BIOS Capital Management, LP

In its 13F for Q1 2025 (holdings as of March 31, 2025, filed May 14, 2025), BIOS Capital Management, LP reported 6 stock positions worth $79.2 million. Its top holding was Actuate Therapeutics (ACTU) at 84.6% of the portfolio, followed by Lantern Pharma (LTRN, 5.4%) and Rein Therapeutics (RNTX, 3.8%). Its holdings were unchanged from Q4 2024.

Most Recent 13F
Q2 2026
Location
Fort Worth, TX
CIK
0001813845
Portfolio Value
$79.2M (Q1 2025)
SEC Filing
0001104659-25-048606 ↗ filed May 14, 2025

Holdings Value

0$20.0M$40.0M$60.0M$80.0M$100.0M Q4 2024: $94.1M Q4 2024 Q1 2025: $79.2M $79.2M Q1 2025 Q2 2025: $72.6M Q2 2025 Q3 2025: $88.9M Q3 2025 Q4 2025: $82.6M Q4 2025 Q1 2026: $52.9M Q1 2026 Q2 2026: $41.7M Q2 2026

Holdings 6 stocks · $79.2M

ACTU Actuate Therapeutics Inc. 84.59% 9,893,651 $67.0M No change
LTRN Lantern Pharma Inc. 5.40% 1,207,709 $4.3M No change
RNTX Rein Therapeutics Inc. 3.78% 1,690,751 $3.0M No change
CGTX Cognition Therapeutics Inc. 3.19% 6,000,000 $2.5M No change
INAB IN8BIO Inc. 1.80% 8,600,001 $1.4M No change
IRD Opus Genetics Inc. 1.23% 995,249 $977K No change

Portfolio Sells Q4 2024 → Q1 2025

None this quarter.

Portfolio Buys Q4 2024 → Q1 2025

None this quarter.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 6$41.7MACTU, IRD, CGTX, RNTX, LTRN
Q1 2026 6$52.9MACTU, IRD, CGTX, RNTX, LTRN
Q4 2025 6$82.6MACTU, CGTX, IRD, LTRN, RNTX
Q3 2025 6$88.9MACTU, CGTX, IRD, LTRN, RNTX
Q2 2025 6$72.6MACTU, IRD, LTRN, RNTX, CGTX
Q1 2025 6$79.2MACTU, LTRN, RNTX, CGTX, INAB
Q4 2024Amended 6$94.1MACTU, CGTX, RNTX, LTRN, INAB