Politan Capital Management LP
In its 13F for Q4 2025 (holdings as of December 31, 2025, filed February 17, 2026), Politan Capital Management LP reported 3 stock positions worth $840.6 million. Its top holding was Masimo (MASI) at 71.0% of the portfolio, followed by Azenta (AZTA, 18.3%) and Centene (CNC, 10.7%). Compared with Q3 2025, it sold out of 18 and reduced 1. The biggest sale was Centene (CNC, shares −70%).
- Most Recent 13F
- Q2 2026
- Location
- NEW YORK, NY
- CIK
- 0001885245
- Portfolio Value
- $840.6M (Q4 2025)
- SEC Filing
- 0000902664-26-001110 ↗ filed Feb 17, 2026
Holdings Value
Holdings 3 stocks · $840.6M
Portfolio Sells Q3 2025 → Q4 2025
| CNC Centene Corp. | Reduce -70.4% | 10.72% | −13.30 |
| IWM iShares Russell 2000 ETF | Sold out | 0.00% | −0.39 |
| VTWO Vanguard Russell 2000 ETF | Sold out | 0.00% | −0.29 |
| CSGP Costar Group Inc. | Sold out | 0.00% | −0.21 |
| PFGC Performance Food Group Co. | Sold out | 0.00% | −0.16 |
| APD Air Products & Chemicals Inc. | Sold out | 0.00% | −0.13 |
| DIS The Walt Disney Co. | Sold out | 0.00% | −0.13 |
| MIDD Middleby Corp. | Sold out | 0.00% | −0.12 |
| HON Honeywell International Inc. | Sold out | 0.00% | −0.12 |
| GOOG Alphabet Inc. Class C | Sold out | 0.00% | −0.11 |
| FUN Six Flags Entertainment Corp. | Sold out | 0.00% | −0.10 |
| MSFT Microsoft Corp. | Sold out | 0.00% | −0.09 |
| META Meta Platforms Inc. Class A | Sold out | 0.00% | −0.08 |
| IYE iShares U.S. Energy ETF | Sold out | 0.00% | −0.08 |
| AMZN Amazon.com Inc. | Sold out | 0.00% | −0.08 |
| TMO Thermo Fisher Scientific Inc. | Sold out | 0.00% | −0.08 |
| BIO Bio-Rad Laboratories-A | Sold out | 0.00% | −0.08 |
| GXO Gxo Logistics Inc. | Sold out | 0.00% | −0.08 |
| GO Grocery Outlet Holding Corp. | Sold out | 0.00% | −0.06 |
Portfolio Buys Q3 2025 → Q4 2025
| None this quarter. | |||
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q2 2026 | 2 | $255.0M | CNC, AZTA |
| Q1 2026 | 3 | $984.9M | MASI, AZTA, CNC |
| Q4 2025 | 3 | $840.6M | MASI, AZTA, CNC |
| Q3 2025 | 21 | $1.1B | MASI, CNC, AZTA, IWM, VTWO |
| Q2 2025 | 19 | $1.4B | MASI, CNC, AZTA, IWM, CSGP |
| Q1 2025 | 5 | $1.5B | MASI, CNC, AZTA, IWM, FUN |
| Q4 2024 | 4 | $1.5B | MASI, CNC, AZTA, FUN |
| Q3 2024 | 4 | $1.8B | CNC, MASI, AZTA, FUN |
| Q2 2024 | 3 | $1.6B | CNC, MASI, AZTA |
| Q1 2024 | 3 | $1.9B | CNC, MASI, AZTA |