
| Sei Investments Co. | 0.00% | Add +210.1% | 50,940 | $4.7M |
| Gotham Asset Management | 0.02% | Add +66.9% | 48,547 | $4.5M |
| Susquehanna International Group, LLP | 0.01% | Reduce -30.1% | 48,497 | $4.5M |
| Algert Global LLC | 0.07% | Add +96.9% | 46,250 | $4.3M |
| XTX Topco Ltd | 0.11% | Add +528.1% | 45,783 | $4.2M |
| JPMorgan Chase & Co. | 0.00% | Reduce -43.5% | 45,388 | $4.2M |
| Lazard Asset Management LLC | 0.01% | Reduce -49.8% | 44,981 | $4.1M |
| HSBC Holdings PLC | 0.00% | Reduce -0.5% | 43,328 | $4.0M |
| Man Group plc | 0.01% | Reduce -50.6% | 41,425 | $3.8M |
| Bank of Nova Scotia | 0.01% | Add +65.5% | 40,042 | $3.7M |
| ExodusPoint Capital Management, LP | 0.04% | Add +18.5% | 38,896 | $3.6M |
| SG Americas Securities, LLC | 0.00% | Add +395.9% | 38,449 | $3.5M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +990.1% | 38,404 | $3.5M |
| Bullseye Asset Management LLC | 1.80% | No change | 36,128 | $3.3M |
| Rhenman & Partners Asset Management AB | 0.31% | Reduce -41.3% | 35,800 | $3.3M |
| Citigroup Inc. | 0.00% | Reduce -18.1% | 34,672 | $3.2M |
| EFG International AG | 0.06% | — | 33,813 | $3.1M |
"% of holder's portfolio" is INSP's weight in each manager's 13F, not the share of Inspire Medical Systems Inc. the manager owns.