BIOS Capital Management, LP

In its 13F for Q4 2024 (holdings as of December 31, 2024, filed February 18, 2025), BIOS Capital Management, LP reported 6 stock positions worth $94.1 million. Its top holding was Actuate Therapeutics (ACTU) at 83.7% of the portfolio, followed by Cognition Therapeutics (CGTX, 4.5%) and Rein Therapeutics (RNTX, 4.1%).

Most Recent 13F
Q2 2026
Location
Fort Worth, TX
CIK
0001813845
Portfolio Value
$94.1M (Q4 2024)
SEC Filing
0001104659-25-014450 ↗ filed Feb 18, 2025

Holdings Value

0$20.0M$40.0M$60.0M$80.0M$100.0M Q4 2024: $94.1M $94.1M Q4 2024 Q1 2025: $79.2M Q1 2025 Q2 2025: $72.6M Q2 2025 Q3 2025: $88.9M Q3 2025 Q4 2025: $82.6M Q4 2025 Q1 2026: $52.9M Q1 2026 Q2 2026: $41.7M Q2 2026

Holdings 6 stocks · $94.1M

ACTU Actuate Therapeutics Inc. 83.69% 9,893,651 $78.8M —
CGTX Cognition Therapeutics Inc. 4.47% 6,000,000 $4.2M —
RNTX Rein Therapeutics Inc. filed as AILERON THERAPEUTICS INC 4.13% 1,690,751 $3.9M —
LTRN Lantern Pharma Inc. 4.09% 1,207,709 $3.9M —
INAB IN8BIO Inc. 2.35% 8,600,001 $2.2M —
IRD Opus Genetics Inc. 1.26% 995,249 $1.2M —

Portfolio Sells Q4 2024

No earlier filing to compare with.

Portfolio Buys Q4 2024

No earlier filing to compare with.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 6$41.7MACTU, IRD, CGTX, RNTX, LTRN
Q1 2026 6$52.9MACTU, IRD, CGTX, RNTX, LTRN
Q4 2025 6$82.6MACTU, CGTX, IRD, LTRN, RNTX
Q3 2025 6$88.9MACTU, CGTX, IRD, LTRN, RNTX
Q2 2025 6$72.6MACTU, IRD, LTRN, RNTX, CGTX
Q1 2025 6$79.2MACTU, LTRN, RNTX, CGTX, INAB
Q4 2024Amended 6$94.1MACTU, CGTX, RNTX, LTRN, INAB