Disc MedicineIRON
13F holders, Q4 2025 (December 31)197holders +29
36new positions
11sold out
5famous investors
$79.40avg. 13F price*
At the end of Q4 2025, 197 institutions reported holding Disc Medicine Inc. (IRON) in their 13F filings, up 29 from Q3 2025. 36 opened new positions and 11 sold out. The largest holders were FMR LLC ($432.8M), BlackRock, Inc. ($180.7M) and Ra Capital Management, L.P. ($156.9M). 5 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Disc Medicine Inc.
- CUSIP
- 254604101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 36 | $213.6M |
| Exits | 11 | $93.4M |
All 13F filers, Q3 2025 → Q4 2025: 8,688,432 shares bought and 4,714,158 shares sold, net +3,974,274 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 197 holders
| FMR LLC | 0.02% | Add +10.4% | 5,450,222 | $432.8M |
| BlackRock, Inc. | 0.00% | Add +12.7% | 2,274,980 | $180.7M |
| Ra Capital Management, L.P. | 1.61% | Add +25.3% | 1,976,132 | $156.9M |
| Vanguard Group Inc. | 0.00% | Add +22.1% | 1,767,680 | $140.4M |
| T. Rowe Price Associates Inc. | 0.01% | Add +28.0% | 1,698,005 | $134.8M |
| JPMorgan Chase & Co. | 0.01% | Add +110.0% | 1,581,127 | $125.6M |
| Wellington Management Group LLP | 0.02% | Add +7.7% | 1,518,274 | $120.6M |
| Atlas Venture Life Science Advisors, LLC | 13.90% | Reduce -29.3% | 1,513,875 | $120.2M |
| Frazier Life Sciences Management, L.P. | 2.70% | Reduce -12.4% | 1,260,000 | $100.1M |
| State Street Corp. | 0.00% | Add +13.6% | 1,187,991 | $94.3M |
| Orbimed Advisors LLC | 1.74% | Reduce -24.6% | 1,067,550 | $84.8M |
| Siren, L.L.C. | 2.34% | Add +8.2% | 988,401 | $78.5M |
| Woodline Partners LP | 0.29% | Add +10.5% | 957,833 | $76.1M |
| Goldman Sachs Group Inc. | 0.01% | Add +42.5% | 754,195 | $59.9M |
| Vestal Point Capital, LP | 2.14% | Add +47.0% | 735,000 | $58.4M |
| Geode Capital Management, LLC | 0.00% | Add +9.0% | 684,958 | $54.4M |
| BVF Inc. | 1.74% | New | 650,000 | $51.6M |
| Jennison Associates LLC | 0.03% | New | 532,079 | $42.3M |
| First Light Asset Management, LLC | 3.18% | Add +126.3% | 523,167 | $41.5M |
| Deerfield Management Company, L.P. | 0.59% | Reduce -44.4% | 511,163 | $40.6M |
| Logos Global Management LP | 2.70% | Add +13.3% | 510,000 | $40.5M |
| Armistice Capital, LLC | 0.97% | Add +14.5% | 499,391 | $39.7M |
| Checkpoint Capital L.P. | 11.40% | Add +5.3% | 452,992 | $36.0M |
| Perceptive Advisors LLC | 0.66% | New | 450,743 | $35.8M |
| Eventide Asset Management, LLC | 0.49% | Add +28.4% | 395,392 | $31.4M |
| Pictet Asset Management Holding SA | 0.03% | Add +10968.6% | 394,374 | $31.3M |
| Assenagon Asset Management S.A. | 0.04% | Add +3329.8% | 357,836 | $28.4M |
| Baker Bros. Advisors LP | 0.16% | No change | 337,050 | $26.8M |
| Palo Alto Investors LP | 3.51% | Add +41.5% | 317,456 | $25.2M |
| Foresite Capital Management V, LLC | 14.45% | No change | 299,069 | $23.7M |
| Saturn V Capital Management LP | 4.35% | Reduce -12.5% | 298,429 | $23.7M |
| Loomis Sayles & Co. L P | 0.03% | New | 282,409 | $22.4M |
| Great Point Partners LLC | 6.44% | New | 250,000 | $19.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +9.0% | 247,039 | $19.6M |
| Aberdeen Group plc | 0.03% | Add +631.0% | 234,358 | $18.6M |
| Northern Trust Corp. | 0.00% | Add +3.9% | 228,070 | $18.1M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -3.0% | 223,575 | $17.7M |
| Balyasny Asset Management L.P. | 0.03% | Reduce -34.4% | 221,761 | $17.6M |
| Opaleye Management Inc. | 2.10% | Add +3.2% | 200,000 | $15.9M |
| TimesSquare Capital Management, LLC | 0.22% | Add +3.1% | 187,777 | $14.9M |
| Millennium Management | 0.01% | Add +14.8% | 184,779 | $14.7M |
| Ensign Peak Advisors, Inc | 0.02% | No change | 177,050 | $14.1M |
| First Turn Management, LLC | 1.39% | Reduce -61.5% | 153,206 | $12.2M |
| Bank of America Corp. | 0.00% | Reduce -15.6% | 135,986 | $10.8M |
| Nantahala Capital Management, LLC | 0.63% | Reduce -53.9% | 132,800 | $10.5M |
| BNP Paribas Financial Markets | 0.01% | Add +224.8% | 122,153 | $9.7M |
| UBS Group AG | 0.00% | Reduce -32.3% | 116,112 | $9.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +25.1% | 114,351 | $9.1M |
| Sofinnova Investments, Inc. | 0.38% | Add +719.1% | 111,010 | $8.8M |
| Catalio Capital Management, LP | 1.55% | Reduce -49.0% | 110,427 | $8.8M |
| Citadel Advisors | 0.01% | Add +99.2% | 100,395 | $8.0M |
| Barclays PLC | 0.00% | Reduce -7.1% | 99,612 | $7.9M |
| DNB Asset Management AS | 0.02% | Add +1425.8% | 84,255 | $6.7M |
| Ameriprise Financial Inc. | 0.00% | Add +11.6% | 82,984 | $6.6M |
| Raymond James Financial Inc. | 0.00% | Reduce -43.3% | 80,274 | $6.2M |
| Victory Capital Management Inc. | 0.00% | Reduce -49.1% | 76,338 | $6.1M |
| Morgan Stanley | 0.00% | Add +33.4% | 74,826 | $5.9M |
| Patient Square Capital LP | 1.26% | No change | 74,000 | $5.9M |
| TD Asset Management Inc | 0.00% | Add +17.5% | 69,634 | $5.5M |
| Bank of New York Mellon Corp | 0.00% | Add +4.5% | 67,707 | $5.4M |
| iA Global Asset Management Inc. | 0.07% | Add +1.4% | 66,430 | $5.3M |
| Tudor Investment Corporation | 0.03% | New | 66,125 | $5.3M |
| Verition Fund Management LLC | 0.03% | Add +936.0% | 63,535 | $5.0M |
| Renaissance Technologies | 0.01% | Add +823.8% | 62,820 | $5.0M |
| Invesco Ltd. | 0.00% | Add +184.8% | 61,070 | $4.8M |
| KVP Capital Advisors, LP | 4.78% | — | 58,250 | $4.6M |
| ExodusPoint Capital Management, LP | 0.05% | New | 58,211 | $4.6M |
| Lazard Asset Management LLC | 0.01% | New | 58,053 | $4.6M |
| Sio Capital Management, LLC | 0.76% | Reduce -79.8% | 57,586 | $4.6M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +10.4% | 52,510 | $4.1M |
| Burkehill Global Management, LP | 0.27% | New | 50,000 | $4.0M |
| Alyeska Investment Group, L.P. | 0.01% | New | 50,000 | $4.0M |
| Brevan Howard Capital Management LP | 0.08% | New | 49,713 | $3.9M |
| Schroder Investment Management Group | 0.00% | Reduce -25.4% | 50,103 | $3.9M |
| Nuveen, LLC | 0.00% | Add +1.6% | 48,471 | $3.8M |
| Nicholas Investment Partners, LP | 0.32% | Reduce -45.4% | 48,082 | $3.8M |
| Swiss National Bank | 0.00% | Add +10.1% | 48,000 | $3.8M |
| Atle Fund Management AB | 1.22% | Add +5.0% | 47,967 | $3.8M |
| Exome Asset Management LLC | 1.83% | Reduce -23.8% | 46,743 | $3.7M |
| NEXTBio Capital Management LP | 1.99% | — | 42,778 | $3.4M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +18774.7% | 40,203 | $3.2M |
| Citigroup Inc. | 0.00% | Add +794.3% | 36,176 | $2.9M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -3.2% | 36,093 | $2.9M |
| Seven Grand Managers, LLC | 0.21% | New | 35,000 | $2.8M |
| Wells Fargo & Company | 0.00% | Add +22.9% | 33,265 | $2.6M |
| Alps Advisors Inc. | 0.01% | Add +84.6% | 31,002 | $2.5M |
| American Century Companies Inc. | 0.00% | Add +8.6% | 30,328 | $2.4M |
| RTW Investments, LP | 0.02% | New | 30,000 | $2.4M |
| Rhumbline Advisers | 0.00% | Reduce -13.5% | 29,833 | $2.4M |
| Zimmer Partners, LP | 0.06% | Reduce -69.5% | 27,500 | $2.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +138.7% | 27,301 | $2.2M |
| Eagle Health Investments LP | 0.47% | New | 27,100 | $2.2M |
| PNC Financial Services Group, Inc. | 0.00% | Add +0.2% | 25,200 | $2.0M |
| Bank of Montreal | 0.00% | Add +39.6% | 24,826 | $2.0M |
| Alliancebernstein L.P. | 0.00% | No change | 24,540 | $1.9M |
| Russell Investments Group, Ltd. | 0.00% | Add +871.4% | 23,683 | $1.9M |
| Legal & General Group Plc | 0.00% | Reduce -5.9% | 23,653 | $1.9M |
| California State Teachers Retirement System | 0.00% | Add +5.3% | 23,256 | $1.8M |
| XTX Topco Ltd | 0.05% | New | 23,094 | $1.8M |
| SG Americas Securities, LLC | 0.00% | Add +161.9% | 21,122 | $1.7M |
"% of holder's portfolio" is IRON's weight in each manager's 13F, not the share of Disc Medicine Inc. the manager owns.