Krystal BiotechKRYS
13F holders, Q2 2026 (June 30)422holders +54
86new positions
36sold out
6famous investors
$365.57avg. 13F price*
At the end of Q2 2026, 422 institutions reported holding Krystal Biotech Inc. (KRYS) in their 13F filings, up 54 from Q1 2026. 86 opened new positions and 36 sold out. The largest holders were FMR LLC ($1.6B), BlackRock, Inc. ($1.6B) and Avoro Capital Advisors LLC ($1.1B). 6 famous investors held it, including Ray Dalio (0.1% of Bridgewater Associates's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Fisher (0.0% of Fisher Asset Management's portfolio).
- Company
- Krystal Biotech Inc.
- CUSIP
- 501147102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 86 | $125.1M |
| Exits | 36 | $44.0M |
All 13F filers, Q1 2026 → Q2 2026: 2,893,835 shares bought and 1,221,152 shares sold, net +1,672,683 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 422 holders
| FMR LLC | 0.07% | Add +1.0% | 4,418,197 | $1.6B |
| BlackRock, Inc. | 0.02% | Add +6.1% | 4,181,432 | $1.6B |
| Avoro Capital Advisors LLC | 9.64% | No change | 2,888,888 | $1.1B |
| Vanguard Portfolio Management LLC | 0.03% | Add +8.1% | 1,574,905 | $585.3M |
| State Street Corp. | 0.01% | Add +2.8% | 1,351,158 | $502.2M |
| Vanguard Capital Management LLC | 0.01% | Add +6.5% | 1,240,567 | $461.1M |
| Soleus Capital Management, L.P. | 12.03% | Reduce -18.5% | 939,254 | $349.1M |
| Capital World Investors | 0.03% | Reduce -5.7% | 777,843 | $289.1M |
| Geode Capital Management, LLC | 0.01% | Add +8.5% | 698,993 | $259.8M |
| T. Rowe Price Associates Inc. | 0.03% | Add +41.7% | 687,400 | $255.5M |
| Hood River Capital Management LLC | 1.79% | Add +7.1% | 663,375 | $246.6M |
| Redmile Group, LLC | 15.77% | Reduce -6.2% | 632,005 | $234.9M |
| William Blair Investment Management, LLC | 0.64% | Add +40.0% | 570,153 | $211.9M |
| Frazier Life Sciences Management, L.P. | 3.90% | No change | 481,307 | $178.9M |
| Dimensional Fund Advisors LP | 0.03% | Add +1.5% | 476,038 | $176.9M |
| First Trust Advisors LP | 0.07% | Reduce -7.3% | 324,900 | $120.8M |
| Invesco Ltd. | 0.01% | Add +29.2% | 324,755 | $120.7M |
| Goldman Sachs Group Inc. | 0.01% | Add +39.0% | 298,841 | $111.1M |
| Northern Trust Corp. | 0.01% | Add +12.4% | 283,784 | $105.5M |
| Franklin Resources Inc. | 0.02% | Add +46.1% | 261,917 | $97.3M |
| Norges Bank | 0.01% | — | 259,030 | $96.3M |
| Jupiter Topco LLC | 0.04% | — | 256,665 | $95.4M |
| Bank of America Corp. | 0.01% | Reduce -1.6% | 256,431 | $95.3M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +5.3% | 254,828 | $94.7M |
| Morgan Stanley | 0.00% | Add +12.6% | 235,491 | $87.5M |
| Vestor Capital, LLC | 4.91% | Add +350357.0% | 700,914 | $78.2M |
| Vanguard Fiduciary Trust Co. | 0.02% | Add +5.8% | 189,528 | $70.4M |
| Principal Financial Group Inc. | 0.03% | Add +4.6% | 169,550 | $63.0M |
| Bank of New York Mellon Corp | 0.01% | Add +9.6% | 163,610 | $60.8M |
| Raymond James Financial Inc. | 0.02% | Add +1.7% | 158,675 | $59.0M |
| Woodline Partners LP | 0.17% | No change | 150,616 | $56.0M |
| UBS Group AG | 0.01% | Add +3.3% | 148,316 | $55.1M |
| Nuveen, LLC | 0.01% | Add +2.2% | 146,520 | $54.5M |
| Braidwell LP | 1.84% | Reduce -29.3% | 128,975 | $47.9M |
| Voya Investment Management LLC | 0.05% | Add +14.8% | 124,442 | $46.3M |
| TimesSquare Capital Management, LLC | 0.61% | Reduce -0.7% | 111,545 | $41.5M |
| Pictet Asset Management Holding SA | 0.04% | Reduce -2.6% | 107,798 | $40.1M |
| Public Sector Pension Investment Board | 0.10% | Add +14.3% | 105,515 | $39.2M |
| 1832 Asset Management L.P. | 0.05% | Add +133.1% | 99,300 | $36.9M |
| Westfield Capital Management Co. LP | 0.12% | New | 98,707 | $36.7M |
| BNP Paribas Financial Markets | 0.02% | Reduce -0.9% | 92,234 | $34.3M |
| Handelsbanken Fonder AB | 0.10% | Reduce -1.1% | 90,407 | $33.6M |
| JPMorgan Chase & Co. | 0.00% | Reduce -11.9% | 87,342 | $33.5M |
| Orbimed Advisors LLC | 0.59% | Add +20.4% | 83,200 | $30.9M |
| S Squared Technology, LLC | 8.94% | Reduce -10.1% | 77,545 | $28.8M |
| Bellevue Group AG | 0.61% | Reduce -83.9% | 77,530 | $28.8M |
| Biondo Investment Advisors, LLC | 3.23% | Reduce -1.5% | 70,945 | $26.4M |
| Segall Bryant & Hamill, LLC | 0.29% | Reduce -18.0% | 65,211 | $24.2M |
| Rhumbline Advisers | 0.02% | Reduce -10.1% | 61,236 | $22.8M |
| Renaissance Technologies | 0.03% | Add +521.7% | 59,680 | $22.2M |
| Legal & General Group Plc | 0.00% | Reduce -0.8% | 58,580 | $21.8M |
| C WorldWide Group Holding A/S | 0.52% | Reduce -14.8% | 57,809 | $21.5M |
| Citigroup Inc. | 0.01% | Add +79.7% | 56,016 | $20.8M |
| Bridgewater Associates | 0.08% | Add +17.5% | 54,489 | $20.3M |
| Sei Investments Co. | 0.02% | Add +16.0% | 54,040 | $20.1M |
| Russell Investments Group, Ltd. | 0.02% | Add +100.8% | 52,621 | $19.6M |
| Allspring Global Investments Holdings, LLC | 0.03% | Add +2017.5% | 52,407 | $19.5M |
| Neuberger Berman Group LLC | 0.01% | Add +56.8% | 51,876 | $19.3M |
| Ameriprise Financial Inc. | 0.00% | Reduce -2.1% | 48,790 | $18.1M |
| Palisades Investment Partners, LLC | 5.05% | Add +5.3% | 47,801 | $17.8M |
| Act Capital Management, LLC | 10.93% | Reduce -25.6% | 45,000 | $16.7M |
| Victory Capital Management Inc. | 0.01% | Add +10.4% | 44,935 | $16.7M |
| Federated Hermes, Inc. | 0.02% | Add +23.5% | 43,848 | $16.3M |
| Swiss National Bank | 0.01% | Reduce -3.8% | 41,360 | $15.4M |
| Gilder Gagnon Howe & Co. LLC | 0.15% | Add +0.4% | 40,296 | $15.0M |
| Congress Asset Management Co. | 0.09% | New | 40,134 | $14.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +4.8% | 38,697 | $14.4M |
| SEB Asset Management AB | 0.05% | Reduce -18.6% | 37,731 | $14.0M |
| Wellington Management Group LLP | 0.00% | Add +261.2% | 36,936 | $13.7M |
| Life Cycle Investment Partners Ltd | 0.06% | New | 35,124 | $13.1M |
| Wells Fargo & Company | 0.00% | Add +130.2% | 34,502 | $12.8M |
| New York State Common Retirement Fund | 0.02% | Add +8.6% | 34,033 | $12.6M |
| Granite Investment Partners, LLC | 0.63% | Add +35.2% | 32,837 | $12.2M |
| Prudential Financial Inc. | 0.01% | Add +10.2% | 32,662 | $12.1M |
| Mutual of America Capital Management LLC | 0.12% | Reduce -10.8% | 31,998 | $11.9M |
| Deutsche Bank AG | 0.00% | Add +28.2% | 31,836 | $11.8M |
| Corient Private Wealth LP | 0.02% | Add +767.4% | 30,558 | $11.4M |
| Fisher Asset Management | 0.00% | Reduce -0.4% | 27,676 | $10.3M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -28.3% | 25,867 | $9.6M |
| Aberdeen Group plc | 0.01% | Reduce -16.6% | 25,141 | $9.3M |
| Atle Fund Management AB | 2.40% | Reduce -36.1% | 24,019 | $8.9M |
| California State Teachers Retirement System | 0.01% | Reduce -9.5% | 23,692 | $8.8M |
| Alliancebernstein L.P. | 0.00% | Add +6.6% | 34,039 | $8.8M |
| TD Asset Management Inc | 0.01% | Reduce -47.6% | 22,712 | $8.4M |
| Elmind Capital, LP | 2.05% | No change | 22,000 | $8.2M |
| CANADA LIFE ASSURANCE Co | 0.01% | Add +1.4% | 21,711 | $8.1M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.01% | Add +3.8% | 21,390 | $8.0M |
| Creative Planning | 0.00% | Add +27.5% | 20,318 | $7.6M |
| Bessemer Group Inc. | 0.01% | No change | 20,285 | $7.5M |
| Pinnacle Financial Partners, Inc. | 0.05% | Add +0.3% | 20,243 | $7.5M |
| Tetragon Partners GP Ltd | 1.19% | No change | 19,668 | $7.3M |
| Lisanti Capital Growth, LLC | 1.56% | Add +2.9% | 19,050 | $7.1M |
| GW&K Investment Management, LLC | 0.05% | Reduce -4.9% | 18,295 | $6.8M |
| Thrivent Financial for Lutherans | 0.01% | Add +0.0% | 17,229 | $6.4M |
| Van Eck Associates Corp. | 0.00% | New | 17,071 | $6.3M |
| New York State Teachers Retirement System | 0.01% | Add +7.4% | 16,801 | $6.2M |
| ADAR1 Capital Management, LLC | 0.29% | Reduce -18.0% | 16,420 | $6.1M |
| Cinctive Capital Management LP | 0.24% | Add +469.5% | 16,367 | $6.1M |
| Rhenman & Partners Asset Management AB | 0.57% | Reduce -2.1% | 16,325 | $6.1M |
| Informed Momentum Co LLC | 0.54% | Reduce -1.6% | 16,227 | $6.0M |
"% of holder's portfolio" is KRYS's weight in each manager's 13F, not the share of Krystal Biotech Inc. the manager owns.