C4 TherapeuticsCCCC
13F holders, Q3 2025 (September 30)97holders −5
21new positions
26sold out
4famous investors
$2.22avg. 13F price*
At the end of Q3 2025, 97 institutions reported holding C4 Therapeutics Inc. (CCCC) in their 13F filings, down 5 from Q2 2025. 21 opened new positions and 26 sold out. The largest holders were Lynx1 Capital Management LP ($15.8M), Soleus Capital Management, L.P. ($15.7M) and Orbimed Advisors LLC ($11.6M). 4 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- C4 Therapeutics Inc.
- CUSIP
- 12529R107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 21 | $7.6M |
| Exits | 26 | $1.9M |
All 13F filers, Q2 2025 → Q3 2025: 5,753,071 shares bought and 7,903,647 shares sold, net −2,150,576 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 97 holders
| Lynx1 Capital Management LP | 3.21% | No change | 7,098,133 | $15.8M |
| Soleus Capital Management, L.P. | 0.84% | Add +1.1% | 7,053,942 | $15.7M |
| Orbimed Advisors LLC | 0.28% | Reduce -23.4% | 5,235,146 | $11.6M |
| Morgan Stanley | 0.00% | Add +4.6% | 4,972,032 | $11.0M |
| Wasatch Advisors LP | 0.06% | Reduce -34.6% | 4,852,741 | $10.8M |
| Vanguard Group Inc. | 0.00% | Add +5.8% | 3,191,557 | $7.1M |
| Bank of America Corp. | 0.00% | Add +2.3% | 2,053,162 | $4.6M |
| Millennium Management | 0.00% | Add +75.6% | 1,934,225 | $4.3M |
| Silverarc Capital Management, LLC | 0.61% | New | 1,897,383 | $4.2M |
| BlackRock, Inc. | 0.00% | Reduce -12.7% | 1,595,639 | $3.5M |
| Bain Capital Life Sciences Investors, LLC | 0.16% | No change | 1,111,910 | $2.5M |
| Renaissance Technologies | 0.00% | Reduce -14.3% | 936,950 | $2.1M |
| Tang Capital Management LLC | 0.08% | No change | 900,000 | $2.0M |
| Two Sigma Investments, LP | 0.00% | Add +22.1% | 834,726 | $1.9M |
| Two Sigma Advisers, LP | 0.00% | Reduce -6.0% | 763,100 | $1.7M |
| Geode Capital Management, LLC | 0.00% | Reduce -2.6% | 725,304 | $1.6M |
| Susquehanna International Group, LLP | 0.00% | Add +265.4% | 515,437 | $1.1M |
| Jacobs Levy Equity Management, Inc. | 0.00% | Add +13.9% | 503,145 | $1.1M |
| Citadel Advisors | 0.00% | New | 481,449 | $1.1M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -47.8% | 459,893 | $1.0M |
| Shay Capital LLC | 0.17% | New | 420,000 | $932K |
| Charles Schwab Investment Management Inc. | 0.00% | Add +5.6% | 350,606 | $778K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -19.1% | 349,289 | $775K |
| State Street Corp. | 0.00% | No change | 287,373 | $638K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | Add +114.4% | 272,053 | $604K |
| FMR LLC | 0.00% | Add +5.0% | 211,348 | $469K |
| Hennion & Walsh Asset Management, Inc. | 0.02% | Reduce -1.8% | 205,033 | $455K |
| ArrowMark Colorado Holdings LLC | 0.01% | No change | 204,505 | $454K |
| Jane Street Group, LLC | 0.00% | Reduce -58.7% | 203,568 | $452K |
| LPL Financial LLC | 0.00% | Add +2.4% | 200,930 | $446K |
| Invesco Ltd. | 0.00% | Add +23.7% | 191,820 | $426K |
| Royal Bank of Canada | 0.00% | Reduce -23.6% | 182,640 | $405K |
| XTX Topco Ltd | 0.02% | Add +38.5% | 149,962 | $333K |
| Cubist Systematic Strategies, LLC | 0.00% | Reduce -42.2% | 138,657 | $308K |
| Northern Trust Corp. | 0.00% | Reduce -1.0% | 138,319 | $307K |
| Mariner, LLC | 0.00% | Reduce -3.4% | 128,237 | $285K |
| Acadian Asset Management LLC | 0.00% | Reduce -8.3% | 128,108 | $282K |
| Qube Research & Technologies Ltd | 0.00% | New | 115,973 | $257K |
| Algert Global LLC | 0.00% | New | 106,300 | $236K |
| Marshall Wace, LLP | 0.00% | New | 106,275 | $236K |
| Man Group plc | 0.00% | Add +15.0% | 90,278 | $200K |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | 0.11% | No change | 85,000 | $189K |
| State of Wyoming | 0.02% | New | 82,509 | $183K |
| BNP Paribas Financial Markets | 0.00% | Reduce -60.8% | 80,806 | $179K |
| Bridgeway Capital Management, LLC | 0.00% | Reduce -23.8% | 79,900 | $177K |
| Intrepid Family Office LLC | 0.14% | Add +75.0% | 70,000 | $155K |
| Susquehanna Fundamental Investments, LLC | 0.01% | No change | 67,617 | $150K |
| Crestwood Advisors Group, LLC | 0.00% | Add +129.4% | 66,536 | $148K |
| UBS Group AG | 0.00% | Reduce -89.2% | 61,650 | $137K |
| Barclays PLC | 0.00% | Reduce -6.0% | 43,062 | $96K |
| Catalyst Funds Management Pty Ltd | 0.01% | Add +50.2% | 42,500 | $94K |
| Graham Capital Management, L.P. | 0.00% | New | 40,628 | $90K |
| Jefferies Financial Group Inc. | 0.00% | New | 38,200 | $85K |
| Voleon Capital Management LP | 0.00% | New | 28,420 | $63K |
| Farallon Capital Management, L.L.C. | 0.00% | No change | 28,000 | $62K |
| Cresset Asset Management, LLC | 0.00% | No change | 25,000 | $56K |
| American Century Companies Inc. | 0.00% | New | 24,248 | $54K |
| Corient Private Wealth LP | 0.00% | Add +78.8% | 22,702 | $50K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.01% | Reduce -50.0% | 21,708 | $48K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -2.9% | 20,510 | $46K |
| Ewa, LLC | 0.01% | Add +17.2% | 19,510 | $43K |
| Caitong International Asset Management Co., Ltd | 0.03% | New | 19,146 | $43K |
| Wells Fargo & Company | 0.00% | Add +1120.4% | 18,660 | $41K |
| R Squared Ltd | 0.02% | Reduce -41.5% | 17,880 | $40K |
| Engineers Gate Manager LP | 0.00% | Add +56.3% | 16,286 | $36K |
| Captrust Financial Advisors | 0.00% | Reduce -12.6% | 14,889 | $33K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -1.0% | 14,574 | $32K |
| Prudential Financial Inc. | 0.00% | New | 14,300 | $32K |
| HSBC Holdings PLC | 0.00% | Reduce -45.8% | 13,629 | $30K |
| Zacks Investment Management | 0.00% | New | 13,043 | $29K |
| Wolverine Trading, LLC | 0.00% | New | 12,710 | $28K |
| T. Rowe Price Associates Inc. | 0.00% | No change | 12,400 | $28K |
| China Universal Asset Management Co., Ltd. | 0.00% | Reduce -12.5% | 12,475 | $28K |
| Group One Trading LLC | 0.00% | Add +82780.0% | 12,432 | $28K |
| D. E. Shaw & Co. | 0.00% | Reduce -86.7% | 11,863 | $26K |
| B. Riley Wealth Advisors, Inc. | 0.00% | No change | 11,000 | $24K |
| Ethic Inc. | 0.00% | Reduce -30.7% | 10,508 | $23K |
| Simplicity Wealth,LLC | 0.00% | New | 10,213 | $23K |
| Abel Hall, LLC | 0.01% | Reduce -0.8% | 10,140 | $23K |
| Squarepoint Ops LLC | 0.00% | Reduce -93.0% | 10,099 | $22K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -79.3% | 8,414 | $19K |
| Simplex Trading, LLC | 0.00% | New | 7,836 | $17K |
| Osaic Holdings, Inc. | 0.00% | Add +202.0% | 4,530 | $11K |
| JPMorgan Chase & Co. | 0.00% | Reduce -3.8% | 4,429 | $10K |
| Citigroup Inc. | 0.00% | Reduce -85.7% | 3,264 | $7K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.3% | 2,751 | $6K |
| Rhumbline Advisers | 0.00% | No change | 2,716 | $6K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -16.4% | 1,463 | $3K |
| JFS Wealth Advisors, LLC | 0.00% | New | 1,000 | $2K |
| Point72 (DIFC) Ltd | 0.00% | Reduce -94.1% | 234 | $519 |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -63.7% | 156 | $346 |
| SBI Securities Co., Ltd. | 0.00% | Add +1.3% | 152 | $337 |
| Wealthspire Advisors, LLC | 0.00% | New | 100 | $222 |
| Advisory Services Network, LLC | 0.00% | New | 74 | $164 |
| Arax Advisory Partners | 0.00% | New | 55 | $122 |
| IFP Advisors, Inc | 0.00% | Reduce -50.0% | 17 | $38 |
| Cwm, LLC | 0.00% | Reduce -98.6% | 146 | $0 |
"% of holder's portfolio" is CCCC's weight in each manager's 13F, not the share of C4 Therapeutics Inc. the manager owns.