Applied TherapeuticsAPLT
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 52 institutions reported holding Applied Therapeutics Inc. (APLT) in their 13F filings, down 18 from Q3 2025. 9 opened new positions and 25 sold out. The largest holders were T. Rowe Price Investment Management, Inc. ($2.2M), Vanguard Group Inc. ($635K) and Knoll Capital Management, LLC ($605K). 5 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Applied Therapeutics Inc.
- CUSIP
- 03828A101
- Latest filing quarter
- Q4 2025
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 9 | $1.0M |
| Exits | 25 | $24.1M |
All 13F filers, Q3 2025 → Q4 2025: 13,017,827 shares bought and 48,845,338 shares sold, net −35,827,511 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 52 holders
| T. Rowe Price Investment Management, Inc. | 0.00% | Add +1.6% | 21,747,844 | $2.2M |
| Vanguard Group Inc. | 0.00% | Add +24.5% | 6,353,018 | $635K |
| Knoll Capital Management, LLC | 0.28% | Reduce -22.4% | 6,050,000 | $605K |
| Deltec Asset Management LLC | 0.06% | New | 3,847,449 | $385K |
| BlackRock, Inc. | 0.00% | Reduce -15.4% | 3,251,462 | $325K |
| Pathstone Holdings, LLC | 0.00% | No change | 2,643,540 | $305K |
| Renaissance Technologies | 0.00% | New | 2,706,156 | $271K |
| Jane Street Group, LLC | 0.00% | New | 2,087,404 | $209K |
| Geode Capital Management, LLC | 0.00% | Add +16.8% | 1,492,903 | $149K |
| Adage Capital Partners Gp, L.L.C. | 0.00% | Reduce -45.2% | 1,211,629 | $121K |
| Millennium Management | 0.00% | Reduce -44.9% | 1,051,846 | $105K |
| UBS Group AG | 0.00% | Reduce -62.3% | 718,924 | $72K |
| Deutsche Bank AG | 0.00% | No change | 622,226 | $62K |
| Graham Capital Management, L.P. | 0.00% | New | 572,759 | $57K |
| State Street Corp. | 0.00% | Add +7.7% | 558,178 | $56K |
| Virtu Financial LLC | 0.00% | Add +872.8% | 496,288 | $50K |
| Lynx1 Capital Management LP | 0.01% | New | 410,500 | $41K |
| Marshall Wace, LLP | 0.00% | Reduce -86.7% | 337,389 | $34K |
| Hennion & Walsh Asset Management, Inc. | 0.00% | Add +15.7% | 327,137 | $33K |
| Equitec Proprietary Markets, LLC | 0.15% | New | 300,600 | $30K |
| Bank of New York Mellon Corp | 0.00% | Add +219.3% | 253,575 | $25K |
| Northern Trust Corp. | 0.00% | Add +41.1% | 245,144 | $25K |
| Rockefeller Capital Management L.P. | 0.00% | Reduce -38.3% | 241,897 | $24K |
| GTS Securities LLC | 0.00% | New | 200,009 | $20K |
| Morgan Stanley | 0.00% | Reduce -75.0% | 178,474 | $18K |
| CreativeOne Wealth, LLC | 0.00% | Add +70.0% | 169,974 | $17K |
| Citigroup Inc. | 0.00% | Add +2289.3% | 163,449 | $16K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -5.8% | 146,219 | $15K |
| Roble, Belko & Company, Inc | 0.00% | Add +112.6% | 65,571 | $7K |
| Tudor Investment Corporation | 0.00% | No change | 57,454 | $6K |
| Susquehanna International Group, LLP | 0.00% | Reduce -89.0% | 52,692 | $5K |
| Sphera Funds Management LTD. | 0.00% | No change | 50,000 | $5K |
| Group One Trading LLC | 0.00% | Reduce -35.3% | 48,675 | $5K |
| SG Americas Securities, LLC | 0.00% | Add +154.5% | 41,748 | $4K |
| Adams Wealth Management | 0.00% | No change | 38,637 | $4K |
| CacheTech Inc. | 0.00% | No change | 38,637 | $4K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -42.7% | 19,675 | $2K |
| Cresset Asset Management, LLC | 0.00% | No change | 17,091 | $2K |
| Point72 Asset Management | 0.00% | New | 17,020 | $2K |
| AQR Capital Management | 0.00% | Reduce -87.8% | 13,413 | $1K |
| JPMorgan Chase & Co. | 0.00% | Add +58.1% | 12,064 | $1K |
| Perennial Investment Advisors, LLC | 0.00% | No change | 11,600 | $1K |
| AlphaQuest LLC | 0.00% | No change | 4,661 | $466 |
| Bank of America Corp. | 0.00% | Reduce -73.4% | 3,109 | $311 |
| BNP Paribas Financial Markets | 0.00% | Reduce -14.4% | 2,974 | $297 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -4.3% | 788 | $79 |
| Rhumbline Advisers | 0.00% | No change | 544 | $54 |
| Optiver Holding B.V. | 0.00% | New | 427 | $43 |
| FMR LLC | 0.00% | Reduce -99.0% | 184 | $18 |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 84 | $8 |
| Barclays PLC | 0.00% | Reduce -100.0% | 1 | $0 |
| Royal Bank of Canada | 0.00% | Reduce -99.6% | 852 | $0 |
"% of holder's portfolio" is APLT's weight in each manager's 13F, not the share of Applied Therapeutics Inc. the manager owns.