Biondo Investment Advisors, LLC
In its 13F for Q4 2025 (holdings as of December 31, 2025, filed February 13, 2026), Biondo Investment Advisors, LLC reported 86 stock positions worth $827.1 million. Its top holding was Intuitive Surgical (ISRG) at 8.2% of the portfolio, followed by Apple (AAPL, 7.1%) and Nvidia (NVDA, 6.8%). Compared with Q3 2025, it opened 2 new positions, sold out of 4, added to 43 and reduced 36. The biggest buy was Krystal Biotech (KRYS, shares +31%) and the biggest sale Nvidia (NVDA, shares −11%).
- Most Recent 13F
- Q2 2026
- Location
- MILFORD, PA
- CIK
- 0001455176
- Portfolio Value
- $827.1M (Q4 2025)
- SEC Filing
- 0001455176-26-000002 ↗ filed Feb 13, 2026
Holdings Value
Holdings 86 stocks · $827.1M
| ISRG Intuitive Surgical Inc. | 8.18% | 119,391 | $67.6M | Reduce -2.3% |
| AAPL Apple Inc. | 7.06% | 214,696 | $58.4M | Reduce -3.3% |
| NVDA Nvidia Corp. | 6.83% | 303,064 | $56.5M | Reduce -11.3% |
| GOOGL Alphabet Inc. Class A | 6.22% | 164,248 | $51.4M | Reduce -6.3% |
| MA Mastercard Inc. Class A | 4.84% | 70,168 | $40.1M | Reduce -2.1% |
| IDXX Idexx Laboratories Inc. | 4.23% | 51,735 | $35.0M | Reduce -1.0% |
| AMZN Amazon.com Inc. | 3.36% | 120,382 | $27.8M | Reduce -1.8% |
| JPM JPMorgan Chase & Co. | 3.11% | 79,947 | $25.8M | Reduce -2.7% |
| MSFT Microsoft Corp. | 2.61% | 44,624 | $21.6M | Reduce -2.9% |
| LLY Eli Lilly & Co. | 2.38% | 18,320 | $19.7M | Reduce -0.7% |
| ABBV Abbvie Inc. | 2.11% | 76,248 | $17.4M | Reduce -3.0% |
| IBM Intl Business Machines Corp. filed as INTERNATIONAL BUSINESS MACHS | 2.05% | 57,141 | $16.9M | Reduce -1.4% |
| XOM Exxon Mobil Corp. | 2.03% | 139,726 | $16.8M | Reduce -1.6% |
| KRYS Krystal Biotech Inc. | 2.03% | 68,130 | $16.8M | Add +31.3% |
| LOW Lowe's Cos Inc. | 1.79% | 61,464 | $14.8M | Reduce -0.4% |
| FICO Fair Isaac Corp. | 1.76% | 8,621 | $14.6M | Add +28.1% |
| COST Costco Wholesale Corp. | 1.63% | 15,637 | $13.5M | Reduce -0.1% |
| ASML ASML Holding NV-NY Reg SHS | 1.61% | 12,451 | $13.3M | Reduce -3.0% |
| JNJ Johnson & Johnson | 1.60% | 64,026 | $13.3M | Reduce -0.0% |
| MCD McDonald's Corp. | 1.58% | 42,684 | $13.0M | Reduce -0.2% |
| SPG Simon Property Group Inc. | 1.58% | 70,430 | $13.0M | Reduce -0.5% |
| ADBE Adobe Inc. | 1.57% | 36,990 | $12.9M | Reduce -2.3% |
| SO The Southern Co. | 1.45% | 137,799 | $12.0M | Reduce -0.7% |
| AMGN Amgen Inc. | 1.45% | 36,576 | $12.0M | Add +0.2% |
| PG The Procter & Gamble Co. | 1.39% | 80,458 | $11.5M | Add +0.1% |
| LMT Lockheed Martin Corp. | 1.39% | 23,723 | $11.5M | Add +0.1% |
| VRTX Vertex Pharmaceuticals Inc. | 1.38% | 25,140 | $11.4M | Add +0.3% |
| CVX Chevron Corp. | 1.37% | 74,469 | $11.3M | Add +0.4% |
| DUK Duke Energy Corp. | 1.33% | 93,591 | $11.0M | Reduce -0.1% |
| ADP Automatic Data Processing | 1.30% | 41,690 | $10.7M | Add +0.3% |
| ITW Illinois Tool Works | 1.28% | 42,917 | $10.6M | Add +0.4% |
| NOW ServiceNow Inc. | 1.24% | 67,123 | $10.3M | Reduce -0.1% |
| XYZ Block Inc. | 1.10% | 139,733 | $9.1M | Reduce -6.5% |
| CEG Constellation Energy | 1.10% | 25,741 | $9.1M | Add +2.1% |
| REGN Regeneron Pharmaceuticals | 1.00% | 10,673 | $8.2M | Add +29.1% |
| TMDX Transmedics Group Inc. | 0.84% | 57,215 | $7.0M | Reduce -2.0% |
| GIS General Mills Inc. | 0.81% | 143,476 | $6.7M | Reduce -2.5% |
| UNH Unitedhealth Group Inc. | 0.77% | 19,338 | $6.4M | Reduce -12.3% |
| TEAM Atlassian Corp. Class A | 0.67% | 33,976 | $5.5M | Reduce -0.7% |
| SBUX Starbucks Corp. | 0.64% | 62,973 | $5.3M | Reduce -0.8% |
| UPS United Parcel Service Class B | 0.60% | 50,368 | $5.0M | Add +3.8% |
| NVO Novo-Nordisk A/S-Spons ADR | 0.57% | 93,371 | $4.8M | Reduce -5.2% |
| FANG Diamondback Energy Inc. | 0.53% | 29,038 | $4.4M | Reduce -1.5% |
| SHOP Shopify Inc. Class A | 0.51% | 26,194 | $4.2M | Reduce -0.3% |
| IWF iShares Russell 1000 Growth | 0.41% | 7,173 | $3.4M | Add +0.7% |
| MTUM iShares MSCI USA Momentum Fa | 0.39% | 12,921 | $3.2M | Add +1.8% |
| IWP iShares Russell Mid-Cap Grow | 0.36% | 21,785 | $3.0M | Add +3.2% |
| DWAS Invesco Dorsey Wright Smallc | 0.32% | 27,608 | $2.7M | Add +3.0% |
| COHR Coherent Corp. | 0.32% | 14,400 | $2.7M | Add +10.8% |
| TDIV FT Nasdaq Tech DVD Index FD | 0.29% | 24,367 | $2.4M | Add +0.7% |
| RSP Invesco S&P 500 Equal Weight | 0.28% | 12,054 | $2.3M | Add +3.7% |
| FDVV Fidelity High Dividend ETF | 0.27% | 39,777 | $2.3M | Add +2.7% |
| IGE iShares North American Natur | 0.26% | 43,081 | $2.2M | Add +3.1% |
| REGL Prshrs S&P Mid 400 DVD Arist | 0.26% | 25,160 | $2.1M | Add +4.4% |
| IYE iShares U.S. Energy ETF | 0.26% | 44,513 | $2.1M | Add +4.5% |
| FQAL Fidelity Quality Factor ETF | 0.23% | 25,373 | $1.9M | Add +3.1% |
| DGRO iShares Core Dividend Growth | 0.21% | 24,748 | $1.7M | Add +4.0% |
| IEF iShares 7-10 Year Treasury B | 0.20% | 17,202 | $1.7M | Add +3.3% |
| SLQD iShares 0-5 YR Inv GRD Corp. | 0.20% | 32,460 | $1.6M | Add +3.8% |
| AGGM iShares 1-10 Year U.S. Aggre | 0.20% | 15,566 | $1.6M | Add +3.2% |
| TIP iShares Tips Bond ETF | 0.20% | 14,815 | $1.6M | Add +3.0% |
| DON Wisdomtree US Midcap Dividen | 0.19% | 30,598 | $1.6M | Add +5.6% |
| AGG iShares Core U.S. Aggregate | 0.19% | 15,485 | $1.5M | New |
| AIVL Wisdomtree US AI Enhanced Va | 0.19% | 13,418 | $1.5M | Add +5.8% |
| ILMN Illumina Inc. | 0.18% | 11,531 | $1.5M | Add +3.1% |
| HDV iShares Core High Dividend E | 0.18% | 12,364 | $1.5M | Add +5.7% |
| IYF iShares US Financials ETF | 0.13% | 8,363 | $1.1M | Add +2.0% |
| IYW iShares Ustechnology ETF | 0.13% | 5,278 | $1.1M | Add +1.6% |
| IUSG iShares Core S&P U.S. Growth | 0.13% | 6,178 | $1.0M | Add +0.5% |
| IYJ iShares U.S. Industrials ETF | 0.12% | 6,940 | $1.0M | Add +2.2% |
| XLY SS Consumer Disc Select Sect | 0.12% | 8,428 | $1.0M | Add +1.9% |
| XLB SS Materials Select Sector | 0.12% | 21,065 | $955K | Add +2.3% |
| GOOG Alphabet Inc. Class C | 0.10% | 2,748 | $862K | Add +1.4% |
| V Visa Inc. Class A | 0.10% | 2,359 | $827K | No change |
| PRCT Procept Biorobotics Corp. | 0.08% | 19,925 | $627K | Reduce -83.7% |
| CTOS Custom Truck One Source Inc. | 0.07% | 105,000 | $605K | Reduce -0.9% |
| TSLA Tesla Inc. | 0.07% | 1,324 | $595K | Add +13.7% |
| NFLX Netflix Inc. | 0.06% | 5,190 | $487K | Add +0.4% |
| GRAL Grail Inc. | 0.06% | 5,578 | $477K | Reduce -11.3% |
| CCJ Cameco Corp. | 0.06% | 5,000 | $457K | No change |
| IHI iShares U.S. Medical Devices | 0.05% | 6,328 | $393K | Add +2.5% |
| QQQ Invesco QQQ Trust Series 1 | 0.04% | 582 | $358K | No change |
| SPY SS SPDR S&P 500 ETF Trust-US | 0.03% | 423 | $288K | No change |
| EVLV Evolv Technologies Holdings | 0.03% | 37,500 | $269K | Reduce -11.8% |
| PNRG Primeenergy Resources Corp. | 0.03% | 1,400 | $239K | No change |
| ASND Ascendis Pharma A/S | 0.03% | 1,000 | $213K | New |
Portfolio Sells Q3 2025 → Q4 2025
| NVDA Nvidia Corp. | Reduce -11.3% | 6.83% | −1.15 |
| PRCT Procept Biorobotics Corp. | Reduce -83.7% | 0.08% | −0.47 |
| MSFT Microsoft Corp. | Reduce -2.9% | 2.61% | −0.37 |
| ZTS Zoetis Inc. | Sold out | 0.00% | −0.34 |
| NOW ServiceNow Inc. | Reduce -0.1% | 1.24% | −0.31 |
| MA Mastercard Inc. Class A | Reduce -2.1% | 4.84% | −0.26 |
| XYZ Block Inc. | Reduce -6.5% | 1.10% | −0.25 |
| TLT iShares 20+ Year Treasury BD | Sold out | 0.00% | −0.20 |
| SO The Southern Co. | Reduce -0.7% | 1.45% | −0.19 |
| COST Costco Wholesale Corp. | Reduce -0.1% | 1.63% | −0.18 |
| UNH Unitedhealth Group Inc. | Reduce -12.3% | 0.77% | −0.18 |
| ABBV Abbvie Inc. | Reduce -3.0% | 2.11% | −0.17 |
| LOW Lowe's Cos Inc. | Reduce -0.4% | 1.79% | −0.15 |
| JPM JPMorgan Chase & Co. | Reduce -2.7% | 3.11% | −0.13 |
| DUK Duke Energy Corp. | Reduce -0.1% | 1.33% | −0.13 |
| GIS General Mills Inc. | Reduce -2.5% | 0.81% | −0.12 |
| NVO Novo-Nordisk A/S-Spons ADR | Reduce -5.2% | 0.57% | −0.11 |
| ADBE Adobe Inc. | Reduce -2.3% | 1.57% | −0.11 |
| SPG Simon Property Group Inc. | Reduce -0.5% | 1.58% | −0.09 |
| MCD McDonald's Corp. | Reduce -0.2% | 1.58% | −0.05 |
| SBUX Starbucks Corp. | Reduce -0.8% | 0.64% | −0.03 |
| PCT Purecycle Technologies Inc. | Sold out | 0.00% | −0.03 |
| VRSK Verisk Analytics Inc. | Sold out | 0.00% | −0.03 |
| AAPL Apple Inc. | Reduce -3.3% | 7.06% | −0.02 |
| TEAM Atlassian Corp. Class A | Reduce -0.7% | 0.67% | −0.02 |
| CTOS Custom Truck One Source Inc. | Reduce -0.9% | 0.07% | −0.01 |
| AMZN Amazon.com Inc. | Reduce -1.8% | 3.36% | −0.01 |
| EVLV Evolv Technologies Holdings | Reduce -11.8% | 0.03% | −0.01 |
| IBM Intl Business Machines Corp. | Reduce -1.4% | 2.05% | −0.00 |
| FANG Diamondback Energy Inc. | Reduce -1.5% | 0.53% | −0.00 |
| GRAL Grail Inc. | Reduce -11.3% | 0.06% | +0.01 |
| SHOP Shopify Inc. Class A | Reduce -0.3% | 0.51% | +0.02 |
| TMDX Transmedics Group Inc. | Reduce -2.0% | 0.84% | +0.02 |
| XOM Exxon Mobil Corp. | Reduce -1.6% | 2.03% | +0.03 |
| IDXX Idexx Laboratories Inc. | Reduce -1.0% | 4.23% | +0.05 |
| ASML ASML Holding NV-NY Reg SHS | Reduce -3.0% | 1.61% | +0.05 |
| JNJ Johnson & Johnson | Reduce -0.0% | 1.60% | +0.12 |
| LLY Eli Lilly & Co. | Reduce -0.7% | 2.38% | +0.62 |
| GOOGL Alphabet Inc. Class A | Reduce -6.3% | 6.22% | +0.88 |
| ISRG Intuitive Surgical Inc. | Reduce -2.3% | 8.18% | +1.33 |
Portfolio Buys Q3 2025 → Q4 2025
| KRYS Krystal Biotech Inc. | Add +31.3% | 2.03% | +0.88 |
| FICO Fair Isaac Corp. | Add +28.1% | 1.76% | +0.50 |
| REGN Regeneron Pharmaceuticals | Add +29.1% | 1.00% | +0.41 |
| AGG iShares Core U.S. Aggregate | New | 0.19% | +0.19 |
| AMGN Amgen Inc. | Add +0.2% | 1.45% | +0.16 |
| VRTX Vertex Pharmaceuticals Inc. | Add +0.3% | 1.38% | +0.15 |
| COHR Coherent Corp. | Add +10.8% | 0.32% | +0.15 |
| UPS United Parcel Service Class B | Add +3.8% | 0.60% | +0.10 |
| CEG Constellation Energy | Add +2.1% | 1.10% | +0.06 |
| ILMN Illumina Inc. | Add +3.1% | 0.18% | +0.05 |
| ASND Ascendis Pharma A/S | New | 0.03% | +0.03 |
| GOOG Alphabet Inc. Class C | Add +1.4% | 0.10% | +0.02 |
| DWAS Invesco Dorsey Wright Smallc | Add +3.0% | 0.32% | +0.01 |
| TSLA Tesla Inc. | Add +13.7% | 0.07% | +0.01 |
| AIVL Wisdomtree US AI Enhanced Va | Add +5.8% | 0.19% | +0.01 |
| IGE iShares North American Natur | Add +3.1% | 0.26% | +0.00 |
| DGRO iShares Core Dividend Growth | Add +4.0% | 0.21% | +0.00 |
| RSP Invesco S&P 500 Equal Weight | Add +3.7% | 0.28% | +0.00 |
| FDVV Fidelity High Dividend ETF | Add +2.7% | 0.27% | +0.00 |
| HDV iShares Core High Dividend E | Add +5.7% | 0.18% | +0.00 |
| IYE iShares U.S. Energy ETF | Add +4.5% | 0.26% | +0.00 |
| FQAL Fidelity Quality Factor ETF | Add +3.1% | 0.23% | +0.00 |
| DON Wisdomtree US Midcap Dividen | Add +5.6% | 0.19% | +0.00 |
| IHI iShares U.S. Medical Devices | Add +2.5% | 0.05% | +0.00 |
| IYJ iShares U.S. Industrials ETF | Add +2.2% | 0.12% | +0.00 |
| IYF iShares US Financials ETF | Add +2.0% | 0.13% | +0.00 |
| IYW iShares Ustechnology ETF | Add +1.6% | 0.13% | 0.00 |
| XLB SS Materials Select Sector | Add +2.3% | 0.12% | 0.00 |
| SLQD iShares 0-5 YR Inv GRD Corp. | Add +3.8% | 0.20% | −0.00 |
| IEF iShares 7-10 Year Treasury B | Add +3.3% | 0.20% | −0.00 |
| IUSG iShares Core S&P U.S. Growth | Add +0.5% | 0.13% | −0.00 |
| REGL Prshrs S&P Mid 400 DVD Arist | Add +4.4% | 0.26% | −0.00 |
| AGGM iShares 1-10 Year U.S. Aggre | Add +3.2% | 0.20% | −0.00 |
| XLY SS Consumer Disc Select Sect | Add +1.9% | 0.12% | −0.00 |
| TIP iShares Tips Bond ETF | Add +3.0% | 0.20% | −0.00 |
| IWF iShares Russell 1000 Growth | Add +0.7% | 0.41% | −0.01 |
| TDIV FT Nasdaq Tech DVD Index FD | Add +0.7% | 0.29% | −0.01 |
| IWP iShares Russell Mid-Cap Grow | Add +3.2% | 0.36% | −0.02 |
| MTUM iShares MSCI USA Momentum Fa | Add +1.8% | 0.39% | −0.02 |
| NFLX Netflix Inc. | Add +0.4% | 0.06% | −0.02 |
| CVX Chevron Corp. | Add +0.4% | 1.37% | −0.07 |
| LMT Lockheed Martin Corp. | Add +0.1% | 1.39% | −0.09 |
| ITW Illinois Tool Works | Add +0.4% | 1.28% | −0.12 |
| PG The Procter & Gamble Co. | Add +0.1% | 1.39% | −0.15 |
| ADP Automatic Data Processing | Add +0.3% | 1.30% | −0.23 |
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q2 2026 | 89 | $816.8M | AAPL, GOOGL, NVDA, ISRG, MA |
| Q1 2026 | 82 | $779.9M | ISRG, AAPL, NVDA, GOOGL, MA |
| Q4 2025 | 86 | $827.1M | ISRG, AAPL, NVDA, GOOGL, MA |
| Q3 2025 | 88 | $798.5M | NVDA, AAPL, ISRG, GOOGL, MA |
| Q2 2025 | 89 | $758.5M | ISRG, NVDA, AAPL, MA, GOOGL |
| Q1 2025 | 85 | $704.5M | ISRG, AAPL, MA, NVDA, GOOGL |
| Q4 2024 | 90 | $725.6M | ISRG, AAPL, NVDA, MA, GOOGL |
| Q3 2024 | 92 | $729.6M | ISRG, AAPL, NVDA, MA, GOOGL |
| Q2 2024 | 89 | $675.6M | ISRG, AAPL, NVDA, GOOGL, MA |
| Q1 2024 | 90 | $646.7M | ISRG, AAPL, NVDA, MA, GOOGL |