Opus GeneticsIRD
13F holders, Q4 2025 (December 31)59holders +11
15new positions
5sold out
3famous investors
$2.01avg. 13F price*
At the end of Q4 2025, 59 institutions reported holding Opus Genetics Inc. (IRD) in their 13F filings, up 11 from Q3 2025. 15 opened new positions and 5 sold out. The largest holders were Nantahala Capital Management, LLC ($9.6M), Perceptive Advisors LLC ($8.7M) and BIOS Capital Management, LP ($7.4M). 3 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Opus Genetics Inc.
- CUSIP
- 67577R102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 15 | $10.5M |
| Exits | 5 | $102K |
All 13F filers, Q3 2025 → Q4 2025: 9,058,240 shares bought and 286,648 shares sold, net +8,771,592 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 59 holders
| Nantahala Capital Management, LLC | 0.57% | Add +42.9% | 4,781,330 | $9.6M |
| Perceptive Advisors LLC | 0.16% | No change | 4,325,000 | $8.7M |
| BIOS Capital Management, LP | 8.96% | No change | 3,683,429 | $7.4M |
| Balyasny Asset Management L.P. | 0.01% | New | 2,718,029 | $5.5M |
| Vanguard Group Inc. | 0.00% | Add +73.1% | 2,322,897 | $4.7M |
| Millennium Management | 0.00% | New | 2,002,550 | $4.0M |
| Mink Brook Asset Management LLC | 2.12% | Add +34.5% | 1,665,631 | $3.3M |
| Opaleye Management Inc. | 0.30% | Add +1.8% | 1,120,000 | $2.3M |
| Adage Capital Partners Gp, L.L.C. | 0.00% | Add +15.7% | 1,104,996 | $2.2M |
| Bleichroeder LP | 0.26% | No change | 736,842 | $1.5M |
| Geode Capital Management, LLC | 0.00% | Add +7.7% | 504,983 | $1.0M |
| Voss Capital, LP | 0.05% | Reduce -21.4% | 441,891 | $888K |
| Wells Fargo & Company | 0.00% | Add +6290.3% | 241,871 | $486K |
| Susquehanna International Group, LLP | 0.00% | Add +897.5% | 201,635 | $405K |
| Citadel Advisors | 0.00% | Add +59.3% | 180,721 | $363K |
| State Street Corp. | 0.00% | Add +18.8% | 173,253 | $348K |
| Marshall Wace, LLP | 0.00% | New | 157,648 | $317K |
| Two Sigma Investments, LP | 0.00% | Add +39.7% | 151,312 | $304K |
| BlackRock, Inc. | 0.00% | Add +207.8% | 141,897 | $285K |
| Creative Planning | 0.00% | No change | 128,366 | $258K |
| Renaissance Technologies | 0.00% | Reduce -27.3% | 126,309 | $254K |
| UBS Group AG | 0.00% | Add +10060.4% | 89,818 | $181K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 87,900 | $177K |
| Northern Trust Corp. | 0.00% | Add +28.2% | 87,447 | $176K |
| Texas Capital Bank Wealth Management Services Inc | 0.01% | New | 78,000 | $157K |
| Regency Capital Management Inc.\DE | 0.04% | New | 46,000 | $92K |
| Bridgeway Capital Management, LLC | 0.00% | No change | 42,065 | $85K |
| Empowered Funds, LLC | 0.00% | No change | 42,065 | $85K |
| ADAR1 Capital Management, LLC | 0.01% | New | 40,000 | $80K |
| Qube Research & Technologies Ltd | 0.00% | New | 39,978 | $80K |
| Captrust Financial Advisors | 0.00% | No change | 32,000 | $64K |
| Morgan Stanley | 0.00% | Add +0.2% | 28,665 | $58K |
| Blair William & Co. | 0.00% | Add +12.3% | 27,466 | $55K |
| XTX Topco Ltd | 0.00% | Reduce -54.1% | 23,737 | $48K |
| Raymond James Financial Inc. | 0.00% | Reduce -8.9% | 20,508 | $41K |
| Johnson Investment Counsel Inc. | 0.00% | New | 20,000 | $40K |
| Virtu Financial LLC | 0.00% | New | 16,810 | $34K |
| James Investment Research, Inc. | 0.00% | No change | 16,364 | $33K |
| NewEdge Advisors, LLC | 0.00% | No change | 16,364 | $33K |
| Kestra Private Wealth Services, LLC | 0.00% | Reduce -15.8% | 16,000 | $32K |
| Bedel Financial Consulting, Inc. | 0.00% | No change | 15,000 | $30K |
| Osaic Holdings, Inc. | 0.00% | Reduce -0.0% | 13,900 | $28K |
| Occudo Quantitative Strategies LP | 0.00% | New | 12,205 | $25K |
| Stokes Family Office, LLC | 0.00% | No change | 12,120 | $24K |
| Comerica Bank | 0.00% | No change | 12,000 | $24K |
| First City Capital Management, Inc. | 0.01% | New | 11,836 | $24K |
| Miller Financial Services LLC | 0.02% | New | 10,000 | $20K |
| Reliant Investment Partners, LLC | 0.02% | No change | 10,000 | $20K |
| Annandale Capital, LLC | 0.00% | No change | 10,000 | $20K |
| Simplex Trading, LLC | 0.00% | Reduce -72.4% | 9,063 | $18K |
| Hilton Head Capital Partners, LLC | 0.01% | — | 4,472 | $9K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -0.3% | 2,574 | $5K |
| Bank of America Corp. | 0.00% | Add +470.8% | 2,186 | $4K |
| National Bank of Canada | 0.00% | No change | 2,014 | $4K |
| Barclays PLC | 0.00% | No change | 1,900 | $4K |
| International Assets Investment Management, LLC | 0.00% | New | 521 | $1K |
| Royal Bank of Canada | 0.00% | Add +896.7% | 299 | $1K |
| Citigroup Inc. | 0.00% | Add +49500.0% | 496 | $997 |
| Allworth Financial LP | 0.00% | New | 5 | $11 |
"% of holder's portfolio" is IRD's weight in each manager's 13F, not the share of Opus Genetics Inc. the manager owns.