Simplify Asset Management Inc.

In its 13F for Q1 2025 (holdings as of March 31, 2025, filed May 13, 2025), Simplify Asset Management Inc. reported 92 stock positions worth $2.1 billion. Its top holding was iShares Core S&P 500 ETF (IVV) at 31.6% of the portfolio, followed by SS SPDR S&P 500 ETF Trust-US (SPY, 22.8%) and iShares Core U.S. Aggregate (AGG, 14.1%). Compared with Q4 2024, it opened 16 new positions, sold out of 13, added to 40 and reduced 26. The biggest buy was a new position in SS SPDR S&P 500 ETF Trust-US (SPY) and the biggest sale an exit from Simplify Treasury Option (BUCK).

Most Recent 13F
Q2 2026
Location
Las Vegas, NV
CIK
0001846368
Portfolio Value
$2.1B (Q1 2025)
SEC Filing
0001172661-25-001739 ↗ filed May 13, 2025

Holdings Value

0$2.0B$4.0B$6.0B$8.0B Q1 2024: $1.0B Q1 2024 Q2 2024: $1.1B Q2 2024 Q3 2024: $1.5B Q3 2024 Q4 2024: $1.4B Q4 2024 Q1 2025: $2.1B $2.1B Q1 2025 Q2 2025: $1.7B Q2 2025 Q3 2025: $4.9B Q3 2025 Q4 2025: $6.1B Q4 2025 Q1 2026: $6.5B Q1 2026 Q2 2026: $7.1B Q2 2026

Holdings 92 stocks · $2.1B
IVV iShares Core S&P 500 ETF 31.56% 1,203,395 $676.2M Add +21.9%
SPY SS SPDR S&P 500 ETF Trust-US 22.77% 872,087 $487.8M New
AGG iShares Core U.S. Aggregate 14.07% 3,046,844 $301.4M Add +31.4%
AGGH Simplify Aggregate Bond ETF 5.13% 5,193,254 $109.8M No change
QIS Simplify Multi-Qis Alt ETF 4.38% 4,041,360 $93.8M Add +2390.2%
SPUC Simplify US Equity Income Et 4.16% 2,334,812 $89.1M New
NMB Simplify National Muni BND 3.29% 3,121,709 $70.6M Reduce -0.2%
TYA Simplify Intermediate Term 2.44% 3,948,182 $52.2M Add +2.7%
CDX Simplify High Yield ETF 1.39% 1,299,393 $29.8M No change
PAGP Plains GP Holdings LP 1.27% 1,272,360 $27.2M No change
FOXY Simplify Currency Strtgy ETF 0.59% 463,739 $12.6M New
LLY Eli Lilly & Co. 0.55% 14,290 $11.8M Add +66.0%
ARQT Arcutis Biotherapeutics Inc. 0.48% 660,557 $10.3M Reduce -11.0%
DHR Danaher Corp. 0.40% 41,844 $8.6M Add +2965.5%
UNH Unitedhealth Group Inc. 0.33% 13,427 $7.0M Add +11.4%
CAH Cardinal Health Inc. 0.33% 51,212 $7.0M Add +739.4%
CI The Cigna Group 0.33% 21,359 $7.0M Add +70.2%
JNJ Johnson & Johnson 0.33% 42,217 $7.0M Reduce -1.9%
ADMA Adma Biologics Inc. 0.32% 343,609 $6.8M Reduce -10.8%
ISRG Intuitive Surgical Inc. 0.28% 12,223 $6.1M Reduce -9.4%
AKRO Akero Therapeutics Inc. 0.28% 145,609 $5.9M Reduce -45.0%
MDGL Madrigal Pharmaceuticals Inc. 0.25% 16,302 $5.4M Reduce -30.0%
TMO Thermo Fisher Scientific Inc. 0.21% 9,070 $4.5M Add +0.5%
PHAT Phathom Pharmaceuticals Inc. 0.20% 681,935 $4.3M Add +17.2%
ABBV Abbvie Inc. 0.20% 20,402 $4.3M New
RNAM Avidity Biosciences Inc. 0.17% 125,000 $3.7M No change
PCT Purecycle Technologies Inc. 0.16% 510,086 $3.5M Reduce -56.1%
DGX Quest Diagnostics Inc. 0.16% 20,671 $3.5M New
TSLA Tesla Inc. 0.16% 12,904 $3.3M Add +3.0%
PCRX Pacira Biosciences Inc. 0.16% 134,042 $3.3M Add +255.2%
AGNC AGNC Investment Corp. 0.14% 321,550 $3.1M Add +124.0%
PM Philip Morris International 0.14% 18,480 $2.9M New
HODL Vaneck Bitcoin ETF 0.13% 121,480 $2.8M New
AZN Astrazeneca PLC-Spons ADR 0.12% 35,990 $2.6M New
ALHC Alignment Healthcare Inc. 0.12% 133,466 $2.5M Add +0.5%
RMD Resmed Inc. 0.12% 11,101 $2.5M Reduce -63.2%
IJR iShares Core S&P Small-Cap E 0.11% 23,346 $2.4M Add +21.1%
GILD Gilead Sciences Inc. 0.11% 21,272 $2.4M Reduce -53.9%
TSLL Dirx DLY Tsla Bul 2X ETF-Aui 0.11% 245,408 $2.3M Add +34.8%
SNY Sanofi-ADR 0.11% 40,597 $2.3M Add +0.5%
NBIX Neurocrine Biosciences Inc. 0.10% 20,274 $2.2M New
APLT Applied Therapeutics Inc. 0.10% 4,487,505 $2.2M Add +59.3%
RITM Rithm Capital Corp. 0.10% 190,780 $2.2M Add +8.5%
NLY Annaly Capital Management Inc. 0.10% 105,190 $2.1M Add +31.0%
HARD Simplify Commodities STR K-1 0.10% 66,957 $2.1M New
RFIX Simplify Bond Bull ETF 0.09% 37,400 $2.0M New
CTA Simplify Managed Futures St 0.09% 66,957 $2.0M Reduce -52.3%
ABEO Abeona Therapeutics Inc. 0.09% 408,584 $1.9M No change
SCY Simplify US Smllcap Plus Inc. 0.09% 95,000 $1.9M New
SNDX Syndax Pharmaceuticals Inc. 0.08% 147,785 $1.8M Add +0.1%
TFX Teleflex Inc. 0.08% 12,826 $1.8M Add +0.7%
REGN Regeneron Pharmaceuticals 0.08% 2,758 $1.7M Reduce -55.9%
RVTY Revvity Inc. 0.08% 16,003 $1.7M Add +0.5%
INSM Insmed Inc. 0.07% 20,630 $1.6M Add +0.5%
DCTH Delcath Systems Inc. 0.07% 117,000 $1.5M Add +588.2%
TCRX Tscan Therapeutics Inc. 0.07% 1,046,916 $1.4M No change
ABT Abbott Laboratories 0.07% 10,858 $1.4M Reduce -50.8%
WUSA Simplify Wo US Eq 150/50 ETF 0.06% 57,200 $1.4M Reduce -4.3%
DXCM Dexcom Inc. 0.06% 18,809 $1.3M Reduce -82.2%
PMT Pennymac Mortgage Investment 0.06% 86,100 $1.3M Add +49.5%
BNTC Benitec Biopharma Inc. 0.05% 76,735 $998K Add +0.5%
ARGX Argenx SE - ADR 0.04% 1,619 $958K Add +0.5%
CIM Chimera Investment Corp. 0.04% 70,700 $907K Add +175.1%
ZVRA Zevra Therapeutics Inc. 0.04% 120,000 $899K No change
SPQ Simplify US Equity Plus Qis 0.04% 32,131 $795K Reduce -4.3%
NXTI Simplify Next Intg C Idx ETF 0.03% 25,825 $714K Reduce -4.3%
EW Edwards Lifesciences Corp. 0.03% 9,799 $710K Reduce -87.9%
LGND Ligand Pharmaceuticals 0.03% 6,616 $696K New
MIST Milestone Pharmaceuticals Inc. 0.03% 850,000 $680K New
ESTA Establishment Labs Holdings 0.03% 16,222 $662K Reduce -74.8%
NXTV Simplify Next Int Va Idx ETF 0.03% 25,825 $659K Reduce -4.3%
ARR Armour Residential REIT Inc. 0.03% 37,500 $641K Add +36.4%
CVS CVS Health Corp. 0.03% 9,105 $617K Reduce -0.1%
RARE Ultragenyx Pharmaceutical Inc. 0.03% 16,900 $612K Add +0.5%
COO The Cooper Cos Inc. 0.03% 6,908 $583K Reduce -56.3%
ACHV Achieve Life Sciences Inc. 0.03% 217,845 $582K No change
VRTX Vertex Pharmaceuticals Inc. 0.03% 1,195 $579K Reduce -74.5%
AGL Agilon Health Inc. 0.02% 111,096 $481K Add +0.5%
EYPT Eyepoint Inc. 0.02% 88,155 $478K New
SYK Stryker Corp. 0.02% 1,212 $451K Add +0.5%
TGTX TG Therapeutics Inc. 0.02% 11,288 $445K Add +0.5%
ATHIRA PHARMA INC 0.02% 1,492,792 $425K No change
TWO Two Harbors Investment Corp. filed as TWO HBRS INVT CORP 0.02% 31,000 $414K Add +181.8%
LIVN Livanova PLC 0.02% 9,446 $371K Add +0.5%
CYPH Cypherpunk Technologies Inc. filed as LEAP THERAPEUTICS INC 0.01% 950,973 $290K Add +0.5%
ZBH Zimmer Biomet Holdings Inc. 0.01% 2,326 $263K Add +0.8%
MMM 3M Co. 0.01% 1,770 $260K Reduce -93.2%
SRPT Sarepta Therapeutics Inc. 0.01% 4,054 $259K Reduce -87.6%
FULC Fulcrum Therapeutics Inc. 0.01% 81,134 $234K Add +0.5%
CHWY Chewy Inc. Class A 0.01% 7,092 $231K Reduce -90.3%
CMPX Compass Therapeutics Inc. 0.01% 120,000 $228K New
QVCG QVC Group Inc. 0.01% 600,000 $121K No change

Options reported separately and not counted above: GLD puts ($408.5M), MSTR puts ($118.8M).

Portfolio Sells Q4 2024 → Q1 2025
BUCK Simplify Treasury Option Inc. Sold out 0.00% −7.59
NMB Simplify National Muni BND Reduce -0.2% 3.29% −1.98
MINT PIMCO Enhanced Short Maturit Sold out 0.00% −1.76
PCT Purecycle Technologies Inc. Reduce -56.1% 0.16% −0.66
DXCM Dexcom Inc. Reduce -82.2% 0.06% −0.51
EW Edwards Lifesciences Corp. Reduce -87.9% 0.03% −0.38
RMD Resmed Inc. Reduce -63.2% 0.12% −0.36
BTC Grayscale Bitcoin Mini ETF Sold out 0.00% −0.29
SRPT Sarepta Therapeutics Inc. Reduce -87.6% 0.01% −0.27
TUA Sim St Treas Fut Strat ETF Sold out 0.00% −0.25
MDGL Madrigal Pharmaceuticals Inc. Reduce -30.0% 0.25% −0.25
ARDX Ardelyx Inc. Sold out 0.00% −0.24
AKRO Akero Therapeutics Inc. Reduce -45.0% 0.28% −0.24
ARQT Arcutis Biotherapeutics Inc. Reduce -11.0% 0.48% −0.24
PRAX Praxis Precision Medicines I Sold out 0.00% −0.23
REGN Regeneron Pharmaceuticals Reduce -55.9% 0.08% −0.23
MMM 3M Co. Reduce -93.2% 0.01% −0.22
ISRG Intuitive Surgical Inc. Reduce -9.4% 0.28% −0.21
GILD Gilead Sciences Inc. Reduce -53.9% 0.11% −0.19
CTA Simplify Managed Futures St Reduce -52.3% 0.09% −0.18
ESTA Establishment Labs Holdings Reduce -74.8% 0.03% −0.18
CHWY Chewy Inc. Class A Reduce -90.3% 0.01% −0.16
ADMA Adma Biologics Inc. Reduce -10.8% 0.32% −0.14
ITCI Intra-Cellular Therapies Inc. Sold out 0.00% −0.12
ABT Abbott Laboratories Reduce -50.8% 0.07% −0.11
JNJ Johnson & Johnson Reduce -1.9% 0.33% −0.11
VRTX Vertex Pharmaceuticals Inc. Reduce -74.5% 0.03% −0.10
KYMR Kymera Therapeutics Inc. Sold out 0.00% −0.09
COO The Cooper Cos Inc. Reduce -56.3% 0.03% −0.07
TSLR Granitesh 2X LNG Tsla ETF Sold out 0.00% −0.06
KURA Kura Oncology Inc. Sold out 0.00% −0.05
WUSA Simplify Wo US Eq 150/50 ETF Reduce -4.3% 0.06% −0.04
JSPR Jasper Therapeutics Inc. Sold out 0.00% −0.03
SPQ Simplify US Equity Plus Qis Reduce -4.3% 0.04% −0.03
NXTI Simplify Next Intg C Idx ETF Reduce -4.3% 0.03% −0.02
CEE Central and Eastern Europe F Sold out 0.00% −0.02
NXTV Simplify Next Int Va Idx ETF Reduce -4.3% 0.03% −0.02
CMPS Compass Pathways PLC Sold out 0.00% −0.00
CVS CVS Health Corp. Reduce -0.1% 0.03% +0.00

Portfolio Buys Q4 2024 → Q1 2025
SPY SS SPDR S&P 500 ETF Trust-US New 22.77% +22.77
SPUC Simplify US Equity Income Et New 4.16% +4.16
QIS Simplify Multi-Qis Alt ETF Add +2390.2% 4.38% +4.10
FOXY Simplify Currency Strtgy ETF New 0.59% +0.59
DHR Danaher Corp. Add +2965.5% 0.40% +0.38
CAH Cardinal Health Inc. Add +739.4% 0.33% +0.28
ABBV Abbvie Inc. New 0.20% +0.20
DGX Quest Diagnostics Inc. New 0.16% +0.16
PM Philip Morris International New 0.14% +0.14
HODL Vaneck Bitcoin ETF New 0.13% +0.13
AZN Astrazeneca PLC-Spons ADR New 0.12% +0.12
PCRX Pacira Biosciences Inc. Add +255.2% 0.16% +0.11
NBIX Neurocrine Biosciences Inc. New 0.10% +0.10
HARD Simplify Commodities STR K-1 New 0.10% +0.10
RFIX Simplify Bond Bull ETF New 0.09% +0.09
LLY Eli Lilly & Co. Add +66.0% 0.55% +0.09
CI The Cigna Group Add +70.2% 0.33% +0.09
SCY Simplify US Smllcap Plus Inc. New 0.09% +0.09
DCTH Delcath Systems Inc. Add +588.2% 0.07% +0.06
AGNC AGNC Investment Corp. Add +124.0% 0.14% +0.05
LGND Ligand Pharmaceuticals New 0.03% +0.03
MIST Milestone Pharmaceuticals Inc. New 0.03% +0.03
EYPT Eyepoint Inc. New 0.02% +0.02
CIM Chimera Investment Corp. Add +175.1% 0.04% +0.02
ALHC Alignment Healthcare Inc. Add +0.5% 0.12% +0.01
CMPX Compass Therapeutics Inc. New 0.01% +0.01
TWO Two Harbors Investment Corp. Add +181.8% 0.02% +0.01
PMT Pennymac Mortgage Investment Add +49.5% 0.06% +0.01
AGL Agilon Health Inc. Add +0.5% 0.02% +0.01
NLY Annaly Capital Management Inc. Add +31.0% 0.10% −0.00
TGTX TG Therapeutics Inc. Add +0.5% 0.02% −0.00
ZBH Zimmer Biomet Holdings Inc. Add +0.8% 0.01% −0.00
ARR Armour Residential REIT Inc. Add +36.4% 0.03% −0.01
SYK Stryker Corp. Add +0.5% 0.02% −0.01
LIVN Livanova PLC Add +0.5% 0.02% −0.01
FULC Fulcrum Therapeutics Inc. Add +0.5% 0.01% −0.02
BNTC Benitec Biopharma Inc. Add +0.5% 0.05% −0.02
RARE Ultragenyx Pharmaceutical Inc. Add +0.5% 0.03% −0.02
ARGX Argenx SE - ADR Add +0.5% 0.04% −0.02
INSM Insmed Inc. Add +0.5% 0.07% −0.03
RITM Rithm Capital Corp. Add +8.5% 0.10% −0.03
SNY Sanofi-ADR Add +0.5% 0.11% −0.03
IJR iShares Core S&P Small-Cap E Add +21.1% 0.11% −0.04
RVTY Revvity Inc. Add +0.5% 0.08% −0.04
SNDX Syndax Pharmaceuticals Inc. Add +0.1% 0.08% −0.05
APLT Applied Therapeutics Inc. Add +59.3% 0.10% −0.07
TFX Teleflex Inc. Add +0.7% 0.08% −0.07
UNH Unitedhealth Group Inc. Add +11.4% 0.33% −0.10
TMO Thermo Fisher Scientific Inc. Add +0.5% 0.21% −0.12
PHAT Phathom Pharmaceuticals Inc. Add +17.2% 0.20% −0.13

Options Activity Q4 2024 → Q1 2025
GLD SPDR Gold Shares put Reduce -22.4% 1,420,600 $408.5M
MSTR Strategy Inc. put Add +23.2% 391,500 $118.8M
IBIT iShares Bitcoin Trust ETF call Sold out 750,000 $41.5Mbefore exit

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 136$7.1BSBIL, IVV, AGG, TUA, SPUC
Q1 2026 142$6.5BSBIL, IVV, AGG, TUA, SPUC
Q4 2025 140$6.1BSBIL, IVV, AGG, SPUC, QIS
Q3 2025 127$4.9BSBIL, IVV, AGG, QIS, SPUC
Q2 2025 87$1.7BIVV, AGG, AGGH, QIS, SPUC
Q1 2025 92$2.1BIVV, SPY, AGG, AGGH, QIS
Q4 2024 89$1.4BIVV, AGG, BUCK, AGGH, NMB
Q3 2024Amended 101$1.5BIVV, AGG, AGGH, BUCK, NMB
Q2 2024 100$1.1BIVV, AGG, AGGH, CDX, BUCK
Q1 2024 96$1.0BIVV, AGGH, BUCK, AGG, PAGP