Adagio Medical HoldingsADGM

13F holders, Q4 2025 (December 31)
21holders +6
11new positions
5sold out
$1.04avg. 13F price*

At the end of Q4 2025, 21 institutions reported holding Adagio Medical Holdings Inc. (ADGM) in their 13F filings, up 6 from Q3 2025. 11 opened new positions and 5 sold out. The largest holders were Perceptive Advisors LLC ($10.3M), Sio Capital Management, LLC ($1.3M) and Adage Capital Partners Gp, L.L.C. ($1.3M).

Company
Adagio Medical Holdings Inc.
CUSIP
00534B100
Latest filing quarter
Q2 2026

History

Number of 13F holders

0510152025 Q3 2024: 12Q3 2024Q4 2024: 15Q4 2024Q1 2025: 15Q1 2025Q2 2025: 12Q2 2025Q3 2025: 15Q3 2025Q4 2025: 21Q4 2025Q1 2026: 23Q1 2026Q2 2026: 24Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions11$5.2M
Exits5$459K

All 13F filers, Q3 2025 → Q4 2025: 5,252,399 shares bought and 337,416 shares sold, net +4,914,983 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 21 holders

Perceptive Advisors LLC 0.19% No change 9,876,576 $10.3M
Sio Capital Management, LLC 0.22% New 1,288,461 $1.3M
Adage Capital Partners Gp, L.L.C. 0.00% Add +18.9% 1,258,501 $1.3M
Alyeska Investment Group, L.P. 0.00% New 1,159,615 $1.2M
ADAR1 Capital Management, LLC 0.09% New 1,159,614 $1.2M
Silverarc Capital Management, LLC 0.08% New 515,384 $536K
Armistice Capital, LLC 0.01% New 478,000 $497K
Hudson Bay Capital Management LP 0.00% New 296,369 $308K
Shaolin Capital Management LLC 0.02% Reduce -4.9% 171,170 $178K
Affinity Asset Advisors, LLC 0.01% No change 80,000 $83K
Vanguard Group Inc. 0.00% Add +140.2% 79,451 $83K
Geode Capital Management, LLC 0.00% Add +88.6% 68,342 $71K
Toronto Dominion Bank 0.00% No change 25,000 $26K
Northern Trust Corp. 0.00% New 21,598 $22K
Opaleye Management Inc. 0.00% Reduce -83.3% 18,444 $19K
HRT Financial LP 0.00% New 18,618 $19K
XTX Topco Ltd 0.00% New 18,103 $19K
Bank of America Corp. 0.00% Add +39534.5% 11,494 $12K
Tower Research Capital LLC (TRC) 0.00% Add +290.9% 8,146 $8K
Crewe Advisors LLC 0.00% New 500 $520
Morgan Stanley 0.00% New 137 $142

"% of holder's portfolio" is ADGM's weight in each manager's 13F, not the share of Adagio Medical Holdings Inc. the manager owns.