72 Investment Holdings, LLC

In its 13F for Q3 2025 (holdings as of September 30, 2025, filed November 14, 2025), 72 Investment Holdings, LLC reported 5 stock positions worth $67.9 million. Its top holding was Lenz Therapeutics (LENZ) at 69.8% of the portfolio, followed by Korro Bio (KRRO, 19.5%) and Praxis Precision Medicines I (PRAX, 5.1%). Compared with Q2 2025, it sold out of 1. The biggest sale was an exit from Turnstone Biologics (TSBX).

Most Recent 13F
Q2 2026
Location
STAMFORD, CT
CIK
0001832749
Portfolio Value
$67.9M (Q3 2025)
SEC Filing
0000902664-25-005031 ↗ filed Nov 14, 2025

Holdings Value

0$20.0M$40.0M$60.0M$80.0M Q1 2024: $67.1M Q1 2024 Q2 2024: $39.8M Q2 2024 Q3 2024: $46.5M Q3 2024 Q4 2024: $49.1M Q4 2024 Q1 2025: $35.6M Q1 2025 Q2 2025: $38.3M Q2 2025 Q3 2025: $67.9M $67.9M Q3 2025 Q4 2025: $50.6M Q4 2025 Q1 2026: $49.6M Q1 2026 Q2 2026: $50.0M Q2 2026

Holdings 5 stocks · $67.9M
LENZ Lenz Therapeutics Inc. 69.77% 1,017,751 $47.4M No change
KRRO Korro Bio Inc. 19.51% 276,831 $13.3M No change
PRAX Praxis Precision Medicines I 5.14% 65,933 $3.5M No change
ANRO Alto Neuroscience Inc. 3.95% 667,778 $2.7M No change
CRBU Caribou Biosciences Inc. 1.63% 474,067 $1.1M No change

Portfolio Sells Q2 2025 → Q3 2025
TSBX Turnstone Biologics Corp. Sold out 0.00% −0.52

Portfolio Buys Q2 2025 → Q3 2025
None this quarter.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 5$50.0MPRAX, ANRO, LENZ, KRRO, CRBU
Q1 2026 5$49.6MPRAX, ANRO, LENZ, KRRO, CRBU
Q4 2025 5$50.6MPRAX, LENZ, ANRO, KRRO, CRBU
Q3 2025 5$67.9MLENZ, KRRO, PRAX, ANRO, CRBU
Q2 2025 6$38.3MLENZ, KRRO, PRAX, ANRO, CRBU
Q1 2025 6$35.6MLENZ, KRRO, PRAX, ANRO, CRBU
Q4 2024 7$49.1MLENZ, KRRO, PRAX, ANRO, CRBU
Q3 2024 7$46.5MLENZ, KRRO, ANRO, PRAX, CRBU
Q2 2024 7$39.8MLENZ, KRRO, ANRO, PRAX, TSBX
Q1 2024 7$67.1MKRRO, LENZ, ANRO, PRAX, CRBU