Wave Life SciencesWVE
13F holders, Q4 2025 (December 31)219holders +30
63new positions
37sold out
7famous investors
$17.01avg. 13F price*
At the end of Q4 2025, 219 institutions reported holding Wave Life Sciences Ltd. (WVE) in their 13F filings, up 30 from Q3 2025. 63 opened new positions and 37 sold out. The largest holders were GSK plc ($310.2M), Ra Capital Management, L.P. ($309.5M) and FMR LLC ($257.3M). 7 famous investors held it, including Lee Ainslie (1.7% of Maverick Capital's portfolio), Stanley Druckenmiller (0.1% of Duquesne Family Office's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Wave Life Sciences Ltd.
- CUSIP
- Y95308105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 63 | $292.4M |
| Exits | 37 | $61.8M |
All 13F filers, Q3 2025 → Q4 2025: 44,380,072 shares bought and 24,400,921 shares sold, net +19,979,151 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 219 holders
| GSK plc | 38.82% | — | 18,245,691 | $310.2M |
| Ra Capital Management, L.P. | 3.17% | Add +0.0% | 18,203,009 | $309.5M |
| FMR LLC | 0.01% | Add +195.0% | 15,135,983 | $257.3M |
| BlackRock, Inc. | 0.00% | Add +21.3% | 12,648,907 | $215.0M |
| Adage Capital Partners Gp, L.L.C. | 0.25% | Reduce -32.8% | 9,786,061 | $166.4M |
| Maverick Capital | 1.69% | Add +10.6% | 9,280,237 | $157.8M |
| T. Rowe Price Associates Inc. | 0.01% | Add +83.2% | 7,407,372 | $125.9M |
| Darwin Global Management, Ltd. | 2.53% | New | 7,298,421 | $125.2M |
| Driehaus Capital Management LLC | 0.76% | Add +4.5% | 6,581,067 | $111.9M |
| M28 Capital Management LP | 70.00% | No change | 5,664,548 | $96.3M |
| Federated Hermes, Inc. | 0.13% | Add +26.5% | 4,744,520 | $80.7M |
| Primecap Management Co. | 0.05% | Add +115.7% | 4,095,282 | $69.6M |
| 683 Capital Management, LLC | 5.98% | Reduce -3.3% | 4,015,000 | $68.3M |
| Vanguard Group Inc. | 0.00% | Add +13.8% | 3,573,746 | $60.8M |
| Geode Capital Management, LLC | 0.00% | Add +8.6% | 3,170,110 | $53.9M |
| State Street Corp. | 0.00% | Add +5.3% | 2,996,084 | $50.9M |
| Goldman Sachs Group Inc. | 0.01% | Add +34.3% | 2,854,082 | $48.5M |
| Affinity Asset Advisors, LLC | 3.40% | Add +28.6% | 2,700,000 | $45.9M |
| Emerald Advisers, LLC | 1.29% | Reduce -18.1% | 2,455,089 | $41.7M |
| Siren, L.L.C. | 1.24% | Reduce -33.7% | 2,450,000 | $41.6M |
| Kynam Capital Management, LP | 2.40% | Reduce -52.4% | 2,169,105 | $36.9M |
| Loomis Sayles & Co. L P | 0.04% | Reduce -29.8% | 2,040,223 | $34.7M |
| Pfizer Inc | 13.48% | No change | 1,875,000 | $31.9M |
| First Light Asset Management, LLC | 2.41% | New | 1,853,851 | $31.5M |
| Bellevue Group AG | 0.48% | Reduce -63.6% | 1,490,518 | $25.3M |
| Emerald Mutual Fund Advisers Trust | 1.17% | Reduce -19.9% | 1,414,665 | $24.0M |
| RTW Investments, LP | 0.23% | Add +50.0% | 1,350,000 | $22.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +19.3% | 1,191,361 | $20.3M |
| Northern Trust Corp. | 0.00% | Add +2.1% | 1,033,068 | $17.6M |
| Schroder Investment Management Group | 0.01% | Add +81.1% | 1,005,984 | $17.3M |
| JPMorgan Chase & Co. | 0.00% | Add +3.8% | 892,886 | $15.2M |
| Squarepoint Ops LLC | 0.03% | Add +223.0% | 883,586 | $15.0M |
| Pictet Asset Management Holding SA | 0.01% | Add +5024.6% | 805,901 | $13.8M |
| Citadel Advisors | 0.01% | New | 789,964 | $13.4M |
| Two Sigma Investments, LP | 0.02% | Add +33.1% | 749,448 | $12.7M |
| Voloridge Investment Management, LLC | 0.04% | New | 722,237 | $12.3M |
| Tang Capital Management LLC | 0.50% | New | 600,000 | $10.2M |
| Millennium Management | 0.01% | Add +49.6% | 584,633 | $9.9M |
| Eventide Asset Management, LLC | 0.13% | New | 500,000 | $8.5M |
| Kennedy Capital Management LLC | 0.18% | Reduce -8.9% | 492,437 | $8.4M |
| Elmind Capital, LP | 2.25% | — | 447,846 | $7.6M |
| Exome Asset Management LLC | 3.54% | New | 421,488 | $7.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +11.6% | 411,494 | $7.0M |
| Morgan Stanley | 0.00% | Reduce -19.2% | 409,663 | $7.0M |
| Sphera Funds Management LTD. | 1.45% | Add +716.3% | 408,166 | $6.9M |
| Ameriprise Financial Inc. | 0.00% | Add +269.4% | 398,416 | $6.8M |
| F/m Investments LLC | 0.26% | Add +24.5% | 395,894 | $6.7M |
| Trexquant Investment LP | 0.06% | New | 391,111 | $6.6M |
| Susquehanna International Group, LLP | 0.01% | Add +93.1% | 378,987 | $6.4M |
| Walleye Capital LLC | 0.04% | Reduce -48.1% | 378,823 | $6.4M |
| Wellington Management Group LLP | 0.00% | Reduce -15.0% | 365,235 | $6.2M |
| Boone Capital Management LLC | 1.88% | New | 352,144 | $6.0M |
| Woodline Partners LP | 0.02% | New | 350,531 | $6.0M |
| Baker Bros. Advisors LP | 0.03% | No change | 344,063 | $5.8M |
| Jacobs Levy Equity Management, Inc. | 0.02% | New | 338,546 | $5.8M |
| Nuveen, LLC | 0.00% | Add +33.4% | 332,735 | $5.7M |
| Jain Global LLC | 0.06% | New | 328,145 | $5.6M |
| Bank of New York Mellon Corp | 0.00% | Add +7.9% | 321,445 | $5.5M |
| Jump Financial, LLC | 0.07% | New | 313,509 | $5.3M |
| Newtyn Management, LLC | 0.54% | No change | 300,000 | $5.1M |
| HRT Financial LP | 0.02% | New | 299,718 | $5.1M |
| Barclays PLC | 0.00% | Add +1.4% | 276,781 | $4.7M |
| Moody Aldrich Partners LLC | 0.87% | Reduce -21.7% | 274,425 | $4.7M |
| UBS Group AG | 0.00% | Reduce -61.9% | 268,723 | $4.6M |
| D. E. Shaw & Co. | 0.00% | New | 266,132 | $4.5M |
| TD Asset Management Inc | 0.00% | Add +77.1% | 252,160 | $4.3M |
| Informed Momentum Co LLC | 0.47% | New | 248,815 | $4.2M |
| Renaissance Technologies | 0.01% | New | 236,420 | $4.0M |
| Boothbay Fund Management, LLC | 0.11% | Add +93.8% | 234,799 | $4.0M |
| Platinum Investment Management Ltd. | 0.91% | Reduce -13.9% | 230,687 | $3.9M |
| Susquehanna Portfolio Strategies, LLC | 0.06% | Reduce -24.5% | 230,512 | $3.9M |
| Swiss National Bank | 0.00% | Add +4.1% | 219,700 | $3.7M |
| Nomura Asset Management International Inc. | 0.01% | — | 203,744 | $3.5M |
| AQR Capital Management | 0.00% | Add +1794.9% | 202,721 | $3.4M |
| Wells Fargo & Company | 0.00% | Add +172.2% | 200,890 | $3.4M |
| Privium Fund Management B.V. | 0.60% | Add +13.5% | 193,010 | $3.3M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +45.8% | 182,728 | $3.1M |
| Bank of America Corp. | 0.00% | Reduce -72.5% | 182,855 | $3.1M |
| Invesco Ltd. | 0.00% | Add +27.5% | 179,932 | $3.1M |
| Squadron Capital Management LLC | 1.33% | — | 175,000 | $3.0M |
| Duquesne Family Office | 0.07% | New | 173,000 | $2.9M |
| Principal Financial Group Inc. | 0.00% | New | 170,170 | $2.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 164,985 | $2.8M |
| Sofinnova Investments, Inc. | 0.12% | Reduce -7.5% | 158,182 | $2.7M |
| Burkehill Global Management, LP | 0.18% | New | 150,000 | $2.5M |
| Rhumbline Advisers | 0.00% | Reduce -10.8% | 141,895 | $2.4M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +0.2% | 134,558 | $2.3M |
| Algert Global LLC | 0.03% | New | 122,470 | $2.1M |
| Voya Investment Management LLC | 0.00% | Reduce -56.3% | 112,875 | $1.9M |
| Alliancebernstein L.P. | 0.00% | Add +20.7% | 112,030 | $1.9M |
| Raymond James Financial Inc. | 0.00% | Add +608.7% | 111,170 | $1.9M |
| Jane Street Group, LLC | 0.00% | Reduce -82.1% | 110,924 | $1.9M |
| California State Teachers Retirement System | 0.00% | Add +9.3% | 107,680 | $1.8M |
| James J. Burns & Company, LLC | 0.25% | No change | 105,802 | $1.8M |
| Itau Unibanco Holding S.A. | 0.04% | New | 102,000 | $1.7M |
| Seven Grand Managers, LLC | 0.13% | New | 100,000 | $1.7M |
| LMR Partners LLP | 0.02% | New | 100,000 | $1.7M |
| Deutsche Bank AG | 0.00% | Add +1.5% | 95,706 | $1.6M |
| Dark Forest Capital Management LP | 0.07% | Reduce -63.8% | 95,068 | $1.6M |
| Legal & General Group Plc | 0.00% | Reduce -7.8% | 93,985 | $1.6M |
"% of holder's portfolio" is WVE's weight in each manager's 13F, not the share of Wave Life Sciences Ltd. the manager owns.