ADAR1 Capital Management, LLC

In its 13F for Q2 2026 (holdings as of June 30, 2026, filed August 14, 2026), ADAR1 Capital Management, LLC reported 260 stock positions worth $2.1 billion. Its top holding was Abivax SA-ADR (ABVX) at 11.4% of the portfolio, followed by Protagonist Therapeutics (PTGX, 5.6%) and Roivant Sciences (ROIV, 5.3%). Compared with Q1 2026, it opened 40 new positions, sold out of 70, added to 98 and reduced 64. The biggest buy was Abivax SA-ADR (ABVX, shares +29%) and the biggest sale an exit from Terns Pharmaceuticals (TERN).

Most Recent 13F
Q2 2026
Location
AUSTIN, TX
CIK
0001940272
Portfolio Value
$2.1B (Q2 2026)
SEC Filing
0001940272-26-000015 ↗ filed Aug 14, 2026

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q1 2024: $366.2M Q1 2024 Q2 2024: $496.6M Q2 2024 Q3 2024: $596.5M Q3 2024 Q4 2024: $469.3M Q4 2024 Q1 2025: $505.1M Q1 2025 Q2 2025: $609.1M Q2 2025 Q3 2025: $1.0B Q3 2025 Q4 2025: $1.3B Q4 2025 Q1 2026: $1.6B Q1 2026 Q2 2026: $2.1B $2.1B Q2 2026

Holdings 260 stocks · $2.1B

ABVX Abivax SA-ADR 11.39% 1,804,703 $240.5M Add +29.5%
PTGX Protagonist Therapeutics Inc. 5.58% 960,863 $117.8M Reduce -3.4%
ROIV Roivant Sciences Ltd. 5.29% 3,157,008 $111.7M Reduce -3.9%
SPY SS SPDR S&P 500 ETF Trust-US 4.56% 129,087 $96.4M Add +70.0%
IMVT Immunovant Inc. 4.25% 2,330,716 $89.8M Reduce -13.0%
ZLAB Zai Lab Ltd.-ADR 3.03% 3,369,034 $64.0M Add +136.4%
AGIO Agios Pharmaceuticals Inc. 2.26% 1,288,053 $47.8M Add +815.6%
CRNX Crinetics Pharmaceuticals Inc. 2.17% 1,222,080 $45.7M Add +7.3%
BOXX Alpha Architect 1-3 MNTH Box 1.87% 337,125 $39.5M No change
CYTK Cytokinetics Inc. 1.85% 457,907 $39.0M Reduce -27.6%
SEPN Septerna Inc. 1.49% 940,747 $31.5M Reduce -13.7%
AVR Anteris Technologies Global 1.47% 3,145,096 $31.0M Reduce -17.0%
EDIT Editas Medicine Inc. 1.36% 8,889,000 $28.8M New
DNLI Denali Therapeutics Inc. 1.25% 1,029,080 $26.5M Reduce -45.0%
SYRE Spyre Therapeutics Inc. 1.19% 283,982 $25.2M Reduce -16.1%
VIR Vir Biotechnology Inc. 1.19% 2,456,677 $25.0M Reduce -10.5%
PRAX Praxis Precision Medicines I 1.18% 74,253 $24.9M Add +4850.2%
INSM Insmed Inc. 1.15% 228,520 $24.4M Add +545.7%
CLDX Celldex Therapeutics Inc. 1.09% 619,542 $23.1M Add +44.8%
VKTX Viking Therapeutics Inc. 1.06% 574,038 $22.4M Add +152.1%
TSHA Taysha Gene Therapies Inc. 0.98% 3,040,466 $20.7M Add +2.0%
MNPR Monopar Therapeutics Inc. 0.95% 217,595 $20.1M Reduce -17.7%
OVID Ovid Therapeutics Inc. 0.94% 7,417,479 $20.0M Add +63.2%
ELVN Enliven Therapeutics Inc. 0.93% 387,718 $19.7M Add +17.6%
ENTA Enanta Pharmaceuticals Inc. 0.93% 1,344,510 $19.6M Add +2518.0%
NKTR Nektar Therapeutics 0.81% 244,184 $17.0M Add +51.4%
INSP Inspire Medical Systems Inc. 0.79% 374,617 $16.7M Reduce -7.5%
RVMD Revolution Medicines Inc. 0.78% 87,509 $16.4M Reduce -34.6%
ESTA Establishment Labs Holdings 0.75% 185,619 $15.9M Reduce -13.1%
PRTA Prothena Corp. PLC 0.72% 1,554,535 $15.2M Reduce -1.7%
RYTM Rhythm Pharmaceuticals Inc. 0.72% 136,158 $15.1M Reduce -35.6%
IKT Inhibikase Therapeutics Inc. 0.71% 7,387,205 $15.0M Add +11.8%
QURE Uniqure NV 0.71% 324,672 $15.0M Add +326.1%
RLYB Rallybio Corp. 0.70% 926,352 $14.8M Add +4411.1%
REGN Regeneron Pharmaceuticals 0.66% 22,208 $13.8M Add +82.7%
IVA Inventiva SA - ADR 0.65% 3,606,656 $13.6M Add +65.9%
STRO Sutro Biopharma Inc. 0.64% 404,014 $13.4M Reduce -23.0%
IONS Ionis Pharmaceuticals Inc. 0.62% 166,286 $13.2M Add +3.7%
BBIO Bridgebio Pharma Inc. 0.62% 176,689 $13.2M Add +87.4%
SRPT Sarepta Therapeutics Inc. 0.62% 730,649 $13.1M Add +178.8%
CTMX Cytomx Therapeutics Inc. 0.60% 3,365,118 $12.6M Reduce -1.3%
VOR Vor Biopharma Inc. 0.59% 680,626 $12.5M New
BIL SS SPDR BB 1-3M T-Bill ETF 0.59% 135,585 $12.4M No change
EQ Equillium Inc. 0.57% 3,758,569 $12.0M Add +0.9%
ANL Adlai Nortye Group Ltd. 0.55% 1,017,805 $11.7M Add +763.2%
CLYM Climb Bio Inc. 0.51% 822,649 $10.7M Add +37.6%
HLXC Helix Acquisition Corp. Class A 0.50% 1,000,000 $10.6M No change
ZURA Zura Bio Ltd. 0.49% 1,759,295 $10.4M Add +179.1%
OKUR Onkure Therapeutics Inc. Class A 0.48% 2,238,684 $10.2M Reduce -8.1%
MAZE Maze Therapeutics Inc. 0.48% 339,276 $10.1M Add +577.3%
XENE Xenon Pharmaceuticals Inc. 0.48% 166,550 $10.1M Reduce -27.2%
TEVA Teva Pharmaceutical-SP ADR 0.45% 277,848 $9.4M Add +3.5%
URGN Urogen Pharma Ltd. 0.44% 252,395 $9.3M Reduce -36.2%
FTH Faeth Therapeutics Inc. 0.43% 361,010 $9.0M New
AMLX Amylyx Pharmaceuticals Inc. 0.42% 494,378 $8.9M Reduce -50.6%
DBVT DBV Technologies SA-Spon ADR 0.41% 528,295 $8.7M Reduce -47.8%
SVRA Savara Inc. 0.41% 1,403,409 $8.6M Reduce -4.2%
PCVX Vaxcyte Inc. 0.40% 146,034 $8.5M Reduce -43.6%
CGON CG Oncology Inc. 0.40% 118,664 $8.4M Reduce -36.1%
MLYS Mineralys Therapeutics Inc. 0.38% 298,886 $8.1M Add +93.2%
ASND Ascendis Pharma A/S 0.36% 28,604 $7.6M Add +14.3%
AMAN Amanat Acquisition Corp. Class A 0.36% 750,000 $7.6M New
NRIX Nurix Therapeutics Inc. 0.36% 313,236 $7.6M Add +458.6%
BHVN Biohaven Ltd. 0.35% 501,687 $7.5M Add +1020.4%
PRME Prime Medicine Inc. 0.35% 1,997,552 $7.4M Add +1.2%
FRNM Freenome Inc. filed as PERCEPTIVE CAP SOLUTIONS COR 0.35% 674,695 $7.3M Add +35.0%
IRD Opus Genetics Inc. 0.35% 1,783,781 $7.3M Reduce -3.5%
LXEO Lexeo Therapeutics Inc. 0.35% 1,565,950 $7.3M Add +6.7%
DMRA Damora Therapeutics Inc. 0.34% 280,000 $7.3M Add +0.4%
REPL Replimune Group Inc. 0.34% 655,784 $7.3M Reduce -58.6%
LONA Leonabio Inc. 0.34% 777,100 $7.1M Add +6.8%
KRRO Korro Bio Inc. 0.34% 540,054 $7.1M No change
RACC Research Alliance Corp. Class A 0.33% 650,000 $7.0M New
IFRX Inflarx NV 0.32% 3,000,000 $6.7M Add +1795.5%
RLAY Relay Therapeutics Inc. 0.32% 358,333 $6.7M New
JANX Janux Therapeutics Inc. 0.31% 420,881 $6.5M Add +41.0%
PLRX Pliant Therapeutics Inc. 0.30% 5,509,724 $6.3M Add +113.1%
WHWK Whitehawk Therapeutics Inc. 0.29% 1,341,394 $6.1M Add +943.9%
KRYS Krystal Biotech Inc. 0.29% 16,420 $6.1M Reduce -18.0%
ABUS Arbutus Biopharma Corp. 0.29% 1,268,147 $6.1M Reduce -59.5%
PFE Pfizer Inc. 0.29% 252,400 $6.1M Add +226.1%
BHF Brighthouse Financial Inc. 0.29% 95,523 $6.0M No change
EWTX Edgewise Therapeutics Inc. 0.28% 143,199 $5.8M Add +58.1%
ALEC Alector Inc. 0.27% 2,883,583 $5.8M Add +174.6%
FULC Fulcrum Therapeutics Inc. 0.27% 1,565,029 $5.7M Add +1098.7%
ARWR Arrowhead Pharmaceuticals Inc. 0.27% 69,800 $5.7M Reduce -0.7%
ABOS Acumen Pharmaceuticals Inc. 0.27% 2,111,334 $5.6M Reduce -2.1%
OACCU Oaktree Acquisition III Life 0.27% 516,482 $5.6M No change
GMED Globus Medical Inc. Class A 0.26% 70,100 $5.5M Add +248.8%
GLUE Monte Rosa Therapeutics Inc. 0.25% 216,752 $5.2M Add +0.5%
DGAC.U Disciplined Growth Acquisiti 0.24% 500,000 $5.0M New
BHAVU Bhav Acquisition Corp. 0.24% 495,000 $5.0M No change
DHR Danaher Corp. 0.23% 25,932 $4.9M Reduce -16.2%
BOLD Boundless Bio Inc. 0.23% 1,968,216 $4.9M New
AVLN Avalyn Pharma Inc. 0.23% 146,447 $4.8M New
SPRY Ars Pharmaceuticals Inc. 0.23% 600,999 $4.8M Reduce -55.9%
ATAI Ataibeckley Inc. 0.23% 913,242 $4.8M No change
PRLD Prelude Therapeutics Inc. 0.23% 900,900 $4.8M Add +489.5%
JATT Jatt II Acquisition Corp. 0.22% 417,724 $4.7M New
RNTX Rein Therapeutics Inc. 0.22% 4,500,000 $4.7M New

Show all 260 holdings

Options reported separately and not counted above: IWM puts ($18.8M), SPY puts ($18.7M), XBI puts ($10.7M), ABVX calls ($5.9M), KVACF calls ($930K), AMLX puts ($720K), RARE calls ($668K), NVO calls ($623K), CRBP calls ($563K), STI calls ($125K).

Other holdings (7): bonds, preferreds, convertibles and warrants · $5.8M (not counted above)
SecurityClassShares / PrincipalValueChange
BRIDGEBIO PHARMA INC (BBIO 2.5 03/15/27) NOTE 2.500% 3/1 · principal 20,000$3.5MNo change
ARROWHEAD RESEARCH CORP (ARWR 0 01/15/32) NOTE 1/1 · principal 10,000$1.2MNew
TRAVERE THERAPEUTICS INC (TVTX 0.5 05/15/32) NOTE 0.500% 5/1 · principal 10,000$1.0MNew
BRIDGEBIO PHARMA INC (BBIO 1.75 03/01/31) NOTE 1.750% 3/0 · principal 30,000$50KNo change
BRIDGEBIO PHARMA INC (BBIO 2.25 02/01/29) NOTE 2.250% 2/0 · principal 45,000$49KNo change
ASPCR A Spac III Acquisition Corp. RIGHT 01/02/2026 215,000$19KNo change
BSAAR Best Spac I Acquisition - RT RIGHT 05/27/2030 100,000$17KNew

Total filed on the 13F, all lines: $2.1B.

Portfolio Sells Q1 2026 → Q2 2026

TERN Terns Pharmaceuticals Inc. Sold out 0.00% −2.92
BEAM Beam Therapeutics Inc. Sold out 0.00% −2.09
SRRK Scholar Rock Holding Corp. Sold out 0.00% −1.21
DNLI Denali Therapeutics Inc. Reduce -45.0% 1.25% −0.93
DBVT DBV Technologies SA-Spon ADR Reduce -47.8% 0.41% −0.87
SNY Sanofi-ADR Reduce -82.0% 0.12% −0.81
PTGX Protagonist Therapeutics Inc. Reduce -3.4% 5.58% −0.78
CYTK Cytokinetics Inc. Reduce -27.6% 1.85% −0.68
ABUS Arbutus Biopharma Corp. Reduce -59.5% 0.29% −0.57
PCVX Vaxcyte Inc. Reduce -43.6% 0.40% −0.51
MLTX Moonlake Immunotherapeutics Reduce -94.1% 0.02% −0.49
INSP Inspire Medical Systems Inc. Reduce -7.5% 0.79% −0.48
SPRY Ars Pharmaceuticals Inc. Reduce -55.9% 0.23% −0.43
AMLX Amylyx Pharmaceuticals Inc. Reduce -50.6% 0.42% −0.42
MPLT Maplight Therapeutics Inc. Reduce -92.9% 0.04% −0.42
VRTX Vertex Pharmaceuticals Inc. Sold out 0.00% −0.41
RYTM Rhythm Pharmaceuticals Inc. Reduce -35.6% 0.72% −0.40
REPL Replimune Group Inc. Reduce -58.6% 0.34% −0.39
CTMX Cytomx Therapeutics Inc. Reduce -1.3% 0.60% −0.37
CGON CG Oncology Inc. Reduce -36.1% 0.40% −0.36
VRDN Viridian Therapeutics Inc. Sold out 0.00% −0.36
XENE Xenon Pharmaceuticals Inc. Reduce -27.2% 0.48% −0.33
VIR Vir Biotechnology Inc. Reduce -10.5% 1.19% −0.31
LLY Eli Lilly & Co. Sold out 0.00% −0.28
DNTH Dianthus Therapeutics Inc. Sold out 0.00% −0.28
BLTE Belite Bio Inc. - ADR Sold out 0.00% −0.26
ROIV Roivant Sciences Ltd. Reduce -3.9% 5.29% −0.23
ACLX Arcellx Inc. Sold out 0.00% −0.22
PRTA Prothena Corp. PLC Reduce -1.7% 0.72% −0.21
AVBP Arrivent Biopharma Inc. Sold out 0.00% −0.20
EVMN Evommune Inc. Reduce -43.5% 0.07% −0.19
APLS Apellis Pharmaceuticals Inc. Sold out 0.00% −0.18
IRD Opus Genetics Inc. Reduce -3.5% 0.35% −0.16
MASI Masimo Corp. Sold out 0.00% −0.16
STRO Sutro Biopharma Inc. Reduce -23.0% 0.64% −0.16
TFX Teleflex Inc. Sold out 0.00% −0.15
IVVD Invivyd Inc. Reduce -0.4% 0.16% −0.14
BIOA Bioage Labs Inc. Sold out 0.00% −0.14
OKUR Onkure Therapeutics Inc. Class A Reduce -8.1% 0.48% −0.13
DHR Danaher Corp. Reduce -16.2% 0.23% −0.12
AEXA American Exceptionalism Class A Reduce -42.5% 0.12% −0.12
ALKS Alkermes PLC Sold out 0.00% −0.10
SEPN Septerna Inc. Reduce -13.7% 1.49% −0.10
SLNO Soleno Therapeutics Inc. Sold out 0.00% −0.10
CNTA Centessa Pharmaceuticals Ltd. Sold out 0.00% −0.09
FOLD Amicus Therapeutics Inc. Sold out 0.00% −0.09
UNH Unitedhealth Group Inc. Sold out 0.00% −0.09
SXT Sensient Technologies Corp. Sold out 0.00% −0.08
SVRA Savara Inc. Reduce -4.2% 0.41% −0.08
SDGR Schrodinger Inc. Sold out 0.00% −0.07

Portfolio Buys Q1 2026 → Q2 2026

ABVX Abivax SA-ADR Add +29.5% 11.39% +1.98
AGIO Agios Pharmaceuticals Inc. Add +815.6% 2.26% +1.97
SPY SS SPDR S&P 500 ETF Trust-US Add +70.0% 4.56% +1.57
ZLAB Zai Lab Ltd.-ADR Add +136.4% 3.03% +1.41
EDIT Editas Medicine Inc. New 1.36% +1.36
PRAX Praxis Precision Medicines I Add +4850.2% 1.18% +1.15
ENTA Enanta Pharmaceuticals Inc. Add +2518.0% 0.93% +0.89
INSM Insmed Inc. Add +545.7% 1.15% +0.80
RLYB Rallybio Corp. Add +4411.1% 0.70% +0.69
QURE Uniqure NV Add +326.1% 0.71% +0.63
VKTX Viking Therapeutics Inc. Add +152.1% 1.06% +0.61
VOR Vor Biopharma Inc. New 0.59% +0.59
ANL Adlai Nortye Group Ltd. Add +763.2% 0.55% +0.50
FTH Faeth Therapeutics Inc. New 0.43% +0.43
MAZE Maze Therapeutics Inc. Add +577.3% 0.48% +0.39
AMAN Amanat Acquisition Corp. Class A New 0.36% +0.36
OVID Ovid Therapeutics Inc. Add +63.2% 0.94% +0.33
BHVN Biohaven Ltd. Add +1020.4% 0.35% +0.33
RACC Research Alliance Corp. Class A New 0.33% +0.33
RLAY Relay Therapeutics Inc. New 0.32% +0.32
IFRX Inflarx NV Add +1795.5% 0.32% +0.31
NRIX Nurix Therapeutics Inc. Add +458.6% 0.36% +0.31
SRPT Sarepta Therapeutics Inc. Add +178.8% 0.62% +0.28
CLDX Celldex Therapeutics Inc. Add +44.8% 1.09% +0.27
ZURA Zura Bio Ltd. Add +179.1% 0.49% +0.26
WHWK Whitehawk Therapeutics Inc. Add +943.9% 0.29% +0.26
CLYM Climb Bio Inc. Add +37.6% 0.51% +0.26
DGAC.U Disciplined Growth Acquisiti New 0.24% +0.24
BOLD Boundless Bio Inc. New 0.23% +0.23
AVLN Avalyn Pharma Inc. New 0.23% +0.23
JATT Jatt II Acquisition Corp. New 0.22% +0.22
RNTX Rein Therapeutics Inc. New 0.22% +0.22
FULC Fulcrum Therapeutics Inc. Add +1098.7% 0.27% +0.21
BBIO Bridgebio Pharma Inc. Add +87.4% 0.62% +0.20
PRLD Prelude Therapeutics Inc. Add +489.5% 0.23% +0.20
APGE Apogee Therapeutics Inc. New 0.19% +0.19
TSHA Taysha Gene Therapies Inc. Add +2.0% 0.98% +0.17
SGMT Sagimet Biosciences Inc. Class A New 0.16% +0.16
GMED Globus Medical Inc. Class A Add +248.8% 0.26% +0.16
PFE Pfizer Inc. Add +226.1% 0.29% +0.16
ELVN Enliven Therapeutics Inc. Add +17.6% 0.93% +0.15
ALEC Alector Inc. Add +174.6% 0.27% +0.14
ZNTL Zentalis Pharmaceuticals Inc. Add +351.3% 0.15% +0.13
MLYS Mineralys Therapeutics Inc. Add +93.2% 0.38% +0.13
SLN Silence Therapeutics PLC-ADR Add +96.5% 0.18% +0.12
EQ Equillium Inc. Add +0.9% 0.57% +0.12
ENGN Engene Therapeutics Inc. Add +1474.6% 0.17% +0.12
XNCR Xencor Inc. Add +148.3% 0.18% +0.11
NKTR Nektar Therapeutics Add +51.4% 0.81% +0.10
EWTX Edgewise Therapeutics Inc. Add +58.1% 0.28% +0.10

Options Activity Q1 2026 → Q2 2026

IWM iShares Russell 2000 ETF put Add +127.3% 62,500 $18.8M
SPY SS SPDR S&P 500 ETF Trust-US put New 25,000 $18.7M
XBI SS SPDR S&P Biotech ETF put Add +349.3% 67,400 $10.7M
TERN Terns Pharmaceuticals Inc. call Sold out 200,000 $10.5Mbefore exit
ABVX Abivax SA-ADR call Add +0.9% 44,400 $5.9M
LQDA Liquidia Corp. put Sold out 100,000 $3.8Mbefore exit
QURE Uniqure NV call Sold out 100,000 $1.6Mbefore exit
KPTI Karyopharm Therapeutics Inc. call Sold out 205,200 $1.1Mbefore exit
REPL Replimune Group Inc. call Sold out 100,000 $765Kbefore exit
AMLX Amylyx Pharmaceuticals Inc. put New 40,100 $720K
GUTS Fractyl Health Inc. call Sold out 1,428,571 $654Kbefore exit
CRBP Corbus Pharmaceuticals Holdi call Add +71.4% 60,000 $563K
MLTX Moonlake Immunotherapeutics call Sold out 20,000 $373Kbefore exit
QUINCE THERAPEUTICS INC put Sold out 50,000 $5Kbefore exit

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

Notes & Other Activity Q1 2026 → Q2 2026

ARROWHEAD RESEARCH CORP (ARWR 0 01/15/32) NOTE 1/1 · principal New 10,000 $1.2M
TRAVERE THERAPEUTICS INC (TVTX 0.5 05/15/32) NOTE 0.500% 5/1 · principal New 10,000 $1.0M
BSAAR Best Spac I Acquisition - RT RIGHT 05/27/2030 New 100,000 $17K

Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 260$2.1BABVX, PTGX, ROIV, SPY, IMVT
Q1 2026 290$1.6BABVX, PTGX, ROIV, IMVT, SPY
Q4 2025Amended 248$1.3BABVX, PTGX, ROIV, IMVT, RNAM
Q3 2025 196$1.0BABVX, KROS, PTGX, ROIV, BOXX
Q2 2025 192$609.1MKROS, PTGX, BOXX, ZLAB, ABVX
Q1 2025 185$505.1MPTGX, BOXX, ROIV, ZLAB, IMVT
Q4 2024 185$469.3MROIV, PTGX, BOXX, ZLAB, IMVT
Q3 2024 244$596.5MCYTK, PTGX, BBIO, BOXX, ROIV
Q2 2024 231$496.6MPTGX, CYTK, ROIV, BOXX, BBIO
Q1 2024 223$366.2MBOXX, ROIV, ALNY, PTGX, CYTK