Alto NeuroscienceANRO
13F holders, Q4 2025 (December 31)97holders +20
26new positions
9sold out
5famous investors
$17.80avg. 13F price*
At the end of Q4 2025, 97 institutions reported holding Alto Neuroscience Inc. (ANRO) in their 13F filings, up 20 from Q3 2025. 26 opened new positions and 9 sold out. The largest holders were Alpha Wave Global, LP ($66.0M), Vestal Point Capital, LP ($44.2M) and Commodore Capital LP ($32.5M). 5 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Alto Neuroscience Inc.
- CUSIP
- 02157Q109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 26 | $68.0M |
| Exits | 9 | $348K |
All 13F filers, Q3 2025 → Q4 2025: 9,097,524 shares bought and 1,510,524 shares sold, net +7,587,000 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 97 holders
| Alpha Wave Global, LP | 8.09% | No change | 3,707,757 | $66.0M |
| Vestal Point Capital, LP | 1.62% | Add +161.6% | 2,485,000 | $44.2M |
| Commodore Capital LP | 2.16% | New | 1,823,196 | $32.5M |
| Perceptive Advisors LLC | 0.58% | Add +1048.5% | 1,784,393 | $31.8M |
| Point72 Asset Management | 0.05% | Add +20.6% | 1,606,954 | $28.6M |
| Armistice Capital, LLC | 0.67% | Reduce -6.1% | 1,536,000 | $27.3M |
| Vanguard Group Inc. | 0.00% | Add +23.6% | 1,365,847 | $24.3M |
| Franklin Resources Inc. | 0.01% | Reduce -3.7% | 1,119,578 | $19.9M |
| Vivo Capital, LLC | 1.19% | New | 1,035,551 | $18.4M |
| 72 Investment Holdings, LLC | 23.50% | No change | 667,778 | $11.9M |
| Millennium Management | 0.01% | Add +99.5% | 629,985 | $11.2M |
| BlackRock, Inc. | 0.00% | Add +65.2% | 607,874 | $10.8M |
| Ikarian Capital, LLC | 1.19% | Add +368.2% | 515,000 | $9.2M |
| Alkeon Capital Management LLC | 0.04% | No change | 477,101 | $8.5M |
| Northern Trust Corp. | 0.00% | Add +2.8% | 474,373 | $8.4M |
| Integral Health Asset Management, LLC | 0.34% | Reduce -6.3% | 375,000 | $6.7M |
| Driehaus Capital Management LLC | 0.04% | New | 336,762 | $6.0M |
| Geode Capital Management, LLC | 0.00% | Add +20.8% | 287,435 | $5.1M |
| Peapod Lane Capital LLC | 3.85% | Reduce -9.9% | 253,992 | $4.5M |
| AWM Investment Company, Inc. | 0.39% | Reduce -19.8% | 225,000 | $4.0M |
| Spruce Street Capital LP | 1.31% | — | 222,844 | $4.0M |
| Jane Street Group, LLC | 0.00% | Add +301.2% | 194,041 | $3.5M |
| Marshall Wace, LLP | 0.00% | Reduce -76.6% | 193,109 | $3.4M |
| Two Sigma Advisers, LP | 0.01% | Add +6.8% | 160,100 | $2.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +73.2% | 156,319 | $2.8M |
| Two Sigma Investments, LP | 0.00% | Add +20.4% | 140,317 | $2.5M |
| Boothbay Fund Management, LLC | 0.07% | Add +329.0% | 139,304 | $2.5M |
| State Street Corp. | 0.00% | Add +26.6% | 130,665 | $2.3M |
| Orbimed Advisors LLC | 0.05% | Reduce -50.0% | 125,000 | $2.2M |
| D. E. Shaw & Co. | 0.00% | New | 124,795 | $2.2M |
| Susquehanna International Group, LLP | 0.00% | Reduce -24.1% | 118,156 | $2.1M |
| Qube Research & Technologies Ltd | 0.00% | New | 112,792 | $2.0M |
| Renaissance Technologies | 0.00% | Add +28.5% | 97,399 | $1.7M |
| Stifel Financial Corp. | 0.00% | Reduce -28.6% | 87,164 | $1.6M |
| Almitas Capital LLC | 0.31% | Reduce -59.8% | 78,520 | $1.4M |
| Bridgeway Capital Management, LLC | 0.03% | No change | 77,653 | $1.4M |
| Ieq Capital, LLC | 0.00% | Add +19.6% | 75,294 | $1.3M |
| Wellington Management Group LLP | 0.00% | New | 69,016 | $1.2M |
| Morgan Stanley | 0.00% | Add +7.5% | 65,581 | $1.2M |
| 683 Capital Management, LLC | 0.10% | New | 64,782 | $1.2M |
| Acadian Asset Management LLC | 0.00% | Add +296.2% | 57,546 | $1.0M |
| AdvisorShares Investments LLC | 0.13% | New | 44,077 | $785K |
| Allianz Asset Management GmbH | 0.00% | Add +16.2% | 43,000 | $765K |
| Quantinno Capital Management LP | 0.00% | No change | 35,579 | $633K |
| Hudson Bay Capital Management LP | 0.00% | New | 34,789 | $619K |
| SCS Capital Management LLC | 0.01% | Reduce -50.0% | 33,389 | $594K |
| BNP Paribas Financial Markets | 0.00% | Add +6365.9% | 33,235 | $592K |
| Dimensional Fund Advisors LP | 0.00% | New | 31,176 | $555K |
| Barclays PLC | 0.00% | Add +72261.9% | 30,392 | $541K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -49.1% | 30,228 | $539K |
| Artia Global Partners LP | 0.08% | New | 29,192 | $520K |
| Citizens Financial Group Inc. | 0.01% | Reduce -29.5% | 28,190 | $502K |
| Alps Advisors Inc. | 0.00% | New | 25,505 | $454K |
| Brown Advisory Inc. | 0.00% | No change | 25,000 | $445K |
| University of Texas/Texas Am Investment Management Co. | 0.06% | No change | 22,175 | $395K |
| XTX Topco Ltd | 0.01% | Add +32.3% | 20,824 | $371K |
| AlphaCore Capital LLC | 0.01% | Add +100.0% | 20,000 | $356K |
| ExodusPoint Capital Management, LP | 0.00% | New | 18,786 | $334K |
| UBS Group AG | 0.00% | Reduce -86.7% | 18,489 | $329K |
| Charles Schwab Investment Management Inc. | 0.00% | New | 17,064 | $304K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -3.3% | 16,485 | $293K |
| Ameriprise Financial Inc. | 0.00% | No change | 13,487 | $240K |
| Citadel Advisors | 0.00% | Reduce -65.1% | 12,973 | $231K |
| Citigroup Inc. | 0.00% | New | 12,566 | $224K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 12,400 | $221K |
| Bank of Montreal | 0.00% | Add +0.1% | 11,355 | $202K |
| Balyasny Asset Management L.P. | 0.00% | New | 11,120 | $198K |
| Bank of America Corp. | 0.00% | Add +8845.2% | 11,092 | $197K |
| American Century Companies Inc. | 0.00% | New | 10,360 | $184K |
| FMR LLC | 0.00% | Reduce -17.0% | 6,374 | $113K |
| AlphaQuest LLC | 0.00% | New | 3,821 | $68K |
| Torren Management, LLC | 0.03% | — | 3,484 | $62K |
| Rothschild Investment LLC | 0.00% | No change | 2,885 | $51K |
| Whittier Trust Co. of Nevada Inc. | 0.00% | No change | 2,482 | $37K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -16.9% | 1,987 | $35K |
| Group One Trading LLC | 0.00% | Reduce -46.8% | 1,413 | $25K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -10.8% | 1,307 | $23K |
| Signaturefd, LLC | 0.00% | New | 1,065 | $19K |
| Federated Hermes, Inc. | 0.00% | Reduce -77.0% | 770 | $14K |
| Wells Fargo & Company | 0.00% | New | 765 | $14K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -8.8% | 661 | $12K |
| Fortitude Family Office, LLC | 0.00% | No change | 511 | $9K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 338 | $6K |
| Russell Investments Group, Ltd. | 0.00% | No change | 306 | $5K |
| North Star Investment Management Corp. | 0.00% | No change | 174 | $3K |
| Cwm, LLC | 0.00% | Reduce -83.3% | 154 | $3K |
| Global Retirement Partners, LLC | 0.00% | New | 150 | $3K |
| JPMorgan Chase & Co. | 0.00% | New | 146 | $3K |
| US Bancorp \de | 0.00% | New | 113 | $2K |
| Cornerstone Financial Management LLC | 0.00% | — | 69 | $1K |
| Royal Bank of Canada | 0.00% | Reduce -82.6% | 34 | $1K |
| Jones Financial Companies LLLP | 0.00% | New | 33 | $587 |
| Farther Finance Advisors, LLC | 0.00% | New | 31 | $552 |
| SHP Wealth Management | 0.00% | — | 25 | $445 |
| Optiver Holding B.V. | 0.00% | No change | 20 | $356 |
| SBI Securities Co., Ltd. | 0.00% | Add +300.0% | 12 | $214 |
| Arax Advisory Partners | 0.00% | Reduce -88.1% | 5 | $89 |
"% of holder's portfolio" is ANRO's weight in each manager's 13F, not the share of Alto Neuroscience Inc. the manager owns.