Diadema Partners LP

In its 13F for Q2 2026 (holdings as of June 30, 2026, filed August 14, 2026), Diadema Partners LP reported 77 stock positions worth $264.6 million. Its top holding was United Therapeutics (UTHR) at 10.9% of the portfolio, followed by Revolution Medicines (RVMD, 9.9%) and Abivax SA-ADR (ABVX, 8.2%). Compared with Q1 2026, it opened 29 new positions, sold out of 38, added to 21 and reduced 19. The biggest buy was Revolution Medicines (RVMD, shares +72%) and the biggest sale an exit from Bridgebio Pharma Inc. (bbio 1.75 03/01/31).

Most Recent 13F
Q2 2026
Location
MORRISTOWN, NJ
CIK
0002026172
Portfolio Value
$264.6M (Q2 2026)
SEC Filing
0001892688-26-000119 ↗ filed Aug 14, 2026

Holdings Value

0$100.0M$200.0M$300.0M Q4 2024: $88.7M Q4 2024 Q1 2025: $125.1M Q1 2025 Q2 2025: $160.8M Q2 2025 Q3 2025: $143.6M Q3 2025 Q4 2025: $167.9M Q4 2025 Q1 2026: $242.2M Q1 2026 Q2 2026: $264.6M $264.6M Q2 2026

Holdings 77 stocks · $264.6M

UTHR United Therapeutics Corp. 10.85% 52,989 $28.7M Add +94.1%
RVMD Revolution Medicines Inc. 9.86% 139,218 $26.1M Add +72.2%
ABVX Abivax SA-ADR 8.16% 163,644 $21.6M Add +115.5%
COGT Cogent Biosciences Inc. 7.22% 493,664 $19.1M Add +53.0%
BMRN Biomarin Pharmaceutical Inc. 6.77% 312,846 $17.9M Add +111.1%
VKTX Viking Therapeutics Inc. 6.51% 441,808 $17.2M Reduce -15.9%
EWTX Edgewise Therapeutics Inc. 4.18% 272,214 $11.1M New
KOD Kodiak Sciences Inc. 3.21% 218,117 $8.5M Add +13.0%
IMCR Immunocore Holdings PLC-ADR 3.06% 254,863 $8.1M Add +31.9%
FDMT 4D Molecular Therapeutics Inc. 2.87% 571,107 $7.6M New
RCUS Arcus Biosciences Inc. 2.61% 223,810 $6.9M Reduce -6.0%
JNJ Johnson & Johnson 2.11% 22,000 $5.6M Reduce -59.1%
NVO Novo-Nordisk A/S-Spons ADR 1.82% 100,000 $4.8M Add +586.0%
CRVS Corvus Pharmaceuticals Inc. 1.66% 294,811 $4.4M Add +20.4%
RLAY Relay Therapeutics Inc. 1.63% 230,677 $4.3M New
ZYME Zymeworks Inc. 1.40% 142,132 $3.7M No change
BIOA Bioage Labs Inc. 1.36% 146,334 $3.6M Add +143.9%
TSHA Taysha Gene Therapies Inc. 1.35% 522,619 $3.6M New
NRIX Nurix Therapeutics Inc. 1.11% 121,539 $2.9M New
CRBP Corbus Pharmaceuticals Holdi 1.07% 301,264 $2.8M Reduce -31.5%
INDV Indivior Pharmaceuticals Inc. 1.05% 67,512 $2.8M Reduce -5.4%
IVA Inventiva SA - ADR 1.03% 740,786 $2.7M Add +110.2%
ORKA Oruka Therapeutics Inc. 1.00% 27,799 $2.6M New
PCVX Vaxcyte Inc. 0.99% 45,071 $2.6M Add +79.8%
RLMD Relmada Therapeutics Inc. 0.95% 361,367 $2.5M Add +79.9%
VERA Vera Therapeutics Inc. 0.93% 57,608 $2.5M New
CTNM Contineum Therapeutics Inc. Class A 0.74% 119,733 $2.0M New
BCYC Bicycle Therapeutics PLC-ADR 0.74% 462,724 $2.0M Reduce -2.9%
GLUE Monte Rosa Therapeutics Inc. 0.72% 78,391 $1.9M Reduce -58.1%
VRDN Viridian Therapeutics Inc. 0.69% 100,000 $1.8M New
MGNX Macrogenics Inc. 0.65% 374,403 $1.7M Reduce -37.6%
PRQR Proqr Therapeutics NV 0.65% 926,016 $1.7M Add +414.2%
SPRB Spruce Biosciences Inc. 0.61% 30,000 $1.6M Add +200.0%
ARDX Ardelyx Inc. 0.58% 303,025 $1.5M New
CUE Cue Biopharma Inc. 0.58% 48,369 $1.5M New
MLYS Mineralys Therapeutics Inc. 0.57% 56,347 $1.5M Add +113.9%
PRTA Prothena Corp. PLC 0.55% 149,482 $1.5M New
VYGR Voyager Therapeutics Inc. 0.55% 413,642 $1.4M Reduce -2.4%
UNCY Unicycive Therapeutics Inc. 0.54% 303,676 $1.4M Add +186.3%
PHAT Phathom Pharmaceuticals Inc. 0.53% 129,950 $1.4M Add +137.8%
SYRE Spyre Therapeutics Inc. 0.50% 15,000 $1.3M New
HELP Cybin Inc. 0.50% 200,000 $1.3M New
EQ Equillium Inc. 0.48% 400,282 $1.3M Reduce -7.7%
XERS Xeris Biopharma Holdings Inc. 0.40% 132,746 $1.1M No change
PHVS Pharvaris NV 0.38% 29,321 $1.0M No change
HRMY Harmony Biosciences Holdings 0.37% 26,864 $978K Reduce -71.1%
RNAC Cartesian Therapeutics Inc. 0.34% 87,057 $907K New
RIGL Rigel Pharmaceuticals Inc. 0.34% 22,816 $893K New
SMMT Summit Therapeutics Inc. 0.33% 60,000 $874K New
PGEN Precigen Inc. 0.29% 135,293 $771K Add +144.7%
DFTX Definium Therapeutics Inc. 0.27% 15,451 $727K New
PTHS Pelthos Therapeutics Inc. 0.26% 24,773 $700K No change
PEPG Pepgen Inc. 0.25% 373,284 $672K Add +147.3%
ELVN Enliven Therapeutics Inc. 0.19% 10,000 $508K Add +3981.6%
CNTB Connect Biopharma Holdings L 0.18% 196,985 $469K Reduce -1.9%
LRMR Larimar Therapeutics Inc. 0.17% 146,637 $447K Reduce -12.0%
CLRB Cellectar Biosciences Inc. 0.15% 138,341 $385K New
FHTX Foghorn Therapeutics Inc. 0.12% 66,908 $327K Reduce -16.3%
AYTU Aytu Biopharma Inc. 0.12% 148,546 $319K Reduce -57.9%
OCGN Ocugen Inc. 0.12% 200,000 $306K No change
URGN Urogen Pharma Ltd. 0.10% 7,137 $263K Reduce -69.2%
AMGN Amgen Inc. 0.08% 102,701 $215K New
HRTX Heron Therapeutics Inc. 0.07% 458,723 $196K New
TLPH Talphera Inc. 0.06% 153,563 $158K No change
ANNX Annexon Inc. 0.06% 27,516 $157K Reduce -79.3%
MNPR Monopar Therapeutics Inc. 0.06% 1,630 $151K No change
LAKE Lakeland Industries Inc. 0.06% 14,108 $151K New
UPB Upstream Bio Inc. 0.05% 19,093 $132K Reduce -11.6%
MGTX Meiragtx Holdings PLC 0.04% 8,368 $113K New
JATT Jatt II Acquisition Corp. 0.04% 9,021 $102K New
KLRA Kailera Therapeutics Inc. 0.03% 3,621 $80K New
MNKD Mannkind Corp. 0.03% 16,003 $68K Reduce -91.4%
ENTX Entera Bio Ltd. 0.02% 23,260 $41K No change
SPRY Ars Pharmaceuticals Inc. 0.01% 4,860 $39K New
APRE Aprea Therapeutics Inc. 0.01% 44,907 $36K New
TVRD Tvardi Therapeutics Inc. 0.01% 16,607 $32K New
NXTC Nextcure Inc. 0.00% 7,742 $12K New

Options reported separately and not counted above: VKTX calls ($47.6M), ABVX calls ($46.5M), BMY calls ($34.6M), ABVX puts ($33.6M), BMY puts ($19.0M), CORT calls ($17.9M), KYMR calls ($17.2M), NVS puts ($15.7M), QURE puts ($13.8M), VKTX puts ($13.7M), BIIB calls ($13.0M), CAPR puts ($12.9M), and 59 more.

Other holdings (1): bonds, preferreds, convertibles and warrants · $186K (not counted above)
SecurityClassShares / PrincipalValueChange
BRIDGEBIO PHARMA INC (BBIO 1.75 03/01/31) NOTE 1.750% 3/0 · principal 250,000$186KNew

Total filed on the 13F, all lines: $264.7M.

Portfolio Sells Q1 2026 → Q2 2026

BRIDGEBIO PHARMA INC (BBIO 1.75 03/01/31) Sold out 0.00% −7.67
JAZZ Jazz Pharmaceuticals PLC Sold out 0.00% −4.27
TERN Terns Pharmaceuticals Inc. Sold out 0.00% −3.96
JNJ Johnson & Johnson Reduce -59.1% 2.11% −3.32
INCY Incyte Corp. Sold out 0.00% −3.03
TGTX TG Therapeutics Inc. Sold out 0.00% −2.84
BBIO Bridgebio Pharma Inc. Sold out 0.00% −2.62
LLY Eli Lilly & Co. Sold out 0.00% −2.28
ABBV Abbvie Inc. Sold out 0.00% −2.16
GPCR Structure Therapeutics Inc. Sold out 0.00% −1.44
TENX Tenax Therapeutics Inc. Sold out 0.00% −1.19
CAPR Capricor Therapeutics Inc. Sold out 0.00% −0.99
EYPT Eyepoint Inc. Sold out 0.00% −0.95
CLYM Climb Bio Inc. Sold out 0.00% −0.81
STTK Shattuck Labs Inc. Sold out 0.00% −0.78
TARS Tarsus Pharmaceuticals Inc. Sold out 0.00% −0.75
ALKS Alkermes PLC Sold out 0.00% −0.73
VRTX Vertex Pharmaceuticals Inc. Sold out 0.00% −0.71
HRMY Harmony Biosciences Holdings Reduce -71.1% 0.37% −0.70
CRBP Corbus Pharmaceuticals Holdi Reduce -31.5% 1.07% −0.64
GLUE Monte Rosa Therapeutics Inc. Reduce -58.1% 0.72% −0.56
VKTX Viking Therapeutics Inc. Reduce -15.9% 6.51% −0.54
INO Inovio Pharmaceuticals Inc. Sold out 0.00% −0.40
DNTH Dianthus Therapeutics Inc. Sold out 0.00% −0.35
ENTA Enanta Pharmaceuticals Inc. Sold out 0.00% −0.34
REPL Replimune Group Inc. Sold out 0.00% −0.32
RARE Ultragenyx Pharmaceutical Inc. Sold out 0.00% −0.30
AYTU Aytu Biopharma Inc. Reduce -57.9% 0.12% −0.28
CELC Celcuity Inc. Sold out 0.00% −0.25
ANNX Annexon Inc. Reduce -79.3% 0.06% −0.24
QURE Uniqure NV Sold out 0.00% −0.21
MAZE Maze Therapeutics Inc. Sold out 0.00% −0.18
BCYC Bicycle Therapeutics PLC-ADR Reduce -2.9% 0.74% −0.17
CORT Corcept Therapeutics Inc. Sold out 0.00% −0.17
LPCN Lipocine Inc. Sold out 0.00% −0.17
MNKD Mannkind Corp. Reduce -91.4% 0.03% −0.16
GHRS GH Research PLC Sold out 0.00% −0.16
LRMR Larimar Therapeutics Inc. Reduce -12.0% 0.17% −0.14
VYGR Voyager Therapeutics Inc. Reduce -2.4% 0.55% −0.13
EPRX Eupraxia Pharmaceuticals Inc. Sold out 0.00% −0.12
TRVI Trevi Therapeutics Inc. Sold out 0.00% −0.11
CMPS Compass Pathways PLC Sold out 0.00% −0.07
URGN Urogen Pharma Ltd. Reduce -69.2% 0.10% −0.07
PASG Passage Bio Inc. Sold out 0.00% −0.06
MGNX Macrogenics Inc. Reduce -37.6% 0.65% −0.06
RCKT Rocket Pharmaceuticals Inc. Sold out 0.00% −0.05
CNTB Connect Biopharma Holdings L Reduce -1.9% 0.18% −0.04
FHTX Foghorn Therapeutics Inc. Reduce -16.3% 0.12% −0.03
UPB Upstream Bio Inc. Reduce -11.6% 0.05% −0.03
VTGN Vistagen Therapeutics Inc. Sold out 0.00% −0.02

Portfolio Buys Q1 2026 → Q2 2026

RVMD Revolution Medicines Inc. Add +72.2% 9.86% +6.61
ABVX Abivax SA-ADR Add +115.5% 8.16% +4.77
EWTX Edgewise Therapeutics Inc. New 4.18% +4.18
UTHR United Therapeutics Corp. Add +94.1% 10.85% +4.17
BMRN Biomarin Pharmaceutical Inc. Add +111.1% 6.77% +3.31
FDMT 4D Molecular Therapeutics Inc. New 2.87% +2.87
COGT Cogent Biosciences Inc. Add +53.0% 7.22% +2.09
RLAY Relay Therapeutics Inc. New 1.63% +1.63
NVO Novo-Nordisk A/S-Spons ADR Add +586.0% 1.82% +1.60
TSHA Taysha Gene Therapies Inc. New 1.35% +1.35
NRIX Nurix Therapeutics Inc. New 1.11% +1.11
ORKA Oruka Therapeutics Inc. New 1.00% +1.00
VERA Vera Therapeutics Inc. New 0.93% +0.93
BIOA Bioage Labs Inc. Add +143.9% 1.36% +0.92
CTNM Contineum Therapeutics Inc. Class A New 0.74% +0.74
VRDN Viridian Therapeutics Inc. New 0.69% +0.69
IMCR Immunocore Holdings PLC-ADR Add +31.9% 3.06% +0.65
ARDX Ardelyx Inc. New 0.58% +0.58
CUE Cue Biopharma Inc. New 0.58% +0.58
PRTA Prothena Corp. PLC New 0.55% +0.55
PRQR Proqr Therapeutics NV Add +414.2% 0.65% +0.53
SYRE Spyre Therapeutics Inc. New 0.50% +0.50
HELP Cybin Inc. New 0.50% +0.50
PCVX Vaxcyte Inc. Add +79.8% 0.99% +0.39
RLMD Relmada Therapeutics Inc. Add +79.9% 0.95% +0.37
RNAC Cartesian Therapeutics Inc. New 0.34% +0.34
SPRB Spruce Biosciences Inc. Add +200.0% 0.61% +0.34
RIGL Rigel Pharmaceuticals Inc. New 0.34% +0.34
SMMT Summit Therapeutics Inc. New 0.33% +0.33
PHAT Phathom Pharmaceuticals Inc. Add +137.8% 0.53% +0.28
MLYS Mineralys Therapeutics Inc. Add +113.9% 0.57% +0.28
DFTX Definium Therapeutics Inc. New 0.27% +0.27
UNCY Unicycive Therapeutics Inc. Add +186.3% 0.54% +0.25
IVA Inventiva SA - ADR Add +110.2% 1.03% +0.23
PGEN Precigen Inc. Add +144.7% 0.29% +0.20
ELVN Enliven Therapeutics Inc. Add +3981.6% 0.19% +0.19
CRVS Corvus Pharmaceuticals Inc. Add +20.4% 1.66% +0.19
KOD Kodiak Sciences Inc. Add +13.0% 3.21% +0.17
CLRB Cellectar Biosciences Inc. New 0.15% +0.15
PEPG Pepgen Inc. Add +147.3% 0.25% +0.14
AMGN Amgen Inc. New 0.08% +0.08
HRTX Heron Therapeutics Inc. New 0.07% +0.07
LAKE Lakeland Industries Inc. New 0.06% +0.06
MGTX Meiragtx Holdings PLC New 0.04% +0.04
JATT Jatt II Acquisition Corp. New 0.04% +0.04
KLRA Kailera Therapeutics Inc. New 0.03% +0.03
SPRY Ars Pharmaceuticals Inc. New 0.01% +0.01
APRE Aprea Therapeutics Inc. New 0.01% +0.01
TVRD Tvardi Therapeutics Inc. New 0.01% +0.01
NXTC Nextcure Inc. New 0.00% +0.00

Options Activity Q1 2026 → Q2 2026

VKTX Viking Therapeutics Inc. call Add +85.2% 1,220,800 $47.6M
ABVX Abivax SA-ADR call Add +249.2% 349,200 $46.5M
VRTX Vertex Pharmaceuticals Inc. call Sold out 93,100 $41.6Mbefore exit
BMY Bristol-Myers Squibb Co. call New 600,000 $34.6M
ABVX Abivax SA-ADR put Add +152.4% 252,400 $33.6M
LQDA Liquidia Corp. call Sold out 662,100 $25.0Mbefore exit
UTHR United Therapeutics Corp. call Sold out 40,200 $23.8Mbefore exit
BMY Bristol-Myers Squibb Co. put New 330,600 $19.0M
APGE Apogee Therapeutics Inc. call Sold out 222,500 $18.7Mbefore exit
CORT Corcept Therapeutics Inc. call Add +30.2% 206,300 $17.9M
KYMR Kymera Therapeutics Inc. call New 149,700 $17.2M
NVS Novartis AG-Sponsored ADR put New 100,000 $15.7M
VKTX Viking Therapeutics Inc. put New 350,500 $13.7M
BIIB Biogen Inc. call New 60,000 $13.0M
CAPR Capricor Therapeutics Inc. put Reduce -14.3% 534,400 $12.9M
SMMT Summit Therapeutics Inc. call New 860,200 $12.5M
RVMD Revolution Medicines Inc. put Sold out 125,500 $12.2Mbefore exit
MRK Merck & Co. Inc. put Sold out 100,000 $12.0Mbefore exit
LLY Eli Lilly & Co. put New 10,000 $12.0M
UTHR United Therapeutics Corp. put Sold out 20,000 $11.9Mbefore exit
QURE Uniqure NV call Reduce -5.8% 235,400 $10.8M
BNTX Biontech SE-ADR call New 100,000 $9.3M
ROIV Roivant Sciences Ltd. put Sold out 335,800 $9.3Mbefore exit
NVS Novartis AG-Sponsored ADR call New 50,000 $7.8M
REPL Replimune Group Inc. call Add +238.8% 696,300 $7.7M
KOD Kodiak Sciences Inc. call Add +98250.0% 196,700 $7.7M
MRNA Moderna Inc. put Reduce -37.3% 100,000 $7.0M
HIMS Hims & Hers Health Inc. call New 200,000 $6.9M
HIMS Hims & Hers Health Inc. put New 193,700 $6.7M
EWTX Edgewise Therapeutics Inc. call Sold out 212,500 $6.7Mbefore exit
GPCR Structure Therapeutics Inc. put Sold out 127,500 $6.1Mbefore exit
CRBP Corbus Pharmaceuticals Holdi call Add +449.7% 633,800 $5.9M
SLS Sellas Life Sciences Group I call Add +33.3% 400,000 $5.9M
KOD Kodiak Sciences Inc. put Reduce -40.5% 146,900 $5.7M
ALMS Alumis Inc. call Add +100.0% 200,000 $5.6M
RPRX Royalty Pharma PLC Class A call New 100,000 $5.6M
REPL Replimune Group Inc. put Add +9.3% 502,500 $5.6M
CRSP Crispr Therapeutics AG call Sold out 106,300 $5.1Mbefore exit
BIOA Bioage Labs Inc. call New 200,100 $4.9M
TENX Tenax Therapeutics Inc. call New 307,000 $4.5M
TGTX TG Therapeutics Inc. call New 75,700 $4.2M
GLUE Monte Rosa Therapeutics Inc. call New 170,100 $4.1M
RCUS Arcus Biosciences Inc. call New 124,000 $3.8M
UNCY Unicycive Therapeutics Inc. call New 792,600 $3.7M
AMGN Amgen Inc. call New 10,000 $3.6M
CYTK Cytokinetics Inc. call Sold out 50,000 $3.3Mbefore exit
CLDX Celldex Therapeutics Inc. put New 86,000 $3.2M
SMMT Summit Therapeutics Inc. put New 200,000 $2.9M
PCVX Vaxcyte Inc. put New 48,900 $2.8M
CYTK Cytokinetics Inc. put Reduce -85.0% 30,000 $2.6M

Showing the first 50 of 84.

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

Notes & Other Activity Q1 2026 → Q2 2026

BRIDGEBIO PHARMA INC (BBIO 1.75 03/01/31) NOTE 1.750% 3/0 · principal New 250,000 $186K

Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 77$264.6MUTHR, RVMD, ABVX, COGT, BMRN
Q1 2026 86$242.2MBRIDGEBIO PHARMA INC (BBIO 1.75 03/01/31), VKTX, UTHR, JNJ, COGT
Q4 2025 73$167.9MTERN, JNJ, VKTX, ABVX, BMRN
Q3 2025 59$143.6MREGN, SLNO, BMRN, PCVX, INDV
Q2 2025 46$160.8MSLNO, AMGN, TGTX, NBIX, LLY
Q1 2025 43$125.1MREGN, LLY, JAZZ, TGTX, ARGX
Q4 2024 54$88.7MBMY, ABBV, TEVA, BPMC, RYTM