Amylyx PharmaceuticalsAMLX
13F holders, Q2 2026 (June 30)206holders +35
46new positions
13sold out
4famous investors
$17.97avg. 13F price*
At the end of Q2 2026, 206 institutions reported holding Amylyx Pharmaceuticals Inc. (AMLX) in their 13F filings, up 35 from Q1 2026. 46 opened new positions and 13 sold out. The largest holders were FMR LLC ($300.4M), BlackRock, Inc. ($158.5M) and Perceptive Advisors LLC ($149.7M). 4 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Amylyx Pharmaceuticals Inc.
- CUSIP
- 03237H101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 46 | $87.8M |
| Exits | 13 | $5.1M |
All 13F filers, Q1 2026 → Q2 2026: 11,121,818 shares bought and 10,734,061 shares sold, net +387,757 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 206 holders
| FMR LLC | 0.01% | Add +0.6% | 16,727,909 | $300.4M |
| BlackRock, Inc. | 0.00% | Reduce -0.0% | 8,827,085 | $158.5M |
| Perceptive Advisors LLC | 2.33% | Add +0.6% | 8,334,882 | $149.7M |
| TCG Crossover Management, LLC | 2.70% | No change | 6,243,812 | $112.1M |
| Commodore Capital LP | 6.04% | No change | 5,650,000 | $101.5M |
| Jupiter Topco LLC | 0.04% | — | 5,236,102 | $94.0M |
| Saturn V Capital Management LP | 11.91% | Add +6.3% | 4,624,101 | $83.0M |
| Vanguard Capital Management LLC | 0.00% | Add +2.0% | 4,224,224 | $75.9M |
| Morgan Stanley | 0.00% | Add +43.9% | 3,130,808 | $56.2M |
| Driehaus Capital Management LLC | 0.32% | Add +1.7% | 3,036,970 | $54.5M |
| First Light Asset Management, LLC | 3.30% | Reduce -5.3% | 3,023,256 | $54.3M |
| Franklin Resources Inc. | 0.01% | Add +30.4% | 2,950,225 | $53.0M |
| Goldman Sachs Group Inc. | 0.01% | Add +8.8% | 2,858,239 | $51.3M |
| State Street Corp. | 0.00% | Add +10.2% | 2,603,337 | $46.8M |
| Geode Capital Management, LLC | 0.00% | Add +5.6% | 2,335,315 | $41.9M |
| JPMorgan Chase & Co. | 0.00% | Add +1067.2% | 1,863,650 | $34.9M |
| Adage Capital Partners Gp, L.L.C. | 0.05% | Reduce -46.6% | 1,900,000 | $34.1M |
| Siren, L.L.C. | 0.54% | Add +20.4% | 1,480,586 | $26.6M |
| Eventide Asset Management, LLC | 0.32% | Reduce -12.3% | 1,327,536 | $23.8M |
| 683 Capital Management, LLC | 2.21% | Reduce -16.4% | 1,279,512 | $23.0M |
| Vanguard Portfolio Management LLC | 0.00% | Add +12.4% | 1,061,534 | $19.1M |
| Alyeska Investment Group, L.P. | 0.05% | New | 1,053,015 | $18.9M |
| Almitas Capital LLC | 4.20% | Reduce -54.1% | 974,881 | $17.5M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -0.1% | 902,463 | $16.2M |
| Jones Hill Capital LP | 3.41% | Reduce -44.1% | 894,058 | $16.1M |
| Woodline Partners LP | 0.05% | Add +0.1% | 846,387 | $15.2M |
| Northern Trust Corp. | 0.00% | Add +6.7% | 831,740 | $14.9M |
| Bank of America Corp. | 0.00% | Reduce -38.2% | 821,841 | $14.8M |
| Boxer Capital Management, LLC | 1.08% | No change | 800,000 | $14.4M |
| Aberdeen Group plc | 0.02% | New | 737,670 | $13.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.2% | 725,030 | $13.0M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.02% | Reduce -17.0% | 721,002 | $12.9M |
| Great Point Partners LLC | 2.96% | Reduce -60.0% | 700,000 | $12.6M |
| Balyasny Asset Management L.P. | 0.02% | Reduce -38.1% | 684,974 | $12.3M |
| Qube Research & Technologies Ltd | 0.01% | Reduce -3.0% | 681,389 | $12.2M |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +6.3% | 623,078 | $11.2M |
| Two Sigma Investments, LP | 0.01% | Add +266.4% | 593,435 | $10.7M |
| Deutsche Bank AG | 0.00% | Reduce -56.0% | 557,937 | $10.0M |
| Rock Springs Capital Management LP | 0.44% | No change | 499,764 | $9.0M |
| ADAR1 Capital Management, LLC | 0.42% | Reduce -50.6% | 494,378 | $8.9M |
| Nantahala Capital Management, LLC | 0.53% | Reduce -9.2% | 486,684 | $8.7M |
| Federated Hermes, Inc. | 0.01% | Add +27.1% | 462,205 | $8.3M |
| Nearwater Capital Markets, Ltd | 0.13% | New | 425,000 | $7.6M |
| Parkman Healthcare Partners LLC | 0.74% | Reduce -35.8% | 398,782 | $7.2M |
| HighVista Strategies LLC | 1.58% | Add +9.7% | 386,080 | $6.9M |
| Stempoint Capital LP | 1.19% | Reduce -42.6% | 384,304 | $6.9M |
| Logos Global Management LP | 0.27% | Reduce -50.0% | 350,000 | $6.3M |
| Trexquant Investment LP | 0.04% | New | 349,439 | $6.3M |
| Nuveen, LLC | 0.00% | Add +24.8% | 330,521 | $5.9M |
| Ensign Peak Advisors, Inc | 0.01% | New | 305,441 | $5.5M |
| iA Global Asset Management Inc. | 0.06% | Reduce -0.3% | 303,786 | $5.5M |
| Jane Street Group, LLC | 0.00% | New | 299,565 | $5.4M |
| Tetragon Partners GP Ltd | 0.87% | Reduce -6.3% | 297,926 | $5.4M |
| Jupiter Asset Management Ltd. | 0.02% | Reduce -53.6% | 274,944 | $4.9M |
| Bank of New York Mellon Corp | 0.00% | Add +9.3% | 274,435 | $4.9M |
| UBS Group AG | 0.00% | Reduce -16.2% | 271,881 | $4.9M |
| First Trust Advisors LP | 0.00% | New | 254,587 | $4.6M |
| SummitTX Capital, L.P. | 0.11% | Add +0.3% | 227,690 | $4.1M |
| Wellington Management Group LLP | 0.00% | Reduce -11.9% | 212,842 | $3.8M |
| Cormorant Asset Management, LP | 0.18% | Reduce -42.9% | 200,000 | $3.6M |
| Aldebaran Capital, LLC | 2.64% | Reduce -1.0% | 195,892 | $3.5M |
| Walleye Capital LLC | 0.02% | Add +202.4% | 186,588 | $3.4M |
| Orbimed Advisors LLC | 0.06% | New | 183,400 | $3.3M |
| Citadel Advisors | 0.00% | Reduce -56.6% | 178,686 | $3.2M |
| D. E. Shaw & Co. | 0.00% | Add +134.8% | 174,285 | $3.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +10.4% | 173,407 | $3.1M |
| Acuta Capital Partners, LLC | 2.10% | Add +11.3% | 168,115 | $3.0M |
| Norges Bank | 0.00% | — | 159,900 | $2.9M |
| Alpha Wave Global, LP | 0.04% | Add +9.2% | 155,422 | $2.8M |
| T. Rowe Price Associates Inc. | 0.00% | Add +19.5% | 145,133 | $2.6M |
| Swiss National Bank | 0.00% | Add +10.7% | 144,200 | $2.6M |
| PFM Health Sciences, LP | 0.22% | Reduce -1.1% | 143,700 | $2.6M |
| Invesco Ltd. | 0.00% | Reduce -18.5% | 139,942 | $2.5M |
| Wells Fargo & Company | 0.00% | Add +70.7% | 128,164 | $2.3M |
| Ameriprise Financial Inc. | 0.00% | New | 125,484 | $2.3M |
| Lighthouse Investment Partners, LLC | 0.07% | New | 122,909 | $2.2M |
| Ikarian Capital, LLC | 0.35% | New | 117,500 | $2.1M |
| Rhumbline Advisers | 0.00% | Add +4.1% | 112,920 | $2.0M |
| Alps Advisors Inc. | 0.01% | Add +25.0% | 112,447 | $2.0M |
| Elmind Capital, LP | 0.51% | No change | 112,000 | $2.0M |
| Campbell & CO Investment Adviser LLC | 0.10% | Add +85.5% | 100,963 | $1.8M |
| Affinity Asset Advisors, LLC | 0.09% | New | 98,999 | $1.8M |
| Russell Investments Group, Ltd. | 0.00% | Add +47.6% | 87,574 | $1.6M |
| Quantinno Capital Management LP | 0.00% | New | 80,850 | $1.5M |
| Alliancebernstein L.P. | 0.00% | Add +29.2% | 104,400 | $1.5M |
| California State Teachers Retirement System | 0.00% | Add +22.9% | 79,872 | $1.4M |
| 1492 Capital Management LLC | 0.42% | New | 79,751 | $1.4M |
| Citigroup Inc. | 0.00% | Add +116.1% | 68,684 | $1.2M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -14.1% | 66,804 | $1.2M |
| State of Wisconsin Investment Board | 0.00% | Reduce -15.0% | 61,278 | $1.1M |
| Corient Private Wealth LP | 0.00% | New | 59,322 | $1.1M |
| Moody Aldrich Partners LLC | 0.19% | New | 57,802 | $1.0M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | Add +31.6% | 56,948 | $1.0M |
| Legal & General Group Plc | 0.00% | Add +1.3% | 56,477 | $1.0M |
| Barclays PLC | 0.00% | Reduce -94.2% | 56,258 | $1.0M |
| MetLife Investment Management, LLC | 0.00% | Add +8.0% | 55,700 | $1.0M |
| SG Americas Securities, LLC | 0.00% | New | 55,321 | $994K |
| Hudson Bay Capital Management LP | 0.00% | New | 50,000 | $898K |
| Vanguard Global Advisers, LLC | 0.00% | No change | 47,851 | $859K |
| Fox Run Management, L.L.C. | 0.13% | New | 44,817 | $805K |
"% of holder's portfolio" is AMLX's weight in each manager's 13F, not the share of Amylyx Pharmaceuticals Inc. the manager owns.