Tri Locum Partners LP

In its 13F for Q2 2026 (holdings as of June 30, 2026, filed August 14, 2026), Tri Locum Partners LP reported 19 stock positions worth $813.2 million. Its top holding was Johnson & Johnson (JNJ) at 13.3% of the portfolio, followed by Vertex Pharmaceuticals (VRTX, 12.3%) and Eli Lilly (LLY, 11.3%). Compared with Q1 2026, it opened 4 new positions, sold out of 2, added to 9 and reduced 6. The biggest buy was a new position in Enliven Therapeutics (ELVN) and the biggest sale an exit from Thermo Fisher Scientific (TMO).

Most Recent 13F
Q2 2026
Location
NEW YORK, NY
CIK
0001826434
Portfolio Value
$813.2M (Q2 2026)
SEC Filing
0001826434-26-000005 ↗ filed Aug 14, 2026

Holdings Value

0$200.0M$400.0M$600.0M$800.0M$1.0B Q1 2024: $288.4M Q1 2024 Q2 2024: $395.5M Q2 2024 Q3 2024: $417.4M Q3 2024 Q4 2024: $482.7M Q4 2024 Q1 2025: $194.9M Q1 2025 Q2 2025: $329.5M Q2 2025 Q3 2025: $435.1M Q3 2025 Q4 2025: $770.1M Q4 2025 Q1 2026: $712.5M Q1 2026 Q2 2026: $813.2M $813.2M Q2 2026

Holdings 19 stocks · $813.2M

JNJ Johnson & Johnson 13.27% 424,945 $107.9M Add +2.5%
VRTX Vertex Pharmaceuticals Inc. 12.33% 201,791 $100.2M Add +56.0%
LLY Eli Lilly & Co. 11.29% 76,532 $91.8M Add +23.9%
ASND Ascendis Pharma A/S 8.49% 258,740 $69.0M Add +1.3%
DXCM Dexcom Inc. 6.80% 820,479 $55.3M Add +17.5%
AXSM Axsome Therapeutics Inc. 6.60% 219,308 $53.7M Add +253.1%
JAZZ Jazz Pharmaceuticals PLC 6.57% 221,720 $53.4M Add +39.7%
ELVN Enliven Therapeutics Inc. 5.41% 866,716 $44.0M New
ARGX Argenx SE - ADR 4.75% 41,596 $38.6M Add +31.5%
MDGL Madrigal Pharmaceuticals Inc. 4.51% 68,273 $36.7M Reduce -33.9%
RVMD Revolution Medicines Inc. 3.50% 151,822 $28.4M New
UTHR United Therapeutics Corp. 3.13% 47,026 $25.5M Reduce -33.2%
TEVA Teva Pharmaceutical-SP ADR 3.11% 746,835 $25.3M Reduce -26.9%
TARS Tarsus Pharmaceuticals Inc. 2.54% 328,340 $20.7M Add +30.0%
ISRG Intuitive Surgical Inc. 2.35% 47,983 $19.1M Reduce -68.7%
CYTK Cytokinetics Inc. 2.03% 194,000 $16.5M New
DNTH Dianthus Therapeutics Inc. 1.45% 120,712 $11.8M Reduce -17.1%
BBNX Beta Bionics Inc. 0.95% 493,344 $7.7M New
DFTX Definium Therapeutics Inc. 0.94% 162,996 $7.7M Reduce -55.9%

Portfolio Sells Q1 2026 → Q2 2026

TMO Thermo Fisher Scientific Inc. Sold out 0.00% −9.13
ISRG Intuitive Surgical Inc. Reduce -68.7% 2.35% −7.57
NUVL Nuvalent Inc. Class A Sold out 0.00% −4.44
MDGL Madrigal Pharmaceuticals Inc. Reduce -33.9% 4.51% −3.08
UTHR United Therapeutics Corp. Reduce -33.2% 3.13% −2.72
TEVA Teva Pharmaceutical-SP ADR Reduce -26.9% 3.11% −1.20
DNTH Dianthus Therapeutics Inc. Reduce -17.1% 1.45% −0.27
DFTX Definium Therapeutics Inc. Reduce -55.9% 0.94% −0.04

Portfolio Buys Q1 2026 → Q2 2026

ELVN Enliven Therapeutics Inc. New 5.41% +5.41
AXSM Axsome Therapeutics Inc. Add +253.1% 6.60% +5.13
VRTX Vertex Pharmaceuticals Inc. Add +56.0% 12.33% +4.22
RVMD Revolution Medicines Inc. New 3.50% +3.50
LLY Eli Lilly & Co. Add +23.9% 11.29% +3.31
JAZZ Jazz Pharmaceuticals PLC Add +39.7% 6.57% +2.36
CYTK Cytokinetics Inc. New 2.03% +2.03
ARGX Argenx SE - ADR Add +31.5% 4.75% +1.50
BBNX Beta Bionics Inc. New 0.95% +0.95
DXCM Dexcom Inc. Add +17.5% 6.80% +0.64
ASND Ascendis Pharma A/S Add +1.3% 8.49% +0.29
TARS Tarsus Pharmaceuticals Inc. Add +30.0% 2.54% +0.05
JNJ Johnson & Johnson Add +2.5% 13.27% −0.95

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 19$813.2MJNJ, VRTX, LLY, ASND, DXCM
Q1 2026 17$712.5MJNJ, ISRG, TMO, ASND, VRTX
Q4 2025 15$770.1MJNJ, DHR, LLY, UTHR, ASND
Q3 2025 18$435.1MJNJ, UTHR, MRK, AXSM, ASND
Q2 2025 23$329.5MTEVA, MDGL, ALNY, ARGX, ASND
Q1 2025 22$194.9MCI, MCK, SLNO, TEVA, INSP
Q4 2024 28$482.7MTEVA, ZBH, ARGX, NTRA, INSP
Q3 2024 20$417.4MPFE, TEVA, NTRA, STVN, ARGX
Q2 2024 25$395.5MTEVA, ARGX, ASND, AMGN, NTRA
Q1 2024 27$288.4MTEVA, AVDL, SILK, NTRA, ASND