Tyra BiosciencesTYRA
13F holders, Q2 2026 (June 30)168holders +4
30new positions
26sold out
5famous investors
$31.95avg. 13F price*
At the end of Q2 2026, 168 institutions reported holding Tyra Biosciences Inc. (TYRA) in their 13F filings, up 4 from Q1 2026. 30 opened new positions and 26 sold out. The largest holders were Ra Capital Management, L.P. ($389.6M), FMR LLC ($284.9M) and Jupiter Topco LLC ($139.2M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Fisher (0.0% of Fisher Asset Management's portfolio).
- Company
- Tyra Biosciences Inc.
- CUSIP
- 90240B106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 30 | $98.6M |
| Exits | 26 | $208.8M |
All 13F filers, Q1 2026 → Q2 2026: 12,995,128 shares bought and 10,054,883 shares sold, net +2,940,245 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 168 holders
| Ra Capital Management, L.P. | 3.39% | No change | 12,198,625 | $389.6M |
| FMR LLC | 0.01% | Add +15.1% | 8,920,513 | $284.9M |
| Jupiter Topco LLC | 0.06% | — | 4,352,448 | $139.2M |
| Alta Partners Management Company, L.P. | 95.92% | No change | 3,823,425 | $122.1M |
| Nextech Invest Ltd. | 5.39% | Reduce -12.4% | 3,553,585 | $113.5M |
| TCG Crossover Management, LLC | 2.49% | No change | 3,248,980 | $103.8M |
| BlackRock, Inc. | 0.00% | Add +36.7% | 3,031,972 | $96.8M |
| T. Rowe Price Associates Inc. | 0.01% | Add +182.2% | 2,782,567 | $88.9M |
| State Street Corp. | 0.00% | Add +76.0% | 2,140,368 | $68.4M |
| Commodore Capital LP | 3.57% | Reduce -24.2% | 1,875,000 | $59.9M |
| Paradigm Biocapital Advisors LP | 1.09% | Reduce -11.0% | 1,828,607 | $58.4M |
| Vanguard Capital Management LLC | 0.00% | Add +34.0% | 1,508,447 | $48.2M |
| BVF Inc. | 1.21% | Reduce -25.3% | 1,476,196 | $47.1M |
| 5AM Venture Management, LLC | 11.42% | No change | 1,029,298 | $32.9M |
| Deerfield Management Company, L.P. | 0.40% | Add +85.3% | 1,017,000 | $32.5M |
| Hood River Capital Management LLC | 0.24% | New | 1,016,775 | $32.5M |
| Geode Capital Management, LLC | 0.00% | Add +47.4% | 970,734 | $31.0M |
| Caligan Partners LP | 1.24% | Reduce -36.8% | 806,986 | $25.8M |
| Canaan Partners XI LLC | 18.82% | No change | 750,000 | $24.0M |
| Siren, L.L.C. | 0.47% | New | 725,000 | $23.2M |
| Sio Capital Management, LLC | 3.81% | Add +14.8% | 695,315 | $22.2M |
| Stempoint Capital LP | 3.50% | Add +227.6% | 632,754 | $20.2M |
| Marshall Wace, LLP | 0.02% | Add +194.9% | 583,133 | $18.6M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -15.8% | 463,477 | $14.8M |
| Jennison Associates LLC | 0.01% | Reduce -28.7% | 450,964 | $14.4M |
| Two Sigma Investments, LP | 0.01% | Add +342.6% | 449,808 | $14.4M |
| Vanguard Portfolio Management LLC | 0.00% | Add +63.0% | 403,019 | $12.9M |
| Defilade Capital Management, L.P. | 1.61% | New | 376,870 | $12.0M |
| Bank of America Corp. | 0.00% | Add +66.6% | 349,732 | $11.2M |
| Walleye Capital LLC | 0.06% | Add +1758.9% | 347,898 | $11.1M |
| Woodline Partners LP | 0.03% | Add +6.3% | 320,040 | $10.2M |
| Northern Trust Corp. | 0.00% | Add +41.9% | 310,084 | $9.9M |
| Morgan Stanley | 0.00% | Add +149.3% | 300,322 | $9.6M |
| Citadel Advisors | 0.01% | Add +1707.7% | 278,307 | $8.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +34.5% | 267,699 | $8.6M |
| Qube Research & Technologies Ltd | 0.01% | New | 266,934 | $8.5M |
| BNP Paribas Financial Markets | 0.00% | Add +26.4% | 240,227 | $7.7M |
| Algert Global LLC | 0.09% | Add +27.2% | 239,120 | $7.6M |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +42.5% | 224,805 | $7.2M |
| Dimensional Fund Advisors LP | 0.00% | Add +136.4% | 217,078 | $6.9M |
| Affinity Asset Advisors, LLC | 0.32% | Reduce -22.3% | 200,012 | $6.4M |
| Franklin Resources Inc. | 0.00% | Add +1383.0% | 192,340 | $6.1M |
| HighVista Strategies LLC | 1.35% | Add +40.7% | 184,774 | $5.9M |
| Raymond James Financial Inc. | 0.00% | Reduce -26.8% | 180,881 | $5.8M |
| JPMorgan Chase & Co. | 0.00% | Add +166.9% | 178,263 | $5.7M |
| Millennium Management | 0.00% | Reduce -19.8% | 177,672 | $5.7M |
| Boothbay Fund Management, LLC | 0.11% | Reduce -36.5% | 173,559 | $5.5M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | New | 162,000 | $5.2M |
| Jump Financial, LLC | 0.05% | Add +279.5% | 157,000 | $5.0M |
| Victory Capital Management Inc. | 0.00% | Add +901.9% | 152,585 | $4.9M |
| Ensign Peak Advisors, Inc | 0.01% | Add +97.8% | 146,537 | $4.7M |
| Trexquant Investment LP | 0.03% | Reduce -9.9% | 132,740 | $4.2M |
| UBS Group AG | 0.00% | Add +111.1% | 129,945 | $4.2M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Reduce -4.2% | 123,420 | $3.9M |
| Lord, Abbett & Co. LLC | 0.01% | New | 121,833 | $3.9M |
| Bank of New York Mellon Corp | 0.00% | Add +43.6% | 103,720 | $3.3M |
| Russell Investments Group, Ltd. | 0.00% | Add +45.8% | 102,703 | $3.3M |
| Orbimed Advisors LLC | 0.06% | New | 102,000 | $3.3M |
| Jacobs Levy Equity Management, Inc. | 0.01% | Reduce -45.0% | 89,205 | $2.8M |
| Oppenheimer & Co. Inc. | 0.03% | Reduce -0.5% | 83,783 | $2.7M |
| XTX Topco Ltd | 0.03% | Reduce -3.1% | 81,320 | $2.6M |
| Nuveen, LLC | 0.00% | Add +55.0% | 78,829 | $2.5M |
| Kalehua Capital Management LLC | 1.37% | No change | 74,465 | $2.4M |
| Sei Investments Co. | 0.00% | New | 66,607 | $2.1M |
| Squarepoint Ops LLC | 0.00% | Add +211.3% | 63,805 | $2.0M |
| Citigroup Inc. | 0.00% | Add +939.5% | 62,279 | $2.0M |
| Fisher Asset Management | 0.00% | Add +109.1% | 60,230 | $1.9M |
| Alps Advisors Inc. | 0.01% | Add +37.2% | 60,159 | $1.9M |
| Wellington Management Group LLP | 0.00% | Reduce -22.8% | 59,601 | $1.9M |
| Alliancebernstein L.P. | 0.00% | Add +51.4% | 48,420 | $1.9M |
| Rhumbline Advisers | 0.00% | Add +31.2% | 52,039 | $1.7M |
| TD Asset Management Inc | 0.00% | No change | 50,000 | $1.6M |
| Arkadios Wealth Advisors | 0.02% | Add +3.7% | 49,336 | $1.6M |
| State of Wisconsin Investment Board | 0.00% | Add +40.4% | 46,697 | $1.5M |
| Susquehanna Portfolio Strategies, LLC | 0.02% | Reduce -4.6% | 44,878 | $1.4M |
| Swiss National Bank | 0.00% | Add +69.3% | 44,700 | $1.4M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +10.2% | 44,327 | $1.4M |
| ExodusPoint Capital Management, LP | 0.01% | Add +191.7% | 41,026 | $1.3M |
| Rafferty Asset Management, LLC | 0.00% | Add +11.0% | 38,702 | $1.2M |
| Deutsche Bank AG | 0.00% | Add +80.2% | 36,935 | $1.2M |
| Verdad Advisers, LP | 1.10% | New | 36,003 | $1.1M |
| Wells Fargo & Company | 0.00% | Add +187.5% | 33,561 | $1.1M |
| Sofinnova Investments, Inc. | 0.06% | Reduce -84.2% | 32,267 | $1.0M |
| Engineers Gate Manager LP | 0.01% | New | 31,958 | $1.0M |
| AQR Capital Management | 0.00% | Add +1.5% | 29,853 | $954K |
| Tema ETFs LLC | 0.03% | New | 29,519 | $943K |
| Tidal Investments LLC | 0.00% | New | 29,519 | $943K |
| SG Americas Securities, LLC | 0.00% | Add +308.1% | 29,444 | $940K |
| PDT Partners, LLC | 0.04% | Reduce -39.3% | 25,684 | $820K |
| Invesco Ltd. | 0.00% | Reduce -77.2% | 24,893 | $795K |
| California State Teachers Retirement System | 0.00% | Add +1650.6% | 24,544 | $784K |
| STRS Ohio | 0.00% | Add +22.1% | 22,100 | $706K |
| Creative Planning | 0.00% | Reduce -9.0% | 21,803 | $696K |
| MetLife Investment Management, LLC | 0.00% | Add +55.2% | 21,723 | $694K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +46.1% | 21,364 | $683K |
| LMR Partners LLP | 0.01% | New | 21,151 | $676K |
| Auour Investments LLC | 0.19% | No change | 21,020 | $671K |
| Voya Investment Management LLC | 0.00% | Reduce -47.1% | 20,282 | $648K |
| Barclays PLC | 0.00% | Reduce -97.6% | 20,275 | $648K |
| D. E. Shaw & Co. | 0.00% | New | 20,189 | $645K |
"% of holder's portfolio" is TYRA's weight in each manager's 13F, not the share of Tyra Biosciences Inc. the manager owns.