Monashee Investment Management LLC
In its 13F for Q4 2025 (holdings as of December 31, 2025, filed February 12, 2026), Monashee Investment Management LLC reported 37 stock positions worth $169.3 million. Its top holding was Structure Therapeutics (GPCR) at 9.2% of the portfolio, followed by Medline Class A (MDLN, 7.4%) and Sofi Technologies (SOFI, 6.2%). Compared with Q3 2025, it opened 26 new positions, sold out of 47, added to 3 and reduced 8. The biggest buy was a new position in Medline Class A (MDLN) and the biggest sale an exit from Forward Industries (FWDI).
- Most Recent 13F
- Q2 2026
- Location
- Boston, MA
- CIK
- 0001627608
- Portfolio Value
- $169.3M (Q4 2025)
- SEC Filing
- 0001172661-26-000650 ↗ filed Feb 12, 2026
Holdings Value
Holdings 37 stocks · $169.3M
| GPCR Structure Therapeutics Inc. | 9.24% | 225,000 | $15.6M | Add +12.5% |
| MDLN Medline Inc. Class A | 7.44% | 300,000 | $12.6M | New |
| SOFI Sofi Technologies Inc. | 6.19% | 400,000 | $10.5M | New |
| ULS Ul Solutions Inc. Class A | 6.06% | 130,000 | $10.3M | New |
| INSM Insmed Inc. | 5.14% | 50,000 | $8.7M | New |
| TERN Terns Pharmaceuticals Inc. | 4.71% | 197,313 | $8.0M | New |
| KYMR Kymera Therapeutics Inc. | 4.60% | 100,000 | $7.8M | New |
| MIAX Miami International Holdings | 4.59% | 175,000 | $7.8M | Add +16.7% |
| BBIO Bridgebio Pharma Inc. | 4.52% | 100,000 | $7.6M | Reduce -50.0% |
| SLDB Solid Biosciences Inc. | 4.50% | 1,349,771 | $7.6M | New |
| LGN Legence Corp. Class A | 3.51% | 137,940 | $5.9M | Reduce -8.0% |
| IMNM Immunome Inc. | 3.49% | 274,861 | $5.9M | New |
| ITT Itt Inc. | 3.29% | 32,067 | $5.6M | New |
| CMPX Compass Therapeutics Inc. | 3.17% | 1,000,000 | $5.4M | Reduce -20.0% |
| CYTK Cytokinetics Inc. | 2.82% | 75,000 | $4.8M | Reduce -25.0% |
| WLTH Wealthfront Corp. | 2.41% | 300,000 | $4.1M | New |
| NKTR Nektar Therapeutics | 2.35% | 94,134 | $4.0M | New |
| ADT Adt Inc. | 1.91% | 400,000 | $3.2M | Reduce -11.1% |
| EVMN Evommune Inc. | 1.85% | 183,239 | $3.1M | New |
| GOSS Gossamer Bio Inc. | 1.83% | 1,000,000 | $3.1M | New |
| LMRI Lumexa Imaging Holdings Inc. | 1.64% | 150,000 | $2.8M | New |
| ENGN Engene Holdings Inc. | 1.57% | 295,000 | $2.7M | New |
| AMBQ Ambiq Micro Inc. | 1.43% | 85,089 | $2.4M | Reduce -57.5% |
| DYN Dyne Therapeutics Inc. | 1.32% | 114,525 | $2.2M | New |
| WYFI Whitefiber Inc. | 1.31% | 140,000 | $2.2M | Reduce -60.6% |
| AERO Grupo Aeromexico Sab DE CV | 1.19% | 91,619 | $2.0M | New |
| EVAC.U Eqv Ventures Acquisition Cor | 1.18% | 198,313 | $2.0M | Reduce -11.9% |
| KYTX Kyverna Therapeutics Inc. | 1.08% | 195,000 | $1.8M | New |
| IMTX Immatics NV | 0.99% | 160,336 | $1.7M | New |
| CTNM Contineum Therapeutics Inc. Class A | 0.93% | 137,430 | $1.6M | New |
| DNLI Denali Therapeutics Inc. | 0.89% | 91,620 | $1.5M | New |
| VERA Vera Therapeutics Inc. | 0.69% | 22,905 | $1.2M | New |
| LPTH Lightpath Technologies Inc. Class A | 0.64% | 100,000 | $1.1M | New |
| BDSX Biodesix Inc. | 0.45% | 112,344 | $764K | Add +12.3% |
| TARA Protara Therapeutic Inc. | 0.39% | 125,000 | $666K | New |
| IMA Imagenebio Inc. | 0.37% | 91,621 | $632K | New |
| IBIO Ibio Inc. | 0.31% | 274,862 | $530K | New |
Other holdings (3): bonds, preferreds, convertibles and warrants · $8.2M (not counted above)
| Security | Class | Shares / Principal | Value | Change |
|---|---|---|---|---|
| SOUTHERN CO (SO 7.125 12/15/28 A) | UNIT 12/15/2028 | 75,877 | $3.8M | New |
| NOVANTA INC (NOVT 6.5 11/01/28) | UNIT 11/01/2028 | 55,962 | $3.1M | New |
| GOSSAMER BIO INC (GOSS 5 06/01/27) | NOTE 5.000% 6/0 · principal | 1,874,000 | $1.3M | Add +87.4% |
Total filed on the 13F, all lines: $177.5M.
Portfolio Sells Q3 2025 → Q4 2025
| FWDI Forward Industries Inc. | Sold out | 0.00% | −5.34 |
| FIGR Figure Technology Solut Class A | Sold out | 0.00% | −3.75 |
| WYFI Whitefiber Inc. | Reduce -60.6% | 1.31% | −3.66 |
| NTSK Netskope Inc. Class A | Sold out | 0.00% | −3.51 |
| CRBG Corebridge Financial Inc. | Sold out | 0.00% | −3.30 |
| LTM Latam Airlines Group SA-ADR | Sold out | 0.00% | −3.15 |
| WBI Waterbridge Infrastruc Class A | Sold out | 0.00% | −3.12 |
| WAY Waystar Holding Corp. | Sold out | 0.00% | −2.93 |
| BTBT Bit Digital Inc. | Sold out | 0.00% | −2.32 |
| NBIS Nebius Group NV | Sold out | 0.00% | −2.31 |
| SFD Smithfield Foods Inc. | Sold out | 0.00% | −2.18 |
| NWS News Corp. Class B | Sold out | 0.00% | −2.14 |
| FOX Fox Corp. Class B | Sold out | 0.00% | −2.07 |
| KLAR Klarna Group PLC | Sold out | 0.00% | −1.89 |
| STUB Stubhub Holdings Inc. Class A | Sold out | 0.00% | −1.74 |
| VIA Via Transportation Inc. Class A | Sold out | 0.00% | −1.73 |
| AMBQ Ambiq Micro Inc. | Reduce -57.5% | 1.43% | −1.65 |
| BLSH Bullish | Sold out | 0.00% | −1.64 |
| SLDE Slide Insurance Holdings Inc. | Sold out | 0.00% | −1.42 |
| CRWV Coreweave Inc. Class A | Sold out | 0.00% | −1.41 |
| CRCL Circle Internet Group Inc. | Sold out | 0.00% | −1.37 |
| FIG Figma Inc. Class A | Sold out | 0.00% | −1.34 |
| HNGE Hinge Health Inc. Class A | Sold out | 0.00% | −1.26 |
| BRCB Black Rock Coffee Bar Inc. Class A | Sold out | 0.00% | −1.23 |
| QURE Uniqure NV | Sold out | 0.00% | −1.20 |
| MIR Mirion Technologies Inc. | Sold out | 0.00% | −1.20 |
| UUUU Energy Fuels Inc. | Sold out | 0.00% | −1.19 |
| CHYM Chime Financial Inc. Class A | Sold out | 0.00% | −1.14 |
| RNAM Avidity Biosciences Inc. | Sold out | 0.00% | −1.12 |
| IMRX Immuneering Corp. Class A | Sold out | 0.00% | −1.08 |
| CTRE Caretrust REIT Inc. | Sold out | 0.00% | −1.07 |
| CAEP Cantor Equity Partners III-A | Sold out | 0.00% | −1.06 |
| PTRN Pattern Group Inc. Class A | Sold out | 0.00% | −1.06 |
| AIRO Airo Group Holdings Inc. | Sold out | 0.00% | −0.99 |
| CIFR Cipher Digital Inc. | Sold out | 0.00% | −0.97 |
| BBIO Bridgebio Pharma Inc. | Reduce -50.0% | 4.52% | −0.84 |
| GEMI Gemini Space Station Inc. Class A | Sold out | 0.00% | −0.74 |
| PEPG Pepgen Inc. | Sold out | 0.00% | −0.71 |
| CEPT Cantor Equity Partners Class A | Sold out | 0.00% | −0.69 |
| KVYO Klaviyo Inc. Class A | Sold out | 0.00% | −0.57 |
| HLLY Holley Inc. | Sold out | 0.00% | −0.57 |
| CEPF Cantor Equity Partners Class A | Sold out | 0.00% | −0.53 |
| NIQ Niq Global Intelligence PLC | Sold out | 0.00% | −0.49 |
| RIG Transocean Ltd. | Sold out | 0.00% | −0.48 |
| MH McGraw Hill Inc. | Sold out | 0.00% | −0.39 |
| LBRX LB Pharmaceuticals Inc. | Sold out | 0.00% | −0.33 |
| CARL Carlsmed Inc. | Sold out | 0.00% | −0.28 |
| SI Shoulder Innovations Inc. | Sold out | 0.00% | −0.26 |
| AMLX Amylyx Pharmaceuticals Inc. | Sold out | 0.00% | −0.21 |
| ADT Adt Inc. | Reduce -11.1% | 1.91% | −0.11 |
Portfolio Buys Q3 2025 → Q4 2025
| MDLN Medline Inc. Class A | New | 7.44% | +7.44 |
| GPCR Structure Therapeutics Inc. | Add +12.5% | 9.24% | +6.36 |
| SOFI Sofi Technologies Inc. | New | 6.19% | +6.19 |
| ULS Ul Solutions Inc. Class A | New | 6.06% | +6.06 |
| INSM Insmed Inc. | New | 5.14% | +5.14 |
| TERN Terns Pharmaceuticals Inc. | New | 4.71% | +4.71 |
| KYMR Kymera Therapeutics Inc. | New | 4.60% | +4.60 |
| SLDB Solid Biosciences Inc. | New | 4.50% | +4.50 |
| IMNM Immunome Inc. | New | 3.49% | +3.49 |
| ITT Itt Inc. | New | 3.29% | +3.29 |
| WLTH Wealthfront Corp. | New | 2.41% | +2.41 |
| NKTR Nektar Therapeutics | New | 2.35% | +2.35 |
| EVMN Evommune Inc. | New | 1.85% | +1.85 |
| GOSS Gossamer Bio Inc. | New | 1.83% | +1.83 |
| LMRI Lumexa Imaging Holdings Inc. | New | 1.64% | +1.64 |
| ENGN Engene Holdings Inc. | New | 1.57% | +1.57 |
| MIAX Miami International Holdings | Add +16.7% | 4.59% | +1.48 |
| DYN Dyne Therapeutics Inc. | New | 1.32% | +1.32 |
| AERO Grupo Aeromexico Sab DE CV | New | 1.19% | +1.19 |
| KYTX Kyverna Therapeutics Inc. | New | 1.08% | +1.08 |
| IMTX Immatics NV | New | 0.99% | +0.99 |
| CTNM Contineum Therapeutics Inc. Class A | New | 0.93% | +0.93 |
| DNLI Denali Therapeutics Inc. | New | 0.89% | +0.89 |
| VERA Vera Therapeutics Inc. | New | 0.69% | +0.69 |
| LPTH Lightpath Technologies Inc. Class A | New | 0.64% | +0.64 |
| TARA Protara Therapeutic Inc. | New | 0.39% | +0.39 |
| IMA Imagenebio Inc. | New | 0.37% | +0.37 |
| IBIO Ibio Inc. | New | 0.31% | +0.31 |
| BDSX Biodesix Inc. | Add +12.3% | 0.45% | +0.06 |
Notes & Other Activity Q3 2025 → Q4 2025
| SOUTHERN CO (SO 7.125 12/15/28 A) | UNIT 12/15/2028 | New | 75,877 | $3.8M |
| BRUKER CORP (BRKR 6.375 09/01/28) | 6.375 PREF SER A | Sold out | 14,000 | $3.8Mbefore exit |
| NOVANTA INC (NOVT 6.5 11/01/28) | UNIT 11/01/2028 | New | 55,962 | $3.1M |
| EVOLENT HEALTH INC | DEBT 4.500% 8/1 · principal | Sold out | 2,000,000 | $2.0Mbefore exit |
| GOSSAMER BIO INC (GOSS 5 06/01/27) | NOTE 5.000% 6/0 · principal | Add +87.4% | 1,874,000 | $1.3M |
Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q2 2026 | 17 | $41.4M | SLDB, DLR, SYRE, ADT, TNGX |
| Q1 2026 | 41 | $154.8M | TERN, MDLN, NRG, FPS, SLDB |
| Q4 2025 | 37 | $169.3M | GPCR, MDLN, SOFI, ULS, INSM |
| Q3 2025 | 58 | $194.0M | BBIO, FWDI, WYFI, FIGR, NTSK |
| Q2 2025 | 36 | $181.8M | LLY, CORZ, KTOS, BBIO, SLDB |
| Q1 2025 | 41 | $826.9M | IVV, VOO, VEA, IEFA, VWO |
| Q4 2024 | 34 | $719.5M | IVV, VOO, VEA, IEFA, VWO |
| Q3 2024 | 103 | $903.5M | IVV, VOO, VEA, IEFA, VWO |
| Q2 2024 | 72 | $766.6M | IVV, VOO, VEA, IEFA, VWO |
| Q1 2024 | 99 | $835.9M | IVV, VOO, VEA, IEFA, VWO |