TRV GP Vi, LLC

In its 13F for Q4 2025 (holdings as of December 31, 2025, filed February 13, 2026), TRV GP Vi, LLC reported 3 stock positions worth $148.5 million. Its top holding was Septerna (SEPN) at 79.0% of the portfolio, followed by Rapport Therapeutics (RAPP, 19.8%) and Tango Therapeutics (TNGX, 1.2%). Its holdings were unchanged from Q3 2025.

Most Recent 13F
Q2 2026
Location
Boston, MA
CIK
0001990716
Portfolio Value
$148.5M (Q4 2025)
SEC Filing
0001193125-26-051801 ↗ filed Feb 13, 2026

Holdings Value

0$50.0M$100.0M$150.0M$200.0M$250.0M Q4 2024: $116.9M Q4 2024 Q1 2025: $42.0M Q1 2025 Q2 2025: $64.2M Q2 2025 Q3 2025: $109.6M Q3 2025 Q4 2025: $148.5M $148.5M Q4 2025 Q1 2026: $135.6M Q1 2026 Q2 2026: $232.3M Q2 2026

Holdings 3 stocks · $148.5M
SEPN Septerna Inc. 79.05% 4,211,659 $117.4M No change
RAPP Rapport Therapeutics Inc. 19.80% 969,218 $29.4M No change
TNGX Tango Therapeutics Inc. 1.16% 194,174 $1.7M No change

Portfolio Sells Q3 2025 → Q4 2025
None this quarter.

Portfolio Buys Q3 2025 → Q4 2025
None this quarter.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 4$232.3MSEPN, SPTX, RAPP, TNGX
Q1 2026 3$135.6MSEPN, RAPP, TNGX
Q4 2025 3$148.5MSEPN, RAPP, TNGX
Q3 2025 3$109.6MSEPN, RAPP, TNGX
Q2 2025 4$64.2MSEPN, RAPP, CRGX, TNGX
Q1 2025 4$42.0MSEPN, RAPP, CRGX, TNGX
Q4 2024 4$116.9MSEPN, CRGX, RAPP, TNGX