Alta Partners Management Company, L.P.

In its 13F for Q4 2025 (holdings as of December 31, 2025, filed January 13, 2026), Alta Partners Management Company, L.P. reported 2 stock positions worth $103.6 million. Its top holding was Tyra Biosciences (TYRA) at 97.0% of the portfolio, followed by Vir Biotechnology (VIR, 3.0%). Compared with Q3 2025, it reduced 1. The biggest sale was Tyra Biosciences (TYRA, shares −6%).

Most Recent 13F
Q2 2026
Location
JACKSON, WY
CIK
0002054419
Portfolio Value
$103.6M (Q4 2025)
SEC Filing
0002054419-26-000003 ↗ filed Jan 13, 2026

Holdings Value

0$50.0M$100.0M$150.0M$200.0M Q4 2024: $63.4M Q4 2024 Q1 2025: $41.8M Q1 2025 Q2 2025: $41.6M Q2 2025 Q3 2025: $60.0M Q3 2025 Q4 2025: $103.6M $103.6M Q4 2025 Q1 2026: $151.0M Q1 2026 Q2 2026: $127.3M Q2 2026

Holdings 2 stocks · $103.6M
TYRA Tyra Biosciences Inc. 97.03% 3,823,425 $100.5M Reduce -6.3%
VIR Vir Biotechnology Inc. 2.97% 509,917 $3.1M No change

Portfolio Sells Q3 2025 → Q4 2025
TYRA Tyra Biosciences Inc. Reduce -6.3% 97.03% +1.89

Portfolio Buys Q3 2025 → Q4 2025
None this quarter.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 2$127.3MTYRA, VIR
Q1 2026 2$151.0MTYRA, VIR
Q4 2025 2$103.6MTYRA, VIR
Q3 2025 2$60.0MTYRA, VIR
Q2 2025 2$41.6MTYRA, VIR
Q1 2025 3$41.8MTYRA, VIR, ALLK
Q4 2024 3$63.4MTYRA, VIR, ALLK