Matrix Capital Management Company, LP

In its 13F for Q3 2025 (holdings as of September 30, 2025, filed November 13, 2025), Matrix Capital Management Company, LP reported 3 stock positions worth $106.7 million. Its top holding was Maze Therapeutics (MAZE) at 40.2% of the portfolio, followed by Aura Biosciences (AURA, 40.1%) and Zentalis Pharmaceuticals (ZNTL, 19.7%). Compared with Q2 2025, it sold out of 1 and reduced 1. The biggest sale was an exit from Globalfoundries (GFS).

Most Recent 13F
Q2 2026
Location
Portsmouth, NH
CIK
0001410830
Portfolio Value
$106.7M (Q3 2025)
SEC Filing
0001172661-25-004764 ↗ filed Nov 13, 2025

Holdings Value

0$5.0B$10.0B$15.0B Q1 2024: $10.8B Q1 2024 Q2 2024: $13.1B Q2 2024 Q3 2024: $2.1B Q3 2024 Q4 2024: $2.2B Q4 2024 Q1 2025: $347.2M Q1 2025 Q2 2025: $222.8M Q2 2025 Q3 2025: $106.7M $106.7M Q3 2025 Q4 2025: $57.6M Q4 2025 Q1 2026: $46.3M Q1 2026 Q2 2026: $0 Q2 2026

Holdings 3 stocks · $106.7M

MAZE Maze Therapeutics Inc. 40.17% 1,653,684 $42.9M Reduce -33.5%
AURA Aura Biosciences Inc. 40.08% 6,922,870 $42.8M No change
ZNTL Zentalis Pharmaceuticals Inc. 19.75% 13,959,973 $21.1M No change

Portfolio Sells Q2 2025 → Q3 2025

GFS Globalfoundries Inc. Sold out 0.00% −59.59
MAZE Maze Therapeutics Inc. Reduce -33.5% 40.17% +26.48

Portfolio Buys Q2 2025 → Q3 2025

None this quarter.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 0$0
Q1 2026 1$46.3MAURA
Q4 2025 2$57.6MAURA, MAZE
Q3 2025 3$106.7MMAZE, AURA, ZNTL
Q2 2025 4$222.8MGFS, AURA, MAZE, ZNTL
Q1 2025 4$347.2MGFS, AURA, MAZE, ZNTL
Q4 2024 5$2.2BALTR, GFS, PRM, AURA, ZNTL
Q3 2024 7$2.1BALTR, GFS, PRM, AURA, ZNTL
Q2 2024 23$13.1BNVDA, QCOM, TDG, ALTR, MRVL
Q1 2024 23$10.8BNVDA, TDG, QCOM, ALTR, MRVL