Politan Capital Management LP
In its 13F for Q3 2025 (holdings as of September 30, 2025, filed November 14, 2025), Politan Capital Management LP reported 21 stock positions worth $1.1 billion. Its top holding was Masimo (MASI) at 61.5% of the portfolio, followed by Centene (CNC, 24.0%) and Azenta (AZTA, 12.1%). Compared with Q2 2025, it opened 2 new positions, added to 13 and reduced 4. The biggest buy was a new position in Vanguard Russell 2000 ETF (VTWO) and the biggest sale Centene (CNC, shares −8%).
- Most Recent 13F
- Q2 2026
- Location
- NEW YORK, NY
- CIK
- 0001885245
- Portfolio Value
- $1.1B (Q3 2025)
- SEC Filing
- 0000902664-25-005062 ↗ filed Nov 14, 2025
Holdings Value
Holdings 21 stocks · $1.1B
| MASI Masimo Corp. | 61.54% | 4,589,648 | $677.2M | Reduce -2.7% |
| CNC Centene Corp. | 24.02% | 7,409,084 | $264.4M | Reduce -7.9% |
| AZTA Azenta Inc. | 12.05% | 4,616,787 | $132.6M | No change |
| IWM iShares Russell 2000 ETF | 0.39% | 17,569 | $4.3M | Reduce -9.7% |
| VTWO Vanguard Russell 2000 ETF | 0.29% | 32,315 | $3.2M | New |
| CSGP Costar Group Inc. | 0.21% | 27,635 | $2.3M | Add +11.0% |
| PFGC Performance Food Group Co. | 0.16% | 17,121 | $1.8M | Add +17.9% |
| APD Air Products & Chemicals Inc. | 0.13% | 5,202 | $1.4M | Add +12.7% |
| DIS The Walt Disney Co. filed as DISNEY WALT CO | 0.13% | 12,296 | $1.4M | Add +4.0% |
| MIDD Middleby Corp. | 0.12% | 10,215 | $1.4M | Add +13.8% |
| HON Honeywell International Inc. | 0.12% | 6,317 | $1.3M | Add +8.8% |
| GOOG Alphabet Inc. Class C | 0.11% | 5,059 | $1.2M | Add +5.6% |
| FUN Six Flags Entertainment Corp. | 0.10% | 47,092 | $1.1M | Add +14.6% |
| MSFT Microsoft Corp. | 0.09% | 1,826 | $946K | Add +7.3% |
| META Meta Platforms Inc. Class A | 0.08% | 1,269 | $932K | Add +2.1% |
| IYE iShares U.S. Energy ETF | 0.08% | 19,599 | $931K | Add +13.9% |
| AMZN Amazon.com Inc. | 0.08% | 4,086 | $897K | Add +5.2% |
| TMO Thermo Fisher Scientific Inc. | 0.08% | 1,799 | $873K | New |
| BIO Bio-Rad Laboratories-A | 0.08% | 3,024 | $848K | Add +16.9% |
| GXO Gxo Logistics Inc. | 0.08% | 15,676 | $829K | No change |
| GO Grocery Outlet Holding Corp. | 0.06% | 37,863 | $608K | Reduce -8.7% |
Portfolio Sells Q2 2025 → Q3 2025
Portfolio Buys Q2 2025 → Q3 2025
| VTWO Vanguard Russell 2000 ETF | New | 0.29% | +0.29 |
| TMO Thermo Fisher Scientific Inc. | New | 0.08% | +0.08 |
| PFGC Performance Food Group Co. | Add +17.9% | 0.16% | +0.07 |
| CSGP Costar Group Inc. | Add +11.0% | 0.21% | +0.07 |
| GOOG Alphabet Inc. Class C | Add +5.6% | 0.11% | +0.05 |
| APD Air Products & Chemicals Inc. | Add +12.7% | 0.13% | +0.04 |
| BIO Bio-Rad Laboratories-A | Add +16.9% | 0.08% | +0.03 |
| MIDD Middleby Corp. | Add +13.8% | 0.12% | +0.03 |
| IYE iShares U.S. Energy ETF | Add +13.9% | 0.08% | +0.03 |
| MSFT Microsoft Corp. | Add +7.3% | 0.09% | +0.03 |
| HON Honeywell International Inc. | Add +8.8% | 0.12% | +0.02 |
| DIS The Walt Disney Co. | Add +4.0% | 0.13% | +0.02 |
| AMZN Amazon.com Inc. | Add +5.2% | 0.08% | +0.02 |
| META Meta Platforms Inc. Class A | Add +2.1% | 0.08% | +0.02 |
| FUN Six Flags Entertainment Corp. | Add +14.6% | 0.10% | +0.01 |
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q2 2026 | 2 | $255.0M | CNC, AZTA |
| Q1 2026 | 3 | $984.9M | MASI, AZTA, CNC |
| Q4 2025 | 3 | $840.6M | MASI, AZTA, CNC |
| Q3 2025 | 21 | $1.1B | MASI, CNC, AZTA, IWM, VTWO |
| Q2 2025 | 19 | $1.4B | MASI, CNC, AZTA, IWM, CSGP |
| Q1 2025 | 5 | $1.5B | MASI, CNC, AZTA, IWM, FUN |
| Q4 2024 | 4 | $1.5B | MASI, CNC, AZTA, FUN |
| Q3 2024 | 4 | $1.8B | CNC, MASI, AZTA, FUN |
| Q2 2024 | 3 | $1.6B | CNC, MASI, AZTA |
| Q1 2024 | 3 | $1.9B | CNC, MASI, AZTA |