Ascendis Pharma A/SASND
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 303 institutions reported holding Ascendis Pharma A/S (ASND) in their 13F filings, up 24 from Q3 2025. 52 opened new positions and 36 sold out. The largest holders were Ra Capital Management, L.P. ($2.2B), Westfield Capital Management Co. LP ($1.1B) and Avoro Capital Advisors LLC ($1.1B). 4 famous investors held it, including Ken Griffin (0.1% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Ascendis Pharma A/S
- CUSIP
- 04351P101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 52 | $244.4M |
| Exits | 36 | $176.7M |
All 13F filers, Q3 2025 → Q4 2025: 5,848,362 shares bought and 5,580,280 shares sold, net +268,082 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 303 holders
| Ra Capital Management, L.P. | 22.48% | No change | 10,281,496 | $2.2B |
| Westfield Capital Management Co. LP | 4.61% | Reduce -1.4% | 5,185,696 | $1.1B |
| Avoro Capital Advisors LLC | 10.71% | Add +0.0% | 5,111,111 | $1.1B |
| FMR LLC | 0.05% | Reduce -7.1% | 4,153,311 | $885.7M |
| Janus Henderson Group PLC | 0.39% | Reduce -6.0% | 4,061,641 | $866.1M |
| Artisan Partners Limited Partnership | 1.05% | Reduce -13.3% | 3,225,885 | $687.9M |
| Capital International Investors | 0.10% | Add +0.1% | 3,063,943 | $653.4M |
| Franklin Resources Inc. | 0.10% | Add +20.1% | 1,910,079 | $407.3M |
| Massachusetts Financial Services Co. | 0.13% | Add +0.2% | 1,886,393 | $402.3M |
| Wellington Management Group LLP | 0.07% | Reduce -2.0% | 1,762,721 | $375.9M |
| T. Rowe Price Investment Management, Inc. | 0.22% | Reduce -37.5% | 1,667,625 | $355.6M |
| T. Rowe Price Associates Inc. | 0.04% | Reduce -9.0% | 1,570,260 | $334.8M |
| American Century Companies Inc. | 0.16% | Add +165.0% | 1,443,141 | $307.7M |
| Perceptive Advisors LLC | 4.24% | Reduce -0.7% | 1,081,421 | $230.6M |
| Principal Financial Group Inc. | 0.11% | Add +29.3% | 1,026,407 | $218.9M |
| BlackRock, Inc. | 0.00% | Add +39.1% | 628,200 | $134.0M |
| Morgan Stanley | 0.01% | Add +51.9% | 617,968 | $131.8M |
| Goldman Sachs Group Inc. | 0.02% | Reduce -8.6% | 596,703 | $127.2M |
| Invesco Ltd. | 0.01% | Reduce -36.1% | 586,094 | $125.0M |
| Ameriprise Financial Inc. | 0.03% | Reduce -2.2% | 550,477 | $117.4M |
| Citadel Advisors | 0.08% | Add +1779.6% | 519,516 | $110.8M |
| JPMorgan Chase & Co. | 0.01% | Add +73.5% | 507,240 | $108.2M |
| Nomura Asset Management International Inc. | 0.16% | — | 496,837 | $105.9M |
| FIL Ltd | 0.08% | Add +4.2% | 478,641 | $102.1M |
| Susquehanna International Group, LLP | 0.14% | New | 470,951 | $100.4M |
| Spyglass Capital Management LLC | 4.43% | Add +6.9% | 415,549 | $88.6M |
| Polar Capital Holdings Plc | 0.36% | Reduce -56.8% | 370,473 | $79.0M |
| Fred Alger Management, LLC | 0.29% | Add +106.3% | 352,109 | $75.1M |
| UBS Group AG | 0.01% | Add +57.9% | 308,190 | $65.7M |
| BNP Paribas Financial Markets | 0.04% | Add +28.7% | 307,086 | $65.5M |
| Deutsche Bank AG | 0.02% | Add +326.7% | 296,818 | $63.3M |
| Alliancebernstein L.P. | 0.02% | Reduce -23.2% | 288,592 | $61.5M |
| Sei Investments Co. | 0.06% | Add +37.1% | 281,473 | $60.0M |
| Tri Locum Partners LP | 7.34% | Add +51.6% | 265,015 | $56.5M |
| Millennium Management | 0.04% | Add +50.2% | 262,329 | $55.9M |
| Two Sigma Investments, LP | 0.08% | Add +34.8% | 247,892 | $52.9M |
| Siren, L.L.C. | 1.50% | No change | 235,862 | $50.3M |
| TD Asset Management Inc | 0.04% | Reduce -21.0% | 234,012 | $49.9M |
| Aberdeen Group plc | 0.07% | Add +348.5% | 221,677 | $47.3M |
| Jain Global LLC | 0.47% | Add +502.1% | 216,526 | $46.2M |
| Voloridge Investment Management, LLC | 0.16% | Reduce -7.8% | 216,173 | $46.1M |
| Rock Springs Capital Management LP | 2.23% | Reduce -5.1% | 203,500 | $43.4M |
| Bank of New York Mellon Corp | 0.01% | Reduce -7.0% | 194,605 | $41.5M |
| Qube Research & Technologies Ltd | 0.06% | Reduce -33.3% | 193,464 | $41.3M |
| Q Global Advisors, LLC | 40.11% | Add +11.8% | 190,000 | $40.5M |
| Allspring Global Investments Holdings, LLC | 0.06% | Reduce -2.1% | 187,642 | $40.0M |
| Candriam S.C.A. | 0.20% | Add +4.5% | 186,940 | $39.9M |
| New York State Common Retirement Fund | 0.05% | Add +7.3% | 182,234 | $38.9M |
| PFM Health Sciences, LP | 3.90% | Add +22.3% | 177,685 | $37.9M |
| Vestal Point Capital, LP | 1.37% | Reduce -70.8% | 175,000 | $37.3M |
| ARS Investment Partners, LLC | 2.18% | Reduce -0.6% | 174,611 | $37.2M |
| Orbimed Advisors LLC | 0.75% | Reduce -10.4% | 171,977 | $36.7M |
| Bank of America Corp. | 0.00% | Add +9.8% | 162,503 | $34.7M |
| Driehaus Capital Management LLC | 0.23% | Reduce -12.8% | 156,272 | $33.3M |
| Rice Hall James & Associates, LLC | 1.70% | Reduce -1.4% | 145,046 | $30.9M |
| Frazier Life Sciences Management, L.P. | 0.77% | No change | 133,333 | $28.4M |
| First Turn Management, LLC | 3.21% | Reduce -9.9% | 131,808 | $28.1M |
| Oddo BHF Asset Management Sas | 1.04% | Add +8.3% | 129,941 | $27.7M |
| D. E. Shaw & Co. | 0.02% | Add +3407.2% | 125,768 | $26.8M |
| Moore Capital Management, LP | 0.57% | Add +38.9% | 125,000 | $26.7M |
| Lord, Abbett & Co. LLC | 0.08% | Reduce -20.6% | 120,197 | $25.6M |
| Catalio Capital Management, LP | 4.50% | Reduce -17.7% | 119,265 | $25.4M |
| Braun Stacey Associates Inc. | 0.82% | Add +26.8% | 119,095 | $25.4M |
| IMC-Chicago, LLC | 0.43% | New | 113,682 | $24.2M |
| Loomis Sayles & Co. L P | 0.03% | Reduce -26.8% | 112,240 | $23.9M |
| 1832 Asset Management L.P. | 0.03% | No change | 110,000 | $23.5M |
| Woodline Partners LP | 0.08% | No change | 102,461 | $21.8M |
| Cormorant Asset Management, LP | 1.21% | New | 100,000 | $21.3M |
| Integral Health Asset Management, LLC | 0.97% | Add +50.0% | 90,000 | $19.2M |
| Resolute Capital Asset Partners LLC | 9.13% | Reduce -46.5% | 88,627 | $18.9M |
| Defilade Capital Management, L.P. | 2.48% | — | 85,694 | $18.3M |
| ExodusPoint Capital Management, LP | 0.20% | Add +235.3% | 82,888 | $17.7M |
| Beck Bode, LLC | 2.88% | New | 81,087 | $17.3M |
| Schroder Investment Management Group | 0.01% | Add +119.5% | 73,310 | $15.6M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -4.7% | 73,418 | $15.5M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.02% | Reduce -62.0% | 72,106 | $15.4M |
| Canada Pension Plan Investment Board | 0.01% | Add +169.6% | 71,516 | $15.3M |
| Ensign Peak Advisors, Inc | 0.03% | Reduce -1.6% | 69,560 | $14.8M |
| Voleon Capital Management LP | 0.32% | Add +117.3% | 69,389 | $14.8M |
| Geode Capital Management, LLC | 0.00% | Add +1.2% | 68,855 | $14.7M |
| State Street Corp. | 0.00% | Add +10.4% | 67,949 | $14.5M |
| Castleark Management LLC | 0.42% | Add +55.5% | 66,336 | $14.1M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -8.0% | 60,895 | $12.7M |
| Trexquant Investment LP | 0.11% | Add +114.0% | 59,025 | $12.6M |
| Voya Investment Management LLC | 0.01% | Reduce -22.0% | 57,075 | $12.2M |
| Chevy Chase Trust Holdings, LLC | 0.03% | New | 56,695 | $12.1M |
| Barometer Capital Management Inc. | 2.61% | Add +2241.0% | 91,392 | $10.8M |
| Silverarc Capital Management, LLC | 1.52% | Reduce -8.1% | 49,228 | $10.5M |
| Eversept Partners, LP | 0.58% | New | 48,241 | $10.3M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 0.01% | Reduce -10.5% | 48,097 | $10.3M |
| Brevan Howard Capital Management LP | 0.21% | New | 48,260 | $10.2M |
| Two Sigma Advisers, LP | 0.02% | Add +44.1% | 47,400 | $10.1M |
| Nomura Asset Management Co. Ltd. | 0.02% | Add +57.5% | 43,701 | $9.3M |
| Victory Capital Management Inc. | 0.01% | Reduce -79.3% | 43,190 | $9.2M |
| Diversified Trust Co. | 0.17% | Reduce -7.5% | 42,251 | $9.0M |
| Lazard Asset Management LLC | 0.01% | Reduce -6.2% | 39,135 | $8.3M |
| Skandinaviska Enskilda Banken AB (publ) | 0.03% | Add +35.5% | 38,990 | $8.3M |
| Empowered Funds, LLC | 0.13% | Add +1.7% | 36,697 | $7.8M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -15.8% | 34,910 | $7.4M |
| Wells Fargo & Company | 0.00% | Add +6.7% | 33,780 | $7.2M |
"% of holder's portfolio" is ASND's weight in each manager's 13F, not the share of Ascendis Pharma A/S the manager owns.