| Bain Capital Investors LLC | 12.01% | New | 26,255,581 | $578.4M |
| Bain Capital Life Sciences Investors, LLC | 29.62% | New | 22,583,268 | $497.5M |
| RTW Investments, LP | 2.03% | New | 10,776,820 | $237.4M |
| Canada Pension Plan Investment Board | 0.09% | New | 7,304,688 | $160.9M |
| Atlas Venture Life Science Advisors, LLC | 12.93% | New | 5,171,282 | $113.9M |
| FMR LLC | 0.00% | New | 3,970,865 | $87.5M |
| BlackRock, Inc. | 0.00% | New | 3,928,604 | $86.5M |
| T. Rowe Price Associates Inc. | 0.01% | New | 3,534,410 | $77.9M |
| Citadel Advisors | 0.04% | New | 3,240,787 | $71.4M |
| Adage Capital Partners Gp, L.L.C. | 0.10% | New | 3,208,286 | $70.7M |
| Wellington Management Group LLP | 0.01% | New | 2,919,110 | $64.3M |
| Royalty Pharma Sub-Manager, LLC | 22.36% | New | 2,455,357 | $54.1M |
| Siren, L.L.C. | 0.99% | New | 2,214,286 | $48.8M |
| Vanguard Capital Management LLC | 0.00% | New | 1,693,958 | $37.3M |
| Vanguard Portfolio Management LLC | 0.00% | New | 1,652,507 | $36.4M |
| Geode Capital Management, LLC | 0.00% | New | 1,133,115 | $25.0M |
| Frazier Life Sciences Management, L.P. | 0.53% | New | 1,100,000 | $24.2M |
| Farallon Capital Management, L.L.C. | 0.14% | New | 1,100,000 | $24.2M |
| Trails Edge Capital Partners, LP | 3.44% | New | 984,786 | $21.7M |
| UBS Group AG | 0.00% | New | 972,683 | $21.4M |
| Jupiter Topco LLC | 0.01% | — | 970,857 | $21.3M |
| State Street Corp. | 0.00% | New | 868,160 | $19.1M |
| Ameriprise Financial Inc. | 0.00% | New | 821,331 | $18.1M |
| Deep Track Capital, LP | 0.23% | New | 700,000 | $15.4M |
| Eventide Asset Management, LLC | 0.18% | New | 616,720 | $13.6M |
| Vestal Point Capital, LP | 0.30% | New | 575,000 | $12.7M |
| Cormorant Asset Management, LP | 0.62% | New | 550,000 | $12.1M |
| Catalio Capital Management, LP | 1.94% | New | 468,750 | $10.3M |
| Federated Hermes, Inc. | 0.01% | New | 434,069 | $9.6M |
| Goldman Sachs Group Inc. | 0.00% | New | 421,034 | $9.3M |
| Franklin Resources Inc. | 0.00% | New | 400,023 | $8.8M |
| Charles Schwab Investment Management Inc. | 0.00% | New | 362,910 | $8.0M |
| Northern Trust Corp. | 0.00% | New | 354,431 | $7.8M |
| Vanguard Fiduciary Trust Co. | 0.00% | New | 290,128 | $6.4M |
| Seven Grand Managers, LLC | 0.16% | New | 175,000 | $3.9M |
| Balyasny Asset Management L.P. | 0.01% | New | 154,838 | $3.4M |
| Exchange Traded Concepts, LLC | 0.02% | New | 152,501 | $3.4M |
| Manufacturers Life Insurance Company, The | 0.00% | New | 149,817 | $3.3M |
| TD Asset Management Inc | 0.00% | New | 147,698 | $3.3M |
| Nantahala Capital Management, LLC | 0.19% | New | 140,000 | $3.1M |
| a16z Capital Management, L.L.C. | 0.02% | New | 140,000 | $3.1M |
| Aberdeen Group plc | 0.00% | New | 140,000 | $3.1M |
| Bank of New York Mellon Corp | 0.00% | New | 138,399 | $3.0M |
| Alps Advisors Inc. | 0.01% | New | 131,000 | $2.9M |
| Nuveen, LLC | 0.00% | New | 88,796 | $2.0M |
| Avidity Partners Management LP | 0.28% | New | 80,000 | $1.8M |
| Ghisallo Capital Management LLC | 0.04% | New | 75,000 | $1.7M |
| Rock Springs Capital Management LP | 0.07% | New | 65,000 | $1.4M |
| Alliancebernstein L.P. | 0.00% | New | 61,090 | $1.3M |
| Rhumbline Advisers | 0.00% | New | 58,387 | $1.3M |
| Morgan Stanley | 0.00% | New | 57,786 | $1.3M |
| Bank of America Corp. | 0.00% | New | 56,510 | $1.2M |
| Russell Investments Group, Ltd. | 0.00% | New | 53,317 | $1.2M |
| XTX Topco Ltd | 0.01% | New | 49,224 | $1.1M |
| Lazard Asset Management LLC | 0.00% | New | 48,391 | $1.1M |
| Tudor Investment Corporation | 0.00% | New | 48,050 | $1.1M |
| Deutsche Bank AG | 0.00% | New | 45,648 | $1.0M |
| Squarepoint Ops LLC | 0.00% | New | 45,062 | $993K |
| Wells Fargo & Company | 0.00% | New | 43,120 | $950K |
| Foresite Capital Management VI LLC | 0.13% | New | 37,500 | $826K |
| Cibc World Market Inc. | 0.00% | New | 35,476 | $782K |
| JPMorgan Chase & Co. | 0.00% | New | 31,308 | $724K |
| Susquehanna International Group, LLP | 0.00% | New | 32,609 | $718K |
| Invesco Ltd. | 0.00% | New | 28,389 | $625K |
| MetLife Investment Management, LLC | 0.00% | New | 27,326 | $602K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | New | 22,951 | $506K |
| Citigroup Inc. | 0.00% | New | 21,547 | $475K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | New | 21,171 | $466K |
| Soros Fund Management | 0.01% | New | 20,000 | $441K |
| Quadrature Capital Ltd | 0.00% | New | 19,200 | $423K |
| D. E. Shaw & Co. | 0.00% | New | 17,500 | $386K |
| Vanguard Global Advisers, LLC | 0.00% | New | 17,428 | $384K |
| New York State Common Retirement Fund | 0.00% | New | 16,200 | $357K |
| Harbour Capital Advisors, LLC | 0.06% | New | 16,570 | $343K |
| Tema ETFs LLC | 0.01% | New | 14,039 | $309K |
| Tidal Investments LLC | 0.00% | New | 14,039 | $309K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | New | 13,618 | $300K |
| Barclays PLC | 0.00% | New | 10,331 | $228K |
| Victory Capital Management Inc. | 0.00% | New | 10,306 | $227K |
| Hudson Bay Capital Management LP | 0.00% | New | 10,050 | $221K |
| Gabelli Funds LLC | 0.00% | New | 10,000 | $220K |
| Legal & General Group Plc | 0.00% | New | 9,048 | $199K |
| STRS Ohio | 0.00% | New | 9,000 | $198K |
| BNP Paribas Financial Markets | 0.00% | New | 7,000 | $154K |
| US Bancorp \de | 0.00% | New | 5,013 | $110K |
| Penserra Capital Management LLC | 0.00% | New | 4,864 | $107K |
| Ameritas Investment Partners, Inc. | 0.00% | New | 4,190 | $92K |
| Diadema Partners LP | 0.03% | New | 3,621 | $80K |
| Tower Research Capital LLC (TRC) | 0.00% | New | 3,289 | $72K |
| Royal Bank of Canada | 0.00% | New | 2,924 | $65K |
| PNC Financial Services Group, Inc. | 0.00% | New | 2,642 | $58K |
| Persistent Asset Partners Ltd | 0.01% | New | 1,765 | $39K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 1,150 | $25K |
| Nisa Investment Advisors, LLC | 0.00% | New | 871 | $19K |
| California State Teachers Retirement System | 0.00% | New | 636 | $14K |
| Sterling Capital Management LLC | 0.00% | New | 402 | $9K |
| Fortitude Family Office, LLC | 0.00% | New | 32 | $705 |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 20 | $441 |
| Jones Financial Companies LLLP | 0.00% | New | 15 | $312 |
| SBI Securities Co., Ltd. | 0.00% | New | 1 | $22 |