C4 TherapeuticsCCCC
13F holders, Q4 2025 (December 31)101holders +4
23new positions
16sold out
5famous investors
$1.91avg. 13F price*
At the end of Q4 2025, 101 institutions reported holding C4 Therapeutics Inc. (CCCC) in their 13F filings, up 4 from Q3 2025. 23 opened new positions and 16 sold out. The largest holders were Point72 Asset Management ($18.0M), Morgan Stanley ($17.2M) and Ra Capital Management, L.P. ($15.3M). 5 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- C4 Therapeutics Inc.
- CUSIP
- 12529R107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 23 | $36.4M |
| Exits | 16 | $4.7M |
All 13F filers, Q3 2025 → Q4 2025: 38,331,188 shares bought and 10,881,606 shares sold, net +27,449,582 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 101 holders
| Point72 Asset Management | 0.03% | New | 9,439,328 | $18.0M |
| Morgan Stanley | 0.00% | Add +80.6% | 8,981,662 | $17.2M |
| Ra Capital Management, L.P. | 0.16% | New | 8,000,000 | $15.3M |
| Bain Capital Life Sciences Investors, LLC | 1.05% | Add +545.0% | 7,171,910 | $13.7M |
| Lynx1 Capital Management LP | 2.74% | No change | 7,098,133 | $13.6M |
| Vanguard Group Inc. | 0.00% | Add +37.2% | 4,379,815 | $8.4M |
| Wasatch Advisors LP | 0.05% | Reduce -10.5% | 4,344,918 | $8.3M |
| Soleus Capital Management, L.P. | 0.31% | Reduce -46.1% | 3,803,942 | $7.3M |
| Bank of America Corp. | 0.00% | Add +16.3% | 2,387,586 | $4.6M |
| Silverarc Capital Management, LLC | 0.55% | Add +5.1% | 1,994,224 | $3.8M |
| BlackRock, Inc. | 0.00% | Add +23.4% | 1,969,814 | $3.8M |
| Susquehanna International Group, LLP | 0.00% | Add +244.5% | 1,775,783 | $3.4M |
| Renaissance Technologies | 0.00% | Add +71.0% | 1,602,580 | $3.1M |
| Two Sigma Investments, LP | 0.00% | Add +80.8% | 1,509,603 | $2.9M |
| Orbimed Advisors LLC | 0.05% | Reduce -73.2% | 1,404,902 | $2.7M |
| Millennium Management | 0.00% | Reduce -38.5% | 1,188,969 | $2.3M |
| Goldman Sachs Group Inc. | 0.00% | Add +136.8% | 1,089,020 | $2.1M |
| Two Sigma Advisers, LP | 0.00% | Add +40.0% | 1,068,200 | $2.0M |
| Geode Capital Management, LLC | 0.00% | Add +36.3% | 988,878 | $1.9M |
| Jane Street Group, LLC | 0.00% | Add +329.7% | 874,794 | $1.7M |
| Wells Fargo & Company | 0.00% | Add +4236.9% | 809,260 | $1.5M |
| Acadian Asset Management LLC | 0.00% | Add +413.0% | 657,173 | $1.3M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +28.2% | 449,432 | $858K |
| Citadel Advisors | 0.00% | Reduce -7.0% | 447,808 | $855K |
| Walleye Capital LLC | 0.01% | New | 443,341 | $847K |
| 683 Capital Management, LLC | 0.07% | New | 400,000 | $764K |
| State Street Corp. | 0.00% | Add +19.3% | 342,773 | $655K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -15.1% | 296,480 | $566K |
| Qube Research & Technologies Ltd | 0.00% | Add +150.3% | 290,234 | $554K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | No change | 272,053 | $520K |
| Invesco Ltd. | 0.00% | Add +39.9% | 268,350 | $513K |
| Marshall Wace, LLP | 0.00% | Add +149.4% | 265,027 | $506K |
| FMR LLC | 0.00% | Add +20.4% | 254,406 | $486K |
| LPL Financial LLC | 0.00% | Add +21.1% | 243,305 | $465K |
| Hennion & Walsh Asset Management, Inc. | 0.02% | Add +15.7% | 237,137 | $453K |
| Barclays PLC | 0.00% | Add +409.0% | 219,204 | $419K |
| ArrowMark Colorado Holdings LLC | 0.01% | No change | 204,505 | $391K |
| Northern Trust Corp. | 0.00% | Add +20.2% | 166,207 | $317K |
| Man Group plc | 0.00% | Add +72.9% | 156,098 | $298K |
| Squarepoint Ops LLC | 0.00% | Add +1247.2% | 136,054 | $260K |
| Quadrature Capital Ltd | 0.00% | New | 133,112 | $254K |
| Bridgeway Capital Management, LLC | 0.01% | Add +64.1% | 131,100 | $250K |
| Mariner, LLC | 0.00% | Reduce -0.1% | 128,050 | $245K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 117,700 | $225K |
| Hudson Bay Capital Management LP | 0.00% | New | 111,551 | $213K |
| Atom Investors LP | 0.02% | New | 104,964 | $200K |
| XTX Topco Ltd | 0.01% | Reduce -30.3% | 104,458 | $200K |
| Graham Capital Management, L.P. | 0.01% | Add +151.6% | 102,198 | $195K |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | 0.08% | No change | 85,000 | $162K |
| American Century Companies Inc. | 0.00% | Add +181.4% | 68,245 | $130K |
| Susquehanna Fundamental Investments, LLC | 0.00% | No change | 67,617 | $129K |
| Crestwood Advisors Group, LLC | 0.00% | No change | 66,536 | $127K |
| ExodusPoint Capital Management, LP | 0.00% | New | 62,165 | $119K |
| Intrepid Family Office LLC | 0.10% | Reduce -21.4% | 55,000 | $105K |
| D. E. Shaw & Co. | 0.00% | Add +345.8% | 52,879 | $101K |
| UBS Group AG | 0.00% | Reduce -14.4% | 52,752 | $101K |
| Citigroup Inc. | 0.00% | Add +1427.0% | 49,840 | $95K |
| Catalyst Funds Management Pty Ltd | 0.02% | No change | 42,500 | $81K |
| Group One Trading LLC | 0.00% | Add +213.7% | 38,994 | $74K |
| Focus Partners Wealth | 0.00% | New | 38,187 | $73K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | New | 37,721 | $72K |
| Jefferies Financial Group Inc. | 0.00% | Reduce -7.5% | 35,340 | $67K |
| Lighthouse Investment Partners, LLC | 0.00% | New | 33,660 | $64K |
| Callan Family Office, LLC | 0.00% | New | 31,743 | $61K |
| Simplex Trading, LLC | 0.00% | Add +291.3% | 30,658 | $59K |
| Canada Pension Plan Investment Board | 0.00% | New | 29,500 | $56K |
| Farallon Capital Management, L.L.C. | 0.00% | No change | 28,000 | $53K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +208.8% | 25,980 | $50K |
| Cresset Asset Management, LLC | 0.00% | No change | 25,000 | $48K |
| Engineers Gate Manager LP | 0.00% | Add +49.9% | 24,416 | $47K |
| Corient Private Wealth LP | 0.00% | Reduce -5.8% | 21,387 | $41K |
| Virtu Financial LLC | 0.00% | New | 20,655 | $39K |
| Delta Investment Management, LLC | 0.01% | New | 20,000 | $38K |
| Ewa, LLC | 0.01% | Reduce -13.4% | 16,889 | $32K |
| China Universal Asset Management Co., Ltd. | 0.00% | Add +26.6% | 15,792 | $30K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +4.5% | 15,224 | $29K |
| Prudential Financial Inc. | 0.00% | Add +5.2% | 15,050 | $29K |
| HSBC Holdings PLC | 0.00% | No change | 13,629 | $26K |
| R Squared Ltd | 0.01% | Reduce -23.5% | 13,674 | $26K |
| Northern Lights Advisors, Inc. | 0.02% | — | 12,930 | $25K |
| Jain Global LLC | 0.00% | New | 12,762 | $24K |
| T. Rowe Price Associates Inc. | 0.00% | No change | 12,400 | $24K |
| NINE MASTS CAPITAL Ltd | 0.00% | New | 11,472 | $22K |
| Ethic Inc. | 0.00% | Reduce -2.2% | 10,278 | $20K |
| Simplicity Wealth,LLC | 0.00% | Reduce -0.1% | 10,202 | $19K |
| Abel Hall, LLC | 0.00% | No change | 10,140 | $19K |
| Bronte Capital Management Pty Ltd. | 0.00% | New | 10,033 | $19K |
| Blackston Financial Advisory Group, LLC | 0.01% | New | 10,000 | $19K |
| JPMorgan Chase & Co. | 0.00% | Add +34.2% | 5,945 | $11K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +71.2% | 4,709 | $9K |
| Osaic Holdings, Inc. | 0.00% | Add +0.3% | 4,544 | $9K |
| Lanark Financial, Inc. | 0.00% | New | 4,000 | $8K |
| Rhumbline Advisers | 0.00% | No change | 2,716 | $5K |
| BNP Paribas Financial Markets | 0.00% | Reduce -97.3% | 2,161 | $4K |
| GF Fund Management Co. LTD. | 0.00% | Add +30.1% | 1,903 | $4K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 1,000 | $2K |
| Royal Bank of Canada | 0.00% | Reduce -99.6% | 671 | $1K |
| Optima Capital LLC | 0.00% | New | 226 | $432 |
| Nisa Investment Advisors, LLC | 0.00% | No change | 156 | $298 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -34.2% | 100 | $191 |
| Arax Advisory Partners | 0.00% | Reduce -65.5% | 19 | $36 |
"% of holder's portfolio" is CCCC's weight in each manager's 13F, not the share of C4 Therapeutics Inc. the manager owns.