C4 TherapeuticsCCCC
13F holders, Q2 2025 (June 30)At the end of Q2 2025, 102 institutions reported holding C4 Therapeutics Inc. (CCCC) in their 13F filings, down 13 from Q1 2025. 25 opened new positions and 39 sold out. The largest holders were Wasatch Advisors LP ($10.6M), Lynx1 Capital Management LP ($10.2M) and Soleus Capital Management, L.P. ($10.0M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- C4 Therapeutics Inc.
- CUSIP
- 12529R107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 25 | $1.3M |
| Exits | 39 | $9.1M |
All 13F filers, Q1 2025 → Q2 2025: 6,365,247 shares bought and 15,787,637 shares sold, net −9,422,390 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 102 holders
| Wasatch Advisors LP | 0.06% | Add +10.4% | 7,424,662 | $10.6M |
| Lynx1 Capital Management LP | 2.93% | No change | 7,098,133 | $10.2M |
| Soleus Capital Management, L.P. | 0.69% | No change | 6,978,942 | $10.0M |
| Orbimed Advisors LLC | 0.25% | No change | 6,830,300 | $9.8M |
| Morgan Stanley | 0.00% | Add +17.5% | 4,754,188 | $6.8M |
| Vanguard Group Inc. | 0.00% | Reduce -10.5% | 3,018,022 | $4.3M |
| Bank of America Corp. | 0.00% | Add +0.9% | 2,008,004 | $2.9M |
| BlackRock, Inc. | 0.00% | Reduce -65.4% | 1,828,614 | $2.6M |
| Bain Capital Life Sciences Investors, LLC | 0.20% | No change | 1,111,910 | $1.6M |
| Millennium Management | 0.00% | Add +1571.3% | 1,101,342 | $1.6M |
| Renaissance Technologies | 0.00% | Add +409.6% | 1,093,188 | $1.6M |
| Tang Capital Management LLC | 0.07% | No change | 900,000 | $1.3M |
| Goldman Sachs Group Inc. | 0.00% | Add +41.4% | 880,258 | $1.3M |
| Two Sigma Advisers, LP | 0.00% | Add +1.4% | 811,400 | $1.2M |
| Geode Capital Management, LLC | 0.00% | Reduce -47.9% | 745,053 | $1.1M |
| Two Sigma Investments, LP | 0.00% | Add +32.8% | 683,599 | $978K |
| UBS Group AG | 0.00% | Reduce -34.5% | 572,026 | $818K |
| Jane Street Group, LLC | 0.00% | Add +3816.8% | 492,612 | $704K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -36.7% | 441,735 | $632K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -16.0% | 431,888 | $617K |
| AQR Capital Management | 0.00% | Add +173.1% | 383,789 | $549K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -30.1% | 331,897 | $475K |
| State Street Corp. | 0.00% | Reduce -76.5% | 287,373 | $411K |
| Cubist Systematic Strategies, LLC | 0.00% | New | 239,959 | $343K |
| Royal Bank of Canada | 0.00% | Add +4193.9% | 238,957 | $342K |
| Hennion & Walsh Asset Management, Inc. | 0.01% | Reduce -4.4% | 208,766 | $299K |
| BNP Paribas Financial Markets | 0.00% | Add +1039.3% | 206,177 | $295K |
| ArrowMark Colorado Holdings LLC | 0.01% | Reduce -84.1% | 204,505 | $292K |
| FMR LLC | 0.00% | Add +3.9% | 201,358 | $288K |
| Adage Capital Partners Gp, L.L.C. | 0.00% | Reduce -87.1% | 200,000 | $286K |
| LPL Financial LLC | 0.00% | Add +1.2% | 196,255 | $281K |
| Atom Investors LP | 0.02% | Reduce -29.3% | 190,182 | $272K |
| Invesco Ltd. | 0.00% | Add +11.1% | 155,017 | $222K |
| Squarepoint Ops LLC | 0.00% | New | 143,687 | $205K |
| Susquehanna International Group, LLP | 0.00% | Add +91.2% | 141,056 | $202K |
| Northern Trust Corp. | 0.00% | Reduce -72.0% | 139,673 | $200K |
| Acadian Asset Management LLC | 0.00% | Add +404.9% | 139,723 | $198K |
| Jain Global LLC | 0.00% | Add +462.8% | 136,219 | $195K |
| Mariner, LLC | 0.00% | Reduce -26.4% | 132,765 | $190K |
| Susquehanna Portfolio Strategies, LLC | 0.00% | New | 126,900 | $181K |
| XTX Topco Ltd | 0.01% | Add +170.0% | 108,278 | $155K |
| Bridgeway Capital Management, LLC | 0.00% | Reduce -19.3% | 104,900 | $150K |
| D. E. Shaw & Co. | 0.00% | Add +12.9% | 89,475 | $128K |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | 0.08% | No change | 85,000 | $122K |
| Man Group plc | 0.00% | Reduce -8.3% | 78,487 | $112K |
| Aster Capital Management (DIFC) Ltd | 0.03% | New | 77,734 | $111K |
| HRT Financial LP | 0.00% | Add +445.5% | 71,106 | $101K |
| Susquehanna Fundamental Investments, LLC | 0.00% | Reduce -68.1% | 67,617 | $97K |
| Y-Intercept (Hong Kong) Ltd | 0.00% | New | 52,521 | $75K |
| Barclays PLC | 0.00% | Reduce -57.4% | 45,823 | $66K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.01% | Add +4344600.0% | 43,447 | $62K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +458.0% | 40,592 | $58K |
| Intrepid Family Office LLC | 0.06% | No change | 40,000 | $57K |
| R Squared Ltd | 0.02% | New | 30,587 | $44K |
| Brookstone Capital Management | 0.00% | New | 29,325 | $42K |
| Crestwood Advisors Group, LLC | 0.00% | New | 29,000 | $41K |
| Catalyst Funds Management Pty Ltd | 0.01% | New | 28,300 | $40K |
| Farallon Capital Management, L.L.C. | 0.00% | No change | 28,000 | $40K |
| Cresset Asset Management, LLC | 0.00% | Reduce -3.8% | 25,000 | $36K |
| HSBC Holdings PLC | 0.00% | Reduce -1.3% | 25,157 | $36K |
| Virtu Financial LLC | 0.00% | New | 24,377 | $35K |
| Bank of Montreal | 0.00% | Add +16.4% | 24,200 | $35K |
| Citigroup Inc. | 0.00% | Reduce -47.4% | 22,816 | $33K |
| Dynamic Technology Lab Private Ltd | 0.00% | New | 21,476 | $31K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -19.1% | 21,111 | $30K |
| Ieq Capital, LLC | 0.00% | Add +3.5% | 18,822 | $27K |
| Captrust Financial Advisors | 0.00% | Add +3.9% | 17,039 | $24K |
| Ewa, LLC | 0.01% | New | 16,643 | $24K |
| Hudson Bay Capital Management LP | 0.00% | New | 16,095 | $23K |
| DRW Securities, LLC | 0.00% | New | 15,836 | $23K |
| Ethic Inc. | 0.00% | New | 15,164 | $21K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -24.9% | 14,720 | $21K |
| China Universal Asset Management Co., Ltd. | 0.00% | Add +0.1% | 14,261 | $20K |
| Quadrature Capital Ltd | 0.00% | Reduce -15.4% | 13,547 | $19K |
| Corient Private Wealth LP | 0.00% | Reduce -0.4% | 12,695 | $18K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -67.5% | 12,400 | $18K |
| Gsa Capital Partners LLP | 0.00% | Reduce -75.0% | 10,963 | $16K |
| B. Riley Wealth Advisors, Inc. | 0.00% | No change | 11,000 | $16K |
| US Bancorp \de | 0.00% | Reduce -5.2% | 11,000 | $16K |
| Two Sigma Securities, LLC | 0.00% | New | 10,589 | $15K |
| Cwm, LLC | 0.00% | Reduce -29.6% | 10,156 | $15K |
| Engineers Gate Manager LP | 0.00% | New | 10,418 | $15K |
| Abel Hall, LLC | 0.01% | New | 10,225 | $15K |
| JPMorgan Chase & Co. | 0.00% | Reduce -86.6% | 4,606 | $7K |
| Point72 (DIFC) Ltd | 0.00% | New | 3,953 | $6K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +15.5% | 2,743 | $4K |
| Rhumbline Advisers | 0.00% | Reduce -97.0% | 2,716 | $4K |
| Summit Securities Group LLC | 0.00% | Add +1269.0% | 2,122 | $3K |
| GF Fund Management Co. LTD. | 0.00% | No change | 1,751 | $3K |
| Wells Fargo & Company | 0.00% | Reduce -99.7% | 1,529 | $2K |
| Osaic Holdings, Inc. | 0.00% | New | 1,500 | $2K |
| Syntax Research, Inc. | 0.00% | No change | 1,000 | $1K |
| Nisa Investment Advisors, LLC | 0.00% | Add +163.8% | 430 | $615 |
| Fortitude Family Office, LLC | 0.00% | New | 325 | $465 |
| EverSource Wealth Advisors, LLC | 0.00% | Add +839.4% | 310 | $444 |
| Brooklyn Investment Group | 0.00% | New | 295 | $422 |
| SBI Securities Co., Ltd. | 0.00% | No change | 150 | $215 |
| Raymond James Financial Inc. | 0.00% | New | 135 | $193 |
| Essential Partners LLC | 0.00% | — | 133 | $190 |
| IFP Advisors, Inc | 0.00% | New | 34 | $48 |
| True Wealth Design, LLC | 0.00% | Add +244.4% | 31 | $45 |
| Group One Trading LLC | 0.00% | New | 15 | $21 |
"% of holder's portfolio" is CCCC's weight in each manager's 13F, not the share of C4 Therapeutics Inc. the manager owns.