Blue Water Life Science Advisors, LP

In its 13F for Q1 2026 (holdings as of March 31, 2026, filed May 14, 2026), Blue Water Life Science Advisors, LP reported 10 stock positions worth $124.7 million. Its top holding was 10X Genomics Class A (TXG) at 18.6% of the portfolio, followed by Guardant Health (GH, 17.9%) and Caredx (CDNA, 13.0%). Compared with Q4 2025, it opened 2 new positions, sold out of 1, added to 3 and reduced 4. The biggest buy was a new position in 10X Genomics Class A (TXG) and the biggest sale Natera (NTRA, shares −68%).

Most Recent 13F
Q2 2026
Location
LARKSPUR, CA
CIK
0001789778
Portfolio Value
$124.7M (Q1 2026)
SEC Filing
0001420506-26-001003 ↗ filed May 14, 2026

Holdings Value

0$50.0M$100.0M$150.0M$200.0M Q1 2024: $106.3M Q1 2024 Q2 2024: $102.8M Q2 2024 Q3 2024: $113.7M Q3 2024 Q4 2024: $112.9M Q4 2024 Q1 2025: $100.9M Q1 2025 Q2 2025: $126.3M Q2 2025 Q3 2025: $109.6M Q3 2025 Q4 2025: $159.3M Q4 2025 Q1 2026: $124.7M $124.7M Q1 2026 Q2 2026: $158.8M Q2 2026

Holdings 10 stocks · $124.7M
TXG 10X Genomics Inc. Class A 18.56% 1,090,000 $23.1M New
GH Guardant Health Inc. 17.94% 242,247 $22.4M Reduce -31.8%
CDNA Caredx Inc. 13.02% 935,000 $16.2M Add +83.3%
ADPT Adaptive Biotechnologies 11.24% 1,010,145 $14.0M Reduce -42.8%
TWST Twist Bioscience Corp. 10.52% 276,000 $13.1M Reduce -27.9%
PSNL Personalis Inc. 8.56% 1,676,300 $10.7M No change
NTRA Natera Inc. 7.18% 44,794 $9.0M Reduce -68.3%
QTRX Quanterix Corp. 6.05% 2,142,147 $7.5M Add +2.4%
TEM Tempus AI Inc. Class A 5.67% 156,412 $7.1M Add +81.0%
BLLN Billiontoone Inc. Class A 1.27% 20,000 $1.6M New

Portfolio Sells Q4 2025 → Q1 2026
NTRA Natera Inc. Reduce -68.3% 7.18% −13.16
ADPT Adaptive Biotechnologies Reduce -42.8% 11.24% −6.75
GRAL Grail Inc. Sold out 0.00% −5.32
GH Guardant Health Inc. Reduce -31.8% 17.94% −4.82
TWST Twist Bioscience Corp. Reduce -27.9% 10.52% +2.89

Portfolio Buys Q4 2025 → Q1 2026
TXG 10X Genomics Inc. Class A New 18.56% +18.56
CDNA Caredx Inc. Add +83.3% 13.02% +6.98
TEM Tempus AI Inc. Class A Add +81.0% 5.67% +2.47
BLLN Billiontoone Inc. Class A New 1.27% +1.27
QTRX Quanterix Corp. Add +2.4% 6.05% −2.31

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 9$158.8MCDNA, TXG, PSNL, ADPT, GH
Q1 2026 10$124.7MTXG, GH, CDNA, ADPT, TWST
Q4 2025 9$159.3MGH, NTRA, ADPT, PSNL, QTRX
Q3 2025 7$109.6MADPT, GH, NTRA, PSNL, CDNA
Q2 2025 8$126.3MNTRA, ADPT, GH, CDNA, TXG
Q1 2025 7$100.9MGH, NTRA, ADPT, CDNA, AKYA
Q4 2024 9$112.9MNTRA, GH, CDNA, ADPT, AKYA
Q3 2024 8$113.7MNTRA, CDNA, EXAS, AKYA, ADPT
Q2 2024 8$102.8MNTRA, GH, AKYA, CDNA, TXG
Q1 2024 8$106.3MNTRA, AKYA, GH, TXG, QTRX