TRV GP Vi, LLC

In its 13F for Q2 2026 (holdings as of June 30, 2026, filed August 10, 2026), TRV GP Vi, LLC reported 4 stock positions worth $232.3 million. Its top holding was Septerna (SEPN) at 60.7% of the portfolio, followed by Seaport Therapeutics (SPTX, 19.3%) and Rapport Therapeutics (RAPP, 17.4%). Compared with Q1 2026, it opened 1 new position. The biggest buy was a new position in Seaport Therapeutics (SPTX).

Most Recent 13F
Q2 2026
Location
Boston, MA
CIK
0001990716
Portfolio Value
$232.3M (Q2 2026)
SEC Filing
0001193125-26-340715 ↗ filed Aug 10, 2026

Holdings Value

0$50.0M$100.0M$150.0M$200.0M$250.0M Q4 2024: $116.9M Q4 2024 Q1 2025: $42.0M Q1 2025 Q2 2025: $64.2M Q2 2025 Q3 2025: $109.6M Q3 2025 Q4 2025: $148.5M Q4 2025 Q1 2026: $135.6M Q1 2026 Q2 2026: $232.3M $232.3M Q2 2026

Holdings 4 stocks · $232.3M
SEPN Septerna Inc. 60.72% 4,211,659 $141.0M No change
SPTX Seaport Therapeutics Inc. 19.27% 2,061,222 $44.8M New
RAPP Rapport Therapeutics Inc. 17.39% 969,218 $40.4M No change
TNGX Tango Therapeutics Inc. 2.61% 194,174 $6.1M No change

Portfolio Sells Q1 2026 → Q2 2026
None this quarter.

Portfolio Buys Q1 2026 → Q2 2026
SPTX Seaport Therapeutics Inc. New 19.27% +19.27

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 4$232.3MSEPN, SPTX, RAPP, TNGX
Q1 2026 3$135.6MSEPN, RAPP, TNGX
Q4 2025 3$148.5MSEPN, RAPP, TNGX
Q3 2025 3$109.6MSEPN, RAPP, TNGX
Q2 2025 4$64.2MSEPN, RAPP, CRGX, TNGX
Q1 2025 4$42.0MSEPN, RAPP, CRGX, TNGX
Q4 2024 4$116.9MSEPN, CRGX, RAPP, TNGX