NextcureNXTC
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 24 institutions reported holding Nextcure Inc. (NXTC) in their 13F filings, up 8 from Q3 2025. 9 opened new positions and 2 sold out. The largest holders were Affinity Asset Advisors, LLC ($3.5M), Ikarian Capital, LLC ($3.4M) and Squadron Capital Management LLC ($3.4M). 2 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Nextcure Inc.
- CUSIP
- 65343E207
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 9 | $11.5M |
| Exits | 2 | $370K |
All 13F filers, Q3 2025 → Q4 2025: 900,997 shares bought and 76,645 shares sold, net +824,352 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 24 holders
| Affinity Asset Advisors, LLC | 0.26% | Add +28.9% | 247,294 | $3.5M |
| Ikarian Capital, LLC | 0.44% | New | 238,303 | $3.4M |
| Squadron Capital Management LLC | 1.50% | — | 236,966 | $3.4M |
| Sofinnova Investments, Inc. | 0.14% | No change | 222,654 | $3.2M |
| Silverarc Capital Management, LLC | 0.36% | New | 176,057 | $2.5M |
| Exome Asset Management LLC | 1.16% | New | 165,000 | $2.3M |
| Pfizer Inc | 0.95% | No change | 157,646 | $2.2M |
| AWM Investment Company, Inc. | 0.16% | New | 117,371 | $1.7M |
| Vanguard Group Inc. | 0.00% | Add +35.2% | 91,910 | $1.3M |
| Boothbay Fund Management, LLC | 0.03% | New | 69,617 | $988K |
| Renaissance Technologies | 0.00% | Add +18.7% | 33,634 | $477K |
| BlackRock, Inc. | 0.00% | Reduce -10.6% | 27,793 | $394K |
| Acadian Asset Management LLC | 0.00% | Reduce -27.0% | 26,765 | $379K |
| Geode Capital Management, LLC | 0.00% | Add +18.6% | 23,157 | $329K |
| Cardiff Park Advisors, LLC | 0.03% | New | 21,833 | $310K |
| Millennium Management | 0.00% | New | 13,033 | $185K |
| Marshall Wace, LLP | 0.00% | New | 11,292 | $160K |
| Sio Capital Management, LLC | 0.03% | No change | 10,940 | $155K |
| Barclays PLC | 0.00% | No change | 5,626 | $80K |
| UBS Group AG | 0.00% | Reduce -43.8% | 338 | $5K |
| Bank of America Corp. | 0.00% | Add +652.2% | 173 | $2K |
| Morgan Stanley | 0.00% | New | 66 | $937 |
| JPMorgan Chase & Co. | 0.00% | No change | 61 | $866 |
| BNP Paribas Financial Markets | 0.00% | No change | 32 | $454 |
"% of holder's portfolio" is NXTC's weight in each manager's 13F, not the share of Nextcure Inc. the manager owns.